data_XXXX
# 
_struct.entry_id                  XXXX 
_struct.title                     ? 
_struct.pdbx_descriptor           ? 
_struct.pdbx_model_details        
;MODEL GENERATED BY ROSETTA
 VERSION 2019.23+release.b0c18bd
;
_struct.pdbx_details              ? 
_struct.pdbx_CASP_flag            ? 
_struct.pdbx_model_type_details   ? 
# 
_database_2.database_id     PDB 
_database_2.database_code   XXXX 
# 
_exptl.entry_id          XXXX 
_exptl.method            "THEORETICAL MODEL" 
_exptl.crystals_number   ? 
# 
_pdbx_database_status.entry_id                           XXXX 
_pdbx_database_status.ndb_tid                            ? 
_pdbx_database_status.status_code                        . 
_pdbx_database_status.status_code_sf                     ? 
_pdbx_database_status.status_code_mr                     ? 
_pdbx_database_status.status_code_cs                     ? 
_pdbx_database_status.status_coordinates_in_NDB          ? 
_pdbx_database_status.recvd_deposit_form                 ? 
_pdbx_database_status.date_deposition_form               ? 
_pdbx_database_status.recvd_coordinates                  ? 
_pdbx_database_status.date_coordinates                   ? 
_pdbx_database_status.recvd_struct_fact                  ? 
_pdbx_database_status.date_struct_fact                   ? 
_pdbx_database_status.recvd_internal_approval            ? 
_pdbx_database_status.recvd_nmr_constraints              ? 
_pdbx_database_status.date_nmr_constraints               ? 
_pdbx_database_status.recvd_chemical_shifts              ? 
_pdbx_database_status.date_chemical_shifts               ? 
_pdbx_database_status.recvd_manuscript                   ? 
_pdbx_database_status.date_manuscript                    ? 
_pdbx_database_status.name_depositor                     ? 
_pdbx_database_status.pdbx_annotator                     ? 
_pdbx_database_status.recvd_author_approval              ? 
_pdbx_database_status.date_author_approval               ? 
_pdbx_database_status.recvd_initial_deposition_date      ? 
_pdbx_database_status.date_submitted                     ? 
_pdbx_database_status.author_approval_type               ? 
_pdbx_database_status.author_release_status_code         ? 
_pdbx_database_status.auth_req_rel_date                  ? 
_pdbx_database_status.date_revised                       ? 
_pdbx_database_status.revision_id                        ? 
_pdbx_database_status.replaced_entry_id                  ? 
_pdbx_database_status.revision_description               ? 
_pdbx_database_status.date_of_NDB_release                ? 
_pdbx_database_status.date_released_to_PDB               ? 
_pdbx_database_status.date_of_PDB_release                ? 
_pdbx_database_status.date_of_sf_release                 ? 
_pdbx_database_status.date_of_mr_release                 ? 
_pdbx_database_status.date_of_cs_release                 ? 
_pdbx_database_status.date_hold_coordinates              ? 
_pdbx_database_status.date_hold_struct_fact              ? 
_pdbx_database_status.hold_for_publication               ? 
_pdbx_database_status.date_hold_nmr_constraints          ? 
_pdbx_database_status.date_hold_chemical_shifts          ? 
_pdbx_database_status.dep_release_code_coordinates       ? 
_pdbx_database_status.dep_release_code_struct_fact       ? 
_pdbx_database_status.dep_release_code_nmr_constraints   ? 
_pdbx_database_status.dep_release_code_chemical_shifts   ? 
_pdbx_database_status.dep_release_code_sequence          ? 
_pdbx_database_status.pdb_date_of_author_approval        ? 
_pdbx_database_status.deposit_site                       ? 
_pdbx_database_status.process_site                       ? 
_pdbx_database_status.skip_PDB_REMARK                    ? 
_pdbx_database_status.SG_entry                           ? 
_pdbx_database_status.date_begin_deposition              ? 
_pdbx_database_status.date_author_release_request        ? 
_pdbx_database_status.date_begin_release_preparation     ? 
_pdbx_database_status.date_begin_processing              ? 
_pdbx_database_status.date_end_processing                ? 
_pdbx_database_status.pdb_format_compatible              Y 
_pdbx_database_status.title_suppression                  ? 
_pdbx_database_status.methods_development_category       ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           "polypeptide(L)" 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;KYLLPTAAAGLLLLAAQPAMAQMQLVQSGTEVKKPGESLKISCKGSGYGFITYWIGWVRQMPGKGLEWMGIIYPGDSETR
YSPSFQGQVTISADKSINTAYLQWSSLKASDTAIYYCAGGSGISTPMDVWGQGTTVTVSSGSGGGGSDIQLTQSPDSLAV
SLGERATINCKSSQSVLYSSINKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYY
CQQYYSTPYTFGQGTKVEIKKHHHHHHC
;
_entity_poly.pdbx_seq_one_letter_code_can   
;KYLLPTAAAGLLLLAAQPAMAQMQLVQSGTEVKKPGESLKISCKGSGYGFITYWIGWVRQMPGKGLEWMGIIYPGDSETR
YSPSFQGQVTISADKSINTAYLQWSSLKASDTAIYYCAGGSGISTPMDVWGQGTTVTVSSGSGGGGSDIQLTQSPDSLAV
SLGERATINCKSSQSVLYSSINKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYY
CQQYYSTPYTFGQGTKVEIKKHHHHHHC
;
_entity_poly.pdbx_sequence_evidence_code    "derived from coordinates" 
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   LYS n 
1 2   TYR n 
1 3   LEU n 
1 4   LEU n 
1 5   PRO n 
1 6   THR n 
1 7   ALA n 
1 8   ALA n 
1 9   ALA n 
1 10  GLY n 
1 11  LEU n 
1 12  LEU n 
1 13  LEU n 
1 14  LEU n 
1 15  ALA n 
1 16  ALA n 
1 17  GLN n 
1 18  PRO n 
1 19  ALA n 
1 20  MET n 
1 21  ALA n 
1 22  GLN n 
1 23  MET n 
1 24  GLN n 
1 25  LEU n 
1 26  VAL n 
1 27  GLN n 
1 28  SER n 
1 29  GLY n 
1 30  THR n 
1 31  GLU n 
1 32  VAL n 
1 33  LYS n 
1 34  LYS n 
1 35  PRO n 
1 36  GLY n 
1 37  GLU n 
1 38  SER n 
1 39  LEU n 
1 40  LYS n 
1 41  ILE n 
1 42  SER n 
1 43  CYS n 
1 44  LYS n 
1 45  GLY n 
1 46  SER n 
1 47  GLY n 
1 48  TYR n 
1 49  GLY n 
1 50  PHE n 
1 51  ILE n 
1 52  THR n 
1 53  TYR n 
1 54  TRP n 
1 55  ILE n 
1 56  GLY n 
1 57  TRP n 
1 58  VAL n 
1 59  ARG n 
1 60  GLN n 
1 61  MET n 
1 62  PRO n 
1 63  GLY n 
1 64  LYS n 
1 65  GLY n 
1 66  LEU n 
1 67  GLU n 
1 68  TRP n 
1 69  MET n 
1 70  GLY n 
1 71  ILE n 
1 72  ILE n 
1 73  TYR n 
1 74  PRO n 
1 75  GLY n 
1 76  ASP n 
1 77  SER n 
1 78  GLU n 
1 79  THR n 
1 80  ARG n 
1 81  TYR n 
1 82  SER n 
1 83  PRO n 
1 84  SER n 
1 85  PHE n 
1 86  GLN n 
1 87  GLY n 
1 88  GLN n 
1 89  VAL n 
1 90  THR n 
1 91  ILE n 
1 92  SER n 
1 93  ALA n 
1 94  ASP n 
1 95  LYS n 
1 96  SER n 
1 97  ILE n 
1 98  ASN n 
1 99  THR n 
1 100 ALA n 
1 101 TYR n 
1 102 LEU n 
1 103 GLN n 
1 104 TRP n 
1 105 SER n 
1 106 SER n 
1 107 LEU n 
1 108 LYS n 
1 109 ALA n 
1 110 SER n 
1 111 ASP n 
1 112 THR n 
1 113 ALA n 
1 114 ILE n 
1 115 TYR n 
1 116 TYR n 
1 117 CYS n 
1 118 ALA n 
1 119 GLY n 
1 120 GLY n 
1 121 SER n 
1 122 GLY n 
1 123 ILE n 
1 124 SER n 
1 125 THR n 
1 126 PRO n 
1 127 MET n 
1 128 ASP n 
1 129 VAL n 
1 130 TRP n 
1 131 GLY n 
1 132 GLN n 
1 133 GLY n 
1 134 THR n 
1 135 THR n 
1 136 VAL n 
1 137 THR n 
1 138 VAL n 
1 139 SER n 
1 140 SER n 
1 141 GLY n 
1 142 SER n 
1 143 GLY n 
1 144 GLY n 
1 145 GLY n 
1 146 GLY n 
1 147 SER n 
1 148 ASP n 
1 149 ILE n 
1 150 GLN n 
1 151 LEU n 
1 152 THR n 
1 153 GLN n 
1 154 SER n 
1 155 PRO n 
1 156 ASP n 
1 157 SER n 
1 158 LEU n 
1 159 ALA n 
1 160 VAL n 
1 161 SER n 
1 162 LEU n 
1 163 GLY n 
1 164 GLU n 
1 165 ARG n 
1 166 ALA n 
1 167 THR n 
1 168 ILE n 
1 169 ASN n 
1 170 CYS n 
1 171 LYS n 
1 172 SER n 
1 173 SER n 
1 174 GLN n 
1 175 SER n 
1 176 VAL n 
1 177 LEU n 
1 178 TYR n 
1 179 SER n 
1 180 SER n 
1 181 ILE n 
1 182 ASN n 
1 183 LYS n 
1 184 ASN n 
1 185 TYR n 
1 186 LEU n 
1 187 ALA n 
1 188 TRP n 
1 189 TYR n 
1 190 GLN n 
1 191 GLN n 
1 192 LYS n 
1 193 PRO n 
1 194 GLY n 
1 195 GLN n 
1 196 PRO n 
1 197 PRO n 
1 198 LYS n 
1 199 LEU n 
1 200 LEU n 
1 201 ILE n 
1 202 TYR n 
1 203 TRP n 
1 204 ALA n 
1 205 SER n 
1 206 THR n 
1 207 ARG n 
1 208 GLU n 
1 209 SER n 
1 210 GLY n 
1 211 VAL n 
1 212 PRO n 
1 213 ASP n 
1 214 ARG n 
1 215 PHE n 
1 216 SER n 
1 217 GLY n 
1 218 SER n 
1 219 GLY n 
1 220 SER n 
1 221 GLY n 
1 222 THR n 
1 223 ASP n 
1 224 PHE n 
1 225 THR n 
1 226 LEU n 
1 227 THR n 
1 228 ILE n 
1 229 SER n 
1 230 SER n 
1 231 LEU n 
1 232 GLN n 
1 233 ALA n 
1 234 GLU n 
1 235 ASP n 
1 236 VAL n 
1 237 ALA n 
1 238 VAL n 
1 239 TYR n 
1 240 TYR n 
1 241 CYS n 
1 242 GLN n 
1 243 GLN n 
1 244 TYR n 
1 245 TYR n 
1 246 SER n 
1 247 THR n 
1 248 PRO n 
1 249 TYR n 
1 250 THR n 
1 251 PHE n 
1 252 GLY n 
1 253 GLN n 
1 254 GLY n 
1 255 THR n 
1 256 LYS n 
1 257 VAL n 
1 258 GLU n 
1 259 ILE n 
1 260 LYS n 
1 261 LYS n 
1 262 HIS n 
1 263 HIS n 
1 264 HIS n 
1 265 HIS n 
1 266 HIS n 
1 267 HIS n 
1 268 CYS n 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           ? 
_entity.formula_weight             29000.527 
_entity.pdbx_number_of_molecules   1 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   LYS 1   1   1   LYS LYS A . n 
A 1 2   TYR 2   2   2   TYR TYR A . n 
A 1 3   LEU 3   3   3   LEU LEU A . n 
A 1 4   LEU 4   4   4   LEU LEU A . n 
A 1 5   PRO 5   5   5   PRO PRO A . n 
A 1 6   THR 6   6   6   THR THR A . n 
A 1 7   ALA 7   7   7   ALA ALA A . n 
A 1 8   ALA 8   8   8   ALA ALA A . n 
A 1 9   ALA 9   9   9   ALA ALA A . n 
A 1 10  GLY 10  10  10  GLY GLY A . n 
A 1 11  LEU 11  11  11  LEU LEU A . n 
A 1 12  LEU 12  12  12  LEU LEU A . n 
A 1 13  LEU 13  13  13  LEU LEU A . n 
A 1 14  LEU 14  14  14  LEU LEU A . n 
A 1 15  ALA 15  15  15  ALA ALA A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  GLN 17  17  17  GLN GLN A . n 
A 1 18  PRO 18  18  18  PRO PRO A . n 
A 1 19  ALA 19  19  19  ALA ALA A . n 
A 1 20  MET 20  20  20  MET MET A . n 
A 1 21  ALA 21  21  21  ALA ALA A . n 
A 1 22  GLN 22  22  22  GLN GLN A . n 
A 1 23  MET 23  23  23  MET MET A . n 
A 1 24  GLN 24  24  24  GLN GLN A . n 
A 1 25  LEU 25  25  25  LEU LEU A . n 
A 1 26  VAL 26  26  26  VAL VAL A . n 
A 1 27  GLN 27  27  27  GLN GLN A . n 
A 1 28  SER 28  28  28  SER SER A . n 
A 1 29  GLY 29  29  29  GLY GLY A . n 
A 1 30  THR 30  30  30  THR THR A . n 
A 1 31  GLU 31  31  31  GLU GLU A . n 
A 1 32  VAL 32  32  32  VAL VAL A . n 
A 1 33  LYS 33  33  33  LYS LYS A . n 
A 1 34  LYS 34  34  34  LYS LYS A . n 
A 1 35  PRO 35  35  35  PRO PRO A . n 
A 1 36  GLY 36  36  36  GLY GLY A . n 
A 1 37  GLU 37  37  37  GLU GLU A . n 
A 1 38  SER 38  38  38  SER SER A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  LYS 40  40  40  LYS LYS A . n 
A 1 41  ILE 41  41  41  ILE ILE A . n 
A 1 42  SER 42  42  42  SER SER A . n 
A 1 43  CYS 43  43  43  CYS CYS A . n 
A 1 44  LYS 44  44  44  LYS LYS A . n 
A 1 45  GLY 45  45  45  GLY GLY A . n 
A 1 46  SER 46  46  46  SER SER A . n 
A 1 47  GLY 47  47  47  GLY GLY A . n 
A 1 48  TYR 48  48  48  TYR TYR A . n 
A 1 49  GLY 49  49  49  GLY GLY A . n 
A 1 50  PHE 50  50  50  PHE PHE A . n 
A 1 51  ILE 51  51  51  ILE ILE A . n 
A 1 52  THR 52  52  52  THR THR A . n 
A 1 53  TYR 53  53  53  TYR TYR A . n 
A 1 54  TRP 54  54  54  TRP TRP A . n 
A 1 55  ILE 55  55  55  ILE ILE A . n 
A 1 56  GLY 56  56  56  GLY GLY A . n 
A 1 57  TRP 57  57  57  TRP TRP A . n 
A 1 58  VAL 58  58  58  VAL VAL A . n 
A 1 59  ARG 59  59  59  ARG ARG A . n 
A 1 60  GLN 60  60  60  GLN GLN A . n 
A 1 61  MET 61  61  61  MET MET A . n 
A 1 62  PRO 62  62  62  PRO PRO A . n 
A 1 63  GLY 63  63  63  GLY GLY A . n 
A 1 64  LYS 64  64  64  LYS LYS A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  LEU 66  66  66  LEU LEU A . n 
A 1 67  GLU 67  67  67  GLU GLU A . n 
A 1 68  TRP 68  68  68  TRP TRP A . n 
A 1 69  MET 69  69  69  MET MET A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  ILE 71  71  71  ILE ILE A . n 
A 1 72  ILE 72  72  72  ILE ILE A . n 
A 1 73  TYR 73  73  73  TYR TYR A . n 
A 1 74  PRO 74  74  74  PRO PRO A . n 
A 1 75  GLY 75  75  75  GLY GLY A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  SER 77  77  77  SER SER A . n 
A 1 78  GLU 78  78  78  GLU GLU A . n 
A 1 79  THR 79  79  79  THR THR A . n 
A 1 80  ARG 80  80  80  ARG ARG A . n 
A 1 81  TYR 81  81  81  TYR TYR A . n 
A 1 82  SER 82  82  82  SER SER A . n 
A 1 83  PRO 83  83  83  PRO PRO A . n 
A 1 84  SER 84  84  84  SER SER A . n 
A 1 85  PHE 85  85  85  PHE PHE A . n 
A 1 86  GLN 86  86  86  GLN GLN A . n 
A 1 87  GLY 87  87  87  GLY GLY A . n 
A 1 88  GLN 88  88  88  GLN GLN A . n 
A 1 89  VAL 89  89  89  VAL VAL A . n 
A 1 90  THR 90  90  90  THR THR A . n 
A 1 91  ILE 91  91  91  ILE ILE A . n 
A 1 92  SER 92  92  92  SER SER A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  ASP 94  94  94  ASP ASP A . n 
A 1 95  LYS 95  95  95  LYS LYS A . n 
A 1 96  SER 96  96  96  SER SER A . n 
A 1 97  ILE 97  97  97  ILE ILE A . n 
A 1 98  ASN 98  98  98  ASN ASN A . n 
A 1 99  THR 99  99  99  THR THR A . n 
A 1 100 ALA 100 100 100 ALA ALA A . n 
A 1 101 TYR 101 101 101 TYR TYR A . n 
A 1 102 LEU 102 102 102 LEU LEU A . n 
A 1 103 GLN 103 103 103 GLN GLN A . n 
A 1 104 TRP 104 104 104 TRP TRP A . n 
A 1 105 SER 105 105 105 SER SER A . n 
A 1 106 SER 106 106 106 SER SER A . n 
A 1 107 LEU 107 107 107 LEU LEU A . n 
A 1 108 LYS 108 108 108 LYS LYS A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 SER 110 110 110 SER SER A . n 
A 1 111 ASP 111 111 111 ASP ASP A . n 
A 1 112 THR 112 112 112 THR THR A . n 
A 1 113 ALA 113 113 113 ALA ALA A . n 
A 1 114 ILE 114 114 114 ILE ILE A . n 
A 1 115 TYR 115 115 115 TYR TYR A . n 
A 1 116 TYR 116 116 116 TYR TYR A . n 
A 1 117 CYS 117 117 117 CYS CYS A . n 
A 1 118 ALA 118 118 118 ALA ALA A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 GLY 120 120 120 GLY GLY A . n 
A 1 121 SER 121 121 121 SER SER A . n 
A 1 122 GLY 122 122 122 GLY GLY A . n 
A 1 123 ILE 123 123 123 ILE ILE A . n 
A 1 124 SER 124 124 124 SER SER A . n 
A 1 125 THR 125 125 125 THR THR A . n 
A 1 126 PRO 126 126 126 PRO PRO A . n 
A 1 127 MET 127 127 127 MET MET A . n 
A 1 128 ASP 128 128 128 ASP ASP A . n 
A 1 129 VAL 129 129 129 VAL VAL A . n 
A 1 130 TRP 130 130 130 TRP TRP A . n 
A 1 131 GLY 131 131 131 GLY GLY A . n 
A 1 132 GLN 132 132 132 GLN GLN A . n 
A 1 133 GLY 133 133 133 GLY GLY A . n 
A 1 134 THR 134 134 134 THR THR A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 VAL 136 136 136 VAL VAL A . n 
A 1 137 THR 137 137 137 THR THR A . n 
A 1 138 VAL 138 138 138 VAL VAL A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 SER 140 140 140 SER SER A . n 
A 1 141 GLY 141 141 141 GLY GLY A . n 
A 1 142 SER 142 142 142 SER SER A . n 
A 1 143 GLY 143 143 143 GLY GLY A . n 
A 1 144 GLY 144 144 144 GLY GLY A . n 
A 1 145 GLY 145 145 145 GLY GLY A . n 
A 1 146 GLY 146 146 146 GLY GLY A . n 
A 1 147 SER 147 147 147 SER SER A . n 
A 1 148 ASP 148 148 148 ASP ASP A . n 
A 1 149 ILE 149 149 149 ILE ILE A . n 
A 1 150 GLN 150 150 150 GLN GLN A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 THR 152 152 152 THR THR A . n 
A 1 153 GLN 153 153 153 GLN GLN A . n 
A 1 154 SER 154 154 154 SER SER A . n 
A 1 155 PRO 155 155 155 PRO PRO A . n 
A 1 156 ASP 156 156 156 ASP ASP A . n 
A 1 157 SER 157 157 157 SER SER A . n 
A 1 158 LEU 158 158 158 LEU LEU A . n 
A 1 159 ALA 159 159 159 ALA ALA A . n 
A 1 160 VAL 160 160 160 VAL VAL A . n 
A 1 161 SER 161 161 161 SER SER A . n 
A 1 162 LEU 162 162 162 LEU LEU A . n 
A 1 163 GLY 163 163 163 GLY GLY A . n 
A 1 164 GLU 164 164 164 GLU GLU A . n 
A 1 165 ARG 165 165 165 ARG ARG A . n 
A 1 166 ALA 166 166 166 ALA ALA A . n 
A 1 167 THR 167 167 167 THR THR A . n 
A 1 168 ILE 168 168 168 ILE ILE A . n 
A 1 169 ASN 169 169 169 ASN ASN A . n 
A 1 170 CYS 170 170 170 CYS CYS A . n 
A 1 171 LYS 171 171 171 LYS LYS A . n 
A 1 172 SER 172 172 172 SER SER A . n 
A 1 173 SER 173 173 173 SER SER A . n 
A 1 174 GLN 174 174 174 GLN GLN A . n 
A 1 175 SER 175 175 175 SER SER A . n 
A 1 176 VAL 176 176 176 VAL VAL A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 TYR 178 178 178 TYR TYR A . n 
A 1 179 SER 179 179 179 SER SER A . n 
A 1 180 SER 180 180 180 SER SER A . n 
A 1 181 ILE 181 181 181 ILE ILE A . n 
A 1 182 ASN 182 182 182 ASN ASN A . n 
A 1 183 LYS 183 183 183 LYS LYS A . n 
A 1 184 ASN 184 184 184 ASN ASN A . n 
A 1 185 TYR 185 185 185 TYR TYR A . n 
A 1 186 LEU 186 186 186 LEU LEU A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 TRP 188 188 188 TRP TRP A . n 
A 1 189 TYR 189 189 189 TYR TYR A . n 
A 1 190 GLN 190 190 190 GLN GLN A . n 
A 1 191 GLN 191 191 191 GLN GLN A . n 
A 1 192 LYS 192 192 192 LYS LYS A . n 
A 1 193 PRO 193 193 193 PRO PRO A . n 
A 1 194 GLY 194 194 194 GLY GLY A . n 
A 1 195 GLN 195 195 195 GLN GLN A . n 
A 1 196 PRO 196 196 196 PRO PRO A . n 
A 1 197 PRO 197 197 197 PRO PRO A . n 
A 1 198 LYS 198 198 198 LYS LYS A . n 
A 1 199 LEU 199 199 199 LEU LEU A . n 
A 1 200 LEU 200 200 200 LEU LEU A . n 
A 1 201 ILE 201 201 201 ILE ILE A . n 
A 1 202 TYR 202 202 202 TYR TYR A . n 
A 1 203 TRP 203 203 203 TRP TRP A . n 
A 1 204 ALA 204 204 204 ALA ALA A . n 
A 1 205 SER 205 205 205 SER SER A . n 
A 1 206 THR 206 206 206 THR THR A . n 
A 1 207 ARG 207 207 207 ARG ARG A . n 
A 1 208 GLU 208 208 208 GLU GLU A . n 
A 1 209 SER 209 209 209 SER SER A . n 
A 1 210 GLY 210 210 210 GLY GLY A . n 
A 1 211 VAL 211 211 211 VAL VAL A . n 
A 1 212 PRO 212 212 212 PRO PRO A . n 
A 1 213 ASP 213 213 213 ASP ASP A . n 
A 1 214 ARG 214 214 214 ARG ARG A . n 
A 1 215 PHE 215 215 215 PHE PHE A . n 
A 1 216 SER 216 216 216 SER SER A . n 
A 1 217 GLY 217 217 217 GLY GLY A . n 
A 1 218 SER 218 218 218 SER SER A . n 
A 1 219 GLY 219 219 219 GLY GLY A . n 
A 1 220 SER 220 220 220 SER SER A . n 
A 1 221 GLY 221 221 221 GLY GLY A . n 
A 1 222 THR 222 222 222 THR THR A . n 
A 1 223 ASP 223 223 223 ASP ASP A . n 
A 1 224 PHE 224 224 224 PHE PHE A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 LEU 226 226 226 LEU LEU A . n 
A 1 227 THR 227 227 227 THR THR A . n 
A 1 228 ILE 228 228 228 ILE ILE A . n 
A 1 229 SER 229 229 229 SER SER A . n 
A 1 230 SER 230 230 230 SER SER A . n 
A 1 231 LEU 231 231 231 LEU LEU A . n 
A 1 232 GLN 232 232 232 GLN GLN A . n 
A 1 233 ALA 233 233 233 ALA ALA A . n 
A 1 234 GLU 234 234 234 GLU GLU A . n 
A 1 235 ASP 235 235 235 ASP ASP A . n 
A 1 236 VAL 236 236 236 VAL VAL A . n 
A 1 237 ALA 237 237 237 ALA ALA A . n 
A 1 238 VAL 238 238 238 VAL VAL A . n 
A 1 239 TYR 239 239 239 TYR TYR A . n 
A 1 240 TYR 240 240 240 TYR TYR A . n 
A 1 241 CYS 241 241 241 CYS CYS A . n 
A 1 242 GLN 242 242 242 GLN GLN A . n 
A 1 243 GLN 243 243 243 GLN GLN A . n 
A 1 244 TYR 244 244 244 TYR TYR A . n 
A 1 245 TYR 245 245 245 TYR TYR A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 THR 247 247 247 THR THR A . n 
A 1 248 PRO 248 248 248 PRO PRO A . n 
A 1 249 TYR 249 249 249 TYR TYR A . n 
A 1 250 THR 250 250 250 THR THR A . n 
A 1 251 PHE 251 251 251 PHE PHE A . n 
A 1 252 GLY 252 252 252 GLY GLY A . n 
A 1 253 GLN 253 253 253 GLN GLN A . n 
A 1 254 GLY 254 254 254 GLY GLY A . n 
A 1 255 THR 255 255 255 THR THR A . n 
A 1 256 LYS 256 256 256 LYS LYS A . n 
A 1 257 VAL 257 257 257 VAL VAL A . n 
A 1 258 GLU 258 258 258 GLU GLU A . n 
A 1 259 ILE 259 259 259 ILE ILE A . n 
A 1 260 LYS 260 260 260 LYS LYS A . n 
A 1 261 LYS 261 261 261 LYS LYS A . n 
A 1 262 HIS 262 262 262 HIS HIS A . n 
A 1 263 HIS 263 263 263 HIS HIS A . n 
A 1 264 HIS 264 264 264 HIS HIS A . n 
A 1 265 HIS 265 265 265 HIS HIS A . n 
A 1 266 HIS 266 266 266 HIS HIS A . n 
A 1 267 HIS 267 267 267 HIS HIS A . n 
A 1 268 CYS 268 268 268 CYS CYS A . n 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA "L-peptide linking" y ALANINE         ? "C3 H7 N O2"     89.093  
ARG "L-peptide linking" y ARGININE        ? "C6 H15 N4 O2 1" 175.209 
ASN "L-peptide linking" y ASPARAGINE      ? "C4 H8 N2 O3"    132.118 
ASP "L-peptide linking" y "ASPARTIC ACID" ? "C4 H7 N O4"     133.103 
CYS "L-peptide linking" y CYSTEINE        ? "C3 H7 N O2 S"   121.158 
GLN "L-peptide linking" y GLUTAMINE       ? "C5 H10 N2 O3"   146.144 
GLU "L-peptide linking" y "GLUTAMIC ACID" ? "C5 H9 N O4"     147.129 
GLY "peptide linking"   y GLYCINE         ? "C2 H5 N O2"     75.067  
HIS "L-peptide linking" y HISTIDINE       ? "C6 H10 N3 O2 1" 156.162 
ILE "L-peptide linking" y ISOLEUCINE      ? "C6 H13 N O2"    131.173 
LEU "L-peptide linking" y LEUCINE         ? "C6 H13 N O2"    131.173 
LYS "L-peptide linking" y LYSINE          ? "C6 H15 N2 O2 1" 147.195 
MET "L-peptide linking" y METHIONINE      ? "C5 H11 N O2 S"  149.211 
PHE "L-peptide linking" y PHENYLALANINE   ? "C9 H11 N O2"    165.189 
PRO "L-peptide linking" y PROLINE         ? "C5 H9 N O2"     115.130 
SER "L-peptide linking" y SERINE          ? "C3 H7 N O3"     105.093 
THR "L-peptide linking" y THREONINE       ? "C4 H9 N O3"     119.119 
TRP "L-peptide linking" y TRYPTOPHAN      ? "C11 H12 N2 O2"  204.225 
TYR "L-peptide linking" y TYROSINE        ? "C9 H11 N O3"    181.189 
VAL "L-peptide linking" y VALINE          ? "C5 H11 N O2"    117.146 
# 
_struct_asym.id                            A 
_struct_asym.pdbx_PDB_id                   A 
_struct_asym.pdbx_alt_id                   A 
_struct_asym.pdbx_blank_PDB_chainid_flag   N 
_struct_asym.pdbx_type                     ATOMP 
_struct_asym.pdbx_order                    1 
_struct_asym.pdbx_modified                 N 
_struct_asym.entity_id                     1 
_struct_asym.details                       ? 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 1 LEU A 4   ? ALA A 19  ? LEU A 4   ALA A 19  1 ? 16 
HELX_P HELX_P2 2 PRO A 83  ? PHE A 85  ? PRO A 83  PHE A 85  1 ? 3  
HELX_P HELX_P3 3 ALA A 109 ? ASP A 111 ? ALA A 109 ASP A 111 1 ? 3  
HELX_P HELX_P4 4 TYR A 178 ? LYS A 183 ? TYR A 178 LYS A 183 1 ? 6  
HELX_P HELX_P5 5 ALA A 233 ? ASP A 235 ? ALA A 233 ASP A 235 1 ? 3  
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 121 A . ? SER 121 A GLY 122 A ? GLY 122 A 1 -4.90 
2 GLY 254 A . ? GLY 254 A THR 255 A ? THR 255 A 1 -2.44 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
1  ? 1 ? 
2  ? 1 ? 
3  ? 1 ? 
4  ? 1 ? 
5  ? 1 ? 
6  ? 1 ? 
7  ? 1 ? 
8  ? 1 ? 
9  ? 1 ? 
10 ? 1 ? 
11 ? 1 ? 
12 ? 1 ? 
13 ? 1 ? 
14 ? 1 ? 
15 ? 1 ? 
16 ? 1 ? 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
1  1 THR A 30  ? LYS A 33  ? THR A 30  LYS A 33  
2  1 LEU A 39  ? LYS A 44  ? LEU A 39  LYS A 44  
3  1 TRP A 54  ? GLN A 60  ? TRP A 54  GLN A 60  
4  1 LEU A 66  ? ILE A 72  ? LEU A 66  ILE A 72  
5  1 THR A 79  ? TYR A 81  ? THR A 79  TYR A 81  
6  1 VAL A 89  ? ASP A 94  ? VAL A 89  ASP A 94  
7  1 THR A 99  ? TRP A 104 ? THR A 99  TRP A 104 
8  1 ALA A 113 ? GLY A 120 ? ALA A 113 GLY A 120 
9  1 GLY A 133 ? VAL A 138 ? GLY A 133 VAL A 138 
10 1 ALA A 166 ? LYS A 171 ? ALA A 166 LYS A 171 
11 1 TYR A 185 ? GLN A 191 ? TYR A 185 GLN A 191 
12 1 LYS A 198 ? ILE A 201 ? LYS A 198 ILE A 201 
13 1 PHE A 215 ? SER A 220 ? PHE A 215 SER A 220 
14 1 ASP A 223 ? ILE A 228 ? ASP A 223 ILE A 228 
15 1 VAL A 238 ? TYR A 244 ? VAL A 238 TYR A 244 
16 1 THR A 250 ? LYS A 256 ? THR A 250 LYS A 256 
# 
_atom_sites.entry_id                    XXXX 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
# 
_database_PDB_remark.id     220 
_database_PDB_remark.text   
;EXPERIMENTAL DETAILS
 EXPERIMENT TYPE                : THEORETICAL MODELLING
 DATE OF DATA COLLECTION        : 25-AUG-21

REMARK: MODEL GENERATED BY ROSETTA
 VERSION 2019.23+release.b0c18bd
;
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 HA  A GLN 17  ? ? HA A PRO 18  ? ? 0.31 
2  1 O   A PRO 62  ? ? H  A GLY 63  ? ? 1.06 
3  1 HA  A HIS 264 ? ? H  A HIS 265 ? ? 1.22 
4  1 HG  A SER 172 ? ? H  A CYS 268 ? ? 1.23 
5  1 HG1 A THR 255 ? ? H  A LYS 256 ? ? 1.23 
6  1 CA  A GLN 17  ? ? HA A PRO 18  ? ? 1.25 
7  1 HA  A ILE 149 ? ? H  A GLN 150 ? ? 1.31 
8  1 HA  A GLN 17  ? ? CA A PRO 18  ? ? 1.35 
9  1 O   A GLY 122 ? ? HA A ILE 123 ? ? 1.36 
10 1 O   A PRO 62  ? ? N  A GLY 63  ? ? 1.38 
11 1 C   A LEU 162 ? ? H  A GLY 163 ? ? 1.50 
12 1 O   A ASP 235 ? ? HH A TYR 239 ? ? 1.50 
13 1 C   A TYR 202 ? ? H  A TRP 203 ? ? 1.52 
14 1 C   A ASP 76  ? ? H  A SER 77  ? ? 1.55 
15 1 OG  A SER 172 ? ? H  A CYS 268 ? ? 1.58 
16 1 O   A PHE 50  ? ? HA A ILE 51  ? ? 1.59 
17 1 O   A SER 105 ? ? N  A SER 106 ? ? 1.69 
18 1 O   A THR 152 ? ? N  A GLN 153 ? ? 1.76 
19 1 O   A SER 229 ? ? N  A SER 230 ? ? 1.77 
20 1 O   A ASP 235 ? ? OH A TYR 239 ? ? 2.02 
21 1 OG  A SER 172 ? ? N  A HIS 267 ? ? 2.19 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1   1 C  A LEU 4   ? ? N  A PRO 5   ? ? 1.476 1.338 0.138  0.019 Y 
2   1 C  A PRO 5   ? ? N  A THR 6   ? ? 1.527 1.336 0.191  0.023 Y 
3   1 C  A THR 6   ? ? N  A ALA 7   ? ? 1.538 1.336 0.202  0.023 Y 
4   1 C  A ALA 7   ? ? N  A ALA 8   ? ? 1.525 1.336 0.189  0.023 Y 
5   1 C  A ALA 8   ? ? N  A ALA 9   ? ? 1.497 1.336 0.161  0.023 Y 
6   1 C  A ALA 9   ? ? N  A GLY 10  ? ? 1.512 1.336 0.176  0.023 Y 
7   1 C  A GLY 10  ? ? O  A GLY 10  ? ? 1.331 1.232 0.099  0.016 N 
8   1 C  A GLY 10  ? ? N  A LEU 11  ? ? 1.505 1.336 0.169  0.023 Y 
9   1 C  A LEU 11  ? ? O  A LEU 11  ? ? 1.356 1.229 0.127  0.019 N 
10  1 C  A LEU 11  ? ? N  A LEU 12  ? ? 1.529 1.336 0.193  0.023 Y 
11  1 C  A LEU 12  ? ? N  A LEU 13  ? ? 1.526 1.336 0.190  0.023 Y 
12  1 C  A LEU 13  ? ? O  A LEU 13  ? ? 1.360 1.229 0.131  0.019 N 
13  1 C  A LEU 13  ? ? N  A LEU 14  ? ? 1.523 1.336 0.187  0.023 Y 
14  1 C  A LEU 14  ? ? N  A ALA 15  ? ? 1.549 1.336 0.213  0.023 Y 
15  1 C  A ALA 15  ? ? N  A ALA 16  ? ? 1.548 1.336 0.212  0.023 Y 
16  1 C  A ALA 16  ? ? N  A GLN 17  ? ? 1.512 1.336 0.176  0.023 Y 
17  1 C  A GLN 17  ? ? O  A GLN 17  ? ? 1.483 1.229 0.254  0.019 N 
18  1 C  A GLN 17  ? ? N  A PRO 18  ? ? 1.499 1.338 0.161  0.019 Y 
19  1 N  A PRO 18  ? ? CA A PRO 18  ? ? 1.310 1.468 -0.158 0.017 N 
20  1 CD A PRO 18  ? ? N  A PRO 18  ? ? 1.786 1.474 0.312  0.014 N 
21  1 CA A PRO 18  ? ? C  A PRO 18  ? ? 1.382 1.524 -0.142 0.020 N 
22  1 C  A PRO 18  ? ? N  A ALA 19  ? ? 1.528 1.336 0.192  0.023 Y 
23  1 C  A ALA 19  ? ? O  A ALA 19  ? ? 1.363 1.229 0.134  0.019 N 
24  1 C  A ALA 19  ? ? N  A MET 20  ? ? 1.518 1.336 0.182  0.023 Y 
25  1 N  A MET 20  ? ? CA A MET 20  ? ? 1.326 1.459 -0.133 0.020 N 
26  1 C  A MET 20  ? ? N  A ALA 21  ? ? 1.488 1.336 0.152  0.023 Y 
27  1 C  A ALA 21  ? ? O  A ALA 21  ? ? 1.362 1.229 0.133  0.019 N 
28  1 C  A ALA 21  ? ? N  A GLN 22  ? ? 1.505 1.336 0.169  0.023 Y 
29  1 C  A GLN 22  ? ? O  A GLN 22  ? ? 1.355 1.229 0.126  0.019 N 
30  1 C  A GLN 22  ? ? N  A MET 23  ? ? 1.575 1.336 0.239  0.023 Y 
31  1 C  A MET 23  ? ? N  A GLN 24  ? ? 1.547 1.336 0.211  0.023 Y 
32  1 C  A GLN 24  ? ? O  A GLN 24  ? ? 1.391 1.229 0.162  0.019 N 
33  1 C  A GLN 24  ? ? N  A LEU 25  ? ? 1.535 1.336 0.199  0.023 Y 
34  1 C  A LEU 25  ? ? N  A VAL 26  ? ? 1.545 1.336 0.209  0.023 Y 
35  1 C  A VAL 26  ? ? O  A VAL 26  ? ? 1.378 1.229 0.149  0.019 N 
36  1 C  A VAL 26  ? ? N  A GLN 27  ? ? 1.492 1.336 0.156  0.023 Y 
37  1 C  A SER 28  ? ? O  A SER 28  ? ? 1.438 1.229 0.209  0.019 N 
38  1 C  A GLY 29  ? ? O  A GLY 29  ? ? 1.351 1.232 0.119  0.016 N 
39  1 C  A THR 30  ? ? N  A GLU 31  ? ? 1.519 1.336 0.183  0.023 Y 
40  1 C  A GLU 31  ? ? N  A VAL 32  ? ? 1.486 1.336 0.150  0.023 Y 
41  1 C  A VAL 32  ? ? N  A LYS 33  ? ? 1.526 1.336 0.190  0.023 Y 
42  1 C  A LYS 33  ? ? O  A LYS 33  ? ? 1.361 1.229 0.132  0.019 N 
43  1 N  A LYS 34  ? ? CA A LYS 34  ? ? 1.630 1.459 0.171  0.020 N 
44  1 C  A LYS 34  ? ? O  A LYS 34  ? ? 1.356 1.229 0.127  0.019 N 
45  1 C  A LYS 34  ? ? N  A PRO 35  ? ? 1.502 1.338 0.164  0.019 Y 
46  1 C  A PRO 35  ? ? O  A PRO 35  ? ? 1.374 1.228 0.146  0.020 N 
47  1 C  A PRO 35  ? ? N  A GLY 36  ? ? 1.541 1.336 0.205  0.023 Y 
48  1 N  A GLY 36  ? ? CA A GLY 36  ? ? 1.308 1.456 -0.148 0.015 N 
49  1 C  A GLY 36  ? ? O  A GLY 36  ? ? 1.356 1.232 0.124  0.016 N 
50  1 C  A GLY 36  ? ? N  A GLU 37  ? ? 1.546 1.336 0.210  0.023 Y 
51  1 C  A GLU 37  ? ? O  A GLU 37  ? ? 1.427 1.229 0.198  0.019 N 
52  1 C  A GLU 37  ? ? N  A SER 38  ? ? 1.537 1.336 0.201  0.023 Y 
53  1 C  A SER 38  ? ? O  A SER 38  ? ? 1.387 1.229 0.158  0.019 N 
54  1 C  A SER 38  ? ? N  A LEU 39  ? ? 1.502 1.336 0.166  0.023 Y 
55  1 C  A LYS 40  ? ? O  A LYS 40  ? ? 1.365 1.229 0.136  0.019 N 
56  1 C  A LYS 40  ? ? N  A ILE 41  ? ? 1.545 1.336 0.209  0.023 Y 
57  1 N  A ILE 41  ? ? CA A ILE 41  ? ? 1.322 1.459 -0.137 0.020 N 
58  1 C  A ILE 41  ? ? O  A ILE 41  ? ? 1.357 1.229 0.128  0.019 N 
59  1 C  A ILE 41  ? ? N  A SER 42  ? ? 1.589 1.336 0.253  0.023 Y 
60  1 C  A SER 42  ? ? O  A SER 42  ? ? 1.358 1.229 0.129  0.019 N 
61  1 C  A SER 42  ? ? N  A CYS 43  ? ? 1.516 1.336 0.180  0.023 Y 
62  1 C  A CYS 43  ? ? O  A CYS 43  ? ? 1.345 1.229 0.116  0.019 N 
63  1 C  A CYS 43  ? ? N  A LYS 44  ? ? 1.544 1.336 0.208  0.023 Y 
64  1 C  A LYS 44  ? ? O  A LYS 44  ? ? 1.349 1.229 0.120  0.019 N 
65  1 C  A LYS 44  ? ? N  A GLY 45  ? ? 1.530 1.336 0.194  0.023 Y 
66  1 C  A GLY 45  ? ? N  A SER 46  ? ? 1.525 1.336 0.189  0.023 Y 
67  1 C  A SER 46  ? ? O  A SER 46  ? ? 1.358 1.229 0.129  0.019 N 
68  1 C  A SER 46  ? ? N  A GLY 47  ? ? 1.507 1.336 0.171  0.023 Y 
69  1 N  A GLY 47  ? ? CA A GLY 47  ? ? 1.565 1.456 0.109  0.015 N 
70  1 C  A GLY 47  ? ? O  A GLY 47  ? ? 1.374 1.232 0.142  0.016 N 
71  1 C  A GLY 47  ? ? N  A TYR 48  ? ? 1.491 1.336 0.155  0.023 Y 
72  1 C  A TYR 48  ? ? O  A TYR 48  ? ? 1.395 1.229 0.166  0.019 N 
73  1 C  A GLY 49  ? ? O  A GLY 49  ? ? 1.342 1.232 0.110  0.016 N 
74  1 C  A GLY 49  ? ? N  A PHE 50  ? ? 1.540 1.336 0.204  0.023 Y 
75  1 CA A PHE 50  ? ? C  A PHE 50  ? ? 1.759 1.525 0.234  0.026 N 
76  1 C  A PHE 50  ? ? O  A PHE 50  ? ? 1.378 1.229 0.149  0.019 N 
77  1 C  A PHE 50  ? ? N  A ILE 51  ? ? 1.629 1.336 0.293  0.023 Y 
78  1 N  A ILE 51  ? ? CA A ILE 51  ? ? 1.766 1.459 0.307  0.020 N 
79  1 C  A ILE 51  ? ? O  A ILE 51  ? ? 1.382 1.229 0.153  0.019 N 
80  1 C  A ILE 51  ? ? N  A THR 52  ? ? 1.576 1.336 0.240  0.023 Y 
81  1 C  A THR 52  ? ? O  A THR 52  ? ? 1.346 1.229 0.117  0.019 N 
82  1 C  A THR 52  ? ? N  A TYR 53  ? ? 1.639 1.336 0.303  0.023 Y 
83  1 C  A TYR 53  ? ? N  A TRP 54  ? ? 1.540 1.336 0.204  0.023 Y 
84  1 C  A TRP 54  ? ? N  A ILE 55  ? ? 1.562 1.336 0.226  0.023 Y 
85  1 C  A ILE 55  ? ? N  A GLY 56  ? ? 1.551 1.336 0.215  0.023 Y 
86  1 C  A TRP 57  ? ? N  A VAL 58  ? ? 1.493 1.336 0.157  0.023 Y 
87  1 C  A VAL 58  ? ? N  A ARG 59  ? ? 1.523 1.336 0.187  0.023 Y 
88  1 C  A ARG 59  ? ? O  A ARG 59  ? ? 1.357 1.229 0.128  0.019 N 
89  1 C  A ARG 59  ? ? N  A GLN 60  ? ? 1.522 1.336 0.186  0.023 Y 
90  1 C  A GLN 60  ? ? O  A GLN 60  ? ? 1.393 1.229 0.164  0.019 N 
91  1 C  A GLN 60  ? ? N  A MET 61  ? ? 1.510 1.336 0.174  0.023 Y 
92  1 C  A MET 61  ? ? N  A PRO 62  ? ? 1.452 1.338 0.114  0.019 Y 
93  1 C  A GLY 63  ? ? O  A GLY 63  ? ? 1.365 1.232 0.133  0.016 N 
94  1 C  A GLY 63  ? ? N  A LYS 64  ? ? 1.526 1.336 0.190  0.023 Y 
95  1 CA A LYS 64  ? ? C  A LYS 64  ? ? 1.733 1.525 0.208  0.026 N 
96  1 C  A LYS 64  ? ? O  A LYS 64  ? ? 1.483 1.229 0.254  0.019 N 
97  1 C  A LYS 64  ? ? N  A GLY 65  ? ? 1.476 1.336 0.140  0.023 Y 
98  1 CA A GLY 65  ? ? C  A GLY 65  ? ? 1.707 1.514 0.193  0.016 N 
99  1 C  A GLY 65  ? ? O  A GLY 65  ? ? 1.457 1.232 0.225  0.016 N 
100 1 C  A LEU 66  ? ? N  A GLU 67  ? ? 1.544 1.336 0.208  0.023 Y 
101 1 C  A GLU 67  ? ? O  A GLU 67  ? ? 1.345 1.229 0.116  0.019 N 
102 1 C  A GLU 67  ? ? N  A TRP 68  ? ? 1.546 1.336 0.210  0.023 Y 
103 1 C  A TRP 68  ? ? N  A MET 69  ? ? 1.536 1.336 0.200  0.023 Y 
104 1 C  A ILE 71  ? ? N  A ILE 72  ? ? 1.556 1.336 0.220  0.023 Y 
105 1 N  A ILE 72  ? ? CA A ILE 72  ? ? 1.332 1.459 -0.127 0.020 N 
106 1 C  A ILE 72  ? ? N  A TYR 73  ? ? 1.555 1.336 0.219  0.023 Y 
107 1 C  A TYR 73  ? ? N  A PRO 74  ? ? 1.554 1.338 0.216  0.019 Y 
108 1 N  A PRO 74  ? ? CA A PRO 74  ? ? 1.362 1.468 -0.106 0.017 N 
109 1 C  A PRO 74  ? ? O  A PRO 74  ? ? 1.419 1.228 0.191  0.020 N 
110 1 C  A GLY 75  ? ? N  A ASP 76  ? ? 1.578 1.336 0.242  0.023 Y 
111 1 CA A ASP 76  ? ? C  A ASP 76  ? ? 1.286 1.525 -0.239 0.026 N 
112 1 C  A ASP 76  ? ? O  A ASP 76  ? ? 1.377 1.229 0.148  0.019 N 
113 1 C  A ASP 76  ? ? N  A SER 77  ? ? 1.505 1.336 0.169  0.023 Y 
114 1 C  A SER 77  ? ? N  A GLU 78  ? ? 1.598 1.336 0.262  0.023 Y 
115 1 CA A GLU 78  ? ? C  A GLU 78  ? ? 1.783 1.525 0.258  0.026 N 
116 1 C  A GLU 78  ? ? O  A GLU 78  ? ? 1.520 1.229 0.291  0.019 N 
117 1 C  A THR 79  ? ? N  A ARG 80  ? ? 1.550 1.336 0.214  0.023 Y 
118 1 C  A ARG 80  ? ? N  A TYR 81  ? ? 1.535 1.336 0.199  0.023 Y 
119 1 C  A TYR 81  ? ? O  A TYR 81  ? ? 1.367 1.229 0.138  0.019 N 
120 1 C  A TYR 81  ? ? N  A SER 82  ? ? 1.544 1.336 0.208  0.023 Y 
121 1 C  A SER 82  ? ? N  A PRO 83  ? ? 1.511 1.338 0.173  0.019 Y 
122 1 C  A PRO 83  ? ? O  A PRO 83  ? ? 1.420 1.228 0.192  0.020 N 
123 1 C  A PRO 83  ? ? N  A SER 84  ? ? 1.540 1.336 0.204  0.023 Y 
124 1 C  A SER 84  ? ? O  A SER 84  ? ? 1.389 1.229 0.160  0.019 N 
125 1 C  A SER 84  ? ? N  A PHE 85  ? ? 1.546 1.336 0.210  0.023 Y 
126 1 C  A PHE 85  ? ? N  A GLN 86  ? ? 1.554 1.336 0.218  0.023 Y 
127 1 C  A GLN 86  ? ? O  A GLN 86  ? ? 1.460 1.229 0.231  0.019 N 
128 1 C  A GLY 87  ? ? N  A GLN 88  ? ? 1.573 1.336 0.237  0.023 Y 
129 1 C  A GLN 88  ? ? N  A VAL 89  ? ? 1.512 1.336 0.176  0.023 Y 
130 1 C  A VAL 89  ? ? N  A THR 90  ? ? 1.564 1.336 0.228  0.023 Y 
131 1 N  A THR 90  ? ? CA A THR 90  ? ? 1.308 1.459 -0.151 0.020 N 
132 1 C  A THR 90  ? ? N  A ILE 91  ? ? 1.568 1.336 0.232  0.023 Y 
133 1 N  A ILE 91  ? ? CA A ILE 91  ? ? 1.314 1.459 -0.145 0.020 N 
134 1 C  A ILE 91  ? ? N  A SER 92  ? ? 1.562 1.336 0.226  0.023 Y 
135 1 C  A SER 92  ? ? N  A ALA 93  ? ? 1.566 1.336 0.230  0.023 Y 
136 1 C  A ALA 93  ? ? N  A ASP 94  ? ? 1.550 1.336 0.214  0.023 Y 
137 1 C  A ASP 94  ? ? O  A ASP 94  ? ? 1.398 1.229 0.169  0.019 N 
138 1 C  A ASP 94  ? ? N  A LYS 95  ? ? 1.544 1.336 0.208  0.023 Y 
139 1 C  A LYS 95  ? ? O  A LYS 95  ? ? 1.387 1.229 0.158  0.019 N 
140 1 C  A LYS 95  ? ? N  A SER 96  ? ? 1.534 1.336 0.198  0.023 Y 
141 1 C  A SER 96  ? ? O  A SER 96  ? ? 1.410 1.229 0.181  0.019 N 
142 1 C  A SER 96  ? ? N  A ILE 97  ? ? 1.550 1.336 0.214  0.023 Y 
143 1 C  A ASN 98  ? ? N  A THR 99  ? ? 1.547 1.336 0.211  0.023 Y 
144 1 C  A THR 99  ? ? N  A ALA 100 ? ? 1.507 1.336 0.171  0.023 Y 
145 1 C  A ALA 100 ? ? N  A TYR 101 ? ? 1.527 1.336 0.191  0.023 Y 
146 1 C  A LEU 102 ? ? N  A GLN 103 ? ? 1.555 1.336 0.219  0.023 Y 
147 1 C  A GLN 103 ? ? O  A GLN 103 ? ? 1.383 1.229 0.154  0.019 N 
148 1 C  A GLN 103 ? ? N  A TRP 104 ? ? 1.503 1.336 0.167  0.023 Y 
149 1 C  A TRP 104 ? ? N  A SER 105 ? ? 1.606 1.336 0.270  0.023 Y 
150 1 N  A SER 105 ? ? CA A SER 105 ? ? 1.328 1.459 -0.131 0.020 N 
151 1 C  A SER 105 ? ? O  A SER 105 ? ? 1.092 1.229 -0.137 0.019 N 
152 1 C  A SER 105 ? ? N  A SER 106 ? ? 1.037 1.336 -0.299 0.023 Y 
153 1 C  A SER 106 ? ? O  A SER 106 ? ? 1.389 1.229 0.160  0.019 N 
154 1 C  A SER 106 ? ? N  A LEU 107 ? ? 1.571 1.336 0.235  0.023 Y 
155 1 C  A LEU 107 ? ? N  A LYS 108 ? ? 1.576 1.336 0.240  0.023 Y 
156 1 N  A LYS 108 ? ? CA A LYS 108 ? ? 1.318 1.459 -0.141 0.020 N 
157 1 C  A LYS 108 ? ? O  A LYS 108 ? ? 1.410 1.229 0.181  0.019 N 
158 1 C  A LYS 108 ? ? N  A ALA 109 ? ? 1.523 1.336 0.187  0.023 Y 
159 1 C  A ALA 109 ? ? O  A ALA 109 ? ? 1.406 1.229 0.177  0.019 N 
160 1 C  A ALA 109 ? ? N  A SER 110 ? ? 1.510 1.336 0.174  0.023 Y 
161 1 N  A SER 110 ? ? CA A SER 110 ? ? 1.579 1.459 0.120  0.020 N 
162 1 C  A SER 110 ? ? O  A SER 110 ? ? 1.385 1.229 0.156  0.019 N 
163 1 C  A SER 110 ? ? N  A ASP 111 ? ? 1.533 1.336 0.197  0.023 Y 
164 1 C  A ASP 111 ? ? N  A THR 112 ? ? 1.573 1.336 0.237  0.023 Y 
165 1 CA A THR 112 ? ? C  A THR 112 ? ? 1.688 1.525 0.163  0.026 N 
166 1 C  A THR 112 ? ? O  A THR 112 ? ? 1.429 1.229 0.200  0.019 N 
167 1 C  A ALA 113 ? ? O  A ALA 113 ? ? 1.409 1.229 0.180  0.019 N 
168 1 C  A ALA 113 ? ? N  A ILE 114 ? ? 1.481 1.336 0.145  0.023 Y 
169 1 C  A TYR 115 ? ? N  A TYR 116 ? ? 1.560 1.336 0.224  0.023 Y 
170 1 N  A TYR 116 ? ? CA A TYR 116 ? ? 1.327 1.459 -0.132 0.020 N 
171 1 C  A TYR 116 ? ? N  A CYS 117 ? ? 1.575 1.336 0.239  0.023 Y 
172 1 C  A CYS 117 ? ? O  A CYS 117 ? ? 1.345 1.229 0.116  0.019 N 
173 1 C  A CYS 117 ? ? N  A ALA 118 ? ? 1.520 1.336 0.184  0.023 Y 
174 1 C  A GLY 119 ? ? N  A GLY 120 ? ? 1.511 1.336 0.175  0.023 Y 
175 1 CA A SER 121 ? ? C  A SER 121 ? ? 1.353 1.525 -0.172 0.026 N 
176 1 C  A SER 121 ? ? O  A SER 121 ? ? 1.359 1.229 0.130  0.019 N 
177 1 C  A SER 121 ? ? N  A GLY 122 ? ? 1.580 1.336 0.244  0.023 Y 
178 1 CA A GLY 122 ? ? C  A GLY 122 ? ? 1.729 1.514 0.215  0.016 N 
179 1 C  A ILE 123 ? ? N  A SER 124 ? ? 1.570 1.336 0.234  0.023 Y 
180 1 C  A SER 124 ? ? O  A SER 124 ? ? 1.378 1.229 0.149  0.019 N 
181 1 C  A SER 124 ? ? N  A THR 125 ? ? 1.549 1.336 0.213  0.023 Y 
182 1 N  A THR 125 ? ? CA A THR 125 ? ? 1.333 1.459 -0.126 0.020 N 
183 1 C  A THR 125 ? ? O  A THR 125 ? ? 1.349 1.229 0.120  0.019 N 
184 1 C  A THR 125 ? ? N  A PRO 126 ? ? 1.581 1.338 0.243  0.019 Y 
185 1 C  A PRO 126 ? ? O  A PRO 126 ? ? 1.403 1.228 0.175  0.020 N 
186 1 C  A MET 127 ? ? O  A MET 127 ? ? 1.354 1.229 0.125  0.019 N 
187 1 C  A MET 127 ? ? N  A ASP 128 ? ? 1.591 1.336 0.255  0.023 Y 
188 1 C  A ASP 128 ? ? O  A ASP 128 ? ? 1.425 1.229 0.196  0.019 N 
189 1 C  A ASP 128 ? ? N  A VAL 129 ? ? 1.544 1.336 0.208  0.023 Y 
190 1 C  A VAL 129 ? ? N  A TRP 130 ? ? 1.567 1.336 0.231  0.023 Y 
191 1 C  A TRP 130 ? ? N  A GLY 131 ? ? 1.527 1.336 0.191  0.023 Y 
192 1 N  A GLY 131 ? ? CA A GLY 131 ? ? 1.332 1.456 -0.124 0.015 N 
193 1 CA A GLN 132 ? ? C  A GLN 132 ? ? 1.685 1.525 0.160  0.026 N 
194 1 C  A GLN 132 ? ? N  A GLY 133 ? ? 1.195 1.336 -0.141 0.023 Y 
195 1 C  A THR 134 ? ? O  A THR 134 ? ? 1.344 1.229 0.115  0.019 N 
196 1 C  A THR 134 ? ? N  A THR 135 ? ? 1.519 1.336 0.183  0.023 Y 
197 1 C  A THR 135 ? ? N  A VAL 136 ? ? 1.515 1.336 0.179  0.023 Y 
198 1 C  A VAL 136 ? ? O  A VAL 136 ? ? 1.347 1.229 0.118  0.019 N 
199 1 C  A VAL 136 ? ? N  A THR 137 ? ? 1.553 1.336 0.217  0.023 Y 
200 1 C  A THR 137 ? ? N  A VAL 138 ? ? 1.507 1.336 0.171  0.023 Y 
201 1 C  A VAL 138 ? ? N  A SER 139 ? ? 1.554 1.336 0.218  0.023 Y 
202 1 N  A SER 139 ? ? CA A SER 139 ? ? 1.336 1.459 -0.123 0.020 N 
203 1 C  A SER 139 ? ? O  A SER 139 ? ? 1.375 1.229 0.146  0.019 N 
204 1 C  A SER 140 ? ? N  A GLY 141 ? ? 1.508 1.336 0.172  0.023 Y 
205 1 CA A GLY 141 ? ? C  A GLY 141 ? ? 1.649 1.514 0.135  0.016 N 
206 1 C  A GLY 141 ? ? O  A GLY 141 ? ? 1.395 1.232 0.163  0.016 N 
207 1 C  A SER 142 ? ? N  A GLY 143 ? ? 1.520 1.336 0.184  0.023 Y 
208 1 C  A GLY 145 ? ? N  A GLY 146 ? ? 1.474 1.336 0.138  0.023 Y 
209 1 C  A GLY 146 ? ? O  A GLY 146 ? ? 1.363 1.232 0.131  0.016 N 
210 1 C  A GLY 146 ? ? N  A SER 147 ? ? 1.502 1.336 0.166  0.023 Y 
211 1 C  A SER 147 ? ? O  A SER 147 ? ? 1.375 1.229 0.146  0.019 N 
212 1 C  A SER 147 ? ? N  A ASP 148 ? ? 1.546 1.336 0.210  0.023 Y 
213 1 CA A ASP 148 ? ? C  A ASP 148 ? ? 1.780 1.525 0.255  0.026 N 
214 1 C  A ILE 149 ? ? N  A GLN 150 ? ? 1.571 1.336 0.235  0.023 Y 
215 1 C  A GLN 150 ? ? N  A LEU 151 ? ? 1.593 1.336 0.257  0.023 Y 
216 1 C  A LEU 151 ? ? N  A THR 152 ? ? 1.189 1.336 -0.147 0.023 Y 
217 1 CA A THR 152 ? ? C  A THR 152 ? ? 1.882 1.525 0.357  0.026 N 
218 1 C  A THR 152 ? ? O  A THR 152 ? ? 1.357 1.229 0.128  0.019 N 
219 1 C  A GLN 153 ? ? O  A GLN 153 ? ? 1.354 1.229 0.125  0.019 N 
220 1 C  A GLN 153 ? ? N  A SER 154 ? ? 1.585 1.336 0.249  0.023 Y 
221 1 C  A SER 154 ? ? N  A PRO 155 ? ? 1.536 1.338 0.198  0.019 Y 
222 1 C  A PRO 155 ? ? N  A ASP 156 ? ? 1.597 1.336 0.261  0.023 Y 
223 1 C  A ASP 156 ? ? O  A ASP 156 ? ? 1.344 1.229 0.115  0.019 N 
224 1 C  A ASP 156 ? ? N  A SER 157 ? ? 1.596 1.336 0.260  0.023 Y 
225 1 C  A SER 157 ? ? N  A LEU 158 ? ? 1.528 1.336 0.192  0.023 Y 
226 1 C  A LEU 158 ? ? O  A LEU 158 ? ? 1.395 1.229 0.166  0.019 N 
227 1 C  A LEU 158 ? ? N  A ALA 159 ? ? 1.516 1.336 0.180  0.023 Y 
228 1 C  A ALA 159 ? ? O  A ALA 159 ? ? 1.389 1.229 0.160  0.019 N 
229 1 C  A ALA 159 ? ? N  A VAL 160 ? ? 1.488 1.336 0.152  0.023 Y 
230 1 C  A VAL 160 ? ? O  A VAL 160 ? ? 1.435 1.229 0.206  0.019 N 
231 1 C  A VAL 160 ? ? N  A SER 161 ? ? 1.495 1.336 0.159  0.023 Y 
232 1 N  A SER 161 ? ? CA A SER 161 ? ? 1.587 1.459 0.128  0.020 N 
233 1 C  A SER 161 ? ? O  A SER 161 ? ? 1.350 1.229 0.121  0.019 N 
234 1 C  A SER 161 ? ? N  A LEU 162 ? ? 1.494 1.336 0.158  0.023 Y 
235 1 C  A LEU 162 ? ? O  A LEU 162 ? ? 1.392 1.229 0.163  0.019 N 
236 1 C  A LEU 162 ? ? N  A GLY 163 ? ? 1.533 1.336 0.197  0.023 Y 
237 1 N  A GLY 163 ? ? CA A GLY 163 ? ? 1.290 1.456 -0.166 0.015 N 
238 1 C  A GLY 163 ? ? O  A GLY 163 ? ? 1.354 1.232 0.122  0.016 N 
239 1 C  A GLY 163 ? ? N  A GLU 164 ? ? 1.538 1.336 0.202  0.023 Y 
240 1 C  A GLU 164 ? ? O  A GLU 164 ? ? 1.398 1.229 0.169  0.019 N 
241 1 C  A GLU 164 ? ? N  A ARG 165 ? ? 1.536 1.336 0.200  0.023 Y 
242 1 C  A ARG 165 ? ? O  A ARG 165 ? ? 1.346 1.229 0.117  0.019 N 
243 1 C  A ARG 165 ? ? N  A ALA 166 ? ? 1.521 1.336 0.185  0.023 Y 
244 1 C  A ALA 166 ? ? O  A ALA 166 ? ? 1.344 1.229 0.115  0.019 N 
245 1 C  A ALA 166 ? ? N  A THR 167 ? ? 1.534 1.336 0.198  0.023 Y 
246 1 C  A THR 167 ? ? N  A ILE 168 ? ? 1.563 1.336 0.227  0.023 Y 
247 1 N  A ILE 168 ? ? CA A ILE 168 ? ? 1.332 1.459 -0.127 0.020 N 
248 1 C  A ILE 168 ? ? N  A ASN 169 ? ? 1.575 1.336 0.239  0.023 Y 
249 1 C  A ASN 169 ? ? N  A CYS 170 ? ? 1.553 1.336 0.217  0.023 Y 
250 1 N  A CYS 170 ? ? CA A CYS 170 ? ? 1.330 1.459 -0.129 0.020 N 
251 1 C  A CYS 170 ? ? N  A LYS 171 ? ? 1.530 1.336 0.194  0.023 Y 
252 1 C  A LYS 171 ? ? N  A SER 172 ? ? 1.541 1.336 0.205  0.023 Y 
253 1 C  A SER 172 ? ? N  A SER 173 ? ? 1.518 1.336 0.182  0.023 Y 
254 1 C  A SER 173 ? ? O  A SER 173 ? ? 1.464 1.229 0.235  0.019 N 
255 1 C  A SER 173 ? ? N  A GLN 174 ? ? 1.480 1.336 0.144  0.023 Y 
256 1 C  A GLN 174 ? ? N  A SER 175 ? ? 1.579 1.336 0.243  0.023 Y 
257 1 C  A SER 175 ? ? N  A VAL 176 ? ? 1.542 1.336 0.206  0.023 Y 
258 1 C  A VAL 176 ? ? N  A LEU 177 ? ? 1.594 1.336 0.258  0.023 Y 
259 1 C  A LEU 177 ? ? N  A TYR 178 ? ? 1.544 1.336 0.208  0.023 Y 
260 1 C  A TYR 178 ? ? N  A SER 179 ? ? 1.483 1.336 0.147  0.023 Y 
261 1 C  A SER 179 ? ? O  A SER 179 ? ? 1.347 1.229 0.118  0.019 N 
262 1 C  A SER 179 ? ? N  A SER 180 ? ? 1.638 1.336 0.302  0.023 Y 
263 1 CA A SER 180 ? ? C  A SER 180 ? ? 1.712 1.525 0.187  0.026 N 
264 1 C  A ILE 181 ? ? O  A ILE 181 ? ? 1.359 1.229 0.130  0.019 N 
265 1 C  A ILE 181 ? ? N  A ASN 182 ? ? 1.636 1.336 0.300  0.023 Y 
266 1 C  A ASN 182 ? ? O  A ASN 182 ? ? 1.406 1.229 0.177  0.019 N 
267 1 C  A ASN 182 ? ? N  A LYS 183 ? ? 1.529 1.336 0.193  0.023 Y 
268 1 C  A LYS 183 ? ? O  A LYS 183 ? ? 1.379 1.229 0.150  0.019 N 
269 1 C  A LYS 183 ? ? N  A ASN 184 ? ? 1.545 1.336 0.209  0.023 Y 
270 1 C  A ASN 184 ? ? O  A ASN 184 ? ? 1.407 1.229 0.178  0.019 N 
271 1 C  A ASN 184 ? ? N  A TYR 185 ? ? 1.519 1.336 0.183  0.023 Y 
272 1 C  A TYR 185 ? ? N  A LEU 186 ? ? 1.552 1.336 0.216  0.023 Y 
273 1 C  A LEU 186 ? ? O  A LEU 186 ? ? 1.352 1.229 0.123  0.019 N 
274 1 C  A LEU 186 ? ? N  A ALA 187 ? ? 1.557 1.336 0.221  0.023 Y 
275 1 C  A TRP 188 ? ? N  A TYR 189 ? ? 1.548 1.336 0.212  0.023 Y 
276 1 N  A TYR 189 ? ? CA A TYR 189 ? ? 1.328 1.459 -0.131 0.020 N 
277 1 C  A TYR 189 ? ? N  A GLN 190 ? ? 1.540 1.336 0.204  0.023 Y 
278 1 N  A GLN 190 ? ? CA A GLN 190 ? ? 1.300 1.459 -0.159 0.020 N 
279 1 C  A GLN 190 ? ? O  A GLN 190 ? ? 1.376 1.229 0.147  0.019 N 
280 1 C  A GLN 190 ? ? N  A GLN 191 ? ? 1.538 1.336 0.202  0.023 Y 
281 1 C  A GLN 191 ? ? O  A GLN 191 ? ? 1.411 1.229 0.182  0.019 N 
282 1 C  A GLN 191 ? ? N  A LYS 192 ? ? 1.494 1.336 0.158  0.023 Y 
283 1 C  A PRO 193 ? ? O  A PRO 193 ? ? 1.370 1.228 0.142  0.020 N 
284 1 C  A PRO 193 ? ? N  A GLY 194 ? ? 1.519 1.336 0.183  0.023 Y 
285 1 C  A GLY 194 ? ? O  A GLY 194 ? ? 1.366 1.232 0.134  0.016 N 
286 1 C  A GLY 194 ? ? N  A GLN 195 ? ? 1.524 1.336 0.188  0.023 Y 
287 1 C  A GLN 195 ? ? O  A GLN 195 ? ? 1.429 1.229 0.200  0.019 N 
288 1 C  A GLN 195 ? ? N  A PRO 196 ? ? 1.495 1.338 0.157  0.019 Y 
289 1 C  A PRO 196 ? ? O  A PRO 196 ? ? 1.386 1.228 0.158  0.020 N 
290 1 C  A PRO 196 ? ? N  A PRO 197 ? ? 1.499 1.338 0.161  0.019 Y 
291 1 C  A PRO 197 ? ? N  A LYS 198 ? ? 1.551 1.336 0.215  0.023 Y 
292 1 C  A LYS 198 ? ? N  A LEU 199 ? ? 1.512 1.336 0.176  0.023 Y 
293 1 C  A LEU 199 ? ? N  A LEU 200 ? ? 1.542 1.336 0.206  0.023 Y 
294 1 C  A LEU 200 ? ? N  A ILE 201 ? ? 1.487 1.336 0.151  0.023 Y 
295 1 C  A ILE 201 ? ? N  A TYR 202 ? ? 1.494 1.336 0.158  0.023 Y 
296 1 C  A TYR 202 ? ? N  A TRP 203 ? ? 1.549 1.336 0.213  0.023 Y 
297 1 C  A TRP 203 ? ? O  A TRP 203 ? ? 1.352 1.229 0.123  0.019 N 
298 1 C  A TRP 203 ? ? N  A ALA 204 ? ? 1.557 1.336 0.221  0.023 Y 
299 1 C  A ALA 204 ? ? O  A ALA 204 ? ? 1.435 1.229 0.206  0.019 N 
300 1 C  A SER 205 ? ? O  A SER 205 ? ? 1.395 1.229 0.166  0.019 N 
301 1 C  A SER 205 ? ? N  A THR 206 ? ? 1.558 1.336 0.222  0.023 Y 
302 1 C  A THR 206 ? ? N  A ARG 207 ? ? 1.578 1.336 0.242  0.023 Y 
303 1 C  A ARG 207 ? ? N  A GLU 208 ? ? 1.602 1.336 0.266  0.023 Y 
304 1 C  A GLU 208 ? ? O  A GLU 208 ? ? 1.350 1.229 0.121  0.019 N 
305 1 C  A GLU 208 ? ? N  A SER 209 ? ? 1.517 1.336 0.181  0.023 Y 
306 1 C  A SER 209 ? ? O  A SER 209 ? ? 1.409 1.229 0.180  0.019 N 
307 1 C  A GLY 210 ? ? O  A GLY 210 ? ? 1.371 1.232 0.139  0.016 N 
308 1 C  A GLY 210 ? ? N  A VAL 211 ? ? 1.518 1.336 0.182  0.023 Y 
309 1 C  A VAL 211 ? ? O  A VAL 211 ? ? 1.377 1.229 0.148  0.019 N 
310 1 C  A VAL 211 ? ? N  A PRO 212 ? ? 1.518 1.338 0.180  0.019 Y 
311 1 C  A PRO 212 ? ? N  A ASP 213 ? ? 1.540 1.336 0.204  0.023 Y 
312 1 C  A ASP 213 ? ? N  A ARG 214 ? ? 1.569 1.336 0.233  0.023 Y 
313 1 C  A ARG 214 ? ? N  A PHE 215 ? ? 1.567 1.336 0.231  0.023 Y 
314 1 C  A PHE 215 ? ? N  A SER 216 ? ? 1.506 1.336 0.170  0.023 Y 
315 1 C  A SER 216 ? ? N  A GLY 217 ? ? 1.514 1.336 0.178  0.023 Y 
316 1 C  A SER 218 ? ? N  A GLY 219 ? ? 1.547 1.336 0.211  0.023 Y 
317 1 C  A SER 220 ? ? N  A GLY 221 ? ? 1.578 1.336 0.242  0.023 Y 
318 1 C  A GLY 221 ? ? N  A THR 222 ? ? 1.561 1.336 0.225  0.023 Y 
319 1 C  A THR 222 ? ? O  A THR 222 ? ? 1.362 1.229 0.133  0.019 N 
320 1 C  A THR 222 ? ? N  A ASP 223 ? ? 1.571 1.336 0.235  0.023 Y 
321 1 C  A ASP 223 ? ? N  A PHE 224 ? ? 1.500 1.336 0.164  0.023 Y 
322 1 C  A PHE 224 ? ? N  A THR 225 ? ? 1.523 1.336 0.187  0.023 Y 
323 1 C  A THR 225 ? ? N  A LEU 226 ? ? 1.557 1.336 0.221  0.023 Y 
324 1 C  A LEU 226 ? ? N  A THR 227 ? ? 1.584 1.336 0.248  0.023 Y 
325 1 C  A ILE 228 ? ? N  A SER 229 ? ? 1.605 1.336 0.269  0.023 Y 
326 1 C  A SER 229 ? ? O  A SER 229 ? ? 1.075 1.229 -0.154 0.019 N 
327 1 C  A SER 229 ? ? N  A SER 230 ? ? 1.113 1.336 -0.223 0.023 Y 
328 1 C  A SER 230 ? ? O  A SER 230 ? ? 1.395 1.229 0.166  0.019 N 
329 1 C  A SER 230 ? ? N  A LEU 231 ? ? 1.554 1.336 0.218  0.023 Y 
330 1 C  A LEU 231 ? ? N  A GLN 232 ? ? 1.562 1.336 0.226  0.023 Y 
331 1 C  A GLN 232 ? ? O  A GLN 232 ? ? 1.400 1.229 0.171  0.019 N 
332 1 C  A GLN 232 ? ? N  A ALA 233 ? ? 1.505 1.336 0.169  0.023 Y 
333 1 C  A ALA 233 ? ? O  A ALA 233 ? ? 1.386 1.229 0.157  0.019 N 
334 1 C  A ALA 233 ? ? N  A GLU 234 ? ? 1.528 1.336 0.192  0.023 Y 
335 1 C  A GLU 234 ? ? O  A GLU 234 ? ? 1.385 1.229 0.156  0.019 N 
336 1 C  A GLU 234 ? ? N  A ASP 235 ? ? 1.526 1.336 0.190  0.023 Y 
337 1 C  A ASP 235 ? ? N  A VAL 236 ? ? 1.583 1.336 0.247  0.023 Y 
338 1 C  A VAL 236 ? ? O  A VAL 236 ? ? 1.104 1.229 -0.125 0.019 N 
339 1 C  A VAL 236 ? ? N  A ALA 237 ? ? 1.147 1.336 -0.189 0.023 Y 
340 1 C  A ALA 237 ? ? O  A ALA 237 ? ? 1.373 1.229 0.144  0.019 N 
341 1 C  A ALA 237 ? ? N  A VAL 238 ? ? 1.518 1.336 0.182  0.023 Y 
342 1 C  A VAL 238 ? ? O  A VAL 238 ? ? 1.113 1.229 -0.116 0.019 N 
343 1 N  A TYR 239 ? ? CA A TYR 239 ? ? 1.590 1.459 0.131  0.020 N 
344 1 C  A TYR 239 ? ? O  A TYR 239 ? ? 1.353 1.229 0.124  0.019 N 
345 1 C  A TYR 239 ? ? N  A TYR 240 ? ? 1.571 1.336 0.235  0.023 Y 
346 1 C  A TYR 240 ? ? N  A CYS 241 ? ? 1.554 1.336 0.218  0.023 Y 
347 1 C  A CYS 241 ? ? N  A GLN 242 ? ? 1.548 1.336 0.212  0.023 Y 
348 1 C  A GLN 243 ? ? N  A TYR 244 ? ? 1.527 1.336 0.191  0.023 Y 
349 1 C  A TYR 244 ? ? O  A TYR 244 ? ? 1.368 1.229 0.139  0.019 N 
350 1 C  A TYR 244 ? ? N  A TYR 245 ? ? 1.522 1.336 0.186  0.023 Y 
351 1 C  A TYR 245 ? ? N  A SER 246 ? ? 1.527 1.336 0.191  0.023 Y 
352 1 C  A THR 247 ? ? O  A THR 247 ? ? 1.350 1.229 0.121  0.019 N 
353 1 C  A THR 247 ? ? N  A PRO 248 ? ? 1.555 1.338 0.217  0.019 Y 
354 1 C  A PRO 248 ? ? O  A PRO 248 ? ? 1.360 1.228 0.132  0.020 N 
355 1 C  A PRO 248 ? ? N  A TYR 249 ? ? 1.571 1.336 0.235  0.023 Y 
356 1 C  A TYR 249 ? ? N  A THR 250 ? ? 1.549 1.336 0.213  0.023 Y 
357 1 C  A THR 250 ? ? N  A PHE 251 ? ? 1.495 1.336 0.159  0.023 Y 
358 1 C  A PHE 251 ? ? N  A GLY 252 ? ? 1.510 1.336 0.174  0.023 Y 
359 1 CA A GLY 252 ? ? C  A GLY 252 ? ? 1.631 1.514 0.117  0.016 N 
360 1 C  A GLY 252 ? ? O  A GLY 252 ? ? 1.371 1.232 0.139  0.016 N 
361 1 C  A GLN 253 ? ? O  A GLN 253 ? ? 1.368 1.229 0.139  0.019 N 
362 1 C  A GLN 253 ? ? N  A GLY 254 ? ? 1.512 1.336 0.176  0.023 Y 
363 1 C  A GLY 254 ? ? O  A GLY 254 ? ? 1.407 1.232 0.175  0.016 N 
364 1 C  A GLY 254 ? ? N  A THR 255 ? ? 1.487 1.336 0.151  0.023 Y 
365 1 C  A THR 255 ? ? O  A THR 255 ? ? 1.367 1.229 0.138  0.019 N 
366 1 C  A THR 255 ? ? N  A LYS 256 ? ? 1.505 1.336 0.169  0.023 Y 
367 1 N  A LYS 256 ? ? CA A LYS 256 ? ? 1.715 1.459 0.256  0.020 N 
368 1 C  A LYS 256 ? ? O  A LYS 256 ? ? 1.369 1.229 0.140  0.019 N 
369 1 C  A LYS 256 ? ? N  A VAL 257 ? ? 1.527 1.336 0.191  0.023 Y 
370 1 C  A VAL 257 ? ? N  A GLU 258 ? ? 1.513 1.336 0.177  0.023 Y 
371 1 C  A GLU 258 ? ? O  A GLU 258 ? ? 1.374 1.229 0.145  0.019 N 
372 1 C  A GLU 258 ? ? N  A ILE 259 ? ? 1.508 1.336 0.172  0.023 Y 
373 1 C  A LYS 260 ? ? O  A LYS 260 ? ? 1.380 1.229 0.151  0.019 N 
374 1 N  A HIS 262 ? ? CA A HIS 262 ? ? 1.659 1.459 0.200  0.020 N 
375 1 C  A HIS 262 ? ? N  A HIS 263 ? ? 1.493 1.336 0.157  0.023 Y 
376 1 CA A HIS 263 ? ? C  A HIS 263 ? ? 1.797 1.525 0.272  0.026 N 
377 1 C  A HIS 263 ? ? O  A HIS 263 ? ? 1.376 1.229 0.147  0.019 N 
378 1 N  A HIS 265 ? ? CA A HIS 265 ? ? 1.638 1.459 0.179  0.020 N 
379 1 CA A HIS 265 ? ? C  A HIS 265 ? ? 1.725 1.525 0.200  0.026 N 
380 1 C  A HIS 265 ? ? O  A HIS 265 ? ? 1.346 1.229 0.117  0.019 N 
381 1 CA A HIS 266 ? ? C  A HIS 266 ? ? 1.695 1.525 0.170  0.026 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1   1 O  A LEU 3   ? ? C  A LEU 3   ? ? N  A LEU 4   ? ? 133.91 122.70 11.21  1.60 Y 
2   1 CA A LEU 4   ? ? C  A LEU 4   ? ? O  A LEU 4   ? ? 103.93 120.10 -16.17 2.10 N 
3   1 O  A LEU 4   ? ? C  A LEU 4   ? ? N  A PRO 5   ? ? 134.55 121.10 13.45  1.90 Y 
4   1 O  A PRO 5   ? ? C  A PRO 5   ? ? N  A THR 6   ? ? 135.77 122.70 13.07  1.60 Y 
5   1 O  A THR 6   ? ? C  A THR 6   ? ? N  A ALA 7   ? ? 133.21 122.70 10.51  1.60 Y 
6   1 O  A ALA 7   ? ? C  A ALA 7   ? ? N  A ALA 8   ? ? 135.44 122.70 12.74  1.60 Y 
7   1 O  A ALA 8   ? ? C  A ALA 8   ? ? N  A ALA 9   ? ? 137.20 122.70 14.50  1.60 Y 
8   1 O  A ALA 9   ? ? C  A ALA 9   ? ? N  A GLY 10  ? ? 134.62 123.20 11.42  1.70 Y 
9   1 O  A GLY 10  ? ? C  A GLY 10  ? ? N  A LEU 11  ? ? 134.26 122.70 11.56  1.60 Y 
10  1 O  A LEU 11  ? ? C  A LEU 11  ? ? N  A LEU 12  ? ? 136.52 122.70 13.82  1.60 Y 
11  1 O  A LEU 12  ? ? C  A LEU 12  ? ? N  A LEU 13  ? ? 135.48 122.70 12.78  1.60 Y 
12  1 O  A LEU 13  ? ? C  A LEU 13  ? ? N  A LEU 14  ? ? 134.52 122.70 11.82  1.60 Y 
13  1 O  A LEU 14  ? ? C  A LEU 14  ? ? N  A ALA 15  ? ? 135.87 122.70 13.17  1.60 Y 
14  1 O  A ALA 16  ? ? C  A ALA 16  ? ? N  A GLN 17  ? ? 135.96 122.70 13.26  1.60 Y 
15  1 CA A GLN 17  ? ? C  A GLN 17  ? ? N  A PRO 18  ? ? 83.06  117.10 -34.04 2.80 Y 
16  1 C  A GLN 17  ? ? N  A PRO 18  ? ? CA A PRO 18  ? ? 102.08 127.00 -24.92 2.40 Y 
17  1 C  A GLN 17  ? ? N  A PRO 18  ? ? CD A PRO 18  ? ? 136.90 120.60 16.30  2.20 Y 
18  1 CA A PRO 18  ? ? N  A PRO 18  ? ? CD A PRO 18  ? ? 92.15  111.50 -19.35 1.40 N 
19  1 N  A PRO 18  ? ? CA A PRO 18  ? ? C  A PRO 18  ? ? 90.90  112.10 -21.20 2.60 N 
20  1 O  A PRO 18  ? ? C  A PRO 18  ? ? N  A ALA 19  ? ? 133.28 122.70 10.58  1.60 Y 
21  1 N  A GLN 22  ? ? CA A GLN 22  ? ? C  A GLN 22  ? ? 77.65  111.00 -33.35 2.70 N 
22  1 CA A GLN 22  ? ? C  A GLN 22  ? ? O  A GLN 22  ? ? 104.03 120.10 -16.07 2.10 N 
23  1 C  A GLN 22  ? ? N  A MET 23  ? ? CA A MET 23  ? ? 99.20  121.70 -22.50 2.50 Y 
24  1 N  A VAL 26  ? ? CA A VAL 26  ? ? C  A VAL 26  ? ? 138.63 111.00 27.63  2.70 N 
25  1 CA A VAL 26  ? ? C  A VAL 26  ? ? O  A VAL 26  ? ? 106.90 120.10 -13.20 2.10 N 
26  1 O  A VAL 26  ? ? C  A VAL 26  ? ? N  A GLN 27  ? ? 132.96 122.70 10.26  1.60 Y 
27  1 O  A GLN 27  ? ? C  A GLN 27  ? ? N  A SER 28  ? ? 108.79 122.70 -13.91 1.60 Y 
28  1 N  A SER 28  ? ? CA A SER 28  ? ? C  A SER 28  ? ? 79.25  111.00 -31.75 2.70 N 
29  1 O  A GLU 31  ? ? C  A GLU 31  ? ? N  A VAL 32  ? ? 134.41 122.70 11.71  1.60 Y 
30  1 O  A LYS 33  ? ? C  A LYS 33  ? ? N  A LYS 34  ? ? 133.48 122.70 10.78  1.60 Y 
31  1 O  A SER 46  ? ? C  A SER 46  ? ? N  A GLY 47  ? ? 135.87 123.20 12.67  1.70 Y 
32  1 C  A GLY 47  ? ? N  A TYR 48  ? ? CA A TYR 48  ? ? 105.44 121.70 -16.26 2.50 Y 
33  1 N  A TYR 48  ? ? CA A TYR 48  ? ? CB A TYR 48  ? ? 121.91 110.60 11.31  1.80 N 
34  1 N  A TYR 48  ? ? CA A TYR 48  ? ? C  A TYR 48  ? ? 66.56  111.00 -44.44 2.70 N 
35  1 N  A GLY 49  ? ? CA A GLY 49  ? ? C  A GLY 49  ? ? 95.36  113.10 -17.74 2.50 N 
36  1 N  A PHE 50  ? ? CA A PHE 50  ? ? C  A PHE 50  ? ? 87.93  111.00 -23.07 2.70 N 
37  1 C  A PHE 50  ? ? N  A ILE 51  ? ? CA A ILE 51  ? ? 76.17  121.70 -45.53 2.50 Y 
38  1 CB A ILE 51  ? ? CA A ILE 51  ? ? C  A ILE 51  ? ? 98.31  111.60 -13.29 2.00 N 
39  1 N  A ILE 51  ? ? CA A ILE 51  ? ? C  A ILE 51  ? ? 127.44 111.00 16.44  2.70 N 
40  1 N  A THR 52  ? ? CA A THR 52  ? ? C  A THR 52  ? ? 79.62  111.00 -31.38 2.70 N 
41  1 O  A TYR 53  ? ? C  A TYR 53  ? ? N  A TRP 54  ? ? 133.44 122.70 10.74  1.60 Y 
42  1 O  A TRP 54  ? ? C  A TRP 54  ? ? N  A ILE 55  ? ? 132.86 122.70 10.16  1.60 Y 
43  1 CA A PRO 62  ? ? C  A PRO 62  ? ? O  A PRO 62  ? ? 67.21  120.20 -52.99 2.40 N 
44  1 CA A PRO 62  ? ? C  A PRO 62  ? ? N  A GLY 63  ? ? 135.77 116.20 19.57  2.00 Y 
45  1 O  A PRO 62  ? ? C  A PRO 62  ? ? N  A GLY 63  ? ? 70.81  123.20 -52.39 1.70 Y 
46  1 C  A PRO 62  ? ? N  A GLY 63  ? ? CA A GLY 63  ? ? 156.88 122.30 34.58  2.10 Y 
47  1 C  A LYS 64  ? ? N  A GLY 65  ? ? CA A GLY 65  ? ? 103.15 122.30 -19.15 2.10 Y 
48  1 CA A LEU 66  ? ? C  A LEU 66  ? ? O  A LEU 66  ? ? 106.25 120.10 -13.85 2.10 N 
49  1 O  A LEU 66  ? ? C  A LEU 66  ? ? N  A GLU 67  ? ? 136.69 122.70 13.99  1.60 Y 
50  1 O  A MET 69  ? ? C  A MET 69  ? ? N  A GLY 70  ? ? 112.23 123.20 -10.97 1.70 Y 
51  1 O  A ILE 72  ? ? C  A ILE 72  ? ? N  A TYR 73  ? ? 133.76 122.70 11.06  1.60 Y 
52  1 O  A TYR 73  ? ? C  A TYR 73  ? ? N  A PRO 74  ? ? 133.73 121.10 12.63  1.90 Y 
53  1 CA A PRO 74  ? ? C  A PRO 74  ? ? N  A GLY 75  ? ? 103.43 116.20 -12.77 2.00 Y 
54  1 CA A GLY 75  ? ? C  A GLY 75  ? ? O  A GLY 75  ? ? 104.54 120.60 -16.06 1.80 N 
55  1 N  A ASP 76  ? ? CA A ASP 76  ? ? C  A ASP 76  ? ? 92.75  111.00 -18.25 2.70 N 
56  1 CA A ASP 76  ? ? C  A ASP 76  ? ? O  A ASP 76  ? ? 91.91  120.10 -28.19 2.10 N 
57  1 O  A ASP 76  ? ? C  A ASP 76  ? ? N  A SER 77  ? ? 135.83 122.70 13.13  1.60 Y 
58  1 C  A ASP 76  ? ? N  A SER 77  ? ? CA A SER 77  ? ? 143.28 121.70 21.58  2.50 Y 
59  1 CA A GLU 78  ? ? C  A GLU 78  ? ? O  A GLU 78  ? ? 133.15 120.10 13.05  2.10 N 
60  1 CA A GLU 78  ? ? C  A GLU 78  ? ? N  A THR 79  ? ? 96.87  117.20 -20.33 2.20 Y 
61  1 O  A THR 79  ? ? C  A THR 79  ? ? N  A ARG 80  ? ? 133.99 122.70 11.29  1.60 Y 
62  1 O  A ARG 80  ? ? C  A ARG 80  ? ? N  A TYR 81  ? ? 132.64 122.70 9.94   1.60 Y 
63  1 O  A TYR 81  ? ? C  A TYR 81  ? ? N  A SER 82  ? ? 132.97 122.70 10.27  1.60 Y 
64  1 O  A SER 82  ? ? C  A SER 82  ? ? N  A PRO 83  ? ? 135.64 121.10 14.54  1.90 Y 
65  1 CA A PHE 85  ? ? C  A PHE 85  ? ? O  A PHE 85  ? ? 107.06 120.10 -13.04 2.10 N 
66  1 O  A PHE 85  ? ? C  A PHE 85  ? ? N  A GLN 86  ? ? 133.94 122.70 11.24  1.60 Y 
67  1 CA A GLY 87  ? ? C  A GLY 87  ? ? O  A GLY 87  ? ? 104.33 120.60 -16.27 1.80 N 
68  1 O  A GLN 88  ? ? C  A GLN 88  ? ? N  A VAL 89  ? ? 133.55 122.70 10.85  1.60 Y 
69  1 O  A VAL 89  ? ? C  A VAL 89  ? ? N  A THR 90  ? ? 133.47 122.70 10.77  1.60 Y 
70  1 O  A ALA 93  ? ? C  A ALA 93  ? ? N  A ASP 94  ? ? 135.89 122.70 13.19  1.60 Y 
71  1 O  A ASP 94  ? ? C  A ASP 94  ? ? N  A LYS 95  ? ? 134.14 122.70 11.44  1.60 Y 
72  1 C  A LYS 95  ? ? N  A SER 96  ? ? CA A SER 96  ? ? 106.52 121.70 -15.18 2.50 Y 
73  1 O  A ILE 97  ? ? C  A ILE 97  ? ? N  A ASN 98  ? ? 111.91 122.70 -10.79 1.60 Y 
74  1 O  A ASN 98  ? ? C  A ASN 98  ? ? N  A THR 99  ? ? 133.15 122.70 10.45  1.60 Y 
75  1 O  A THR 99  ? ? C  A THR 99  ? ? N  A ALA 100 ? ? 135.52 122.70 12.82  1.60 Y 
76  1 O  A ALA 100 ? ? C  A ALA 100 ? ? N  A TYR 101 ? ? 134.36 122.70 11.66  1.60 Y 
77  1 CA A SER 105 ? ? C  A SER 105 ? ? O  A SER 105 ? ? 134.26 120.10 14.16  2.10 N 
78  1 O  A SER 105 ? ? C  A SER 105 ? ? N  A SER 106 ? ? 105.20 122.70 -17.50 1.60 Y 
79  1 O  A ALA 109 ? ? C  A ALA 109 ? ? N  A SER 110 ? ? 133.13 122.70 10.43  1.60 Y 
80  1 O  A ASP 111 ? ? C  A ASP 111 ? ? N  A THR 112 ? ? 132.92 122.70 10.22  1.60 Y 
81  1 O  A ALA 113 ? ? C  A ALA 113 ? ? N  A ILE 114 ? ? 133.62 122.70 10.92  1.60 Y 
82  1 O  A ILE 114 ? ? C  A ILE 114 ? ? N  A TYR 115 ? ? 112.22 122.70 -10.48 1.60 Y 
83  1 O  A CYS 117 ? ? C  A CYS 117 ? ? N  A ALA 118 ? ? 133.97 122.70 11.27  1.60 Y 
84  1 CA A GLY 119 ? ? C  A GLY 119 ? ? O  A GLY 119 ? ? 104.15 120.60 -16.45 1.80 N 
85  1 O  A GLY 119 ? ? C  A GLY 119 ? ? N  A GLY 120 ? ? 138.31 123.20 15.11  1.70 Y 
86  1 O  A GLY 120 ? ? C  A GLY 120 ? ? N  A SER 121 ? ? 110.72 122.70 -11.98 1.60 Y 
87  1 N  A SER 121 ? ? CA A SER 121 ? ? C  A SER 121 ? ? 132.25 111.00 21.25  2.70 N 
88  1 CA A SER 121 ? ? C  A SER 121 ? ? O  A SER 121 ? ? 86.69  120.10 -33.41 2.10 N 
89  1 CA A SER 121 ? ? C  A SER 121 ? ? N  A GLY 122 ? ? 130.27 116.20 14.07  2.00 Y 
90  1 C  A SER 121 ? ? N  A GLY 122 ? ? CA A GLY 122 ? ? 160.76 122.30 38.46  2.10 Y 
91  1 N  A GLY 122 ? ? CA A GLY 122 ? ? C  A GLY 122 ? ? 94.78  113.10 -18.32 2.50 N 
92  1 CA A GLY 122 ? ? C  A GLY 122 ? ? O  A GLY 122 ? ? 99.16  120.60 -21.44 1.80 N 
93  1 O  A ILE 123 ? ? C  A ILE 123 ? ? N  A SER 124 ? ? 132.49 122.70 9.79   1.60 Y 
94  1 C  A ILE 123 ? ? N  A SER 124 ? ? CA A SER 124 ? ? 138.88 121.70 17.18  2.50 Y 
95  1 CA A ASP 128 ? ? C  A ASP 128 ? ? N  A VAL 129 ? ? 103.38 117.20 -13.82 2.20 Y 
96  1 O  A VAL 129 ? ? C  A VAL 129 ? ? N  A TRP 130 ? ? 135.25 122.70 12.55  1.60 Y 
97  1 N  A TRP 130 ? ? CA A TRP 130 ? ? C  A TRP 130 ? ? 93.64  111.00 -17.36 2.70 N 
98  1 O  A GLN 132 ? ? C  A GLN 132 ? ? N  A GLY 133 ? ? 107.55 123.20 -15.65 1.70 Y 
99  1 O  A THR 135 ? ? C  A THR 135 ? ? N  A VAL 136 ? ? 135.07 122.70 12.37  1.60 Y 
100 1 O  A THR 137 ? ? C  A THR 137 ? ? N  A VAL 138 ? ? 134.00 122.70 11.30  1.60 Y 
101 1 O  A VAL 138 ? ? C  A VAL 138 ? ? N  A SER 139 ? ? 132.82 122.70 10.12  1.60 Y 
102 1 O  A SER 139 ? ? C  A SER 139 ? ? N  A SER 140 ? ? 132.63 122.70 9.93   1.60 Y 
103 1 CB A SER 140 ? ? CA A SER 140 ? ? C  A SER 140 ? ? 97.72  110.10 -12.38 1.90 N 
104 1 N  A SER 140 ? ? CA A SER 140 ? ? C  A SER 140 ? ? 142.24 111.00 31.24  2.70 N 
105 1 O  A SER 140 ? ? C  A SER 140 ? ? N  A GLY 141 ? ? 134.23 123.20 11.03  1.70 Y 
106 1 N  A GLY 141 ? ? CA A GLY 141 ? ? C  A GLY 141 ? ? 77.99  113.10 -35.11 2.50 N 
107 1 C  A SER 142 ? ? N  A GLY 143 ? ? CA A GLY 143 ? ? 105.04 122.30 -17.26 2.10 Y 
108 1 N  A GLY 144 ? ? CA A GLY 144 ? ? C  A GLY 144 ? ? 89.54  113.10 -23.56 2.50 N 
109 1 N  A GLY 146 ? ? CA A GLY 146 ? ? C  A GLY 146 ? ? 94.06  113.10 -19.04 2.50 N 
110 1 N  A ILE 149 ? ? CA A ILE 149 ? ? C  A ILE 149 ? ? 138.75 111.00 27.75  2.70 N 
111 1 CA A ILE 149 ? ? C  A ILE 149 ? ? N  A GLN 150 ? ? 98.51  117.20 -18.69 2.20 Y 
112 1 O  A ILE 149 ? ? C  A ILE 149 ? ? N  A GLN 150 ? ? 134.15 122.70 11.45  1.60 Y 
113 1 O  A LEU 151 ? ? C  A LEU 151 ? ? N  A THR 152 ? ? 106.35 122.70 -16.35 1.60 Y 
114 1 O  A THR 152 ? ? C  A THR 152 ? ? N  A GLN 153 ? ? 83.69  122.70 -39.01 1.60 Y 
115 1 C  A THR 152 ? ? N  A GLN 153 ? ? CA A GLN 153 ? ? 103.50 121.70 -18.20 2.50 Y 
116 1 N  A SER 154 ? ? CA A SER 154 ? ? C  A SER 154 ? ? 90.04  111.00 -20.96 2.70 N 
117 1 CA A PRO 155 ? ? C  A PRO 155 ? ? O  A PRO 155 ? ? 100.58 120.20 -19.62 2.40 N 
118 1 O  A PRO 155 ? ? C  A PRO 155 ? ? N  A ASP 156 ? ? 134.16 122.70 11.46  1.60 Y 
119 1 C  A VAL 160 ? ? N  A SER 161 ? ? CA A SER 161 ? ? 106.06 121.70 -15.64 2.50 Y 
120 1 O  A SER 161 ? ? C  A SER 161 ? ? N  A LEU 162 ? ? 134.25 122.70 11.55  1.60 Y 
121 1 C  A LEU 162 ? ? N  A GLY 163 ? ? CA A GLY 163 ? ? 140.05 122.30 17.75  2.10 Y 
122 1 O  A ALA 166 ? ? C  A ALA 166 ? ? N  A THR 167 ? ? 133.19 122.70 10.49  1.60 Y 
123 1 CA A LYS 171 ? ? C  A LYS 171 ? ? O  A LYS 171 ? ? 104.99 120.10 -15.11 2.10 N 
124 1 O  A LYS 171 ? ? C  A LYS 171 ? ? N  A SER 172 ? ? 134.65 122.70 11.95  1.60 Y 
125 1 O  A SER 172 ? ? C  A SER 172 ? ? N  A SER 173 ? ? 132.69 122.70 9.99   1.60 Y 
126 1 N  A SER 173 ? ? CA A SER 173 ? ? C  A SER 173 ? ? 89.61  111.00 -21.39 2.70 N 
127 1 CA A SER 173 ? ? C  A SER 173 ? ? N  A GLN 174 ? ? 103.54 117.20 -13.66 2.20 Y 
128 1 CA A GLN 174 ? ? C  A GLN 174 ? ? N  A SER 175 ? ? 103.54 117.20 -13.66 2.20 Y 
129 1 O  A GLN 174 ? ? C  A GLN 174 ? ? N  A SER 175 ? ? 135.72 122.70 13.02  1.60 Y 
130 1 C  A GLN 174 ? ? N  A SER 175 ? ? CA A SER 175 ? ? 145.06 121.70 23.36  2.50 Y 
131 1 N  A SER 175 ? ? CA A SER 175 ? ? CB A SER 175 ? ? 120.59 110.50 10.09  1.50 N 
132 1 N  A SER 175 ? ? CA A SER 175 ? ? C  A SER 175 ? ? 72.99  111.00 -38.01 2.70 N 
133 1 CA A SER 175 ? ? C  A SER 175 ? ? O  A SER 175 ? ? 104.82 120.10 -15.28 2.10 N 
134 1 O  A SER 175 ? ? C  A SER 175 ? ? N  A VAL 176 ? ? 136.21 122.70 13.51  1.60 Y 
135 1 CA A VAL 176 ? ? C  A VAL 176 ? ? N  A LEU 177 ? ? 100.46 117.20 -16.74 2.20 Y 
136 1 O  A VAL 176 ? ? C  A VAL 176 ? ? N  A LEU 177 ? ? 135.77 122.70 13.07  1.60 Y 
137 1 CA A LEU 177 ? ? C  A LEU 177 ? ? N  A TYR 178 ? ? 103.85 117.20 -13.35 2.20 Y 
138 1 O  A LEU 177 ? ? C  A LEU 177 ? ? N  A TYR 178 ? ? 135.74 122.70 13.04  1.60 Y 
139 1 CA A TYR 178 ? ? C  A TYR 178 ? ? O  A TYR 178 ? ? 104.17 120.10 -15.93 2.10 N 
140 1 O  A TYR 178 ? ? C  A TYR 178 ? ? N  A SER 179 ? ? 139.20 122.70 16.50  1.60 Y 
141 1 C  A TYR 178 ? ? N  A SER 179 ? ? CA A SER 179 ? ? 142.57 121.70 20.87  2.50 Y 
142 1 CA A SER 179 ? ? C  A SER 179 ? ? N  A SER 180 ? ? 103.69 117.20 -13.51 2.20 Y 
143 1 N  A ILE 181 ? ? CA A ILE 181 ? ? C  A ILE 181 ? ? 94.73  111.00 -16.27 2.70 N 
144 1 O  A TYR 185 ? ? C  A TYR 185 ? ? N  A LEU 186 ? ? 132.56 122.70 9.86   1.60 Y 
145 1 O  A ALA 187 ? ? C  A ALA 187 ? ? N  A TRP 188 ? ? 112.66 122.70 -10.04 1.60 Y 
146 1 CA A LYS 192 ? ? C  A LYS 192 ? ? O  A LYS 192 ? ? 102.08 120.10 -18.02 2.10 N 
147 1 O  A PRO 193 ? ? C  A PRO 193 ? ? N  A GLY 194 ? ? 135.45 123.20 12.25  1.70 Y 
148 1 C  A PRO 196 ? ? N  A PRO 197 ? ? CA A PRO 197 ? ? 109.69 119.30 -9.61  1.50 Y 
149 1 O  A PRO 197 ? ? C  A PRO 197 ? ? N  A LYS 198 ? ? 134.80 122.70 12.10  1.60 Y 
150 1 O  A LEU 199 ? ? C  A LEU 199 ? ? N  A LEU 200 ? ? 135.90 122.70 13.20  1.60 Y 
151 1 CA A ILE 201 ? ? C  A ILE 201 ? ? O  A ILE 201 ? ? 102.24 120.10 -17.86 2.10 N 
152 1 O  A ILE 201 ? ? C  A ILE 201 ? ? N  A TYR 202 ? ? 135.15 122.70 12.45  1.60 Y 
153 1 CA A TYR 202 ? ? C  A TYR 202 ? ? O  A TYR 202 ? ? 106.06 120.10 -14.04 2.10 N 
154 1 O  A TYR 202 ? ? C  A TYR 202 ? ? N  A TRP 203 ? ? 133.88 122.70 11.18  1.60 Y 
155 1 O  A TRP 203 ? ? C  A TRP 203 ? ? N  A ALA 204 ? ? 132.56 122.70 9.86   1.60 Y 
156 1 CB A ALA 204 ? ? CA A ALA 204 ? ? C  A ALA 204 ? ? 122.49 110.10 12.39  1.50 N 
157 1 N  A ALA 204 ? ? CA A ALA 204 ? ? CB A ALA 204 ? ? 122.38 110.10 12.28  1.40 N 
158 1 N  A ALA 204 ? ? CA A ALA 204 ? ? C  A ALA 204 ? ? 58.76  111.00 -52.24 2.70 N 
159 1 C  A SER 205 ? ? N  A THR 206 ? ? CA A THR 206 ? ? 106.69 121.70 -15.01 2.50 Y 
160 1 N  A THR 206 ? ? CA A THR 206 ? ? C  A THR 206 ? ? 93.42  111.00 -17.58 2.70 N 
161 1 O  A GLU 208 ? ? C  A GLU 208 ? ? N  A SER 209 ? ? 132.86 122.70 10.16  1.60 Y 
162 1 N  A SER 209 ? ? CA A SER 209 ? ? C  A SER 209 ? ? 80.28  111.00 -30.72 2.70 N 
163 1 O  A VAL 211 ? ? C  A VAL 211 ? ? N  A PRO 212 ? ? 132.62 121.10 11.52  1.90 Y 
164 1 O  A PRO 212 ? ? C  A PRO 212 ? ? N  A ASP 213 ? ? 138.16 122.70 15.46  1.60 Y 
165 1 CA A ASP 213 ? ? C  A ASP 213 ? ? O  A ASP 213 ? ? 106.94 120.10 -13.16 2.10 N 
166 1 O  A PHE 215 ? ? C  A PHE 215 ? ? N  A SER 216 ? ? 132.32 122.70 9.62   1.60 Y 
167 1 CA A ASP 223 ? ? C  A ASP 223 ? ? O  A ASP 223 ? ? 106.64 120.10 -13.46 2.10 N 
168 1 O  A ASP 223 ? ? C  A ASP 223 ? ? N  A PHE 224 ? ? 135.77 122.70 13.07  1.60 Y 
169 1 O  A SER 229 ? ? C  A SER 229 ? ? N  A SER 230 ? ? 108.17 122.70 -14.53 1.60 Y 
170 1 O  A LEU 231 ? ? C  A LEU 231 ? ? N  A GLN 232 ? ? 133.09 122.70 10.39  1.60 Y 
171 1 O  A ALA 233 ? ? C  A ALA 233 ? ? N  A GLU 234 ? ? 135.01 122.70 12.31  1.60 Y 
172 1 O  A ASP 235 ? ? C  A ASP 235 ? ? N  A VAL 236 ? ? 132.48 122.70 9.78   1.60 Y 
173 1 O  A VAL 236 ? ? C  A VAL 236 ? ? N  A ALA 237 ? ? 107.89 122.70 -14.81 1.60 Y 
174 1 O  A ALA 237 ? ? C  A ALA 237 ? ? N  A VAL 238 ? ? 135.08 122.70 12.38  1.60 Y 
175 1 O  A VAL 238 ? ? C  A VAL 238 ? ? N  A TYR 239 ? ? 113.10 122.70 -9.60  1.60 Y 
176 1 O  A CYS 241 ? ? C  A CYS 241 ? ? N  A GLN 242 ? ? 136.31 122.70 13.61  1.60 Y 
177 1 O  A GLN 243 ? ? C  A GLN 243 ? ? N  A TYR 244 ? ? 133.67 122.70 10.97  1.60 Y 
178 1 CA A TYR 245 ? ? C  A TYR 245 ? ? O  A TYR 245 ? ? 107.33 120.10 -12.77 2.10 N 
179 1 O  A TYR 245 ? ? C  A TYR 245 ? ? N  A SER 246 ? ? 136.19 122.70 13.49  1.60 Y 
180 1 N  A THR 247 ? ? CA A THR 247 ? ? C  A THR 247 ? ? 84.28  111.00 -26.72 2.70 N 
181 1 O  A TYR 249 ? ? C  A TYR 249 ? ? N  A THR 250 ? ? 133.19 122.70 10.49  1.60 Y 
182 1 N  A GLY 252 ? ? CA A GLY 252 ? ? C  A GLY 252 ? ? 92.30  113.10 -20.80 2.50 N 
183 1 CA A GLY 252 ? ? C  A GLY 252 ? ? O  A GLY 252 ? ? 131.85 120.60 11.25  1.80 N 
184 1 N  A GLN 253 ? ? CA A GLN 253 ? ? C  A GLN 253 ? ? 89.51  111.00 -21.49 2.70 N 
185 1 C  A GLY 254 ? ? N  A THR 255 ? ? CA A THR 255 ? ? 177.59 121.70 55.89  2.50 Y 
186 1 O  A THR 255 ? ? C  A THR 255 ? ? N  A LYS 256 ? ? 134.45 122.70 11.75  1.60 Y 
187 1 C  A THR 255 ? ? N  A LYS 256 ? ? CA A LYS 256 ? ? 104.17 121.70 -17.53 2.50 Y 
188 1 CA A VAL 257 ? ? C  A VAL 257 ? ? O  A VAL 257 ? ? 105.38 120.10 -14.72 2.10 N 
189 1 O  A VAL 257 ? ? C  A VAL 257 ? ? N  A GLU 258 ? ? 136.80 122.70 14.10  1.60 Y 
190 1 N  A ILE 259 ? ? CA A ILE 259 ? ? C  A ILE 259 ? ? 92.34  111.00 -18.66 2.70 N 
191 1 O  A LYS 261 ? ? C  A LYS 261 ? ? N  A HIS 262 ? ? 137.27 122.70 14.57  1.60 Y 
192 1 C  A LYS 261 ? ? N  A HIS 262 ? ? CA A HIS 262 ? ? 146.20 121.70 24.50  2.50 Y 
193 1 O  A HIS 262 ? ? C  A HIS 262 ? ? N  A HIS 263 ? ? 138.67 122.70 15.97  1.60 Y 
194 1 C  A HIS 262 ? ? N  A HIS 263 ? ? CA A HIS 263 ? ? 162.89 121.70 41.19  2.50 Y 
195 1 N  A HIS 263 ? ? CA A HIS 263 ? ? CB A HIS 263 ? ? 96.45  110.60 -14.15 1.80 N 
196 1 N  A HIS 263 ? ? CA A HIS 263 ? ? C  A HIS 263 ? ? 141.92 111.00 30.92  2.70 N 
197 1 CA A HIS 263 ? ? C  A HIS 263 ? ? O  A HIS 263 ? ? 137.62 120.10 17.52  2.10 N 
198 1 N  A HIS 264 ? ? CA A HIS 264 ? ? CB A HIS 264 ? ? 99.75  110.60 -10.85 1.80 N 
199 1 N  A HIS 264 ? ? CA A HIS 264 ? ? C  A HIS 264 ? ? 145.42 111.00 34.42  2.70 N 
200 1 N  A HIS 265 ? ? CA A HIS 265 ? ? C  A HIS 265 ? ? 138.61 111.00 27.61  2.70 N 
201 1 O  A HIS 265 ? ? C  A HIS 265 ? ? N  A HIS 266 ? ? 111.98 122.70 -10.72 1.60 Y 
202 1 C  A HIS 265 ? ? N  A HIS 266 ? ? CA A HIS 266 ? ? 94.64  121.70 -27.06 2.50 Y 
203 1 O  A HIS 266 ? ? C  A HIS 266 ? ? N  A HIS 267 ? ? 112.71 122.70 -9.99  1.60 Y 
204 1 C  A HIS 266 ? ? N  A HIS 267 ? ? CA A HIS 267 ? ? 99.21  121.70 -22.49 2.50 Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 3   ? ? -117.65 -85.46  
2  1 MET A 20  ? ? 63.62   68.30   
3  1 SER A 77  ? ? -55.37  -9.97   
4  1 SER A 124 ? ? 59.94   -48.51  
5  1 THR A 125 ? ? -144.14 54.15   
6  1 MET A 127 ? ? 52.50   75.13   
7  1 THR A 152 ? ? -126.79 -128.48 
8  1 PRO A 155 ? ? -66.44  31.34   
9  1 ASP A 156 ? ? 55.07   -153.94 
10 1 VAL A 176 ? ? -59.83  77.25   
11 1 TYR A 178 ? ? -63.61  77.16   
12 1 LEU A 200 ? ? -98.84  -63.22  
13 1 THR A 255 ? ? -124.44 -123.47 
14 1 HIS A 263 ? ? 34.20   -175.69 
15 1 HIS A 265 ? ? 179.58  56.15   
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 GLN A 17  ? ? PRO A 18  ? ? -46.56  
2 1 THR A 152 ? ? GLN A 153 ? ? -139.78 
# 
loop_
_pdbx_validate_main_chain_plane.id 
_pdbx_validate_main_chain_plane.PDB_model_num 
_pdbx_validate_main_chain_plane.auth_comp_id 
_pdbx_validate_main_chain_plane.auth_asym_id 
_pdbx_validate_main_chain_plane.auth_seq_id 
_pdbx_validate_main_chain_plane.PDB_ins_code 
_pdbx_validate_main_chain_plane.label_alt_id 
_pdbx_validate_main_chain_plane.improper_torsion_angle 
1  1 GLN A 17  ? ? 23.64   
2  1 GLN A 22  ? ? 10.79   
3  1 VAL A 26  ? ? -10.42  
4  1 GLY A 49  ? ? -13.19  
5  1 ILE A 51  ? ? 15.76   
6  1 PRO A 62  ? ? -149.38 
7  1 GLY A 65  ? ? 10.67   
8  1 MET A 69  ? ? -13.01  
9  1 ASP A 76  ? ? -15.47  
10 1 GLY A 120 ? ? -10.98  
11 1 SER A 121 ? ? 33.02   
12 1 THR A 125 ? ? -19.29  
13 1 GLY A 131 ? ? 13.06   
14 1 GLN A 132 ? ? 10.28   
15 1 LEU A 151 ? ? -17.27  
16 1 THR A 152 ? ? -36.93  
17 1 SER A 154 ? ? -11.27  
18 1 SER A 173 ? ? -10.02  
19 1 GLN A 174 ? ? -13.45  
20 1 SER A 175 ? ? -10.82  
21 1 ILE A 181 ? ? -22.10  
22 1 ARG A 207 ? ? -10.46  
23 1 TYR A 244 ? ? 11.10   
24 1 GLY A 254 ? ? -18.17  
25 1 HIS A 265 ? ? -12.62  
26 1 HIS A 266 ? ? -13.89  
# 
loop_
_pdbx_validate_polymer_linkage.id 
_pdbx_validate_polymer_linkage.PDB_model_num 
_pdbx_validate_polymer_linkage.auth_atom_id_1 
_pdbx_validate_polymer_linkage.auth_asym_id_1 
_pdbx_validate_polymer_linkage.auth_comp_id_1 
_pdbx_validate_polymer_linkage.auth_seq_id_1 
_pdbx_validate_polymer_linkage.PDB_ins_code_1 
_pdbx_validate_polymer_linkage.label_alt_id_1 
_pdbx_validate_polymer_linkage.auth_atom_id_2 
_pdbx_validate_polymer_linkage.auth_asym_id_2 
_pdbx_validate_polymer_linkage.auth_comp_id_2 
_pdbx_validate_polymer_linkage.auth_seq_id_2 
_pdbx_validate_polymer_linkage.PDB_ins_code_2 
_pdbx_validate_polymer_linkage.label_alt_id_2 
_pdbx_validate_polymer_linkage.dist 
1  1 C A PHE 50  ? ? N A ILE 51  ? ? 1.63 
2  1 C A THR 52  ? ? N A TYR 53  ? ? 1.64 
3  1 C A TRP 104 ? ? N A SER 105 ? ? 1.61 
4  1 C A SER 105 ? ? N A SER 106 ? ? 1.04 
5  1 C A GLY 122 ? ? N A ILE 123 ? ? 1.75 
6  1 C A GLN 132 ? ? N A GLY 133 ? ? 1.19 
7  1 C A ASP 148 ? ? N A ILE 149 ? ? 1.71 
8  1 C A LEU 151 ? ? N A THR 152 ? ? 1.19 
9  1 C A SER 179 ? ? N A SER 180 ? ? 1.64 
10 1 C A SER 180 ? ? N A ILE 181 ? ? 1.75 
11 1 C A ILE 181 ? ? N A ASN 182 ? ? 1.64 
12 1 C A ARG 207 ? ? N A GLU 208 ? ? 1.60 
13 1 C A ILE 228 ? ? N A SER 229 ? ? 1.60 
14 1 C A SER 229 ? ? N A SER 230 ? ? 1.11 
15 1 C A VAL 236 ? ? N A ALA 237 ? ? 1.15 
16 1 C A SER 246 ? ? N A THR 247 ? ? 1.67 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
_entry.id   XXXX 
# 
_pdbx_seq_map_depositor_info.entity_id             1 
_pdbx_seq_map_depositor_info.auth_asym_id          A 
_pdbx_seq_map_depositor_info.one_letter_code       
;KYLLPTAAAGLLLLAAQPAMAQMQLVQSGTEVKKPGESLKISCKGSGYGFITYWIGWVRQMPGKGLEWMGIIYPGDSETR
YSPSFQGQVTISADKSINTAYLQWSSLKASDTAIYYCAGGSGISTPMDVWGQGTTVTVSSGSGGGGSDIQLTQSPDSLAV
SLGERATINCKSSQSVLYSSINKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYY
CQQYYSTPYTFGQGTKVEIKKHHHHHHC
;
_pdbx_seq_map_depositor_info.one_letter_code_mod   
;KYLLPTAAAGLLLLAAQPAMAQMQLVQSGTEVKKPGESLKISCKGSGYGFITYWIGWVRQMPGKGLEWMGIIYPGDSETR
YSPSFQGQVTISADKSINTAYLQWSSLKASDTAIYYCAGGSGISTPMDVWGQGTTVTVSSGSGGGGSDIQLTQSPDSLAV
SLGERATINCKSSQSVLYSSINKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYY
CQQYYSTPYTFGQGTKVEIKKHHHHHHC
;
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_auth_seq_id 
_atom_site.pdbx_auth_comp_id 
_atom_site.pdbx_auth_asym_id 
_atom_site.pdbx_auth_atom_name 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N    . LYS A 1 1   ? -0.595 -0.110  0.807  1.00 16.56 ? 1   LYS A N    1   LYS A N    1 
ATOM 2    C CA   . LYS A 1 1   ? 0.656  0.583   0.385  1.00 16.56 ? 1   LYS A CA   1   LYS A CA   1 
ATOM 3    C C    . LYS A 1 1   ? 0.654  1.845   -0.575 1.00 16.56 ? 1   LYS A C    1   LYS A C    1 
ATOM 4    O O    . LYS A 1 1   ? -0.233 2.043   -1.490 1.00 16.56 ? 1   LYS A O    1   LYS A O    1 
ATOM 5    C CB   . LYS A 1 1   ? 1.551  -0.483  -0.249 1.00 16.56 ? 1   LYS A CB   1   LYS A CB   1 
ATOM 6    C CG   . LYS A 1 1   ? 2.020  -1.565  0.715  1.00 16.56 ? 1   LYS A CG   1   LYS A CG   1 
ATOM 7    C CD   . LYS A 1 1   ? 2.932  -2.566  0.021  1.00 16.56 ? 1   LYS A CD   1   LYS A CD   1 
ATOM 8    C CE   . LYS A 1 1   ? 3.413  -3.640  0.986  1.00 16.56 ? 1   LYS A CE   1   LYS A CE   1 
ATOM 9    N NZ   . LYS A 1 1   ? 4.295  -4.634  0.318  1.00 16.56 ? 1   LYS A NZ   1   LYS A NZ   1 
ATOM 10   H H1   . LYS A 1 1   ? -0.367 -0.875  1.408  1.00 16.56 ? 1   LYS A H1   1   LYS A 1H   1 
ATOM 11   H H2   . LYS A 1 1   ? -1.184 0.534   1.296  1.00 16.56 ? 1   LYS A H2   1   LYS A 2H   1 
ATOM 12   H H3   . LYS A 1 1   ? -1.075 -0.453  -0.001 1.00 16.56 ? 1   LYS A H3   1   LYS A 3H   1 
ATOM 13   H HA   . LYS A 1 1   ? 1.133  1.005   1.270  1.00 16.56 ? 1   LYS A HA   1   LYS A HA   1 
ATOM 14   H HB2  . LYS A 1 1   ? 1.016  -0.970  -1.064 1.00 16.56 ? 1   LYS A HB2  1   LYS A 1HB  1 
ATOM 15   H HB3  . LYS A 1 1   ? 2.436  -0.009  -0.675 1.00 16.56 ? 1   LYS A HB3  1   LYS A 2HB  1 
ATOM 16   H HG2  . LYS A 1 1   ? 2.563  -1.105  1.542  1.00 16.56 ? 1   LYS A HG2  1   LYS A 1HG  1 
ATOM 17   H HG3  . LYS A 1 1   ? 1.156  -2.092  1.119  1.00 16.56 ? 1   LYS A HG3  1   LYS A 2HG  1 
ATOM 18   H HD2  . LYS A 1 1   ? 2.392  -3.042  -0.799 1.00 16.56 ? 1   LYS A HD2  1   LYS A 1HD  1 
ATOM 19   H HD3  . LYS A 1 1   ? 3.797  -2.046  -0.390 1.00 16.56 ? 1   LYS A HD3  1   LYS A 2HD  1 
ATOM 20   H HE2  . LYS A 1 1   ? 3.963  -3.174  1.802  1.00 16.56 ? 1   LYS A HE2  1   LYS A 1HE  1 
ATOM 21   H HE3  . LYS A 1 1   ? 2.553  -4.161  1.408  1.00 16.56 ? 1   LYS A HE3  1   LYS A 2HE  1 
ATOM 22   H HZ1  . LYS A 1 1   ? 4.591  -5.327  0.990  1.00 16.56 ? 1   LYS A HZ1  1   LYS A 1HZ  1 
ATOM 23   H HZ2  . LYS A 1 1   ? 3.788  -5.086  -0.431 1.00 16.56 ? 1   LYS A HZ2  1   LYS A 2HZ  1 
ATOM 24   H HZ3  . LYS A 1 1   ? 5.105  -4.165  -0.061 1.00 16.56 ? 1   LYS A HZ3  1   LYS A 3HZ  1 
ATOM 25   N N    . TYR A 1 2   ? 1.805  2.646   -0.335 1.00 14.83 ? 2   TYR A N    2   TYR A N    1 
ATOM 26   C CA   . TYR A 1 2   ? 2.022  3.978   -0.813 1.00 14.83 ? 2   TYR A CA   2   TYR A CA   1 
ATOM 27   C C    . TYR A 1 2   ? 3.499  4.041   -1.363 1.00 14.83 ? 2   TYR A C    2   TYR A C    1 
ATOM 28   O O    . TYR A 1 2   ? 4.459  3.393   -0.781 1.00 14.83 ? 2   TYR A O    2   TYR A O    1 
ATOM 29   C CB   . TYR A 1 2   ? 1.772  4.996   0.303  1.00 14.83 ? 2   TYR A CB   2   TYR A CB   1 
ATOM 30   C CG   . TYR A 1 2   ? 0.431  4.838   0.984  1.00 14.83 ? 2   TYR A CG   2   TYR A CG   1 
ATOM 31   C CD1  . TYR A 1 2   ? 0.333  4.116   2.165  1.00 14.83 ? 2   TYR A CD1  2   TYR A CD1  1 
ATOM 32   C CD2  . TYR A 1 2   ? -0.702 5.414   0.428  1.00 14.83 ? 2   TYR A CD2  2   TYR A CD2  1 
ATOM 33   C CE1  . TYR A 1 2   ? -0.892 3.972   2.787  1.00 14.83 ? 2   TYR A CE1  2   TYR A CE1  1 
ATOM 34   C CE2  . TYR A 1 2   ? -1.927 5.270   1.050  1.00 14.83 ? 2   TYR A CE2  2   TYR A CE2  1 
ATOM 35   C CZ   . TYR A 1 2   ? -2.023 4.552   2.225  1.00 14.83 ? 2   TYR A CZ   2   TYR A CZ   1 
ATOM 36   O OH   . TYR A 1 2   ? -3.243 4.408   2.845  1.00 14.83 ? 2   TYR A OH   2   TYR A OH   1 
ATOM 37   H H    . TYR A 1 2   ? 2.566  2.315   0.234  1.00 14.83 ? 2   TYR A H    2   TYR A H    1 
ATOM 38   H HA   . TYR A 1 2   ? 1.321  4.173   -1.625 1.00 14.83 ? 2   TYR A HA   2   TYR A HA   1 
ATOM 39   H HB2  . TYR A 1 2   ? 2.551  4.904   1.060  1.00 14.83 ? 2   TYR A HB2  2   TYR A 1HB  1 
ATOM 40   H HB3  . TYR A 1 2   ? 1.829  6.004   -0.106 1.00 14.83 ? 2   TYR A HB3  2   TYR A 2HB  1 
ATOM 41   H HD1  . TYR A 1 2   ? 1.223  3.663   2.602  1.00 14.83 ? 2   TYR A HD1  2   TYR A HD1  1 
ATOM 42   H HD2  . TYR A 1 2   ? -0.625 5.981   -0.500 1.00 14.83 ? 2   TYR A HD2  2   TYR A HD2  1 
ATOM 43   H HE1  . TYR A 1 2   ? -0.968 3.405   3.714  1.00 14.83 ? 2   TYR A HE1  2   TYR A HE1  1 
ATOM 44   H HE2  . TYR A 1 2   ? -2.817 5.723   0.613  1.00 14.83 ? 2   TYR A HE2  2   TYR A HE2  1 
ATOM 45   H HH   . TYR A 1 2   ? -3.139 3.873   3.635  1.00 14.83 ? 2   TYR A HH   2   TYR A HH   1 
ATOM 46   N N    . LEU A 1 3   ? 3.571  4.694   -2.575 1.00 15.04 ? 3   LEU A N    3   LEU A N    1 
ATOM 47   C CA   . LEU A 1 3   ? 4.716  5.023   -3.370 1.00 15.04 ? 3   LEU A CA   3   LEU A CA   1 
ATOM 48   C C    . LEU A 1 3   ? 4.653  6.483   -3.380 1.00 15.04 ? 3   LEU A C    3   LEU A C    1 
ATOM 49   O O    . LEU A 1 3   ? 5.475  7.064   -2.613 1.00 15.04 ? 3   LEU A O    3   LEU A O    1 
ATOM 50   C CB   . LEU A 1 3   ? 4.657  4.444   -4.789 1.00 15.04 ? 3   LEU A CB   3   LEU A CB   1 
ATOM 51   C CG   . LEU A 1 3   ? 4.786  2.919   -4.891 1.00 15.04 ? 3   LEU A CG   3   LEU A CG   1 
ATOM 52   C CD1  . LEU A 1 3   ? 4.576  2.487   -6.336 1.00 15.04 ? 3   LEU A CD1  3   LEU A CD1  1 
ATOM 53   C CD2  . LEU A 1 3   ? 6.155  2.490   -4.385 1.00 15.04 ? 3   LEU A CD2  3   LEU A CD2  1 
ATOM 54   H H    . LEU A 1 3   ? 2.743  5.116   -2.897 1.00 15.04 ? 3   LEU A H    3   LEU A H    1 
ATOM 55   H HA   . LEU A 1 3   ? 5.602  4.610   -2.889 1.00 15.04 ? 3   LEU A HA   3   LEU A HA   1 
ATOM 56   H HB2  . LEU A 1 3   ? 3.707  4.727   -5.240 1.00 15.04 ? 3   LEU A HB2  3   LEU A 1HB  1 
ATOM 57   H HB3  . LEU A 1 3   ? 5.460  4.885   -5.379 1.00 15.04 ? 3   LEU A HB3  3   LEU A 2HB  1 
ATOM 58   H HG   . LEU A 1 3   ? 4.011  2.447   -4.286 1.00 15.04 ? 3   LEU A HG   3   LEU A HG   1 
ATOM 59   H HD11 . LEU A 1 3   ? 4.668  1.403   -6.408 1.00 15.04 ? 3   LEU A HD11 3   LEU A 1HD1 1 
ATOM 60   H HD12 . LEU A 1 3   ? 3.582  2.789   -6.666 1.00 15.04 ? 3   LEU A HD12 3   LEU A 2HD1 1 
ATOM 61   H HD13 . LEU A 1 3   ? 5.328  2.957   -6.969 1.00 15.04 ? 3   LEU A HD13 3   LEU A 3HD1 1 
ATOM 62   H HD21 . LEU A 1 3   ? 6.246  1.406   -4.457 1.00 15.04 ? 3   LEU A HD21 3   LEU A 1HD2 1 
ATOM 63   H HD22 . LEU A 1 3   ? 6.930  2.961   -4.990 1.00 15.04 ? 3   LEU A HD22 3   LEU A 2HD2 1 
ATOM 64   H HD23 . LEU A 1 3   ? 6.271  2.796   -3.345 1.00 15.04 ? 3   LEU A HD23 3   LEU A 3HD2 1 
ATOM 65   N N    . LEU A 1 4   ? 3.768  6.940   -4.453 1.00 13.60 ? 4   LEU A N    4   LEU A N    1 
ATOM 66   C CA   . LEU A 1 4   ? 3.586  8.403   -4.884 1.00 13.60 ? 4   LEU A CA   4   LEU A CA   1 
ATOM 67   C C    . LEU A 1 4   ? 3.210  9.358   -3.785 1.00 13.60 ? 4   LEU A C    4   LEU A C    1 
ATOM 68   O O    . LEU A 1 4   ? 4.123  10.301  -3.859 1.00 13.60 ? 4   LEU A O    4   LEU A O    1 
ATOM 69   C CB   . LEU A 1 4   ? 2.505  8.515   -5.967 1.00 13.60 ? 4   LEU A CB   4   LEU A CB   1 
ATOM 70   C CG   . LEU A 1 4   ? 2.153  9.941   -6.410 1.00 13.60 ? 4   LEU A CG   4   LEU A CG   1 
ATOM 71   C CD1  . LEU A 1 4   ? 3.384  10.605  -7.011 1.00 13.60 ? 4   LEU A CD1  4   LEU A CD1  1 
ATOM 72   C CD2  . LEU A 1 4   ? 1.012  9.893   -7.415 1.00 13.60 ? 4   LEU A CD2  4   LEU A CD2  1 
ATOM 73   H H    . LEU A 1 4   ? 3.170  6.188   -4.904 1.00 13.60 ? 4   LEU A H    4   LEU A H    1 
ATOM 74   H HA   . LEU A 1 4   ? 4.528  8.762   -5.296 1.00 13.60 ? 4   LEU A HA   4   LEU A HA   1 
ATOM 75   H HB2  . LEU A 1 4   ? 2.837  7.967   -6.847 1.00 13.60 ? 4   LEU A HB2  4   LEU A 1HB  1 
ATOM 76   H HB3  . LEU A 1 4   ? 1.593  8.048   -5.596 1.00 13.60 ? 4   LEU A HB3  4   LEU A 2HB  1 
ATOM 77   H HG   . LEU A 1 4   ? 1.848  10.527  -5.542 1.00 13.60 ? 4   LEU A HG   4   LEU A HG   1 
ATOM 78   H HD11 . LEU A 1 4   ? 3.134  11.619  -7.326 1.00 13.60 ? 4   LEU A HD11 4   LEU A 1HD1 1 
ATOM 79   H HD12 . LEU A 1 4   ? 4.178  10.644  -6.265 1.00 13.60 ? 4   LEU A HD12 4   LEU A 2HD1 1 
ATOM 80   H HD13 . LEU A 1 4   ? 3.723  10.031  -7.873 1.00 13.60 ? 4   LEU A HD13 4   LEU A 3HD1 1 
ATOM 81   H HD21 . LEU A 1 4   ? 0.761  10.907  -7.729 1.00 13.60 ? 4   LEU A HD21 4   LEU A 1HD2 1 
ATOM 82   H HD22 . LEU A 1 4   ? 1.316  9.309   -8.283 1.00 13.60 ? 4   LEU A HD22 4   LEU A 2HD2 1 
ATOM 83   H HD23 . LEU A 1 4   ? 0.139  9.430   -6.953 1.00 13.60 ? 4   LEU A HD23 4   LEU A 3HD2 1 
ATOM 84   N N    . PRO A 1 5   ? 2.161  9.007   -2.808 1.00 12.70 ? 5   PRO A N    5   PRO A N    1 
ATOM 85   C CA   . PRO A 1 5   ? 1.813  10.021  -1.849 1.00 12.70 ? 5   PRO A CA   5   PRO A CA   1 
ATOM 86   C C    . PRO A 1 5   ? 2.997  10.245  -1.019 1.00 12.70 ? 5   PRO A C    5   PRO A C    1 
ATOM 87   O O    . PRO A 1 5   ? 3.171  11.546  -0.942 1.00 12.70 ? 5   PRO A O    5   PRO A O    1 
ATOM 88   C CB   . PRO A 1 5   ? 0.656  9.417   -1.048 1.00 12.70 ? 5   PRO A CB   5   PRO A CB   1 
ATOM 89   C CG   . PRO A 1 5   ? -0.035 8.524   -2.021 1.00 12.70 ? 5   PRO A CG   5   PRO A CG   1 
ATOM 90   C CD   . PRO A 1 5   ? 1.081  7.905   -2.819 1.00 12.70 ? 5   PRO A CD   5   PRO A CD   1 
ATOM 91   H HA   . PRO A 1 5   ? 1.477  10.923  -2.382 1.00 12.70 ? 5   PRO A HA   5   PRO A HA   1 
ATOM 92   H HB2  . PRO A 1 5   ? 1.046  8.874   -0.174 1.00 12.70 ? 5   PRO A HB2  5   PRO A 1HB  1 
ATOM 93   H HB3  . PRO A 1 5   ? 0.005  10.217  -0.665 1.00 12.70 ? 5   PRO A HB3  5   PRO A 2HB  1 
ATOM 94   H HG2  . PRO A 1 5   ? -0.640 7.776   -1.487 1.00 12.70 ? 5   PRO A HG2  5   PRO A 1HG  1 
ATOM 95   H HG3  . PRO A 1 5   ? -0.729 9.107   -2.644 1.00 12.70 ? 5   PRO A HG3  5   PRO A 2HG  1 
ATOM 96   H HD2  . PRO A 1 5   ? 1.432  6.993   -2.313 1.00 12.70 ? 5   PRO A HD2  5   PRO A 1HD  1 
ATOM 97   H HD3  . PRO A 1 5   ? 0.722  7.673   -3.833 1.00 12.70 ? 5   PRO A HD3  5   PRO A 2HD  1 
ATOM 98   N N    . THR A 1 6   ? 3.853  9.009   -0.752 1.00 12.70 ? 6   THR A N    6   THR A N    1 
ATOM 99   C CA   . THR A 1 6   ? 4.976  9.113   0.206  1.00 12.70 ? 6   THR A CA   6   THR A CA   1 
ATOM 100  C C    . THR A 1 6   ? 6.028  10.007  -0.368 1.00 12.70 ? 6   THR A C    6   THR A C    1 
ATOM 101  O O    . THR A 1 6   ? 6.584  10.753  0.568  1.00 12.70 ? 6   THR A O    6   THR A O    1 
ATOM 102  C CB   . THR A 1 6   ? 5.595  7.743   0.539  1.00 12.70 ? 6   THR A CB   6   THR A CB   1 
ATOM 103  O OG1  . THR A 1 6   ? 4.597  6.894   1.120  1.00 12.70 ? 6   THR A OG1  6   THR A OG1  1 
ATOM 104  C CG2  . THR A 1 6   ? 6.751  7.902   1.514  1.00 12.70 ? 6   THR A CG2  6   THR A CG2  1 
ATOM 105  H H    . THR A 1 6   ? 3.667  8.087   -1.238 1.00 12.70 ? 6   THR A H    6   THR A H    1 
ATOM 106  H HA   . THR A 1 6   ? 4.599  9.541   1.136  1.00 12.70 ? 6   THR A HA   6   THR A HA   1 
ATOM 107  H HB   . THR A 1 6   ? 5.960  7.277   -0.377 1.00 12.70 ? 6   THR A HB   6   THR A HB   1 
ATOM 108  H HG1  . THR A 1 6   ? 4.864  5.976   1.026  1.00 12.70 ? 6   THR A HG1  6   THR A HG1  1 
ATOM 109  H HG21 . THR A 1 6   ? 7.176  6.923   1.737  1.00 12.70 ? 6   THR A HG21 6   THR A 1HG2 1 
ATOM 110  H HG22 . THR A 1 6   ? 7.517  8.537   1.070  1.00 12.70 ? 6   THR A HG22 6   THR A 2HG2 1 
ATOM 111  H HG23 . THR A 1 6   ? 6.390  8.358   2.435  1.00 12.70 ? 6   THR A HG23 6   THR A 3HG2 1 
ATOM 112  N N    . ALA A 1 7   ? 6.320  9.804   -1.864 1.00 11.91 ? 7   ALA A N    7   ALA A N    1 
ATOM 113  C CA   . ALA A 1 7   ? 7.333  10.626  -2.465 1.00 11.91 ? 7   ALA A CA   7   ALA A CA   1 
ATOM 114  C C    . ALA A 1 7   ? 6.956  12.087  -2.368 1.00 11.91 ? 7   ALA A C    7   ALA A C    1 
ATOM 115  O O    . ALA A 1 7   ? 8.000  12.767  -1.888 1.00 11.91 ? 7   ALA A O    7   ALA A O    1 
ATOM 116  C CB   . ALA A 1 7   ? 7.553  10.223  -3.915 1.00 11.91 ? 7   ALA A CB   7   ALA A CB   1 
ATOM 117  H H    . ALA A 1 7   ? 5.946  9.009   -2.485 1.00 11.91 ? 7   ALA A H    7   ALA A H    1 
ATOM 118  H HA   . ALA A 1 7   ? 8.261  10.478  -1.913 1.00 11.91 ? 7   ALA A HA   7   ALA A HA   1 
ATOM 119  H HB1  . ALA A 1 7   ? 8.323  10.856  -4.356 1.00 11.91 ? 7   ALA A HB1  7   ALA A 1HB  1 
ATOM 120  H HB2  . ALA A 1 7   ? 7.871  9.181   -3.959 1.00 11.91 ? 7   ALA A HB2  7   ALA A 2HB  1 
ATOM 121  H HB3  . ALA A 1 7   ? 6.624  10.342  -4.471 1.00 11.91 ? 7   ALA A HB3  7   ALA A 3HB  1 
ATOM 122  N N    . ALA A 1 8   ? 5.468  12.367  -2.551 1.00 10.57 ? 8   ALA A N    8   ALA A N    1 
ATOM 123  C CA   . ALA A 1 8   ? 5.120  13.786  -2.611 1.00 10.57 ? 8   ALA A CA   8   ALA A CA   1 
ATOM 124  C C    . ALA A 1 8   ? 5.382  14.464  -1.298 1.00 10.57 ? 8   ALA A C    8   ALA A C    1 
ATOM 125  O O    . ALA A 1 8   ? 6.046  15.592  -1.468 1.00 10.57 ? 8   ALA A O    8   ALA A O    1 
ATOM 126  C CB   . ALA A 1 8   ? 3.662  13.968  -3.007 1.00 10.57 ? 8   ALA A CB   8   ALA A CB   1 
ATOM 127  H H    . ALA A 1 8   ? 4.897  11.641  -2.922 1.00 10.57 ? 8   ALA A H    8   ALA A H    1 
ATOM 128  H HA   . ALA A 1 8   ? 5.749  14.258  -3.366 1.00 10.57 ? 8   ALA A HA   8   ALA A HA   1 
ATOM 129  H HB1  . ALA A 1 8   ? 3.422  15.031  -3.034 1.00 10.57 ? 8   ALA A HB1  8   ALA A 1HB  1 
ATOM 130  H HB2  . ALA A 1 8   ? 3.497  13.535  -3.994 1.00 10.57 ? 8   ALA A HB2  8   ALA A 2HB  1 
ATOM 131  H HB3  . ALA A 1 8   ? 3.023  13.470  -2.280 1.00 10.57 ? 8   ALA A HB3  8   ALA A 3HB  1 
ATOM 132  N N    . ALA A 1 9   ? 5.049  13.546  -0.164 1.00 10.00 ? 9   ALA A N    9   ALA A N    1 
ATOM 133  C CA   . ALA A 1 9   ? 5.169  14.022  1.261  1.00 10.00 ? 9   ALA A CA   9   ALA A CA   1 
ATOM 134  C C    . ALA A 1 9   ? 6.620  14.338  1.517  1.00 10.00 ? 9   ALA A C    9   ALA A C    1 
ATOM 135  O O    . ALA A 1 9   ? 6.701  15.521  2.121  1.00 10.00 ? 9   ALA A O    9   ALA A O    1 
ATOM 136  C CB   . ALA A 1 9   ? 4.670  12.988  2.259  1.00 10.00 ? 9   ALA A CB   9   ALA A CB   1 
ATOM 137  H H    . ALA A 1 9   ? 4.574  12.755  -0.390 1.00 10.00 ? 9   ALA A H    9   ALA A H    1 
ATOM 138  H HA   . ALA A 1 9   ? 4.559  14.918  1.371  1.00 10.00 ? 9   ALA A HA   9   ALA A HA   1 
ATOM 139  H HB1  . ALA A 1 9   ? 4.831  13.353  3.273  1.00 10.00 ? 9   ALA A HB1  9   ALA A 1HB  1 
ATOM 140  H HB2  . ALA A 1 9   ? 3.606  12.813  2.100  1.00 10.00 ? 9   ALA A HB2  9   ALA A 2HB  1 
ATOM 141  H HB3  . ALA A 1 9   ? 5.215  12.055  2.119  1.00 10.00 ? 9   ALA A HB3  9   ALA A 3HB  1 
ATOM 142  N N    . GLY A 1 10  ? 7.622  13.394  0.892  1.00 10.65 ? 10  GLY A N    10  GLY A N    1 
ATOM 143  C CA   . GLY A 1 10  ? 9.017  13.650  1.212  1.00 10.65 ? 10  GLY A CA   10  GLY A CA   1 
ATOM 144  C C    . GLY A 1 10  ? 9.501  14.940  0.550  1.00 10.65 ? 10  GLY A C    10  GLY A C    1 
ATOM 145  O O    . GLY A 1 10  ? 10.255 15.642  1.393  1.00 10.65 ? 10  GLY A O    10  GLY A O    1 
ATOM 146  H H    . GLY A 1 10  ? 7.368  12.472  0.646  1.00 10.65 ? 10  GLY A H    10  GLY A H    1 
ATOM 147  H HA2  . GLY A 1 10  ? 9.134  13.722  2.294  1.00 10.65 ? 10  GLY A HA2  10  GLY A 1HA  1 
ATOM 148  H HA3  . GLY A 1 10  ? 9.626  12.811  0.879  1.00 10.65 ? 10  GLY A HA3  10  GLY A 2HA  1 
ATOM 149  N N    . LEU A 1 11  ? 8.809  15.252  -0.750 1.00 10.21 ? 11  LEU A N    11  LEU A N    1 
ATOM 150  C CA   . LEU A 1 11  ? 9.361  16.387  -1.499 1.00 10.21 ? 11  LEU A CA   11  LEU A CA   1 
ATOM 151  C C    . LEU A 1 11  ? 9.012  17.608  -0.803 1.00 10.21 ? 11  LEU A C    11  LEU A C    1 
ATOM 152  O O    . LEU A 1 11  ? 10.076 18.446  -0.745 1.00 10.21 ? 11  LEU A O    11  LEU A O    1 
ATOM 153  C CB   . LEU A 1 11  ? 8.820  16.453  -2.933 1.00 10.21 ? 11  LEU A CB   11  LEU A CB   1 
ATOM 154  C CG   . LEU A 1 11  ? 9.235  15.298  -3.853 1.00 10.21 ? 11  LEU A CG   11  LEU A CG   1 
ATOM 155  C CD1  . LEU A 1 11  ? 8.489  15.409  -5.176 1.00 10.21 ? 11  LEU A CD1  11  LEU A CD1  1 
ATOM 156  C CD2  . LEU A 1 11  ? 10.741 15.338  -4.070 1.00 10.21 ? 11  LEU A CD2  11  LEU A CD2  1 
ATOM 157  H H    . LEU A 1 11  ? 8.334  14.561  -1.168 1.00 10.21 ? 11  LEU A H    11  LEU A H    1 
ATOM 158  H HA   . LEU A 1 11  ? 10.443 16.271  -1.555 1.00 10.21 ? 11  LEU A HA   11  LEU A HA   1 
ATOM 159  H HB2  . LEU A 1 11  ? 7.732  16.470  -2.893 1.00 10.21 ? 11  LEU A HB2  11  LEU A 1HB  1 
ATOM 160  H HB3  . LEU A 1 11  ? 9.161  17.381  -3.391 1.00 10.21 ? 11  LEU A HB3  11  LEU A 2HB  1 
ATOM 161  H HG   . LEU A 1 11  ? 8.960  14.349  -3.393 1.00 10.21 ? 11  LEU A HG   11  LEU A HG   1 
ATOM 162  H HD11 . LEU A 1 11  ? 8.784  14.588  -5.830 1.00 10.21 ? 11  LEU A HD11 11  LEU A 1HD1 1 
ATOM 163  H HD12 . LEU A 1 11  ? 7.415  15.358  -4.993 1.00 10.21 ? 11  LEU A HD12 11  LEU A 2HD1 1 
ATOM 164  H HD13 . LEU A 1 11  ? 8.732  16.358  -5.652 1.00 10.21 ? 11  LEU A HD13 11  LEU A 3HD1 1 
ATOM 165  H HD21 . LEU A 1 11  ? 11.036 14.517  -4.724 1.00 10.21 ? 11  LEU A HD21 11  LEU A 1HD2 1 
ATOM 166  H HD22 . LEU A 1 11  ? 11.017 16.286  -4.532 1.00 10.21 ? 11  LEU A HD22 11  LEU A 2HD2 1 
ATOM 167  H HD23 . LEU A 1 11  ? 11.249 15.239  -3.111 1.00 10.21 ? 11  LEU A HD23 11  LEU A 3HD2 1 
ATOM 168  N N    . LEU A 1 12  ? 7.616  17.543  -0.183 1.00 8.40  ? 12  LEU A N    12  LEU A N    1 
ATOM 169  C CA   . LEU A 1 12  ? 7.067  18.733  0.547  1.00 8.40  ? 12  LEU A CA   12  LEU A CA   1 
ATOM 170  C C    . LEU A 1 12  ? 7.832  19.044  1.783  1.00 8.40  ? 12  LEU A C    12  LEU A C    1 
ATOM 171  O O    . LEU A 1 12  ? 8.062  20.365  1.839  1.00 8.40  ? 12  LEU A O    12  LEU A O    1 
ATOM 172  C CB   . LEU A 1 12  ? 5.599  18.512  0.935  1.00 8.40  ? 12  LEU A CB   12  LEU A CB   1 
ATOM 173  C CG   . LEU A 1 12  ? 4.605  18.449  -0.231 1.00 8.40  ? 12  LEU A CG   12  LEU A CG   1 
ATOM 174  C CD1  . LEU A 1 12  ? 3.235  18.035  0.290  1.00 8.40  ? 12  LEU A CD1  12  LEU A CD1  1 
ATOM 175  C CD2  . LEU A 1 12  ? 4.541  19.805  -0.918 1.00 8.40  ? 12  LEU A CD2  12  LEU A CD2  1 
ATOM 176  H H    . LEU A 1 12  ? 7.077  16.804  -0.411 1.00 8.40  ? 12  LEU A H    12  LEU A H    1 
ATOM 177  H HA   . LEU A 1 12  ? 7.121  19.598  -0.113 1.00 8.40  ? 12  LEU A HA   12  LEU A HA   1 
ATOM 178  H HB2  . LEU A 1 12  ? 5.523  17.576  1.486  1.00 8.40  ? 12  LEU A HB2  12  LEU A 1HB  1 
ATOM 179  H HB3  . LEU A 1 12  ? 5.288  19.323  1.593  1.00 8.40  ? 12  LEU A HB3  12  LEU A 2HB  1 
ATOM 180  H HG   . LEU A 1 12  ? 4.931  17.694  -0.947 1.00 8.40  ? 12  LEU A HG   12  LEU A HG   1 
ATOM 181  H HD11 . LEU A 1 12  ? 2.529  17.990  -0.539 1.00 8.40  ? 12  LEU A HD11 12  LEU A 1HD1 1 
ATOM 182  H HD12 . LEU A 1 12  ? 3.306  17.054  0.759  1.00 8.40  ? 12  LEU A HD12 12  LEU A 2HD1 1 
ATOM 183  H HD13 . LEU A 1 12  ? 2.890  18.764  1.022  1.00 8.40  ? 12  LEU A HD13 12  LEU A 3HD1 1 
ATOM 184  H HD21 . LEU A 1 12  ? 3.835  19.760  -1.748 1.00 8.40  ? 12  LEU A HD21 12  LEU A 1HD2 1 
ATOM 185  H HD22 . LEU A 1 12  ? 4.214  20.560  -0.203 1.00 8.40  ? 12  LEU A HD22 12  LEU A 2HD2 1 
ATOM 186  H HD23 . LEU A 1 12  ? 5.529  20.068  -1.297 1.00 8.40  ? 12  LEU A HD23 12  LEU A 3HD2 1 
ATOM 187  N N    . LEU A 1 13  ? 8.313  17.822  2.560  1.00 7.45  ? 13  LEU A N    13  LEU A N    1 
ATOM 188  C CA   . LEU A 1 13  ? 9.055  18.069  3.796  1.00 7.45  ? 13  LEU A CA   13  LEU A CA   1 
ATOM 189  C C    . LEU A 1 13  ? 10.394 18.704  3.453  1.00 7.45  ? 13  LEU A C    13  LEU A C    1 
ATOM 190  O O    . LEU A 1 13  ? 10.563 19.778  4.270  1.00 7.45  ? 13  LEU A O    13  LEU A O    1 
ATOM 191  C CB   . LEU A 1 13  ? 9.273  16.764  4.573  1.00 7.45  ? 13  LEU A CB   13  LEU A CB   1 
ATOM 192  C CG   . LEU A 1 13  ? 8.014  16.136  5.185  1.00 7.45  ? 13  LEU A CG   13  LEU A CG   1 
ATOM 193  C CD1  . LEU A 1 13  ? 8.356  14.767  5.756  1.00 7.45  ? 13  LEU A CD1  13  LEU A CD1  1 
ATOM 194  C CD2  . LEU A 1 13  ? 7.460  17.056  6.263  1.00 7.45  ? 13  LEU A CD2  13  LEU A CD2  1 
ATOM 195  H H    . LEU A 1 13  ? 7.943  16.942  2.349  1.00 7.45  ? 13  LEU A H    13  LEU A H    1 
ATOM 196  H HA   . LEU A 1 13  ? 8.474  18.748  4.419  1.00 7.45  ? 13  LEU A HA   13  LEU A HA   1 
ATOM 197  H HB2  . LEU A 1 13  ? 9.717  16.030  3.903  1.00 7.45  ? 13  LEU A HB2  13  LEU A 1HB  1 
ATOM 198  H HB3  . LEU A 1 13  ? 9.976  16.956  5.384  1.00 7.45  ? 13  LEU A HB3  13  LEU A 2HB  1 
ATOM 199  H HG   . LEU A 1 13  ? 7.264  15.995  4.407  1.00 7.45  ? 13  LEU A HG   13  LEU A HG   1 
ATOM 200  H HD11 . LEU A 1 13  ? 7.462  14.320  6.191  1.00 7.45  ? 13  LEU A HD11 13  LEU A 1HD1 1 
ATOM 201  H HD12 . LEU A 1 13  ? 8.732  14.123  4.961  1.00 7.45  ? 13  LEU A HD12 13  LEU A 2HD1 1 
ATOM 202  H HD13 . LEU A 1 13  ? 9.118  14.874  6.527  1.00 7.45  ? 13  LEU A HD13 13  LEU A 3HD1 1 
ATOM 203  H HD21 . LEU A 1 13  ? 6.565  16.609  6.697  1.00 7.45  ? 13  LEU A HD21 13  LEU A 1HD2 1 
ATOM 204  H HD22 . LEU A 1 13  ? 8.210  17.196  7.042  1.00 7.45  ? 13  LEU A HD22 13  LEU A 2HD2 1 
ATOM 205  H HD23 . LEU A 1 13  ? 7.208  18.021  5.823  1.00 7.45  ? 13  LEU A HD23 13  LEU A 3HD2 1 
ATOM 206  N N    . LEU A 1 14  ? 11.073 18.212  2.182  1.00 7.78  ? 14  LEU A N    14  LEU A N    1 
ATOM 207  C CA   . LEU A 1 14  ? 12.370 18.771  1.916  1.00 7.78  ? 14  LEU A CA   14  LEU A CA   1 
ATOM 208  C C    . LEU A 1 14  ? 12.286 20.164  1.672  1.00 7.78  ? 14  LEU A C    14  LEU A C    1 
ATOM 209  O O    . LEU A 1 14  ? 13.349 20.720  2.188  1.00 7.78  ? 14  LEU A O    14  LEU A O    1 
ATOM 210  C CB   . LEU A 1 14  ? 13.032 18.105  0.703  1.00 7.78  ? 14  LEU A CB   14  LEU A CB   1 
ATOM 211  C CG   . LEU A 1 14  ? 13.479 16.652  0.904  1.00 7.78  ? 14  LEU A CG   14  LEU A CG   1 
ATOM 212  C CD1  . LEU A 1 14  ? 13.909 16.063  -0.433 1.00 7.78  ? 14  LEU A CD1  14  LEU A CD1  1 
ATOM 213  C CD2  . LEU A 1 14  ? 14.617 16.605  1.913  1.00 7.78  ? 14  LEU A CD2  14  LEU A CD2  1 
ATOM 214  H H    . LEU A 1 14  ? 10.732 17.444  1.690  1.00 7.78  ? 14  LEU A H    14  LEU A H    1 
ATOM 215  H HA   . LEU A 1 14  ? 13.005 18.601  2.785  1.00 7.78  ? 14  LEU A HA   14  LEU A HA   1 
ATOM 216  H HB2  . LEU A 1 14  ? 12.330 18.124  -0.129 1.00 7.78  ? 14  LEU A HB2  14  LEU A 1HB  1 
ATOM 217  H HB3  . LEU A 1 14  ? 13.910 18.687  0.423  1.00 7.78  ? 14  LEU A HB3  14  LEU A 2HB  1 
ATOM 218  H HG   . LEU A 1 14  ? 12.641 16.061  1.274  1.00 7.78  ? 14  LEU A HG   14  LEU A HG   1 
ATOM 219  H HD11 . LEU A 1 14  ? 14.227 15.030  -0.291 1.00 7.78  ? 14  LEU A HD11 14  LEU A 1HD1 1 
ATOM 220  H HD12 . LEU A 1 14  ? 13.071 16.091  -1.130 1.00 7.78  ? 14  LEU A HD12 14  LEU A 2HD1 1 
ATOM 221  H HD13 . LEU A 1 14  ? 14.737 16.645  -0.837 1.00 7.78  ? 14  LEU A HD13 14  LEU A 3HD1 1 
ATOM 222  H HD21 . LEU A 1 14  ? 14.935 15.572  2.056  1.00 7.78  ? 14  LEU A HD21 14  LEU A 1HD2 1 
ATOM 223  H HD22 . LEU A 1 14  ? 15.456 17.195  1.543  1.00 7.78  ? 14  LEU A HD22 14  LEU A 2HD2 1 
ATOM 224  H HD23 . LEU A 1 14  ? 14.277 17.016  2.864  1.00 7.78  ? 14  LEU A HD23 14  LEU A 3HD2 1 
ATOM 225  N N    . ALA A 1 15  ? 11.073 20.646  0.838  1.00 6.98  ? 15  ALA A N    15  ALA A N    1 
ATOM 226  C CA   . ALA A 1 15  ? 10.854 22.034  0.473  1.00 6.98  ? 15  ALA A CA   15  ALA A CA   1 
ATOM 227  C C    . ALA A 1 15  ? 10.625 22.871  1.675  1.00 6.98  ? 15  ALA A C    15  ALA A C    1 
ATOM 228  O O    . ALA A 1 15  ? 11.232 24.034  1.541  1.00 6.98  ? 15  ALA A O    15  ALA A O    1 
ATOM 229  C CB   . ALA A 1 15  ? 9.675  22.165  -0.480 1.00 6.98  ? 15  ALA A CB   15  ALA A CB   1 
ATOM 230  H H    . ALA A 1 15  ? 10.559 19.975  0.447  1.00 6.98  ? 15  ALA A H    15  ALA A H    1 
ATOM 231  H HA   . ALA A 1 15  ? 11.750 22.398  -0.028 1.00 6.98  ? 15  ALA A HA   15  ALA A HA   1 
ATOM 232  H HB1  . ALA A 1 15  ? 9.522  23.216  -0.726 1.00 6.98  ? 15  ALA A HB1  15  ALA A 1HB  1 
ATOM 233  H HB2  . ALA A 1 15  ? 9.882  21.606  -1.393 1.00 6.98  ? 15  ALA A HB2  15  ALA A 2HB  1 
ATOM 234  H HB3  . ALA A 1 15  ? 8.779  21.768  -0.007 1.00 6.98  ? 15  ALA A HB3  15  ALA A 3HB  1 
ATOM 235  N N    . ALA A 1 16  ? 9.830  22.253  2.851  1.00 6.55  ? 16  ALA A N    16  ALA A N    1 
ATOM 236  C CA   . ALA A 1 16  ? 9.577  23.086  3.983  1.00 6.55  ? 16  ALA A CA   16  ALA A CA   1 
ATOM 237  C C    . ALA A 1 16  ? 10.779 23.422  4.687  1.00 6.55  ? 16  ALA A C    16  ALA A C    1 
ATOM 238  O O    . ALA A 1 16  ? 10.727 24.648  5.137  1.00 6.55  ? 16  ALA A O    16  ALA A O    1 
ATOM 239  C CB   . ALA A 1 16  ? 8.604  22.420  4.944  1.00 6.55  ? 16  ALA A CB   16  ALA A CB   1 
ATOM 240  H H    . ALA A 1 16  ? 9.279  21.492  2.631  1.00 6.55  ? 16  ALA A H    16  ALA A H    1 
ATOM 241  H HA   . ALA A 1 16  ? 9.132  24.015  3.626  1.00 6.55  ? 16  ALA A HA   16  ALA A HA   1 
ATOM 242  H HB1  . ALA A 1 16  ? 8.443  23.067  5.806  1.00 6.55  ? 16  ALA A HB1  16  ALA A 1HB  1 
ATOM 243  H HB2  . ALA A 1 16  ? 7.654  22.246  4.439  1.00 6.55  ? 16  ALA A HB2  16  ALA A 2HB  1 
ATOM 244  H HB3  . ALA A 1 16  ? 9.016  21.469  5.278  1.00 6.55  ? 16  ALA A HB3  16  ALA A 3HB  1 
ATOM 245  N N    . GLN A 1 17  ? 11.854 22.373  4.512  1.00 5.40  ? 17  GLN A N    17  GLN A N    1 
ATOM 246  C CA   . GLN A 1 17  ? 13.280 22.559  5.024  1.00 5.40  ? 17  GLN A CA   17  GLN A CA   1 
ATOM 247  C C    . GLN A 1 17  ? 14.287 23.129  3.808  1.00 5.40  ? 17  GLN A C    17  GLN A C    1 
ATOM 248  O O    . GLN A 1 17  ? 14.165 24.269  2.868  1.00 5.40  ? 17  GLN A O    17  GLN A O    1 
ATOM 249  C CB   . GLN A 1 17  ? 13.794 21.233  5.590  1.00 5.40  ? 17  GLN A CB   17  GLN A CB   1 
ATOM 250  C CG   . GLN A 1 17  ? 12.858 20.579  6.592  1.00 5.40  ? 17  GLN A CG   17  GLN A CG   1 
ATOM 251  C CD   . GLN A 1 17  ? 12.706 21.396  7.861  1.00 5.40  ? 17  GLN A CD   17  GLN A CD   1 
ATOM 252  O OE1  . GLN A 1 17  ? 13.678 21.635  8.583  1.00 5.40  ? 17  GLN A OE1  17  GLN A OE1  1 
ATOM 253  N NE2  . GLN A 1 17  ? 11.482 21.831  8.140  1.00 5.40  ? 17  GLN A NE2  17  GLN A NE2  1 
ATOM 254  H H    . GLN A 1 17  ? 11.548 21.444  4.300  1.00 5.40  ? 17  GLN A H    17  GLN A H    1 
ATOM 255  H HA   . GLN A 1 17  ? 13.268 23.306  5.817  1.00 5.40  ? 17  GLN A HA   17  GLN A HA   1 
ATOM 256  H HB2  . GLN A 1 17  ? 13.960 20.529  4.775  1.00 5.40  ? 17  GLN A HB2  17  GLN A 1HB  1 
ATOM 257  H HB3  . GLN A 1 17  ? 14.754 21.395  6.082  1.00 5.40  ? 17  GLN A HB3  17  GLN A 2HB  1 
ATOM 258  H HG2  . GLN A 1 17  ? 11.874 20.469  6.136  1.00 5.40  ? 17  GLN A HG2  17  GLN A 1HG  1 
ATOM 259  H HG3  . GLN A 1 17  ? 13.257 19.601  6.861  1.00 5.40  ? 17  GLN A HG3  17  GLN A 2HG  1 
ATOM 260  H HE21 . GLN A 1 17  ? 11.320 22.376  8.964  1.00 5.40  ? 17  GLN A HE21 17  GLN A 1HE2 1 
ATOM 261  H HE22 . GLN A 1 17  ? 10.722 21.615  7.527  1.00 5.40  ? 17  GLN A HE22 17  GLN A 2HE2 1 
ATOM 262  N N    . PRO A 1 18  ? 15.231 23.362  4.949  1.00 5.53  ? 18  PRO A N    18  PRO A N    1 
ATOM 263  C CA   . PRO A 1 18  ? 14.456 23.942  5.832  1.00 5.53  ? 18  PRO A CA   18  PRO A CA   1 
ATOM 264  C C    . PRO A 1 18  ? 14.483 25.122  5.113  1.00 5.53  ? 18  PRO A C    18  PRO A C    1 
ATOM 265  O O    . PRO A 1 18  ? 15.737 25.321  4.765  1.00 5.53  ? 18  PRO A O    18  PRO A O    1 
ATOM 266  C CB   . PRO A 1 18  ? 15.202 23.969  7.170  1.00 5.53  ? 18  PRO A CB   18  PRO A CB   1 
ATOM 267  C CG   . PRO A 1 18  ? 16.562 24.470  6.820  1.00 5.53  ? 18  PRO A CG   18  PRO A CG   1 
ATOM 268  C CD   . PRO A 1 18  ? 16.587 24.465  5.315  1.00 5.53  ? 18  PRO A CD   18  PRO A CD   1 
ATOM 269  H HA   . PRO A 1 18  ? 13.538 23.348  5.953  1.00 5.53  ? 18  PRO A HA   18  PRO A HA   1 
ATOM 270  H 1HB  . PRO A 1 18  ? 14.677 24.624  7.881  1.00 5.53  ? 18  PRO A 1HB  18  PRO A 1HB  1 
ATOM 271  H 2HB  . PRO A 1 18  ? 15.219 22.963  7.613  1.00 5.53  ? 18  PRO A 2HB  18  PRO A 2HB  1 
ATOM 272  H 1HG  . PRO A 1 18  ? 16.719 25.473  7.243  1.00 5.53  ? 18  PRO A 1HG  18  PRO A 1HG  1 
ATOM 273  H 2HG  . PRO A 1 18  ? 17.331 23.816  7.258  1.00 5.53  ? 18  PRO A 2HG  18  PRO A 2HG  1 
ATOM 274  H 1HD  . PRO A 1 18  ? 16.436 25.489  4.942  1.00 5.53  ? 18  PRO A 1HD  18  PRO A 1HD  1 
ATOM 275  H 2HD  . PRO A 1 18  ? 17.548 24.063  4.964  1.00 5.53  ? 18  PRO A 2HD  18  PRO A 2HD  1 
ATOM 276  N N    . ALA A 1 19  ? 13.176 25.839  4.777  1.00 6.38  ? 19  ALA A N    19  ALA A N    1 
ATOM 277  C CA   . ALA A 1 19  ? 12.827 27.064  4.198  1.00 6.38  ? 19  ALA A CA   19  ALA A CA   1 
ATOM 278  C C    . ALA A 1 19  ? 13.452 27.506  2.764  1.00 6.38  ? 19  ALA A C    19  ALA A C    1 
ATOM 279  O O    . ALA A 1 19  ? 14.011 28.747  2.699  1.00 6.38  ? 19  ALA A O    19  ALA A O    1 
ATOM 280  C CB   . ALA A 1 19  ? 13.142 28.098  5.269  1.00 6.38  ? 19  ALA A CB   19  ALA A CB   1 
ATOM 281  H H    . ALA A 1 19  ? 12.342 25.394  5.038  1.00 6.38  ? 19  ALA A H    19  ALA A H    1 
ATOM 282  H HA   . ALA A 1 19  ? 11.762 27.038  3.968  1.00 6.38  ? 19  ALA A HA   19  ALA A HA   1 
ATOM 283  H HB1  . ALA A 1 19  ? 12.753 29.069  4.963  1.00 6.38  ? 19  ALA A HB1  19  ALA A 1HB  1 
ATOM 284  H HB2  . ALA A 1 19  ? 12.677 27.801  6.210  1.00 6.38  ? 19  ALA A HB2  19  ALA A 2HB  1 
ATOM 285  H HB3  . ALA A 1 19  ? 14.220 28.166  5.403  1.00 6.38  ? 19  ALA A HB3  19  ALA A 3HB  1 
ATOM 286  N N    . MET A 1 20  ? 13.169 26.524  1.642  1.00 5.24  ? 20  MET A N    20  MET A N    1 
ATOM 287  C CA   . MET A 1 20  ? 13.591 26.718  0.400  1.00 5.24  ? 20  MET A CA   20  MET A CA   1 
ATOM 288  C C    . MET A 1 20  ? 15.137 26.708  0.426  1.00 5.24  ? 20  MET A C    20  MET A C    1 
ATOM 289  O O    . MET A 1 20  ? 15.847 27.808  0.147  1.00 5.24  ? 20  MET A O    20  MET A O    1 
ATOM 290  C CB   . MET A 1 20  ? 12.998 28.024  -0.126 1.00 5.24  ? 20  MET A CB   20  MET A CB   1 
ATOM 291  C CG   . MET A 1 20  ? 11.493 27.986  -0.350 1.00 5.24  ? 20  MET A CG   20  MET A CG   1 
ATOM 292  S SD   . MET A 1 20  ? 10.817 29.596  -0.807 1.00 5.24  ? 20  MET A SD   20  MET A SD   1 
ATOM 293  C CE   . MET A 1 20  ? 11.615 29.861  -2.387 1.00 5.24  ? 20  MET A CE   20  MET A CE   1 
ATOM 294  H H    . MET A 1 20  ? 13.374 25.503  1.949  1.00 5.24  ? 20  MET A H    20  MET A H    1 
ATOM 295  H HA   . MET A 1 20  ? 13.245 25.889  -0.216 1.00 5.24  ? 20  MET A HA   20  MET A HA   1 
ATOM 296  H HB2  . MET A 1 20  ? 13.211 28.829  0.575  1.00 5.24  ? 20  MET A HB2  20  MET A 1HB  1 
ATOM 297  H HB3  . MET A 1 20  ? 13.471 28.282  -1.075 1.00 5.24  ? 20  MET A HB3  20  MET A 2HB  1 
ATOM 298  H HG2  . MET A 1 20  ? 11.261 27.277  -1.144 1.00 5.24  ? 20  MET A HG2  20  MET A 1HG  1 
ATOM 299  H HG3  . MET A 1 20  ? 10.998 27.651  0.561  1.00 5.24  ? 20  MET A HG3  20  MET A 2HG  1 
ATOM 300  H HE1  . MET A 1 20  ? 11.297 30.819  -2.799 1.00 5.24  ? 20  MET A HE1  20  MET A 1HE  1 
ATOM 301  H HE2  . MET A 1 20  ? 12.697 29.864  -2.253 1.00 5.24  ? 20  MET A HE2  20  MET A 2HE  1 
ATOM 302  H HE3  . MET A 1 20  ? 11.337 29.061  -3.074 1.00 5.24  ? 20  MET A HE3  20  MET A 3HE  1 
ATOM 303  N N    . ALA A 1 21  ? 15.599 25.330  0.745  1.00 4.06  ? 21  ALA A N    21  ALA A N    1 
ATOM 304  C CA   . ALA A 1 21  ? 17.017 24.961  0.702  1.00 4.06  ? 21  ALA A CA   21  ALA A CA   1 
ATOM 305  C C    . ALA A 1 21  ? 16.917 23.715  0.015  1.00 4.06  ? 21  ALA A C    21  ALA A C    1 
ATOM 306  O O    . ALA A 1 21  ? 15.614 23.332  -0.082 1.00 4.06  ? 21  ALA A O    21  ALA A O    1 
ATOM 307  C CB   . ALA A 1 21  ? 17.679 24.807  2.064  1.00 4.06  ? 21  ALA A CB   21  ALA A CB   1 
ATOM 308  H H    . ALA A 1 21  ? 15.088 24.577  0.933  1.00 4.06  ? 21  ALA A H    21  ALA A H    1 
ATOM 309  H HA   . ALA A 1 21  ? 17.557 25.749  0.178  1.00 4.06  ? 21  ALA A HA   21  ALA A HA   1 
ATOM 310  H HB1  . ALA A 1 21  ? 18.681 24.398  1.937  1.00 4.06  ? 21  ALA A HB1  21  ALA A 1HB  1 
ATOM 311  H HB2  . ALA A 1 21  ? 17.744 25.782  2.549  1.00 4.06  ? 21  ALA A HB2  21  ALA A 2HB  1 
ATOM 312  H HB3  . ALA A 1 21  ? 17.088 24.134  2.682  1.00 4.06  ? 21  ALA A HB3  21  ALA A 3HB  1 
ATOM 313  N N    . GLN A 1 22  ? 18.133 23.266  -0.749 1.00 4.38  ? 22  GLN A N    22  GLN A N    1 
ATOM 314  C CA   . GLN A 1 22  ? 17.997 21.874  -1.415 1.00 4.38  ? 22  GLN A CA   22  GLN A CA   1 
ATOM 315  C C    . GLN A 1 22  ? 18.915 21.580  -0.227 1.00 4.38  ? 22  GLN A C    22  GLN A C    1 
ATOM 316  O O    . GLN A 1 22  ? 19.090 22.789  0.360  1.00 4.38  ? 22  GLN A O    22  GLN A O    1 
ATOM 317  C CB   . GLN A 1 22  ? 18.568 21.648  -2.817 1.00 4.38  ? 22  GLN A CB   22  GLN A CB   1 
ATOM 318  C CG   . GLN A 1 22  ? 17.870 22.441  -3.909 1.00 4.38  ? 22  GLN A CG   22  GLN A CG   1 
ATOM 319  C CD   . GLN A 1 22  ? 16.452 21.960  -4.157 1.00 4.38  ? 22  GLN A CD   22  GLN A CD   1 
ATOM 320  O OE1  . GLN A 1 22  ? 16.225 20.787  -4.467 1.00 4.38  ? 22  GLN A OE1  22  GLN A OE1  1 
ATOM 321  N NE2  . GLN A 1 22  ? 15.490 22.865  -4.022 1.00 4.38  ? 22  GLN A NE2  22  GLN A NE2  1 
ATOM 322  H H    . GLN A 1 22  ? 19.077 23.565  -0.660 1.00 4.38  ? 22  GLN A H    22  GLN A H    1 
ATOM 323  H HA   . GLN A 1 22  ? 16.937 21.644  -1.520 1.00 4.38  ? 22  GLN A HA   22  GLN A HA   1 
ATOM 324  H 1HB  . GLN A 1 22  ? 19.624 21.918  -2.828 1.00 4.38  ? 22  GLN A 1HB  22  GLN A 1HB  1 
ATOM 325  H 2HB  . GLN A 1 22  ? 18.498 20.591  -3.072 1.00 4.38  ? 22  GLN A 2HB  22  GLN A 2HB  1 
ATOM 326  H 1HG  . GLN A 1 22  ? 17.828 23.489  -3.613 1.00 4.38  ? 22  GLN A 1HG  22  GLN A 1HG  1 
ATOM 327  H 2HG  . GLN A 1 22  ? 18.433 22.336  -4.836 1.00 4.38  ? 22  GLN A 2HG  22  GLN A 2HG  1 
ATOM 328  H 1HE2 . GLN A 1 22  ? 14.535 22.606  -4.173 1.00 4.38  ? 22  GLN A 1HE2 22  GLN A 1HE2 1 
ATOM 329  H 2HE2 . GLN A 1 22  ? 15.718 23.805  -3.769 1.00 4.38  ? 22  GLN A 2HE2 22  GLN A 2HE2 1 
ATOM 330  N N    . MET A 1 23  ? 19.214 20.170  0.408  1.00 2.39  ? 23  MET A N    23  MET A N    1 
ATOM 331  C CA   . MET A 1 23  ? 20.178 20.604  1.529  1.00 2.39  ? 23  MET A CA   23  MET A CA   1 
ATOM 332  C C    . MET A 1 23  ? 21.354 19.712  1.271  1.00 2.39  ? 23  MET A C    23  MET A C    1 
ATOM 333  O O    . MET A 1 23  ? 21.342 18.571  1.950  1.00 2.39  ? 23  MET A O    23  MET A O    1 
ATOM 334  C CB   . MET A 1 23  ? 19.627 20.412  2.940  1.00 2.39  ? 23  MET A CB   23  MET A CB   1 
ATOM 335  C CG   . MET A 1 23  ? 18.444 21.307  3.282  1.00 2.39  ? 23  MET A CG   23  MET A CG   1 
ATOM 336  S SD   . MET A 1 23  ? 17.636 20.833  4.823  1.00 2.39  ? 23  MET A SD   23  MET A SD   1 
ATOM 337  C CE   . MET A 1 23  ? 16.606 19.480  4.263  1.00 2.39  ? 23  MET A CE   23  MET A CE   1 
ATOM 338  H H    . MET A 1 23  ? 19.054 19.261  0.021  1.00 2.39  ? 23  MET A H    23  MET A H    1 
ATOM 339  H HA   . MET A 1 23  ? 20.385 21.668  1.414  1.00 2.39  ? 23  MET A HA   23  MET A HA   1 
ATOM 340  H HB2  . MET A 1 23  ? 19.310 19.377  3.068  1.00 2.39  ? 23  MET A HB2  23  MET A 1HB  1 
ATOM 341  H HB3  . MET A 1 23  ? 20.415 20.606  3.669  1.00 2.39  ? 23  MET A HB3  23  MET A 2HB  1 
ATOM 342  H HG2  . MET A 1 23  ? 18.783 22.338  3.373  1.00 2.39  ? 23  MET A HG2  23  MET A 1HG  1 
ATOM 343  H HG3  . MET A 1 23  ? 17.709 21.260  2.479  1.00 2.39  ? 23  MET A HG3  23  MET A 2HG  1 
ATOM 344  H HE1  . MET A 1 23  ? 16.041 19.079  5.105  1.00 2.39  ? 23  MET A HE1  23  MET A 1HE  1 
ATOM 345  H HE2  . MET A 1 23  ? 15.914 19.840  3.500  1.00 2.39  ? 23  MET A HE2  23  MET A 2HE  1 
ATOM 346  H HE3  . MET A 1 23  ? 17.234 18.694  3.841  1.00 2.39  ? 23  MET A HE3  23  MET A 3HE  1 
ATOM 347  N N    . GLN A 1 24  ? 22.333 20.278  0.216  1.00 2.22  ? 24  GLN A N    24  GLN A N    1 
ATOM 348  C CA   . GLN A 1 24  ? 23.432 19.254  -0.071 1.00 2.22  ? 24  GLN A CA   24  GLN A CA   1 
ATOM 349  C C    . GLN A 1 24  ? 24.736 20.098  0.080  1.00 2.22  ? 24  GLN A C    24  GLN A C    1 
ATOM 350  O O    . GLN A 1 24  ? 24.874 21.288  -0.626 1.00 2.22  ? 24  GLN A O    24  GLN A O    1 
ATOM 351  C CB   . GLN A 1 24  ? 23.324 18.625  -1.462 1.00 2.22  ? 24  GLN A CB   24  GLN A CB   1 
ATOM 352  C CG   . GLN A 1 24  ? 24.487 17.717  -1.826 1.00 2.22  ? 24  GLN A CG   24  GLN A CG   1 
ATOM 353  C CD   . GLN A 1 24  ? 24.500 16.438  -1.010 1.00 2.22  ? 24  GLN A CD   24  GLN A CD   1 
ATOM 354  O OE1  . GLN A 1 24  ? 23.564 15.636  -1.072 1.00 2.22  ? 24  GLN A OE1  24  GLN A OE1  1 
ATOM 355  N NE2  . GLN A 1 24  ? 25.563 16.240  -0.239 1.00 2.22  ? 24  GLN A NE2  24  GLN A NE2  1 
ATOM 356  H H    . GLN A 1 24  ? 22.154 21.326  -0.184 1.00 2.22  ? 24  GLN A H    24  GLN A H    1 
ATOM 357  H HA   . GLN A 1 24  ? 23.351 18.447  0.657  1.00 2.22  ? 24  GLN A HA   24  GLN A HA   1 
ATOM 358  H HB2  . GLN A 1 24  ? 22.407 18.039  -1.527 1.00 2.22  ? 24  GLN A HB2  24  GLN A 1HB  1 
ATOM 359  H HB3  . GLN A 1 24  ? 23.264 19.412  -2.214 1.00 2.22  ? 24  GLN A HB3  24  GLN A 2HB  1 
ATOM 360  H HG2  . GLN A 1 24  ? 24.409 17.449  -2.880 1.00 2.22  ? 24  GLN A HG2  24  GLN A 1HG  1 
ATOM 361  H HG3  . GLN A 1 24  ? 25.421 18.249  -1.643 1.00 2.22  ? 24  GLN A HG3  24  GLN A 2HG  1 
ATOM 362  H HE21 . GLN A 1 24  ? 25.627 15.414  0.322  1.00 2.22  ? 24  GLN A HE21 24  GLN A 1HE2 1 
ATOM 363  H HE22 . GLN A 1 24  ? 26.299 16.916  -0.219 1.00 2.22  ? 24  GLN A HE22 24  GLN A 2HE2 1 
ATOM 364  N N    . LEU A 1 25  ? 25.755 19.526  1.075  1.00 1.89  ? 25  LEU A N    25  LEU A N    1 
ATOM 365  C CA   . LEU A 1 25  ? 27.024 20.291  0.909  1.00 1.89  ? 25  LEU A CA   25  LEU A CA   1 
ATOM 366  C C    . LEU A 1 25  ? 27.979 19.438  0.057  1.00 1.89  ? 25  LEU A C    25  LEU A C    1 
ATOM 367  O O    . LEU A 1 25  ? 27.780 18.134  0.243  1.00 1.89  ? 25  LEU A O    25  LEU A O    1 
ATOM 368  C CB   . LEU A 1 25  ? 27.664 20.616  2.264  1.00 1.89  ? 25  LEU A CB   25  LEU A CB   1 
ATOM 369  C CG   . LEU A 1 25  ? 26.829 21.499  3.200  1.00 1.89  ? 25  LEU A CG   25  LEU A CG   1 
ATOM 370  C CD1  . LEU A 1 25  ? 27.568 21.684  4.518  1.00 1.89  ? 25  LEU A CD1  25  LEU A CD1  1 
ATOM 371  C CD2  . LEU A 1 25  ? 26.563 22.839  2.530  1.00 1.89  ? 25  LEU A CD2  25  LEU A CD2  1 
ATOM 372  H H    . LEU A 1 25  ? 25.578 18.791  1.724  1.00 1.89  ? 25  LEU A H    25  LEU A H    1 
ATOM 373  H HA   . LEU A 1 25  ? 26.797 21.231  0.406  1.00 1.89  ? 25  LEU A HA   25  LEU A HA   1 
ATOM 374  H HB2  . LEU A 1 25  ? 27.867 19.681  2.785  1.00 1.89  ? 25  LEU A HB2  25  LEU A 1HB  1 
ATOM 375  H HB3  . LEU A 1 25  ? 28.612 21.123  2.088  1.00 1.89  ? 25  LEU A HB3  25  LEU A 2HB  1 
ATOM 376  H HG   . LEU A 1 25  ? 25.881 21.006  3.416  1.00 1.89  ? 25  LEU A HG   25  LEU A HG   1 
ATOM 377  H HD11 . LEU A 1 25  ? 26.975 22.311  5.183  1.00 1.89  ? 25  LEU A HD11 25  LEU A 1HD1 1 
ATOM 378  H HD12 . LEU A 1 25  ? 27.728 20.711  4.985  1.00 1.89  ? 25  LEU A HD12 25  LEU A 2HD1 1 
ATOM 379  H HD13 . LEU A 1 25  ? 28.530 22.160  4.332  1.00 1.89  ? 25  LEU A HD13 25  LEU A 3HD1 1 
ATOM 380  H HD21 . LEU A 1 25  ? 25.969 23.467  3.195  1.00 1.89  ? 25  LEU A HD21 25  LEU A 1HD2 1 
ATOM 381  H HD22 . LEU A 1 25  ? 27.511 23.333  2.315  1.00 1.89  ? 25  LEU A HD22 25  LEU A 2HD2 1 
ATOM 382  H HD23 . LEU A 1 25  ? 26.018 22.679  1.599  1.00 1.89  ? 25  LEU A HD23 25  LEU A 3HD2 1 
ATOM 383  N N    . VAL A 1 26  ? 28.998 20.206  -0.814 1.00 1.69  ? 26  VAL A N    26  VAL A N    1 
ATOM 384  C CA   . VAL A 1 26  ? 29.857 19.427  -1.579 1.00 1.69  ? 26  VAL A CA   26  VAL A CA   1 
ATOM 385  C C    . VAL A 1 26  ? 31.188 18.882  -1.493 1.00 1.69  ? 26  VAL A C    26  VAL A C    1 
ATOM 386  O O    . VAL A 1 26  ? 31.095 17.545  -1.814 1.00 1.69  ? 26  VAL A O    26  VAL A O    1 
ATOM 387  C CB   . VAL A 1 26  ? 29.905 20.204  -2.908 1.00 1.69  ? 26  VAL A CB   26  VAL A CB   1 
ATOM 388  C CG1  . VAL A 1 26  ? 30.874 19.542  -3.877 1.00 1.69  ? 26  VAL A CG1  26  VAL A CG1  1 
ATOM 389  C CG2  . VAL A 1 26  ? 28.511 20.286  -3.511 1.00 1.69  ? 26  VAL A CG2  26  VAL A CG2  1 
ATOM 390  H H    . VAL A 1 26  ? 28.993 21.132  -0.814 1.00 1.69  ? 26  VAL A H    26  VAL A H    1 
ATOM 391  H HA   . VAL A 1 26  ? 29.416 18.436  -1.692 1.00 1.69  ? 26  VAL A HA   26  VAL A HA   1 
ATOM 392  H HB   . VAL A 1 26  ? 30.279 21.210  -2.717 1.00 1.69  ? 26  VAL A HB   26  VAL A HB   1 
ATOM 393  H HG11 . VAL A 1 26  ? 30.896 20.105  -4.811 1.00 1.69  ? 26  VAL A HG11 26  VAL A 1HG1 1 
ATOM 394  H HG12 . VAL A 1 26  ? 31.872 19.527  -3.440 1.00 1.69  ? 26  VAL A HG12 26  VAL A 2HG1 1 
ATOM 395  H HG13 . VAL A 1 26  ? 30.548 18.522  -4.077 1.00 1.69  ? 26  VAL A HG13 26  VAL A 3HG1 1 
ATOM 396  H HG21 . VAL A 1 26  ? 28.553 20.838  -4.450 1.00 1.69  ? 26  VAL A HG21 26  VAL A 1HG2 1 
ATOM 397  H HG22 . VAL A 1 26  ? 28.135 19.280  -3.697 1.00 1.69  ? 26  VAL A HG22 26  VAL A 2HG2 1 
ATOM 398  H HG23 . VAL A 1 26  ? 27.845 20.801  -2.818 1.00 1.69  ? 26  VAL A HG23 26  VAL A 3HG2 1 
ATOM 399  N N    . GLN A 1 27  ? 32.209 19.682  -0.755 1.00 1.79  ? 27  GLN A N    27  GLN A N    1 
ATOM 400  C CA   . GLN A 1 27  ? 33.618 19.502  -0.741 1.00 1.79  ? 27  GLN A CA   27  GLN A CA   1 
ATOM 401  C C    . GLN A 1 27  ? 33.956 18.010  -0.302 1.00 1.79  ? 27  GLN A C    27  GLN A C    1 
ATOM 402  O O    . GLN A 1 27  ? 33.261 17.260  0.226  1.00 1.79  ? 27  GLN A O    27  GLN A O    1 
ATOM 403  C CB   . GLN A 1 27  ? 34.254 20.531  0.197  1.00 1.79  ? 27  GLN A CB   27  GLN A CB   1 
ATOM 404  C CG   . GLN A 1 27  ? 34.069 20.226  1.674  1.00 1.79  ? 27  GLN A CG   27  GLN A CG   1 
ATOM 405  C CD   . GLN A 1 27  ? 32.715 20.674  2.192  1.00 1.79  ? 27  GLN A CD   27  GLN A CD   1 
ATOM 406  O OE1  . GLN A 1 27  ? 32.143 21.654  1.708  1.00 1.79  ? 27  GLN A OE1  27  GLN A OE1  1 
ATOM 407  N NE2  . GLN A 1 27  ? 32.195 19.958  3.181  1.00 1.79  ? 27  GLN A NE2  27  GLN A NE2  1 
ATOM 408  H H    . GLN A 1 27  ? 31.906 20.560  -0.369 1.00 1.79  ? 27  GLN A H    27  GLN A H    1 
ATOM 409  H HA   . GLN A 1 27  ? 33.997 19.657  -1.750 1.00 1.79  ? 27  GLN A HA   27  GLN A HA   1 
ATOM 410  H HB2  . GLN A 1 27  ? 35.324 20.593  -0.002 1.00 1.79  ? 27  GLN A HB2  27  GLN A 1HB  1 
ATOM 411  H HB3  . GLN A 1 27  ? 33.828 21.515  0.001  1.00 1.79  ? 27  GLN A HB3  27  GLN A 2HB  1 
ATOM 412  H HG2  . GLN A 1 27  ? 34.154 19.150  1.826  1.00 1.79  ? 27  GLN A HG2  27  GLN A 1HG  1 
ATOM 413  H HG3  . GLN A 1 27  ? 34.841 20.746  2.242  1.00 1.79  ? 27  GLN A HG3  27  GLN A 2HG  1 
ATOM 414  H HE21 . GLN A 1 27  ? 31.303 20.205  3.564  1.00 1.79  ? 27  GLN A HE21 27  GLN A 1HE2 1 
ATOM 415  H HE22 . GLN A 1 27  ? 32.692 19.170  3.545  1.00 1.79  ? 27  GLN A HE22 27  GLN A 2HE2 1 
ATOM 416  N N    . SER A 1 28  ? 34.912 17.382  -0.816 1.00 3.09  ? 28  SER A N    28  SER A N    1 
ATOM 417  C CA   . SER A 1 28  ? 35.151 15.999  -0.195 1.00 3.09  ? 28  SER A CA   28  SER A CA   1 
ATOM 418  C C    . SER A 1 28  ? 36.641 16.289  -0.893 1.00 3.09  ? 28  SER A C    28  SER A C    1 
ATOM 419  O O    . SER A 1 28  ? 36.885 17.331  -1.854 1.00 3.09  ? 28  SER A O    28  SER A O    1 
ATOM 420  C CB   . SER A 1 28  ? 34.337 14.836  -0.726 1.00 3.09  ? 28  SER A CB   28  SER A CB   1 
ATOM 421  O OG   . SER A 1 28  ? 34.689 14.538  -2.049 1.00 3.09  ? 28  SER A OG   28  SER A OG   1 
ATOM 422  H H    . SER A 1 28  ? 35.562 17.784  -1.496 1.00 3.09  ? 28  SER A H    28  SER A H    1 
ATOM 423  H HA   . SER A 1 28  ? 34.910 16.051  0.868  1.00 3.09  ? 28  SER A HA   28  SER A HA   1 
ATOM 424  H HB2  . SER A 1 28  ? 34.501 13.960  -0.097 1.00 3.09  ? 28  SER A HB2  28  SER A 1HB  1 
ATOM 425  H HB3  . SER A 1 28  ? 33.277 15.080  -0.675 1.00 3.09  ? 28  SER A HB3  28  SER A 2HB  1 
ATOM 426  H HG   . SER A 1 28  ? 34.233 15.183  -2.595 1.00 3.09  ? 28  SER A HG   28  SER A HG   1 
ATOM 427  N N    . GLY A 1 29  ? 37.596 15.286  -0.438 1.00 1.74  ? 29  GLY A N    29  GLY A N    1 
ATOM 428  C CA   . GLY A 1 29  ? 38.841 15.452  -1.083 1.00 1.74  ? 29  GLY A CA   29  GLY A CA   1 
ATOM 429  C C    . GLY A 1 29  ? 39.907 15.604  0.071  1.00 1.74  ? 29  GLY A C    29  GLY A C    1 
ATOM 430  O O    . GLY A 1 29  ? 39.592 15.766  1.375  1.00 1.74  ? 29  GLY A O    29  GLY A O    1 
ATOM 431  H H    . GLY A 1 29  ? 37.405 14.583  0.258  1.00 1.74  ? 29  GLY A H    29  GLY A H    1 
ATOM 432  H HA2  . GLY A 1 29  ? 39.038 14.590  -1.721 1.00 1.74  ? 29  GLY A HA2  29  GLY A 1HA  1 
ATOM 433  H HA3  . GLY A 1 29  ? 38.801 16.327  -1.731 1.00 1.74  ? 29  GLY A HA3  29  GLY A 2HA  1 
ATOM 434  N N    . THR A 1 30  ? 41.092 15.322  -0.513 1.00 1.64  ? 30  THR A N    30  THR A N    1 
ATOM 435  C CA   . THR A 1 30  ? 42.409 15.416  0.332  1.00 1.64  ? 30  THR A CA   30  THR A CA   1 
ATOM 436  C C    . THR A 1 30  ? 43.258 16.457  -0.328 1.00 1.64  ? 30  THR A C    30  THR A C    1 
ATOM 437  O O    . THR A 1 30  ? 43.386 16.261  -1.621 1.00 1.64  ? 30  THR A O    30  THR A O    1 
ATOM 438  C CB   . THR A 1 30  ? 43.203 14.099  0.414  1.00 1.64  ? 30  THR A CB   30  THR A CB   1 
ATOM 439  O OG1  . THR A 1 30  ? 42.386 13.081  1.006  1.00 1.64  ? 30  THR A OG1  30  THR A OG1  1 
ATOM 440  C CG2  . THR A 1 30  ? 44.460 14.285  1.250  1.00 1.64  ? 30  THR A CG2  30  THR A CG2  1 
ATOM 441  H H    . THR A 1 30  ? 41.144 15.184  -1.513 1.00 1.64  ? 30  THR A H    30  THR A H    1 
ATOM 442  H HA   . THR A 1 30  ? 42.145 15.688  1.354  1.00 1.64  ? 30  THR A HA   30  THR A HA   1 
ATOM 443  H HB   . THR A 1 30  ? 43.485 13.781  -0.589 1.00 1.64  ? 30  THR A HB   30  THR A HB   1 
ATOM 444  H HG1  . THR A 1 30  ? 42.946 12.378  1.345  1.00 1.64  ? 30  THR A HG1  30  THR A HG1  1 
ATOM 445  H HG21 . THR A 1 30  ? 45.009 13.345  1.297  1.00 1.64  ? 30  THR A HG21 30  THR A 1HG2 1 
ATOM 446  H HG22 . THR A 1 30  ? 45.089 15.051  0.796  1.00 1.64  ? 30  THR A HG22 30  THR A 2HG2 1 
ATOM 447  H HG23 . THR A 1 30  ? 44.184 14.594  2.258  1.00 1.64  ? 30  THR A HG23 30  THR A 3HG2 1 
ATOM 448  N N    . GLU A 1 31  ? 43.592 17.649  0.553  1.00 1.52  ? 31  GLU A N    31  GLU A N    1 
ATOM 449  C CA   . GLU A 1 31  ? 44.482 18.672  -0.070 1.00 1.52  ? 31  GLU A CA   31  GLU A CA   1 
ATOM 450  C C    . GLU A 1 31  ? 45.826 18.607  0.595  1.00 1.52  ? 31  GLU A C    31  GLU A C    1 
ATOM 451  O O    . GLU A 1 31  ? 45.765 18.823  1.901  1.00 1.52  ? 31  GLU A O    31  GLU A O    1 
ATOM 452  C CB   . GLU A 1 31  ? 43.910 20.085  0.063  1.00 1.52  ? 31  GLU A CB   31  GLU A CB   1 
ATOM 453  C CG   . GLU A 1 31  ? 42.550 20.277  -0.593 1.00 1.52  ? 31  GLU A CG   31  GLU A CG   1 
ATOM 454  C CD   . GLU A 1 31  ? 42.628 20.330  -2.094 1.00 1.52  ? 31  GLU A CD   31  GLU A CD   1 
ATOM 455  O OE1  . GLU A 1 31  ? 43.676 20.643  -2.605 1.00 1.52  ? 31  GLU A OE1  31  GLU A OE1  1 
ATOM 456  O OE2  . GLU A 1 31  ? 41.637 20.058  -2.730 1.00 1.52  ? 31  GLU A OE2  31  GLU A OE2  1 
ATOM 457  H H    . GLU A 1 31  ? 43.504 17.440  1.473  1.00 1.52  ? 31  GLU A H    31  GLU A H    1 
ATOM 458  H HA   . GLU A 1 31  ? 44.578 18.448  -1.133 1.00 1.52  ? 31  GLU A HA   31  GLU A HA   1 
ATOM 459  H HB2  . GLU A 1 31  ? 43.810 20.339  1.119  1.00 1.52  ? 31  GLU A HB2  31  GLU A 1HB  1 
ATOM 460  H HB3  . GLU A 1 31  ? 44.600 20.801  -0.382 1.00 1.52  ? 31  GLU A HB3  31  GLU A 2HB  1 
ATOM 461  H HG2  . GLU A 1 31  ? 41.899 19.453  -0.304 1.00 1.52  ? 31  GLU A HG2  31  GLU A 1HG  1 
ATOM 462  H HG3  . GLU A 1 31  ? 42.107 21.201  -0.224 1.00 1.52  ? 31  GLU A HG3  31  GLU A 2HG  1 
ATOM 463  N N    . VAL A 1 32  ? 46.929 18.345  -0.365 1.00 1.64  ? 32  VAL A N    32  VAL A N    1 
ATOM 464  C CA   . VAL A 1 32  ? 48.312 18.272  0.274  1.00 1.64  ? 32  VAL A CA   32  VAL A CA   1 
ATOM 465  C C    . VAL A 1 32  ? 48.998 19.600  -0.004 1.00 1.64  ? 32  VAL A C    32  VAL A C    1 
ATOM 466  O O    . VAL A 1 32  ? 48.879 20.003  -1.256 1.00 1.64  ? 32  VAL A O    32  VAL A O    1 
ATOM 467  C CB   . VAL A 1 32  ? 49.164 17.124  -0.299 1.00 1.64  ? 32  VAL A CB   32  VAL A CB   1 
ATOM 468  C CG1  . VAL A 1 32  ? 50.526 17.082  0.378  1.00 1.64  ? 32  VAL A CG1  32  VAL A CG1  1 
ATOM 469  C CG2  . VAL A 1 32  ? 48.434 15.801  -0.125 1.00 1.64  ? 32  VAL A CG2  32  VAL A CG2  1 
ATOM 470  H H    . VAL A 1 32  ? 46.779 18.243  -1.360 1.00 1.64  ? 32  VAL A H    32  VAL A H    1 
ATOM 471  H HA   . VAL A 1 32  ? 48.190 18.093  1.343  1.00 1.64  ? 32  VAL A HA   32  VAL A HA   1 
ATOM 472  H HB   . VAL A 1 32  ? 49.338 17.308  -1.359 1.00 1.64  ? 32  VAL A HB   32  VAL A HB   1 
ATOM 473  H HG11 . VAL A 1 32  ? 51.115 16.265  -0.039 1.00 1.64  ? 32  VAL A HG11 32  VAL A 1HG1 1 
ATOM 474  H HG12 . VAL A 1 32  ? 51.045 18.025  0.210  1.00 1.64  ? 32  VAL A HG12 32  VAL A 2HG1 1 
ATOM 475  H HG13 . VAL A 1 32  ? 50.395 16.924  1.448  1.00 1.64  ? 32  VAL A HG13 32  VAL A 3HG1 1 
ATOM 476  H HG21 . VAL A 1 32  ? 49.042 14.994  -0.534 1.00 1.64  ? 32  VAL A HG21 32  VAL A 1HG2 1 
ATOM 477  H HG22 . VAL A 1 32  ? 48.255 15.620  0.935  1.00 1.64  ? 32  VAL A HG22 32  VAL A 2HG2 1 
ATOM 478  H HG23 . VAL A 1 32  ? 47.481 15.839  -0.653 1.00 1.64  ? 32  VAL A HG23 32  VAL A 3HG2 1 
ATOM 479  N N    . LYS A 1 33  ? 49.563 20.299  1.229  1.00 1.60  ? 33  LYS A N    33  LYS A N    1 
ATOM 480  C CA   . LYS A 1 33  ? 50.108 21.605  1.054  1.00 1.60  ? 33  LYS A CA   33  LYS A CA   1 
ATOM 481  C C    . LYS A 1 33  ? 51.439 21.681  1.754  1.00 1.60  ? 33  LYS A C    33  LYS A C    1 
ATOM 482  O O    . LYS A 1 33  ? 51.715 20.638  2.583  1.00 1.60  ? 33  LYS A O    33  LYS A O    1 
ATOM 483  C CB   . LYS A 1 33  ? 49.151 22.672  1.588  1.00 1.60  ? 33  LYS A CB   33  LYS A CB   1 
ATOM 484  C CG   . LYS A 1 33  ? 47.828 22.762  0.838  1.00 1.60  ? 33  LYS A CG   33  LYS A CG   1 
ATOM 485  C CD   . LYS A 1 33  ? 48.027 23.303  -0.570 1.00 1.60  ? 33  LYS A CD   33  LYS A CD   1 
ATOM 486  C CE   . LYS A 1 33  ? 48.418 24.773  -0.549 1.00 1.60  ? 33  LYS A CE   33  LYS A CE   1 
ATOM 487  N NZ   . LYS A 1 33  ? 48.584 25.325  -1.921 1.00 1.60  ? 33  LYS A NZ   33  LYS A NZ   1 
ATOM 488  H H    . LYS A 1 33  ? 49.670 19.761  1.987  1.00 1.60  ? 33  LYS A H    33  LYS A H    1 
ATOM 489  H HA   . LYS A 1 33  ? 50.258 21.778  -0.012 1.00 1.60  ? 33  LYS A HA   33  LYS A HA   1 
ATOM 490  H HB2  . LYS A 1 33  ? 48.928 22.470  2.636  1.00 1.60  ? 33  LYS A HB2  33  LYS A 1HB  1 
ATOM 491  H HB3  . LYS A 1 33  ? 49.631 23.650  1.538  1.00 1.60  ? 33  LYS A HB3  33  LYS A 2HB  1 
ATOM 492  H HG2  . LYS A 1 33  ? 47.376 21.771  0.777  1.00 1.60  ? 33  LYS A HG2  33  LYS A 1HG  1 
ATOM 493  H HG3  . LYS A 1 33  ? 47.148 23.419  1.378  1.00 1.60  ? 33  LYS A HG3  33  LYS A 2HG  1 
ATOM 494  H HD2  . LYS A 1 33  ? 48.811 22.734  -1.072 1.00 1.60  ? 33  LYS A HD2  33  LYS A 1HD  1 
ATOM 495  H HD3  . LYS A 1 33  ? 47.102 23.192  -1.136 1.00 1.60  ? 33  LYS A HD3  33  LYS A 2HD  1 
ATOM 496  H HE2  . LYS A 1 33  ? 47.651 25.346  -0.030 1.00 1.60  ? 33  LYS A HE2  33  LYS A 1HE  1 
ATOM 497  H HE3  . LYS A 1 33  ? 49.357 24.892  -0.008 1.00 1.60  ? 33  LYS A HE3  33  LYS A 2HE  1 
ATOM 498  H HZ1  . LYS A 1 33  ? 48.844 26.300  -1.863 1.00 1.60  ? 33  LYS A HZ1  33  LYS A 1HZ  1 
ATOM 499  H HZ2  . LYS A 1 33  ? 49.308 24.812  -2.405 1.00 1.60  ? 33  LYS A HZ2  33  LYS A 2HZ  1 
ATOM 500  H HZ3  . LYS A 1 33  ? 47.714 25.238  -2.426 1.00 1.60  ? 33  LYS A HZ3  33  LYS A 3HZ  1 
ATOM 501  N N    . LYS A 1 34  ? 52.220 22.837  1.287  1.00 1.72  ? 34  LYS A N    34  LYS A N    1 
ATOM 502  C CA   . LYS A 1 34  ? 53.598 22.886  2.157  1.00 1.72  ? 34  LYS A CA   34  LYS A CA   1 
ATOM 503  C C    . LYS A 1 34  ? 53.463 23.912  3.286  1.00 1.72  ? 34  LYS A C    34  LYS A C    1 
ATOM 504  O O    . LYS A 1 34  ? 52.418 24.764  3.145  1.00 1.72  ? 34  LYS A O    34  LYS A O    1 
ATOM 505  C CB   . LYS A 1 34  ? 54.824 23.257  1.322  1.00 1.72  ? 34  LYS A CB   34  LYS A CB   1 
ATOM 506  C CG   . LYS A 1 34  ? 55.082 22.334  0.139  1.00 1.72  ? 34  LYS A CG   34  LYS A CG   1 
ATOM 507  C CD   . LYS A 1 34  ? 55.373 20.914  0.599  1.00 1.72  ? 34  LYS A CD   34  LYS A CD   1 
ATOM 508  C CE   . LYS A 1 34  ? 55.763 20.021  -0.570 1.00 1.72  ? 34  LYS A CE   34  LYS A CE   1 
ATOM 509  N NZ   . LYS A 1 34  ? 55.997 18.615  -0.142 1.00 1.72  ? 34  LYS A NZ   34  LYS A NZ   1 
ATOM 510  H H    . LYS A 1 34  ? 51.898 23.550  0.656  1.00 1.72  ? 34  LYS A H    34  LYS A H    1 
ATOM 511  H HA   . LYS A 1 34  ? 53.778 21.895  2.576  1.00 1.72  ? 34  LYS A HA   34  LYS A HA   1 
ATOM 512  H HB2  . LYS A 1 34  ? 54.708 24.271  0.937  1.00 1.72  ? 34  LYS A HB2  34  LYS A 1HB  1 
ATOM 513  H HB3  . LYS A 1 34  ? 55.712 23.247  1.954  1.00 1.72  ? 34  LYS A HB3  34  LYS A 2HB  1 
ATOM 514  H HG2  . LYS A 1 34  ? 54.208 22.324  -0.513 1.00 1.72  ? 34  LYS A HG2  34  LYS A 1HG  1 
ATOM 515  H HG3  . LYS A 1 34  ? 55.934 22.704  -0.432 1.00 1.72  ? 34  LYS A HG3  34  LYS A 2HG  1 
ATOM 516  H HD2  . LYS A 1 34  ? 56.188 20.926  1.324  1.00 1.72  ? 34  LYS A HD2  34  LYS A 1HD  1 
ATOM 517  H HD3  . LYS A 1 34  ? 54.487 20.499  1.081  1.00 1.72  ? 34  LYS A HD3  34  LYS A 2HD  1 
ATOM 518  H HE2  . LYS A 1 34  ? 54.971 20.033  -1.317 1.00 1.72  ? 34  LYS A HE2  34  LYS A 1HE  1 
ATOM 519  H HE3  . LYS A 1 34  ? 56.673 20.403  -1.031 1.00 1.72  ? 34  LYS A HE3  34  LYS A 2HE  1 
ATOM 520  H HZ1  . LYS A 1 34  ? 56.254 18.057  -0.944 1.00 1.72  ? 34  LYS A HZ1  34  LYS A 1HZ  1 
ATOM 521  H HZ2  . LYS A 1 34  ? 56.744 18.589  0.538  1.00 1.72  ? 34  LYS A HZ2  34  LYS A 2HZ  1 
ATOM 522  H HZ3  . LYS A 1 34  ? 55.154 18.243  0.271  1.00 1.72  ? 34  LYS A HZ3  34  LYS A 3HZ  1 
ATOM 523  N N    . PRO A 1 35  ? 54.357 23.598  4.451  1.00 1.65  ? 35  PRO A N    35  PRO A N    1 
ATOM 524  C CA   . PRO A 1 35  ? 54.230 24.624  5.569  1.00 1.65  ? 35  PRO A CA   35  PRO A CA   1 
ATOM 525  C C    . PRO A 1 35  ? 54.647 26.008  4.797  1.00 1.65  ? 35  PRO A C    35  PRO A C    1 
ATOM 526  O O    . PRO A 1 35  ? 55.614 25.934  3.824  1.00 1.65  ? 35  PRO A O    35  PRO A O    1 
ATOM 527  C CB   . PRO A 1 35  ? 55.241 24.180  6.630  1.00 1.65  ? 35  PRO A CB   35  PRO A CB   1 
ATOM 528  C CG   . PRO A 1 35  ? 56.269 23.421  5.862  1.00 1.65  ? 35  PRO A CG   35  PRO A CG   1 
ATOM 529  C CD   . PRO A 1 35  ? 55.479 22.665  4.827  1.00 1.65  ? 35  PRO A CD   35  PRO A CD   1 
ATOM 530  H HA   . PRO A 1 35  ? 53.211 24.588  5.980  1.00 1.65  ? 35  PRO A HA   35  PRO A HA   1 
ATOM 531  H HB2  . PRO A 1 35  ? 55.657 25.058  7.146  1.00 1.65  ? 35  PRO A HB2  35  PRO A 1HB  1 
ATOM 532  H HB3  . PRO A 1 35  ? 54.740 23.566  7.394  1.00 1.65  ? 35  PRO A HB3  35  PRO A 2HB  1 
ATOM 533  H HG2  . PRO A 1 35  ? 56.998 24.113  5.416  1.00 1.65  ? 35  PRO A HG2  35  PRO A 1HG  1 
ATOM 534  H HG3  . PRO A 1 35  ? 56.832 22.756  6.534  1.00 1.65  ? 35  PRO A HG3  35  PRO A 2HG  1 
ATOM 535  H HD2  . PRO A 1 35  ? 56.121 22.450  3.960  1.00 1.65  ? 35  PRO A HD2  35  PRO A 1HD  1 
ATOM 536  H HD3  . PRO A 1 35  ? 55.096 21.732  5.267  1.00 1.65  ? 35  PRO A HD3  35  PRO A 2HD  1 
ATOM 537  N N    . GLY A 1 36  ? 53.793 27.181  5.315  1.00 1.59  ? 36  GLY A N    36  GLY A N    1 
ATOM 538  C CA   . GLY A 1 36  ? 53.867 28.459  5.048  1.00 1.59  ? 36  GLY A CA   36  GLY A CA   1 
ATOM 539  C C    . GLY A 1 36  ? 53.008 28.808  3.858  1.00 1.59  ? 36  GLY A C    36  GLY A C    1 
ATOM 540  O O    . GLY A 1 36  ? 52.778 30.138  3.724  1.00 1.59  ? 36  GLY A O    36  GLY A O    1 
ATOM 541  H H    . GLY A 1 36  ? 53.153 26.858  5.865  1.00 1.59  ? 36  GLY A H    36  GLY A H    1 
ATOM 542  H HA2  . GLY A 1 36  ? 53.547 29.031  5.919  1.00 1.59  ? 36  GLY A HA2  36  GLY A 1HA  1 
ATOM 543  H HA3  . GLY A 1 36  ? 54.903 28.729  4.849  1.00 1.59  ? 36  GLY A HA3  36  GLY A 2HA  1 
ATOM 544  N N    . GLU A 1 37  ? 52.494 27.592  3.054  1.00 1.55  ? 37  GLU A N    37  GLU A N    1 
ATOM 545  C CA   . GLU A 1 37  ? 51.687 27.975  1.896  1.00 1.55  ? 37  GLU A CA   37  GLU A CA   1 
ATOM 546  C C    . GLU A 1 37  ? 50.214 28.377  2.371  1.00 1.55  ? 37  GLU A C    37  GLU A C    1 
ATOM 547  O O    . GLU A 1 37  ? 49.793 28.261  3.730  1.00 1.55  ? 37  GLU A O    37  GLU A O    1 
ATOM 548  C CB   . GLU A 1 37  ? 51.648 26.824  0.888  1.00 1.55  ? 37  GLU A CB   37  GLU A CB   1 
ATOM 549  C CG   . GLU A 1 37  ? 52.974 26.552  0.192  1.00 1.55  ? 37  GLU A CG   37  GLU A CG   1 
ATOM 550  C CD   . GLU A 1 37  ? 52.891 25.435  -0.810 1.00 1.55  ? 37  GLU A CD   37  GLU A CD   1 
ATOM 551  O OE1  . GLU A 1 37  ? 51.938 24.695  -0.769 1.00 1.55  ? 37  GLU A OE1  37  GLU A OE1  1 
ATOM 552  O OE2  . GLU A 1 37  ? 53.783 25.320  -1.617 1.00 1.55  ? 37  GLU A OE2  37  GLU A OE2  1 
ATOM 553  H H    . GLU A 1 37  ? 52.603 26.672  3.216  1.00 1.55  ? 37  GLU A H    37  GLU A H    1 
ATOM 554  H HA   . GLU A 1 37  ? 52.149 28.843  1.425  1.00 1.55  ? 37  GLU A HA   37  GLU A HA   1 
ATOM 555  H HB2  . GLU A 1 37  ? 51.342 25.908  1.394  1.00 1.55  ? 37  GLU A HB2  37  GLU A 1HB  1 
ATOM 556  H HB3  . GLU A 1 37  ? 50.905 27.037  0.120  1.00 1.55  ? 37  GLU A HB3  37  GLU A 2HB  1 
ATOM 557  H HG2  . GLU A 1 37  ? 53.297 27.459  -0.318 1.00 1.55  ? 37  GLU A HG2  37  GLU A 1HG  1 
ATOM 558  H HG3  . GLU A 1 37  ? 53.723 26.305  0.944  1.00 1.55  ? 37  GLU A HG3  37  GLU A 2HG  1 
ATOM 559  N N    . SER A 1 38  ? 49.499 29.076  1.204  1.00 1.38  ? 38  SER A N    38  SER A N    1 
ATOM 560  C CA   . SER A 1 38  ? 48.081 29.345  1.457  1.00 1.38  ? 38  SER A CA   38  SER A CA   1 
ATOM 561  C C    . SER A 1 38  ? 47.246 28.156  0.734  1.00 1.38  ? 38  SER A C    38  SER A C    1 
ATOM 562  O O    . SER A 1 38  ? 47.643 27.722  -0.522 1.00 1.38  ? 38  SER A O    38  SER A O    1 
ATOM 563  C CB   . SER A 1 38  ? 47.703 30.713  0.923  1.00 1.38  ? 38  SER A CB   38  SER A CB   1 
ATOM 564  O OG   . SER A 1 38  ? 46.337 30.964  1.104  1.00 1.38  ? 38  SER A OG   38  SER A OG   1 
ATOM 565  H H    . SER A 1 38  ? 49.923 29.224  0.301  1.00 1.38  ? 38  SER A H    38  SER A H    1 
ATOM 566  H HA   . SER A 1 38  ? 47.912 29.331  2.534  1.00 1.38  ? 38  SER A HA   38  SER A HA   1 
ATOM 567  H HB2  . SER A 1 38  ? 48.288 31.477  1.435  1.00 1.38  ? 38  SER A HB2  38  SER A 1HB  1 
ATOM 568  H HB3  . SER A 1 38  ? 47.948 30.770  -0.137 1.00 1.38  ? 38  SER A HB3  38  SER A 2HB  1 
ATOM 569  H HG   . SER A 1 38  ? 46.053 30.382  1.813  1.00 1.38  ? 38  SER A HG   38  SER A HG   1 
ATOM 570  N N    . LEU A 1 39  ? 46.099 27.705  1.593  1.00 1.26  ? 39  LEU A N    39  LEU A N    1 
ATOM 571  C CA   . LEU A 1 39  ? 45.216 26.749  1.125  1.00 1.26  ? 39  LEU A CA   39  LEU A CA   1 
ATOM 572  C C    . LEU A 1 39  ? 43.824 27.342  1.141  1.00 1.26  ? 39  LEU A C    39  LEU A C    1 
ATOM 573  O O    . LEU A 1 39  ? 43.358 27.910  2.004  1.00 1.26  ? 39  LEU A O    39  LEU A O    1 
ATOM 574  C CB   . LEU A 1 39  ? 45.297 25.487  1.993  1.00 1.26  ? 39  LEU A CB   39  LEU A CB   1 
ATOM 575  C CG   . LEU A 1 39  ? 44.242 24.411  1.703  1.00 1.26  ? 39  LEU A CG   39  LEU A CG   1 
ATOM 576  C CD1  . LEU A 1 39  ? 44.381 23.938  0.262  1.00 1.26  ? 39  LEU A CD1  39  LEU A CD1  1 
ATOM 577  C CD2  . LEU A 1 39  ? 44.414 23.256  2.677  1.00 1.26  ? 39  LEU A CD2  39  LEU A CD2  1 
ATOM 578  H H    . LEU A 1 39  ? 45.947 28.132  2.399  1.00 1.26  ? 39  LEU A H    39  LEU A H    1 
ATOM 579  H HA   . LEU A 1 39  ? 45.494 26.491  0.103  1.00 1.26  ? 39  LEU A HA   39  LEU A HA   1 
ATOM 580  H HB2  . LEU A 1 39  ? 46.277 25.034  1.857  1.00 1.26  ? 39  LEU A HB2  39  LEU A 1HB  1 
ATOM 581  H HB3  . LEU A 1 39  ? 45.195 25.777  3.038  1.00 1.26  ? 39  LEU A HB3  39  LEU A 2HB  1 
ATOM 582  H HG   . LEU A 1 39  ? 43.245 24.838  1.819  1.00 1.26  ? 39  LEU A HG   39  LEU A HG   1 
ATOM 583  H HD11 . LEU A 1 39  ? 43.631 23.174  0.056  1.00 1.26  ? 39  LEU A HD11 39  LEU A 1HD1 1 
ATOM 584  H HD12 . LEU A 1 39  ? 44.234 24.781  -0.413 1.00 1.26  ? 39  LEU A HD12 39  LEU A 2HD1 1 
ATOM 585  H HD13 . LEU A 1 39  ? 45.375 23.520  0.111  1.00 1.26  ? 39  LEU A HD13 39  LEU A 3HD1 1 
ATOM 586  H HD21 . LEU A 1 39  ? 43.663 22.491  2.472  1.00 1.26  ? 39  LEU A HD21 39  LEU A 1HD2 1 
ATOM 587  H HD22 . LEU A 1 39  ? 45.409 22.827  2.561  1.00 1.26  ? 39  LEU A HD22 39  LEU A 2HD2 1 
ATOM 588  H HD23 . LEU A 1 39  ? 44.292 23.619  3.698  1.00 1.26  ? 39  LEU A HD23 39  LEU A 3HD2 1 
ATOM 589  N N    . LYS A 1 40  ? 43.021 27.181  0.138  1.00 1.19  ? 40  LYS A N    40  LYS A N    1 
ATOM 590  C CA   . LYS A 1 40  ? 41.616 27.597  0.000  1.00 1.19  ? 40  LYS A CA   40  LYS A CA   1 
ATOM 591  C C    . LYS A 1 40  ? 40.813 26.207  -0.046 1.00 1.19  ? 40  LYS A C    40  LYS A C    1 
ATOM 592  O O    . LYS A 1 40  ? 41.218 25.326  -1.007 1.00 1.19  ? 40  LYS A O    40  LYS A O    1 
ATOM 593  C CB   . LYS A 1 40  ? 41.396 28.451  -1.250 1.00 1.19  ? 40  LYS A CB   40  LYS A CB   1 
ATOM 594  C CG   . LYS A 1 40  ? 42.076 29.813  -1.208 1.00 1.19  ? 40  LYS A CG   40  LYS A CG   1 
ATOM 595  C CD   . LYS A 1 40  ? 41.723 30.644  -2.433 1.00 1.19  ? 40  LYS A CD   40  LYS A CD   1 
ATOM 596  C CE   . LYS A 1 40  ? 42.382 32.014  -2.381 1.00 1.19  ? 40  LYS A CE   40  LYS A CE   1 
ATOM 597  N NZ   . LYS A 1 40  ? 42.034 32.844  -3.567 1.00 1.19  ? 40  LYS A NZ   40  LYS A NZ   1 
ATOM 598  H H    . LYS A 1 40  ? 43.399 26.712  -0.661 1.00 1.19  ? 40  LYS A H    40  LYS A H    1 
ATOM 599  H HA   . LYS A 1 40  ? 41.346 28.197  0.870  1.00 1.19  ? 40  LYS A HA   40  LYS A HA   1 
ATOM 600  H HB2  . LYS A 1 40  ? 41.768 27.918  -2.125 1.00 1.19  ? 40  LYS A HB2  40  LYS A 1HB  1 
ATOM 601  H HB3  . LYS A 1 40  ? 40.328 28.614  -1.396 1.00 1.19  ? 40  LYS A HB3  40  LYS A 2HB  1 
ATOM 602  H HG2  . LYS A 1 40  ? 41.761 30.350  -0.312 1.00 1.19  ? 40  LYS A HG2  40  LYS A 1HG  1 
ATOM 603  H HG3  . LYS A 1 40  ? 43.156 29.679  -1.170 1.00 1.19  ? 40  LYS A HG3  40  LYS A 2HG  1 
ATOM 604  H HD2  . LYS A 1 40  ? 42.053 30.124  -3.333 1.00 1.19  ? 40  LYS A HD2  40  LYS A 1HD  1 
ATOM 605  H HD3  . LYS A 1 40  ? 40.642 30.774  -2.485 1.00 1.19  ? 40  LYS A HD3  40  LYS A 2HD  1 
ATOM 606  H HE2  . LYS A 1 40  ? 42.064 32.538  -1.481 1.00 1.19  ? 40  LYS A HE2  40  LYS A 1HE  1 
ATOM 607  H HE3  . LYS A 1 40  ? 43.465 31.896  -2.342 1.00 1.19  ? 40  LYS A HE3  40  LYS A 2HE  1 
ATOM 608  H HZ1  . LYS A 1 40  ? 42.491 33.743  -3.495 1.00 1.19  ? 40  LYS A HZ1  40  LYS A 1HZ  1 
ATOM 609  H HZ2  . LYS A 1 40  ? 42.342 32.377  -4.408 1.00 1.19  ? 40  LYS A HZ2  40  LYS A 2HZ  1 
ATOM 610  H HZ3  . LYS A 1 40  ? 41.034 32.977  -3.603 1.00 1.19  ? 40  LYS A HZ3  40  LYS A 3HZ  1 
ATOM 611  N N    . ILE A 1 41  ? 39.735 26.062  1.051  1.00 1.17  ? 41  ILE A N    41  ILE A N    1 
ATOM 612  C CA   . ILE A 1 41  ? 38.827 25.102  1.024  1.00 1.17  ? 41  ILE A CA   41  ILE A CA   1 
ATOM 613  C C    . ILE A 1 41  ? 37.452 25.649  0.584  1.00 1.17  ? 41  ILE A C    41  ILE A C    1 
ATOM 614  O O    . ILE A 1 41  ? 36.972 26.713  1.276  1.00 1.17  ? 41  ILE A O    41  ILE A O    1 
ATOM 615  C CB   . ILE A 1 41  ? 38.769 24.449  2.418  1.00 1.17  ? 41  ILE A CB   41  ILE A CB   1 
ATOM 616  C CG1  . ILE A 1 41  ? 40.145 23.906  2.811  1.00 1.17  ? 41  ILE A CG1  41  ILE A CG1  1 
ATOM 617  C CG2  . ILE A 1 41  ? 37.728 23.341  2.443  1.00 1.17  ? 41  ILE A CG2  41  ILE A CG2  1 
ATOM 618  C CD1  . ILE A 1 41  ? 40.685 22.864  1.859  1.00 1.17  ? 41  ILE A CD1  41  ILE A CD1  1 
ATOM 619  H H    . ILE A 1 41  ? 39.674 26.667  1.712  1.00 1.17  ? 41  ILE A H    41  ILE A H    1 
ATOM 620  H HA   . ILE A 1 41  ? 39.130 24.360  0.286  1.00 1.17  ? 41  ILE A HA   41  ILE A HA   1 
ATOM 621  H HB   . ILE A 1 41  ? 38.503 25.201  3.160  1.00 1.17  ? 41  ILE A HB   41  ILE A HB   1 
ATOM 622  H HG12 . ILE A 1 41  ? 40.859 24.727  2.861  1.00 1.17  ? 41  ILE A HG12 41  ILE A 1HG1 1 
ATOM 623  H HG13 . ILE A 1 41  ? 40.090 23.462  3.805  1.00 1.17  ? 41  ILE A HG13 41  ILE A 2HG1 1 
ATOM 624  H HG21 . ILE A 1 41  ? 37.700 22.890  3.435  1.00 1.17  ? 41  ILE A HG21 41  ILE A 1HG2 1 
ATOM 625  H HG22 . ILE A 1 41  ? 36.749 23.755  2.205  1.00 1.17  ? 41  ILE A HG22 41  ILE A 2HG2 1 
ATOM 626  H HG23 . ILE A 1 41  ? 37.989 22.580  1.706  1.00 1.17  ? 41  ILE A HG23 41  ILE A 3HG2 1 
ATOM 627  H HD11 . ILE A 1 41  ? 41.663 22.527  2.204  1.00 1.17  ? 41  ILE A HD11 41  ILE A 1HD1 1 
ATOM 628  H HD12 . ILE A 1 41  ? 40.001 22.016  1.821  1.00 1.17  ? 41  ILE A HD12 41  ILE A 2HD1 1 
ATOM 629  H HD13 . ILE A 1 41  ? 40.782 23.297  0.864  1.00 1.17  ? 41  ILE A HD13 41  ILE A 3HD1 1 
ATOM 630  N N    . SER A 1 42  ? 36.955 25.150  -0.840 1.00 1.26  ? 42  SER A N    42  SER A N    1 
ATOM 631  C CA   . SER A 1 42  ? 35.736 25.588  -1.288 1.00 1.26  ? 42  SER A CA   42  SER A CA   1 
ATOM 632  C C    . SER A 1 42  ? 34.619 24.647  -0.792 1.00 1.26  ? 42  SER A C    42  SER A C    1 
ATOM 633  O O    . SER A 1 42  ? 34.796 23.334  -1.091 1.00 1.26  ? 42  SER A O    42  SER A O    1 
ATOM 634  C CB   . SER A 1 42  ? 35.770 25.666  -2.802 1.00 1.26  ? 42  SER A CB   42  SER A CB   1 
ATOM 635  O OG   . SER A 1 42  ? 34.501 25.954  -3.319 1.00 1.26  ? 42  SER A OG   42  SER A OG   1 
ATOM 636  H H    . SER A 1 42  ? 36.789 26.128  -0.948 1.00 1.26  ? 42  SER A H    42  SER A H    1 
ATOM 637  H HA   . SER A 1 42  ? 35.551 26.581  -0.878 1.00 1.26  ? 42  SER A HA   42  SER A HA   1 
ATOM 638  H HB2  . SER A 1 42  ? 36.475 26.437  -3.110 1.00 1.26  ? 42  SER A HB2  42  SER A 1HB  1 
ATOM 639  H HB3  . SER A 1 42  ? 36.124 24.719  -3.207 1.00 1.26  ? 42  SER A HB3  42  SER A 2HB  1 
ATOM 640  H HG   . SER A 1 42  ? 34.117 26.607  -2.730 1.00 1.26  ? 42  SER A HG   42  SER A HG   1 
ATOM 641  N N    . CYS A 1 43  ? 33.449 25.381  -0.167 1.00 1.28  ? 43  CYS A N    43  CYS A N    1 
ATOM 642  C CA   . CYS A 1 43  ? 32.339 24.696  0.305  1.00 1.28  ? 43  CYS A CA   43  CYS A CA   1 
ATOM 643  C C    . CYS A 1 43  ? 31.089 25.183  -0.502 1.00 1.28  ? 43  CYS A C    43  CYS A C    1 
ATOM 644  O O    . CYS A 1 43  ? 30.672 26.457  -0.391 1.00 1.28  ? 43  CYS A O    43  CYS A O    1 
ATOM 645  C CB   . CYS A 1 43  ? 32.174 24.945  1.804  1.00 1.28  ? 43  CYS A CB   43  CYS A CB   1 
ATOM 646  S SG   . CYS A 1 43  ? 33.695 24.733  2.760  1.00 1.28  ? 43  CYS A SG   43  CYS A SG   1 
ATOM 647  H H    . CYS A 1 43  ? 33.493 26.245  0.075  1.00 1.28  ? 43  CYS A H    43  CYS A H    1 
ATOM 648  H HA   . CYS A 1 43  ? 32.494 23.630  0.138  1.00 1.28  ? 43  CYS A HA   43  CYS A HA   1 
ATOM 649  H HB2  . CYS A 1 43  ? 31.812 25.960  1.967  1.00 1.28  ? 43  CYS A HB2  43  CYS A 1HB  1 
ATOM 650  H HB3  . CYS A 1 43  ? 31.426 24.262  2.206  1.00 1.28  ? 43  CYS A HB3  43  CYS A 2HB  1 
ATOM 651  H HG   . CYS A 1 43  ? 33.878 23.454  2.449  1.00 1.28  ? 43  CYS A HG   43  CYS A HG   1 
ATOM 652  N N    . LYS A 1 44  ? 30.640 24.210  -1.614 1.00 1.45  ? 44  LYS A N    44  LYS A N    1 
ATOM 653  C CA   . LYS A 1 44  ? 29.452 24.604  -2.283 1.00 1.45  ? 44  LYS A CA   44  LYS A CA   1 
ATOM 654  C C    . LYS A 1 44  ? 28.213 24.089  -1.530 1.00 1.45  ? 44  LYS A C    44  LYS A C    1 
ATOM 655  O O    . LYS A 1 44  ? 28.263 22.834  -1.037 1.00 1.45  ? 44  LYS A O    44  LYS A O    1 
ATOM 656  C CB   . LYS A 1 44  ? 29.473 24.093  -3.724 1.00 1.45  ? 44  LYS A CB   44  LYS A CB   1 
ATOM 657  C CG   . LYS A 1 44  ? 30.567 24.702  -4.592 1.00 1.45  ? 44  LYS A CG   44  LYS A CG   1 
ATOM 658  C CD   . LYS A 1 44  ? 30.507 24.164  -6.014 1.00 1.45  ? 44  LYS A CD   44  LYS A CD   1 
ATOM 659  C CE   . LYS A 1 44  ? 31.596 24.775  -6.883 1.00 1.45  ? 44  LYS A CE   44  LYS A CE   1 
ATOM 660  N NZ   . LYS A 1 44  ? 31.561 24.246  -8.274 1.00 1.45  ? 44  LYS A NZ   44  LYS A NZ   1 
ATOM 661  H H    . LYS A 1 44  ? 31.079 23.306  -1.742 1.00 1.45  ? 44  LYS A H    44  LYS A H    1 
ATOM 662  H HA   . LYS A 1 44  ? 29.407 25.694  -2.295 1.00 1.45  ? 44  LYS A HA   44  LYS A HA   1 
ATOM 663  H HB2  . LYS A 1 44  ? 29.609 23.011  -3.725 1.00 1.45  ? 44  LYS A HB2  44  LYS A 1HB  1 
ATOM 664  H HB3  . LYS A 1 44  ? 28.514 24.303  -4.199 1.00 1.45  ? 44  LYS A HB3  44  LYS A 2HB  1 
ATOM 665  H HG2  . LYS A 1 44  ? 30.450 25.786  -4.617 1.00 1.45  ? 44  LYS A HG2  44  LYS A 1HG  1 
ATOM 666  H HG3  . LYS A 1 44  ? 31.542 24.469  -4.165 1.00 1.45  ? 44  LYS A HG3  44  LYS A 2HG  1 
ATOM 667  H HD2  . LYS A 1 44  ? 30.631 23.080  -5.999 1.00 1.45  ? 44  LYS A HD2  44  LYS A 1HD  1 
ATOM 668  H HD3  . LYS A 1 44  ? 29.535 24.395  -6.450 1.00 1.45  ? 44  LYS A HD3  44  LYS A 2HD  1 
ATOM 669  H HE2  . LYS A 1 44  ? 31.471 25.856  -6.916 1.00 1.45  ? 44  LYS A HE2  44  LYS A 1HE  1 
ATOM 670  H HE3  . LYS A 1 44  ? 32.573 24.557  -6.450 1.00 1.45  ? 44  LYS A HE3  44  LYS A 2HE  1 
ATOM 671  H HZ1  . LYS A 1 44  ? 32.297 24.675  -8.817 1.00 1.45  ? 44  LYS A HZ1  44  LYS A 1HZ  1 
ATOM 672  H HZ2  . LYS A 1 44  ? 31.694 23.244  -8.257 1.00 1.45  ? 44  LYS A HZ2  44  LYS A 2HZ  1 
ATOM 673  H HZ3  . LYS A 1 44  ? 30.667 24.459  -8.693 1.00 1.45  ? 44  LYS A HZ3  44  LYS A 3HZ  1 
ATOM 674  N N    . GLY A 1 45  ? 27.005 25.026  -1.477 1.00 1.51  ? 45  GLY A N    45  GLY A N    1 
ATOM 675  C CA   . GLY A 1 45  ? 25.881 24.484  -0.785 1.00 1.51  ? 45  GLY A CA   45  GLY A CA   1 
ATOM 676  C C    . GLY A 1 45  ? 24.701 24.699  -1.666 1.00 1.51  ? 45  GLY A C    45  GLY A C    1 
ATOM 677  O O    . GLY A 1 45  ? 24.544 25.962  -2.017 1.00 1.51  ? 45  GLY A O    45  GLY A O    1 
ATOM 678  H H    . GLY A 1 45  ? 27.024 25.897  -1.737 1.00 1.51  ? 45  GLY A H    45  GLY A H    1 
ATOM 679  H HA2  . GLY A 1 45  ? 26.055 23.427  -0.581 1.00 1.51  ? 45  GLY A HA2  45  GLY A 1HA  1 
ATOM 680  H HA3  . GLY A 1 45  ? 25.772 24.983  0.177  1.00 1.51  ? 45  GLY A HA3  45  GLY A 2HA  1 
ATOM 681  N N    . SER A 1 46  ? 23.887 23.451  -1.992 1.00 1.79  ? 46  SER A N    46  SER A N    1 
ATOM 682  C CA   . SER A 1 46  ? 22.822 23.500  -2.920 1.00 1.79  ? 46  SER A CA   46  SER A CA   1 
ATOM 683  C C    . SER A 1 46  ? 21.625 24.010  -2.332 1.00 1.79  ? 46  SER A C    46  SER A C    1 
ATOM 684  O O    . SER A 1 46  ? 21.181 23.358  -1.227 1.00 1.79  ? 46  SER A O    46  SER A O    1 
ATOM 685  C CB   . SER A 1 46  ? 22.541 22.121  -3.487 1.00 1.79  ? 46  SER A CB   46  SER A CB   1 
ATOM 686  O OG   . SER A 1 46  ? 21.481 22.161  -4.402 1.00 1.79  ? 46  SER A OG   46  SER A OG   1 
ATOM 687  H H    . SER A 1 46  ? 24.115 22.609  -1.584 1.00 1.79  ? 46  SER A H    46  SER A H    1 
ATOM 688  H HA   . SER A 1 46  ? 23.107 24.160  -3.741 1.00 1.79  ? 46  SER A HA   46  SER A HA   1 
ATOM 689  H HB2  . SER A 1 46  ? 23.436 21.741  -3.978 1.00 1.79  ? 46  SER A HB2  46  SER A 1HB  1 
ATOM 690  H HB3  . SER A 1 46  ? 22.298 21.437  -2.674 1.00 1.79  ? 46  SER A HB3  46  SER A 2HB  1 
ATOM 691  H HG   . SER A 1 46  ? 21.884 22.161  -5.274 1.00 1.79  ? 46  SER A HG   46  SER A HG   1 
ATOM 692  N N    . GLY A 1 47  ? 21.140 25.159  -3.178 1.00 2.62  ? 47  GLY A N    47  GLY A N    1 
ATOM 693  C CA   . GLY A 1 47  ? 19.741 25.846  -3.033 1.00 2.62  ? 47  GLY A CA   47  GLY A CA   1 
ATOM 694  C C    . GLY A 1 47  ? 19.826 26.819  -1.845 1.00 2.62  ? 47  GLY A C    47  GLY A C    1 
ATOM 695  O O    . GLY A 1 47  ? 18.698 27.440  -1.365 1.00 2.62  ? 47  GLY A O    47  GLY A O    1 
ATOM 696  H H    . GLY A 1 47  ? 21.766 25.507  -3.900 1.00 2.62  ? 47  GLY A H    47  GLY A H    1 
ATOM 697  H HA2  . GLY A 1 47  ? 19.492 26.363  -3.960 1.00 2.62  ? 47  GLY A HA2  47  GLY A 1HA  1 
ATOM 698  H HA3  . GLY A 1 47  ? 18.977 25.085  -2.875 1.00 2.62  ? 47  GLY A HA3  47  GLY A 2HA  1 
ATOM 699  N N    . TYR A 1 48  ? 21.216 26.995  -1.335 1.00 3.48  ? 48  TYR A N    48  TYR A N    1 
ATOM 700  C CA   . TYR A 1 48  ? 21.068 27.781  0.026  1.00 3.48  ? 48  TYR A CA   48  TYR A CA   1 
ATOM 701  C C    . TYR A 1 48  ? 21.523 28.674  -1.155 1.00 3.48  ? 48  TYR A C    48  TYR A C    1 
ATOM 702  O O    . TYR A 1 48  ? 21.816 27.952  -2.312 1.00 3.48  ? 48  TYR A O    48  TYR A O    1 
ATOM 703  C CB   . TYR A 1 48  ? 22.008 27.535  1.209  1.00 3.48  ? 48  TYR A CB   48  TYR A CB   1 
ATOM 704  C CG   . TYR A 1 48  ? 22.095 26.085  1.629  1.00 3.48  ? 48  TYR A CG   48  TYR A CG   1 
ATOM 705  C CD1  . TYR A 1 48  ? 23.104 25.276  1.127  1.00 3.48  ? 48  TYR A CD1  48  TYR A CD1  1 
ATOM 706  C CD2  . TYR A 1 48  ? 21.165 25.563  2.516  1.00 3.48  ? 48  TYR A CD2  48  TYR A CD2  1 
ATOM 707  C CE1  . TYR A 1 48  ? 23.183 23.951  1.510  1.00 3.48  ? 48  TYR A CE1  48  TYR A CE1  1 
ATOM 708  C CE2  . TYR A 1 48  ? 21.244 24.238  2.899  1.00 3.48  ? 48  TYR A CE2  48  TYR A CE2  1 
ATOM 709  C CZ   . TYR A 1 48  ? 22.248 23.434  2.400  1.00 3.48  ? 48  TYR A CZ   48  TYR A CZ   1 
ATOM 710  O OH   . TYR A 1 48  ? 22.326 22.114  2.782  1.00 3.48  ? 48  TYR A OH   48  TYR A OH   1 
ATOM 711  H H    . TYR A 1 48  ? 22.239 26.762  -1.666 1.00 3.48  ? 48  TYR A H    48  TYR A H    1 
ATOM 712  H HA   . TYR A 1 48  ? 20.086 27.561  0.447  1.00 3.48  ? 48  TYR A HA   48  TYR A HA   1 
ATOM 713  H HD1  . TYR A 1 48  ? 23.835 25.686  0.429  1.00 3.48  ? 48  TYR A HD1  48  TYR A HD1  1 
ATOM 714  H HD2  . TYR A 1 48  ? 20.371 26.198  2.909  1.00 3.48  ? 48  TYR A HD2  48  TYR A HD2  1 
ATOM 715  H HE1  . TYR A 1 48  ? 23.976 23.316  1.116  1.00 3.48  ? 48  TYR A HE1  48  TYR A HE1  1 
ATOM 716  H HE2  . TYR A 1 48  ? 20.512 23.828  3.596  1.00 3.48  ? 48  TYR A HE2  48  TYR A HE2  1 
ATOM 717  H HH   . TYR A 1 48  ? 21.697 21.949  3.489  1.00 3.48  ? 48  TYR A HH   48  TYR A HH   1 
ATOM 718  H 1HB  . TYR A 1 48  ? 23.012 27.876  0.952  1.00 3.48  ? 48  TYR A 1HB  48  TYR A 1HB  1 
ATOM 719  H 2HB  . TYR A 1 48  ? 21.674 28.118  2.066  1.00 3.48  ? 48  TYR A 2HB  48  TYR A 2HB  1 
ATOM 720  N N    . GLY A 1 49  ? 21.174 30.075  -0.907 1.00 3.90  ? 49  GLY A N    49  GLY A N    1 
ATOM 721  C CA   . GLY A 1 49  ? 21.384 31.251  -1.643 1.00 3.90  ? 49  GLY A CA   49  GLY A CA   1 
ATOM 722  C C    . GLY A 1 49  ? 20.100 31.888  -1.256 1.00 3.90  ? 49  GLY A C    49  GLY A C    1 
ATOM 723  O O    . GLY A 1 49  ? 20.286 33.072  -0.652 1.00 3.90  ? 49  GLY A O    49  GLY A O    1 
ATOM 724  H H    . GLY A 1 49  ? 20.811 30.247  0.017  1.00 3.90  ? 49  GLY A H    49  GLY A H    1 
ATOM 725  H HA2  . GLY A 1 49  ? 22.302 31.732  -1.306 1.00 3.90  ? 49  GLY A HA2  49  GLY A 1HA  1 
ATOM 726  H HA3  . GLY A 1 49  ? 21.519 31.002  -2.695 1.00 3.90  ? 49  GLY A HA3  49  GLY A 2HA  1 
ATOM 727  N N    . PHE A 1 50  ? 18.905 30.930  -1.095 1.00 3.83  ? 50  PHE A N    50  PHE A N    1 
ATOM 728  C CA   . PHE A 1 50  ? 17.646 31.565  -0.686 1.00 3.83  ? 50  PHE A CA   50  PHE A CA   1 
ATOM 729  C C    . PHE A 1 50  ? 18.030 31.113  0.970  1.00 3.83  ? 50  PHE A C    50  PHE A C    1 
ATOM 730  O O    . PHE A 1 50  ? 18.429 32.076  1.871  1.00 3.83  ? 50  PHE A O    50  PHE A O    1 
ATOM 731  C CB   . PHE A 1 50  ? 16.388 30.948  -1.301 1.00 3.83  ? 50  PHE A CB   50  PHE A CB   1 
ATOM 732  C CG   . PHE A 1 50  ? 15.111 31.599  -0.851 1.00 3.83  ? 50  PHE A CG   50  PHE A CG   1 
ATOM 733  C CD1  . PHE A 1 50  ? 14.556 32.644  -1.576 1.00 3.83  ? 50  PHE A CD1  50  PHE A CD1  1 
ATOM 734  C CD2  . PHE A 1 50  ? 14.463 31.170  0.297  1.00 3.83  ? 50  PHE A CD2  50  PHE A CD2  1 
ATOM 735  C CE1  . PHE A 1 50  ? 13.382 33.244  -1.163 1.00 3.83  ? 50  PHE A CE1  50  PHE A CE1  1 
ATOM 736  C CE2  . PHE A 1 50  ? 13.289 31.767  0.711  1.00 3.83  ? 50  PHE A CE2  50  PHE A CE2  1 
ATOM 737  C CZ   . PHE A 1 50  ? 12.748 32.805  -0.020 1.00 3.83  ? 50  PHE A CZ   50  PHE A CZ   1 
ATOM 738  H H    . PHE A 1 50  ? 18.795 30.016  -1.308 1.00 3.83  ? 50  PHE A H    50  PHE A H    1 
ATOM 739  H HA   . PHE A 1 50  ? 17.666 32.609  -1.003 1.00 3.83  ? 50  PHE A HA   50  PHE A HA   1 
ATOM 740  H HB2  . PHE A 1 50  ? 16.442 31.019  -2.387 1.00 3.83  ? 50  PHE A HB2  50  PHE A 1HB  1 
ATOM 741  H HB3  . PHE A 1 50  ? 16.339 29.890  -1.045 1.00 3.83  ? 50  PHE A HB3  50  PHE A 2HB  1 
ATOM 742  H HD1  . PHE A 1 50  ? 15.057 32.990  -2.480 1.00 3.83  ? 50  PHE A HD1  50  PHE A HD1  1 
ATOM 743  H HD2  . PHE A 1 50  ? 14.891 30.349  0.874  1.00 3.83  ? 50  PHE A HD2  50  PHE A HD2  1 
ATOM 744  H HE1  . PHE A 1 50  ? 12.957 34.064  -1.741 1.00 3.83  ? 50  PHE A HE1  50  PHE A HE1  1 
ATOM 745  H HE2  . PHE A 1 50  ? 12.789 31.419  1.615  1.00 3.83  ? 50  PHE A HE2  50  PHE A HE2  1 
ATOM 746  H HZ   . PHE A 1 50  ? 11.823 33.278  0.307  1.00 3.83  ? 50  PHE A HZ   50  PHE A HZ   1 
ATOM 747  N N    . ILE A 1 51  ? 18.341 29.546  1.286  1.00 3.77  ? 51  ILE A N    51  ILE A N    1 
ATOM 748  C CA   . ILE A 1 51  ? 18.431 30.322  2.870  1.00 3.77  ? 51  ILE A CA   51  ILE A CA   1 
ATOM 749  C C    . ILE A 1 51  ? 19.610 31.015  3.478  1.00 3.77  ? 51  ILE A C    51  ILE A C    1 
ATOM 750  O O    . ILE A 1 51  ? 20.694 31.086  2.624  1.00 3.77  ? 51  ILE A O    51  ILE A O    1 
ATOM 751  C CB   . ILE A 1 51  ? 18.126 29.349  4.023  1.00 3.77  ? 51  ILE A CB   51  ILE A CB   1 
ATOM 752  C CG1  . ILE A 1 51  ? 19.090 28.160  3.988  1.00 3.77  ? 51  ILE A CG1  51  ILE A CG1  1 
ATOM 753  C CG2  . ILE A 1 51  ? 16.684 28.871  3.948  1.00 3.77  ? 51  ILE A CG2  51  ILE A CG2  1 
ATOM 754  C CD1  . ILE A 1 51  ? 19.043 27.298  5.228  1.00 3.77  ? 51  ILE A CD1  51  ILE A CD1  1 
ATOM 755  H H    . ILE A 1 51  ? 17.639 29.176  0.474  1.00 3.77  ? 51  ILE A H    51  ILE A H    1 
ATOM 756  H HA   . ILE A 1 51  ? 17.690 31.119  2.907  1.00 3.77  ? 51  ILE A HA   51  ILE A HA   1 
ATOM 757  H HB   . ILE A 1 51  ? 18.283 29.853  4.976  1.00 3.77  ? 51  ILE A HB   51  ILE A HB   1 
ATOM 758  H HG12 . ILE A 1 51  ? 18.862 27.532  3.127  1.00 3.77  ? 51  ILE A HG12 51  ILE A 1HG1 1 
ATOM 759  H HG13 . ILE A 1 51  ? 20.111 28.523  3.865  1.00 3.77  ? 51  ILE A HG13 51  ILE A 2HG1 1 
ATOM 760  H HG21 . ILE A 1 51  ? 16.486 28.183  4.770  1.00 3.77  ? 51  ILE A HG21 51  ILE A 1HG2 1 
ATOM 761  H HG22 . ILE A 1 51  ? 16.013 29.726  4.021  1.00 3.77  ? 51  ILE A HG22 51  ILE A 2HG2 1 
ATOM 762  H HG23 . ILE A 1 51  ? 16.519 28.359  3.000  1.00 3.77  ? 51  ILE A HG23 51  ILE A 3HG2 1 
ATOM 763  H HD11 . ILE A 1 51  ? 19.753 26.477  5.129  1.00 3.77  ? 51  ILE A HD11 51  ILE A 1HD1 1 
ATOM 764  H HD12 . ILE A 1 51  ? 19.303 27.899  6.100  1.00 3.77  ? 51  ILE A HD12 51  ILE A 2HD1 1 
ATOM 765  H HD13 . ILE A 1 51  ? 18.039 26.894  5.352  1.00 3.77  ? 51  ILE A HD13 51  ILE A 3HD1 1 
ATOM 766  N N    . THR A 1 52  ? 19.111 32.052  4.555  1.00 2.27  ? 52  THR A N    52  THR A N    1 
ATOM 767  C CA   . THR A 1 52  ? 20.063 32.928  5.209  1.00 2.27  ? 52  THR A CA   52  THR A CA   1 
ATOM 768  C C    . THR A 1 52  ? 20.442 31.507  5.910  1.00 2.27  ? 52  THR A C    52  THR A C    1 
ATOM 769  O O    . THR A 1 52  ? 19.640 30.580  6.467  1.00 2.27  ? 52  THR A O    52  THR A O    1 
ATOM 770  C CB   . THR A 1 52  ? 19.523 34.057  6.106  1.00 2.27  ? 52  THR A CB   52  THR A CB   1 
ATOM 771  O OG1  . THR A 1 52  ? 18.759 33.494  7.180  1.00 2.27  ? 52  THR A OG1  52  THR A OG1  1 
ATOM 772  C CG2  . THR A 1 52  ? 18.642 35.001  5.303  1.00 2.27  ? 52  THR A CG2  52  THR A CG2  1 
ATOM 773  H H    . THR A 1 52  ? 18.231 31.892  5.034  1.00 2.27  ? 52  THR A H    52  THR A H    1 
ATOM 774  H HA   . THR A 1 52  ? 20.646 33.439  4.443  1.00 2.27  ? 52  THR A HA   52  THR A HA   1 
ATOM 775  H HB   . THR A 1 52  ? 20.358 34.618  6.527  1.00 2.27  ? 52  THR A HB   52  THR A HB   1 
ATOM 776  H HG1  . THR A 1 52  ? 18.936 33.982  7.988  1.00 2.27  ? 52  THR A HG1  52  THR A HG1  1 
ATOM 777  H HG21 . THR A 1 52  ? 18.270 35.793  5.952  1.00 2.27  ? 52  THR A HG21 52  THR A 1HG2 1 
ATOM 778  H HG22 . THR A 1 52  ? 19.223 35.440  4.492  1.00 2.27  ? 52  THR A HG22 52  THR A 2HG2 1 
ATOM 779  H HG23 . THR A 1 52  ? 17.801 34.448  4.887  1.00 2.27  ? 52  THR A HG23 52  THR A 3HG2 1 
ATOM 780  N N    . TYR A 1 53  ? 22.017 31.268  5.525  1.00 1.68  ? 53  TYR A N    53  TYR A N    1 
ATOM 781  C CA   . TYR A 1 53  ? 22.548 30.022  5.711  1.00 1.68  ? 53  TYR A CA   53  TYR A CA   1 
ATOM 782  C C    . TYR A 1 53  ? 23.780 30.269  6.536  1.00 1.68  ? 53  TYR A C    53  TYR A C    1 
ATOM 783  O O    . TYR A 1 53  ? 24.741 30.893  5.843  1.00 1.68  ? 53  TYR A O    53  TYR A O    1 
ATOM 784  C CB   . TYR A 1 53  ? 22.848 29.334  4.378  1.00 1.68  ? 53  TYR A CB   53  TYR A CB   1 
ATOM 785  C CG   . TYR A 1 53  ? 23.176 27.863  4.509  1.00 1.68  ? 53  TYR A CG   53  TYR A CG   1 
ATOM 786  C CD1  . TYR A 1 53  ? 22.411 27.053  5.334  1.00 1.68  ? 53  TYR A CD1  53  TYR A CD1  1 
ATOM 787  C CD2  . TYR A 1 53  ? 24.244 27.326  3.805  1.00 1.68  ? 53  TYR A CD2  53  TYR A CD2  1 
ATOM 788  C CE1  . TYR A 1 53  ? 22.711 25.709  5.454  1.00 1.68  ? 53  TYR A CE1  53  TYR A CE1  1 
ATOM 789  C CE2  . TYR A 1 53  ? 24.544 25.983  3.926  1.00 1.68  ? 53  TYR A CE2  53  TYR A CE2  1 
ATOM 790  C CZ   . TYR A 1 53  ? 23.782 25.176  4.746  1.00 1.68  ? 53  TYR A CZ   53  TYR A CZ   1 
ATOM 791  O OH   . TYR A 1 53  ? 24.081 23.838  4.866  1.00 1.68  ? 53  TYR A OH   53  TYR A OH   1 
ATOM 792  H H    . TYR A 1 53  ? 22.562 32.031  5.135  1.00 1.68  ? 53  TYR A H    53  TYR A H    1 
ATOM 793  H HA   . TYR A 1 53  ? 21.821 29.413  6.251  1.00 1.68  ? 53  TYR A HA   53  TYR A HA   1 
ATOM 794  H HB2  . TYR A 1 53  ? 21.986 29.432  3.715  1.00 1.68  ? 53  TYR A HB2  53  TYR A 1HB  1 
ATOM 795  H HB3  . TYR A 1 53  ? 23.690 29.829  3.895  1.00 1.68  ? 53  TYR A HB3  53  TYR A 2HB  1 
ATOM 796  H HD1  . TYR A 1 53  ? 21.572 27.475  5.887  1.00 1.68  ? 53  TYR A HD1  53  TYR A HD1  1 
ATOM 797  H HD2  . TYR A 1 53  ? 24.846 27.963  3.158  1.00 1.68  ? 53  TYR A HD2  53  TYR A HD2  1 
ATOM 798  H HE1  . TYR A 1 53  ? 22.109 25.072  6.102  1.00 1.68  ? 53  TYR A HE1  53  TYR A HE1  1 
ATOM 799  H HE2  . TYR A 1 53  ? 25.383 25.560  3.373  1.00 1.68  ? 53  TYR A HE2  53  TYR A HE2  1 
ATOM 800  H HH   . TYR A 1 53  ? 23.375 23.395  5.343  1.00 1.68  ? 53  TYR A HH   53  TYR A HH   1 
ATOM 801  N N    . TRP A 1 54  ? 23.677 29.769  7.989  1.00 1.55  ? 54  TRP A N    54  TRP A N    1 
ATOM 802  C CA   . TRP A 1 54  ? 24.812 29.862  8.844  1.00 1.55  ? 54  TRP A CA   54  TRP A CA   1 
ATOM 803  C C    . TRP A 1 54  ? 25.793 28.799  8.407  1.00 1.55  ? 54  TRP A C    54  TRP A C    1 
ATOM 804  O O    . TRP A 1 54  ? 25.204 27.631  8.260  1.00 1.55  ? 54  TRP A O    54  TRP A O    1 
ATOM 805  C CB   . TRP A 1 54  ? 24.418 29.671  10.310 1.00 1.55  ? 54  TRP A CB   54  TRP A CB   1 
ATOM 806  C CG   . TRP A 1 54  ? 23.442 30.695  10.806 1.00 1.55  ? 54  TRP A CG   54  TRP A CG   1 
ATOM 807  C CD1  . TRP A 1 54  ? 22.155 30.862  10.391 1.00 1.55  ? 54  TRP A CD1  54  TRP A CD1  1 
ATOM 808  C CD2  . TRP A 1 54  ? 23.671 31.704  11.819 1.00 1.55  ? 54  TRP A CD2  54  TRP A CD2  1 
ATOM 809  N NE1  . TRP A 1 54  ? 21.570 31.901  11.071 1.00 1.55  ? 54  TRP A NE1  54  TRP A NE1  1 
ATOM 810  C CE2  . TRP A 1 54  ? 22.483 32.427  11.950 1.00 1.55  ? 54  TRP A CE2  54  TRP A CE2  1 
ATOM 811  C CE3  . TRP A 1 54  ? 24.773 32.046  12.613 1.00 1.55  ? 54  TRP A CE3  54  TRP A CE3  1 
ATOM 812  C CZ2  . TRP A 1 54  ? 22.358 33.478  12.845 1.00 1.55  ? 54  TRP A CZ2  54  TRP A CZ2  1 
ATOM 813  C CZ3  . TRP A 1 54  ? 24.648 33.099  13.511 1.00 1.55  ? 54  TRP A CZ3  54  TRP A CZ3  1 
ATOM 814  C CH2  . TRP A 1 54  ? 23.471 33.796  13.624 1.00 1.55  ? 54  TRP A CH2  54  TRP A CH2  1 
ATOM 815  H H    . TRP A 1 54  ? 22.905 29.246  8.235  1.00 1.55  ? 54  TRP A H    54  TRP A H    1 
ATOM 816  H HA   . TRP A 1 54  ? 25.248 30.855  8.734  1.00 1.55  ? 54  TRP A HA   54  TRP A HA   1 
ATOM 817  H HB2  . TRP A 1 54  ? 23.976 28.684  10.442 1.00 1.55  ? 54  TRP A HB2  54  TRP A 1HB  1 
ATOM 818  H HB3  . TRP A 1 54  ? 25.310 29.717  10.935 1.00 1.55  ? 54  TRP A HB3  54  TRP A 2HB  1 
ATOM 819  H HD1  . TRP A 1 54  ? 21.663 30.258  9.630  1.00 1.55  ? 54  TRP A HD1  54  TRP A HD1  1 
ATOM 820  H HE1  . TRP A 1 54  ? 20.622 32.226  10.946 1.00 1.55  ? 54  TRP A HE1  54  TRP A HE1  1 
ATOM 821  H HE3  . TRP A 1 54  ? 25.709 31.494  12.530 1.00 1.55  ? 54  TRP A HE3  54  TRP A HE3  1 
ATOM 822  H HZ2  . TRP A 1 54  ? 21.432 34.044  12.949 1.00 1.55  ? 54  TRP A HZ2  54  TRP A HZ2  1 
ATOM 823  H HZ3  . TRP A 1 54  ? 25.510 33.359  14.125 1.00 1.55  ? 54  TRP A HZ3  54  TRP A HZ3  1 
ATOM 824  H HH2  . TRP A 1 54  ? 23.407 34.617  14.338 1.00 1.55  ? 54  TRP A HH2  54  TRP A HH2  1 
ATOM 825  N N    . ILE A 1 55  ? 27.216 29.325  8.037  1.00 1.33  ? 55  ILE A N    55  ILE A N    1 
ATOM 826  C CA   . ILE A 1 55  ? 28.201 28.355  7.700  1.00 1.33  ? 55  ILE A CA   55  ILE A CA   1 
ATOM 827  C C    . ILE A 1 55  ? 29.303 28.321  8.647  1.00 1.33  ? 55  ILE A C    55  ILE A C    1 
ATOM 828  O O    . ILE A 1 55  ? 29.928 29.472  8.745  1.00 1.33  ? 55  ILE A O    55  ILE A O    1 
ATOM 829  C CB   . ILE A 1 55  ? 28.770 28.614  6.293  1.00 1.33  ? 55  ILE A CB   55  ILE A CB   1 
ATOM 830  C CG1  . ILE A 1 55  ? 27.636 28.763  5.276  1.00 1.33  ? 55  ILE A CG1  55  ILE A CG1  1 
ATOM 831  C CG2  . ILE A 1 55  ? 29.710 27.490  5.885  1.00 1.33  ? 55  ILE A CG2  55  ILE A CG2  1 
ATOM 832  C CD1  . ILE A 1 55  ? 27.375 30.192  4.857  1.00 1.33  ? 55  ILE A CD1  55  ILE A CD1  1 
ATOM 833  H H    . ILE A 1 55  ? 27.448 30.193  8.225  1.00 1.33  ? 55  ILE A H    55  ILE A H    1 
ATOM 834  H HA   . ILE A 1 55  ? 27.733 27.371  7.706  1.00 1.33  ? 55  ILE A HA   55  ILE A HA   1 
ATOM 835  H HB   . ILE A 1 55  ? 29.321 29.554  6.291  1.00 1.33  ? 55  ILE A HB   55  ILE A HB   1 
ATOM 836  H HG12 . ILE A 1 55  ? 27.868 28.182  4.384  1.00 1.33  ? 55  ILE A HG12 55  ILE A 1HG1 1 
ATOM 837  H HG13 . ILE A 1 55  ? 26.714 28.359  5.698  1.00 1.33  ? 55  ILE A HG13 55  ILE A 2HG1 1 
ATOM 838  H HG21 . ILE A 1 55  ? 30.104 27.688  4.888  1.00 1.33  ? 55  ILE A HG21 55  ILE A 1HG2 1 
ATOM 839  H HG22 . ILE A 1 55  ? 30.535 27.429  6.594  1.00 1.33  ? 55  ILE A HG22 55  ILE A 2HG2 1 
ATOM 840  H HG23 . ILE A 1 55  ? 29.167 26.545  5.879  1.00 1.33  ? 55  ILE A HG23 55  ILE A 3HG2 1 
ATOM 841  H HD11 . ILE A 1 55  ? 26.557 30.216  4.137  1.00 1.33  ? 55  ILE A HD11 55  ILE A 1HD1 1 
ATOM 842  H HD12 . ILE A 1 55  ? 27.106 30.784  5.732  1.00 1.33  ? 55  ILE A HD12 55  ILE A 2HD1 1 
ATOM 843  H HD13 . ILE A 1 55  ? 28.273 30.606  4.401  1.00 1.33  ? 55  ILE A HD13 55  ILE A 3HD1 1 
ATOM 844  N N    . GLY A 1 56  ? 29.464 26.986  9.419  1.00 1.32  ? 56  GLY A N    56  GLY A N    1 
ATOM 845  C CA   . GLY A 1 56  ? 30.595 26.956  10.431 1.00 1.32  ? 56  GLY A CA   56  GLY A CA   1 
ATOM 846  C C    . GLY A 1 56  ? 31.633 26.001  9.682  1.00 1.32  ? 56  GLY A C    56  GLY A C    1 
ATOM 847  O O    . GLY A 1 56  ? 31.440 25.025  8.994  1.00 1.32  ? 56  GLY A O    56  GLY A O    1 
ATOM 848  H H    . GLY A 1 56  ? 29.024 26.238  9.087  1.00 1.32  ? 56  GLY A H    56  GLY A H    1 
ATOM 849  H HA2  . GLY A 1 56  ? 30.950 27.971  10.610 1.00 1.32  ? 56  GLY A HA2  56  GLY A 1HA  1 
ATOM 850  H HA3  . GLY A 1 56  ? 30.223 26.574  11.382 1.00 1.32  ? 56  GLY A HA3  56  GLY A 2HA  1 
ATOM 851  N N    . TRP A 1 57  ? 32.865 26.170  10.005 1.00 1.25  ? 57  TRP A N    57  TRP A N    1 
ATOM 852  C CA   . TRP A 1 57  ? 34.025 25.331  9.651  1.00 1.25  ? 57  TRP A CA   57  TRP A CA   1 
ATOM 853  C C    . TRP A 1 57  ? 34.516 24.777  11.012 1.00 1.25  ? 57  TRP A C    57  TRP A C    1 
ATOM 854  O O    . TRP A 1 57  ? 34.643 25.673  11.957 1.00 1.25  ? 57  TRP A O    57  TRP A O    1 
ATOM 855  C CB   . TRP A 1 57  ? 35.121 26.127  8.940  1.00 1.25  ? 57  TRP A CB   57  TRP A CB   1 
ATOM 856  C CG   . TRP A 1 57  ? 34.770 26.505  7.533  1.00 1.25  ? 57  TRP A CG   57  TRP A CG   1 
ATOM 857  C CD1  . TRP A 1 57  ? 35.209 25.900  6.393  1.00 1.25  ? 57  TRP A CD1  57  TRP A CD1  1 
ATOM 858  C CD2  . TRP A 1 57  ? 33.899 27.581  7.107  1.00 1.25  ? 57  TRP A CD2  57  TRP A CD2  1 
ATOM 859  N NE1  . TRP A 1 57  ? 34.675 26.523  5.292  1.00 1.25  ? 57  TRP A NE1  57  TRP A NE1  1 
ATOM 860  C CE2  . TRP A 1 57  ? 33.870 27.553  5.710  1.00 1.25  ? 57  TRP A CE2  57  TRP A CE2  1 
ATOM 861  C CE3  . TRP A 1 57  ? 33.153 28.550  7.789  1.00 1.25  ? 57  TRP A CE3  57  TRP A CE3  1 
ATOM 862  C CZ2  . TRP A 1 57  ? 33.124 28.459  4.973  1.00 1.25  ? 57  TRP A CZ2  57  TRP A CZ2  1 
ATOM 863  C CZ3  . TRP A 1 57  ? 32.404 29.458  7.050  1.00 1.25  ? 57  TRP A CZ3  57  TRP A CZ3  1 
ATOM 864  C CH2  . TRP A 1 57  ? 32.390 29.413  5.679  1.00 1.25  ? 57  TRP A CH2  57  TRP A CH2  1 
ATOM 865  H H    . TRP A 1 57  ? 33.040 26.949  10.451 1.00 1.25  ? 57  TRP A H    57  TRP A H    1 
ATOM 866  H HA   . TRP A 1 57  ? 33.690 24.547  8.971  1.00 1.25  ? 57  TRP A HA   57  TRP A HA   1 
ATOM 867  H HB2  . TRP A 1 57  ? 35.328 27.040  9.499  1.00 1.25  ? 57  TRP A HB2  57  TRP A 1HB  1 
ATOM 868  H HB3  . TRP A 1 57  ? 36.040 25.541  8.919  1.00 1.25  ? 57  TRP A HB3  57  TRP A 2HB  1 
ATOM 869  H HD1  . TRP A 1 57  ? 35.884 25.047  6.361  1.00 1.25  ? 57  TRP A HD1  57  TRP A HD1  1 
ATOM 870  H HE1  . TRP A 1 57  ? 34.847 26.267  4.330  1.00 1.25  ? 57  TRP A HE1  57  TRP A HE1  1 
ATOM 871  H HE3  . TRP A 1 57  ? 33.158 28.588  8.877  1.00 1.25  ? 57  TRP A HE3  57  TRP A HE3  1 
ATOM 872  H HZ2  . TRP A 1 57  ? 33.100 28.440  3.884  1.00 1.25  ? 57  TRP A HZ2  57  TRP A HZ2  1 
ATOM 873  H HZ3  . TRP A 1 57  ? 31.826 30.210  7.588  1.00 1.25  ? 57  TRP A HZ3  57  TRP A HZ3  1 
ATOM 874  H HH2  . TRP A 1 57  ? 31.791 30.140  5.130  1.00 1.25  ? 57  TRP A HH2  57  TRP A HH2  1 
ATOM 875  N N    . VAL A 1 58  ? 34.762 23.306  11.084 1.00 1.41  ? 58  VAL A N    58  VAL A N    1 
ATOM 876  C CA   . VAL A 1 58  ? 35.109 22.646  12.217 1.00 1.41  ? 58  VAL A CA   58  VAL A CA   1 
ATOM 877  C C    . VAL A 1 58  ? 36.360 21.754  11.977 1.00 1.41  ? 58  VAL A C    58  VAL A C    1 
ATOM 878  O O    . VAL A 1 58  ? 36.400 21.244  10.786 1.00 1.41  ? 58  VAL A O    58  VAL A O    1 
ATOM 879  C CB   . VAL A 1 58  ? 33.902 21.809  12.680 1.00 1.41  ? 58  VAL A CB   58  VAL A CB   1 
ATOM 880  C CG1  . VAL A 1 58  ? 34.238 21.050  13.955 1.00 1.41  ? 58  VAL A CG1  58  VAL A CG1  1 
ATOM 881  C CG2  . VAL A 1 58  ? 32.696 22.712  12.891 1.00 1.41  ? 58  VAL A CG2  58  VAL A CG2  1 
ATOM 882  H H    . VAL A 1 58  ? 34.655 22.796  10.342 1.00 1.41  ? 58  VAL A H    58  VAL A H    1 
ATOM 883  H HA   . VAL A 1 58  ? 35.362 23.380  12.982 1.00 1.41  ? 58  VAL A HA   58  VAL A HA   1 
ATOM 884  H HB   . VAL A 1 58  ? 33.672 21.066  11.916 1.00 1.41  ? 58  VAL A HB   58  VAL A HB   1 
ATOM 885  H HG11 . VAL A 1 58  ? 33.373 20.464  14.268 1.00 1.41  ? 58  VAL A HG11 58  VAL A 1HG1 1 
ATOM 886  H HG12 . VAL A 1 58  ? 35.080 20.384  13.771 1.00 1.41  ? 58  VAL A HG12 58  VAL A 2HG1 1 
ATOM 887  H HG13 . VAL A 1 58  ? 34.499 21.758  14.742 1.00 1.41  ? 58  VAL A HG13 58  VAL A 3HG1 1 
ATOM 888  H HG21 . VAL A 1 58  ? 31.846 22.114  13.217 1.00 1.41  ? 58  VAL A HG21 58  VAL A 1HG2 1 
ATOM 889  H HG22 . VAL A 1 58  ? 32.929 23.458  13.651 1.00 1.41  ? 58  VAL A HG22 58  VAL A 2HG2 1 
ATOM 890  H HG23 . VAL A 1 58  ? 32.449 23.213  11.955 1.00 1.41  ? 58  VAL A HG23 58  VAL A 3HG2 1 
ATOM 891  N N    . ARG A 1 59  ? 37.501 21.819  12.983 1.00 1.49  ? 59  ARG A N    59  ARG A N    1 
ATOM 892  C CA   . ARG A 1 59  ? 38.535 20.974  12.856 1.00 1.49  ? 59  ARG A CA   59  ARG A CA   1 
ATOM 893  C C    . ARG A 1 59  ? 38.272 19.717  13.700 1.00 1.49  ? 59  ARG A C    59  ARG A C    1 
ATOM 894  O O    . ARG A 1 59  ? 37.703 19.867  14.923 1.00 1.49  ? 59  ARG A O    59  ARG A O    1 
ATOM 895  C CB   . ARG A 1 59  ? 39.813 21.682  13.281 1.00 1.49  ? 59  ARG A CB   59  ARG A CB   1 
ATOM 896  C CG   . ARG A 1 59  ? 41.075 20.841  13.174 1.00 1.49  ? 59  ARG A CG   59  ARG A CG   1 
ATOM 897  C CD   . ARG A 1 59  ? 42.292 21.636  13.479 1.00 1.49  ? 59  ARG A CD   59  ARG A CD   1 
ATOM 898  N NE   . ARG A 1 59  ? 42.387 21.962  14.893 1.00 1.49  ? 59  ARG A NE   59  ARG A NE   1 
ATOM 899  C CZ   . ARG A 1 59  ? 43.515 22.361  15.512 1.00 1.49  ? 59  ARG A CZ   59  ARG A CZ   1 
ATOM 900  N NH1  . ARG A 1 59  ? 44.633 22.478  14.831 1.00 1.49  ? 59  ARG A NH1  59  ARG A NH1  1 
ATOM 901  N NH2  . ARG A 1 59  ? 43.498 22.635  16.805 1.00 1.49  ? 59  ARG A NH2  59  ARG A NH2  1 
ATOM 902  H H    . ARG A 1 59  ? 37.281 22.175  13.787 1.00 1.49  ? 59  ARG A H    59  ARG A H    1 
ATOM 903  H HA   . ARG A 1 59  ? 38.616 20.682  11.808 1.00 1.49  ? 59  ARG A HA   59  ARG A HA   1 
ATOM 904  H HB2  . ARG A 1 59  ? 39.957 22.571  12.668 1.00 1.49  ? 59  ARG A HB2  59  ARG A 1HB  1 
ATOM 905  H HB3  . ARG A 1 59  ? 39.721 22.009  14.316 1.00 1.49  ? 59  ARG A HB3  59  ARG A 2HB  1 
ATOM 906  H HG2  . ARG A 1 59  ? 41.021 20.012  13.881 1.00 1.49  ? 59  ARG A HG2  59  ARG A 1HG  1 
ATOM 907  H HG3  . ARG A 1 59  ? 41.167 20.448  12.161 1.00 1.49  ? 59  ARG A HG3  59  ARG A 2HG  1 
ATOM 908  H HD2  . ARG A 1 59  ? 43.178 21.066  13.201 1.00 1.49  ? 59  ARG A HD2  59  ARG A 1HD  1 
ATOM 909  H HD3  . ARG A 1 59  ? 42.269 22.568  12.916 1.00 1.49  ? 59  ARG A HD3  59  ARG A 2HD  1 
ATOM 910  H HE   . ARG A 1 59  ? 41.547 21.884  15.451 1.00 1.49  ? 59  ARG A HE   59  ARG A HE   1 
ATOM 911  H HH11 . ARG A 1 59  ? 44.646 22.268  13.842 1.00 1.49  ? 59  ARG A HH11 59  ARG A 1HH1 1 
ATOM 912  H HH12 . ARG A 1 59  ? 45.479 22.777  15.295 1.00 1.49  ? 59  ARG A HH12 59  ARG A 2HH1 1 
ATOM 913  H HH21 . ARG A 1 59  ? 42.638 22.545  17.330 1.00 1.49  ? 59  ARG A HH21 59  ARG A 1HH2 1 
ATOM 914  H HH22 . ARG A 1 59  ? 44.343 22.933  17.269 1.00 1.49  ? 59  ARG A HH22 59  ARG A 2HH2 1 
ATOM 915  N N    . GLN A 1 60  ? 38.624 18.427  12.972 1.00 1.71  ? 60  GLN A N    60  GLN A N    1 
ATOM 916  C CA   . GLN A 1 60  ? 38.570 17.208  13.692 1.00 1.71  ? 60  GLN A CA   60  GLN A CA   1 
ATOM 917  C C    . GLN A 1 60  ? 39.975 16.735  13.878 1.00 1.71  ? 60  GLN A C    60  GLN A C    1 
ATOM 918  O O    . GLN A 1 60  ? 40.736 16.496  12.736 1.00 1.71  ? 60  GLN A O    60  GLN A O    1 
ATOM 919  C CB   . GLN A 1 60  ? 37.729 16.163  12.955 1.00 1.71  ? 60  GLN A CB   60  GLN A CB   1 
ATOM 920  C CG   . GLN A 1 60  ? 37.562 14.854  13.709 1.00 1.71  ? 60  GLN A CG   60  GLN A CG   1 
ATOM 921  C CD   . GLN A 1 60  ? 36.629 13.892  12.999 1.00 1.71  ? 60  GLN A CD   60  GLN A CD   1 
ATOM 922  O OE1  . GLN A 1 60  ? 36.837 13.553  11.830 1.00 1.71  ? 60  GLN A OE1  60  GLN A OE1  1 
ATOM 923  N NE2  . GLN A 1 60  ? 35.595 13.445  13.701 1.00 1.71  ? 60  GLN A NE2  60  GLN A NE2  1 
ATOM 924  H H    . GLN A 1 60  ? 38.945 18.449  12.091 1.00 1.71  ? 60  GLN A H    60  GLN A H    1 
ATOM 925  H HA   . GLN A 1 60  ? 38.106 17.399  14.660 1.00 1.71  ? 60  GLN A HA   60  GLN A HA   1 
ATOM 926  H HB2  . GLN A 1 60  ? 36.736 16.567  12.759 1.00 1.71  ? 60  GLN A HB2  60  GLN A 1HB  1 
ATOM 927  H HB3  . GLN A 1 60  ? 38.188 15.940  11.992 1.00 1.71  ? 60  GLN A HB3  60  GLN A 2HB  1 
ATOM 928  H HG2  . GLN A 1 60  ? 38.536 14.377  13.808 1.00 1.71  ? 60  GLN A HG2  60  GLN A 1HG  1 
ATOM 929  H HG3  . GLN A 1 60  ? 37.148 15.066  14.696 1.00 1.71  ? 60  GLN A HG3  60  GLN A 2HG  1 
ATOM 930  H HE21 . GLN A 1 60  ? 34.945 12.807  13.285 1.00 1.71  ? 60  GLN A HE21 60  GLN A 1HE2 1 
ATOM 931  H HE22 . GLN A 1 60  ? 35.464 13.745  14.646 1.00 1.71  ? 60  GLN A HE22 60  GLN A 2HE2 1 
ATOM 932  N N    . MET A 1 61  ? 40.396 16.889  15.320 1.00 1.87  ? 61  MET A N    61  MET A N    1 
ATOM 933  C CA   . MET A 1 61  ? 41.788 16.437  15.716 1.00 1.87  ? 61  MET A CA   61  MET A CA   1 
ATOM 934  C C    . MET A 1 61  ? 41.657 15.074  16.241 1.00 1.87  ? 61  MET A C    61  MET A C    1 
ATOM 935  O O    . MET A 1 61  ? 40.625 14.916  17.027 1.00 1.87  ? 61  MET A O    61  MET A O    1 
ATOM 936  C CB   . MET A 1 61  ? 42.434 17.340  16.765 1.00 1.87  ? 61  MET A CB   61  MET A CB   1 
ATOM 937  C CG   . MET A 1 61  ? 42.719 18.757  16.287 1.00 1.87  ? 61  MET A CG   61  MET A CG   1 
ATOM 938  S SD   . MET A 1 61  ? 43.844 18.802  14.878 1.00 1.87  ? 61  MET A SD   61  MET A SD   1 
ATOM 939  C CE   . MET A 1 61  ? 45.363 18.236  15.639 1.00 1.87  ? 61  MET A CE   61  MET A CE   1 
ATOM 940  H H    . MET A 1 61  ? 39.582 17.035  16.111 1.00 1.87  ? 61  MET A H    61  MET A H    1 
ATOM 941  H HA   . MET A 1 61  ? 42.424 16.461  14.830 1.00 1.87  ? 61  MET A HA   61  MET A HA   1 
ATOM 942  H HB2  . MET A 1 61  ? 41.785 17.406  17.637 1.00 1.87  ? 61  MET A HB2  61  MET A 1HB  1 
ATOM 943  H HB3  . MET A 1 61  ? 43.378 16.901  17.092 1.00 1.87  ? 61  MET A HB3  61  MET A 2HB  1 
ATOM 944  H HG2  . MET A 1 61  ? 41.786 19.238  15.999 1.00 1.87  ? 61  MET A HG2  61  MET A 1HG  1 
ATOM 945  H HG3  . MET A 1 61  ? 43.162 19.333  17.100 1.00 1.87  ? 61  MET A HG3  61  MET A 2HG  1 
ATOM 946  H HE1  . MET A 1 61  ? 46.157 18.210  14.892 1.00 1.87  ? 61  MET A HE1  61  MET A 1HE  1 
ATOM 947  H HE2  . MET A 1 61  ? 45.643 18.917  16.444 1.00 1.87  ? 61  MET A HE2  61  MET A 2HE  1 
ATOM 948  H HE3  . MET A 1 61  ? 45.215 17.235  16.046 1.00 1.87  ? 61  MET A HE3  61  MET A 3HE  1 
ATOM 949  N N    . PRO A 1 62  ? 42.716 14.162  15.846 1.00 2.14  ? 62  PRO A N    62  PRO A N    1 
ATOM 950  C CA   . PRO A 1 62  ? 42.628 12.720  16.419 1.00 2.14  ? 62  PRO A CA   62  PRO A CA   1 
ATOM 951  C C    . PRO A 1 62  ? 42.584 12.706  17.888 1.00 2.14  ? 62  PRO A C    62  PRO A C    1 
ATOM 952  O O    . PRO A 1 62  ? 42.004 11.814  17.410 1.00 2.14  ? 62  PRO A O    62  PRO A O    1 
ATOM 953  C CB   . PRO A 1 62  ? 43.908 12.029  15.937 1.00 2.14  ? 62  PRO A CB   62  PRO A CB   1 
ATOM 954  C CG   . PRO A 1 62  ? 44.241 12.726  14.662 1.00 2.14  ? 62  PRO A CG   62  PRO A CG   1 
ATOM 955  C CD   . PRO A 1 62  ? 43.929 14.173  14.933 1.00 2.14  ? 62  PRO A CD   62  PRO A CD   1 
ATOM 956  H HA   . PRO A 1 62  ? 41.745 12.217  16.000 1.00 2.14  ? 62  PRO A HA   62  PRO A HA   1 
ATOM 957  H 1HB  . PRO A 1 62  ? 44.698 12.128  16.696 1.00 2.14  ? 62  PRO A 1HB  62  PRO A 1HB  1 
ATOM 958  H 2HB  . PRO A 1 62  ? 43.726 10.953  15.800 1.00 2.14  ? 62  PRO A 2HB  62  PRO A 2HB  1 
ATOM 959  H 1HG  . PRO A 1 62  ? 45.298 12.562  14.404 1.00 2.14  ? 62  PRO A 1HG  62  PRO A 1HG  1 
ATOM 960  H 2HG  . PRO A 1 62  ? 43.645 12.312  13.836 1.00 2.14  ? 62  PRO A 2HG  62  PRO A 2HG  1 
ATOM 961  H 1HD  . PRO A 1 62  ? 44.787 14.647  15.433 1.00 2.14  ? 62  PRO A 1HD  62  PRO A 1HD  1 
ATOM 962  H 2HD  . PRO A 1 62  ? 43.701 14.684  13.986 1.00 2.14  ? 62  PRO A 2HD  62  PRO A 2HD  1 
ATOM 963  N N    . GLY A 1 63  ? 41.879 12.186  18.736 1.00 2.23  ? 63  GLY A N    63  GLY A N    1 
ATOM 964  C CA   . GLY A 1 63  ? 41.463 11.837  20.022 1.00 2.23  ? 63  GLY A CA   63  GLY A CA   1 
ATOM 965  C C    . GLY A 1 63  ? 40.779 12.975  20.677 1.00 2.23  ? 63  GLY A C    63  GLY A C    1 
ATOM 966  O O    . GLY A 1 63  ? 40.222 12.721  21.897 1.00 2.23  ? 63  GLY A O    63  GLY A O    1 
ATOM 967  H H    . GLY A 1 63  ? 41.332 11.530  18.173 1.00 2.23  ? 63  GLY A H    63  GLY A H    1 
ATOM 968  H HA2  . GLY A 1 63  ? 40.791 10.980  19.966 1.00 2.23  ? 63  GLY A HA2  63  GLY A 1HA  1 
ATOM 969  H HA3  . GLY A 1 63  ? 42.325 11.530  20.613 1.00 2.23  ? 63  GLY A HA3  63  GLY A 2HA  1 
ATOM 970  N N    . LYS A 1 64  ? 40.719 14.210  19.783 1.00 2.08  ? 64  LYS A N    64  LYS A N    1 
ATOM 971  C CA   . LYS A 1 64  ? 40.056 15.408  20.553 1.00 2.08  ? 64  LYS A CA   64  LYS A CA   1 
ATOM 972  C C    . LYS A 1 64  ? 38.492 15.259  19.822 1.00 2.08  ? 64  LYS A C    64  LYS A C    1 
ATOM 973  O O    . LYS A 1 64  ? 38.092 14.217  18.845 1.00 2.08  ? 64  LYS A O    64  LYS A O    1 
ATOM 974  C CB   . LYS A 1 64  ? 40.747 16.751  20.315 1.00 2.08  ? 64  LYS A CB   64  LYS A CB   1 
ATOM 975  C CG   . LYS A 1 64  ? 42.219 16.779  20.704 1.00 2.08  ? 64  LYS A CG   64  LYS A CG   1 
ATOM 976  C CD   . LYS A 1 64  ? 42.801 18.178  20.566 1.00 2.08  ? 64  LYS A CD   64  LYS A CD   1 
ATOM 977  C CE   . LYS A 1 64  ? 42.270 19.109  21.646 1.00 2.08  ? 64  LYS A CE   64  LYS A CE   1 
ATOM 978  N NZ   . LYS A 1 64  ? 42.651 20.525  21.397 1.00 2.08  ? 64  LYS A NZ   64  LYS A NZ   1 
ATOM 979  H H    . LYS A 1 64  ? 40.731 14.204  18.830 1.00 2.08  ? 64  LYS A H    64  LYS A H    1 
ATOM 980  H HA   . LYS A 1 64  ? 40.112 15.204  21.623 1.00 2.08  ? 64  LYS A HA   64  LYS A HA   1 
ATOM 981  H HB2  . LYS A 1 64  ? 40.675 17.016  19.260 1.00 2.08  ? 64  LYS A HB2  64  LYS A 1HB  1 
ATOM 982  H HB3  . LYS A 1 64  ? 40.236 17.529  20.884 1.00 2.08  ? 64  LYS A HB3  64  LYS A 2HB  1 
ATOM 983  H HG2  . LYS A 1 64  ? 42.329 16.450  21.738 1.00 2.08  ? 64  LYS A HG2  64  LYS A 1HG  1 
ATOM 984  H HG3  . LYS A 1 64  ? 42.778 16.097  20.063 1.00 2.08  ? 64  LYS A HG3  64  LYS A 2HG  1 
ATOM 985  H HD2  . LYS A 1 64  ? 43.888 18.129  20.642 1.00 2.08  ? 64  LYS A HD2  64  LYS A 1HD  1 
ATOM 986  H HD3  . LYS A 1 64  ? 42.541 18.585  19.589 1.00 2.08  ? 64  LYS A HD3  64  LYS A 2HD  1 
ATOM 987  H HE2  . LYS A 1 64  ? 41.184 19.039  21.684 1.00 2.08  ? 64  LYS A HE2  64  LYS A 1HE  1 
ATOM 988  H HE3  . LYS A 1 64  ? 42.666 18.805  22.615 1.00 2.08  ? 64  LYS A HE3  64  LYS A 2HE  1 
ATOM 989  H HZ1  . LYS A 1 64  ? 42.281 21.109  22.134 1.00 2.08  ? 64  LYS A HZ1  64  LYS A 1HZ  1 
ATOM 990  H HZ2  . LYS A 1 64  ? 43.658 20.605  21.378 1.00 2.08  ? 64  LYS A HZ2  64  LYS A 2HZ  1 
ATOM 991  H HZ3  . LYS A 1 64  ? 42.273 20.825  20.509 1.00 2.08  ? 64  LYS A HZ3  64  LYS A 3HZ  1 
ATOM 992  N N    . GLY A 1 65  ? 37.566 16.245  20.413 1.00 1.93  ? 65  GLY A N    65  GLY A N    1 
ATOM 993  C CA   . GLY A 1 65  ? 36.346 16.076  19.617 1.00 1.93  ? 65  GLY A CA   65  GLY A CA   1 
ATOM 994  C C    . GLY A 1 65  ? 36.641 17.239  18.403 1.00 1.93  ? 65  GLY A C    65  GLY A C    1 
ATOM 995  O O    . GLY A 1 65  ? 37.836 17.276  17.571 1.00 1.93  ? 65  GLY A O    65  GLY A O    1 
ATOM 996  H H    . GLY A 1 65  ? 37.724 16.925  21.166 1.00 1.93  ? 65  GLY A H    65  GLY A H    1 
ATOM 997  H HA2  . GLY A 1 65  ? 36.278 15.045  19.270 1.00 1.93  ? 65  GLY A HA2  65  GLY A 1HA  1 
ATOM 998  H HA3  . GLY A 1 65  ? 35.474 16.263  20.242 1.00 1.93  ? 65  GLY A HA3  65  GLY A 2HA  1 
ATOM 999  N N    . LEU A 1 66  ? 35.318 17.766  18.053 1.00 1.73  ? 66  LEU A N    66  LEU A N    1 
ATOM 1000 C CA   . LEU A 1 66  ? 35.187 18.742  17.072 1.00 1.73  ? 66  LEU A CA   66  LEU A CA   1 
ATOM 1001 C C    . LEU A 1 66  ? 35.368 20.066  17.668 1.00 1.73  ? 66  LEU A C    66  LEU A C    1 
ATOM 1002 O O    . LEU A 1 66  ? 34.579 20.111  18.701 1.00 1.73  ? 66  LEU A O    66  LEU A O    1 
ATOM 1003 C CB   . LEU A 1 66  ? 33.812 18.646  16.399 1.00 1.73  ? 66  LEU A CB   66  LEU A CB   1 
ATOM 1004 C CG   . LEU A 1 66  ? 33.594 17.420  15.503 1.00 1.73  ? 66  LEU A CG   66  LEU A CG   1 
ATOM 1005 C CD1  . LEU A 1 66  ? 32.196 17.471  14.903 1.00 1.73  ? 66  LEU A CD1  66  LEU A CD1  1 
ATOM 1006 C CD2  . LEU A 1 66  ? 34.656 17.392  14.413 1.00 1.73  ? 66  LEU A CD2  66  LEU A CD2  1 
ATOM 1007 H H    . LEU A 1 66  ? 34.532 17.539  18.623 1.00 1.73  ? 66  LEU A H    66  LEU A H    1 
ATOM 1008 H HA   . LEU A 1 66  ? 35.956 18.579  16.317 1.00 1.73  ? 66  LEU A HA   66  LEU A HA   1 
ATOM 1009 H HB2  . LEU A 1 66  ? 33.047 18.630  17.173 1.00 1.73  ? 66  LEU A HB2  66  LEU A 1HB  1 
ATOM 1010 H HB3  . LEU A 1 66  ? 33.661 19.535  15.787 1.00 1.73  ? 66  LEU A HB3  66  LEU A 2HB  1 
ATOM 1011 H HG   . LEU A 1 66  ? 33.666 16.513  16.103 1.00 1.73  ? 66  LEU A HG   66  LEU A HG   1 
ATOM 1012 H HD11 . LEU A 1 66  ? 32.041 16.600  14.266 1.00 1.73  ? 66  LEU A HD11 66  LEU A 1HD1 1 
ATOM 1013 H HD12 . LEU A 1 66  ? 31.456 17.470  15.703 1.00 1.73  ? 66  LEU A HD12 66  LEU A 2HD1 1 
ATOM 1014 H HD13 . LEU A 1 66  ? 32.088 18.378  14.309 1.00 1.73  ? 66  LEU A HD13 66  LEU A 3HD1 1 
ATOM 1015 H HD21 . LEU A 1 66  ? 34.502 16.521  13.777 1.00 1.73  ? 66  LEU A HD21 66  LEU A 1HD2 1 
ATOM 1016 H HD22 . LEU A 1 66  ? 34.584 18.299  13.812 1.00 1.73  ? 66  LEU A HD22 66  LEU A 2HD2 1 
ATOM 1017 H HD23 . LEU A 1 66  ? 35.644 17.338  14.870 1.00 1.73  ? 66  LEU A HD23 66  LEU A 3HD2 1 
ATOM 1018 N N    . GLU A 1 67  ? 36.327 21.035  16.944 1.00 1.63  ? 67  GLU A N    67  GLU A N    1 
ATOM 1019 C CA   . GLU A 1 67  ? 36.643 22.332  17.327 1.00 1.63  ? 67  GLU A CA   67  GLU A CA   1 
ATOM 1020 C C    . GLU A 1 67  ? 36.071 23.307  16.299 1.00 1.63  ? 67  GLU A C    67  GLU A C    1 
ATOM 1021 O O    . GLU A 1 67  ? 36.423 23.125  15.014 1.00 1.63  ? 67  GLU A O    67  GLU A O    1 
ATOM 1022 C CB   . GLU A 1 67  ? 38.160 22.482  17.458 1.00 1.63  ? 67  GLU A CB   67  GLU A CB   1 
ATOM 1023 C CG   . GLU A 1 67  ? 38.793 21.578  18.507 1.00 1.63  ? 67  GLU A CG   67  GLU A CG   1 
ATOM 1024 C CD   . GLU A 1 67  ? 40.291 21.694  18.552 1.00 1.63  ? 67  GLU A CD   67  GLU A CD   1 
ATOM 1025 O OE1  . GLU A 1 67  ? 40.862 22.150  17.591 1.00 1.63  ? 67  GLU A OE1  67  GLU A OE1  1 
ATOM 1026 O OE2  . GLU A 1 67  ? 40.866 21.327  19.550 1.00 1.63  ? 67  GLU A OE2  67  GLU A OE2  1 
ATOM 1027 H H    . GLU A 1 67  ? 36.729 20.753  16.180 1.00 1.63  ? 67  GLU A H    67  GLU A H    1 
ATOM 1028 H HA   . GLU A 1 67  ? 36.184 22.528  18.296 1.00 1.63  ? 67  GLU A HA   67  GLU A HA   1 
ATOM 1029 H HB2  . GLU A 1 67  ? 38.632 22.262  16.500 1.00 1.63  ? 67  GLU A HB2  67  GLU A 1HB  1 
ATOM 1030 H HB3  . GLU A 1 67  ? 38.404 23.513  17.714 1.00 1.63  ? 67  GLU A HB3  67  GLU A 2HB  1 
ATOM 1031 H HG2  . GLU A 1 67  ? 38.390 21.839  19.486 1.00 1.63  ? 67  GLU A HG2  67  GLU A 1HG  1 
ATOM 1032 H HG3  . GLU A 1 67  ? 38.519 20.546  18.295 1.00 1.63  ? 67  GLU A HG3  67  GLU A 2HG  1 
ATOM 1033 N N    . TRP A 1 68  ? 35.099 24.385  16.831 1.00 1.50  ? 68  TRP A N    68  TRP A N    1 
ATOM 1034 C CA   . TRP A 1 68  ? 34.646 25.307  15.838 1.00 1.50  ? 68  TRP A CA   68  TRP A CA   1 
ATOM 1035 C C    . TRP A 1 68  ? 35.671 26.332  15.585 1.00 1.50  ? 68  TRP A C    68  TRP A C    1 
ATOM 1036 O O    . TRP A 1 68  ? 36.016 26.963  16.691 1.00 1.50  ? 68  TRP A O    68  TRP A O    1 
ATOM 1037 C CB   . TRP A 1 68  ? 33.344 25.983  16.272 1.00 1.50  ? 68  TRP A CB   68  TRP A CB   1 
ATOM 1038 C CG   . TRP A 1 68  ? 32.201 25.029  16.438 1.00 1.50  ? 68  TRP A CG   68  TRP A CG   1 
ATOM 1039 C CD1  . TRP A 1 68  ? 31.910 24.290  17.546 1.00 1.50  ? 68  TRP A CD1  68  TRP A CD1  1 
ATOM 1040 C CD2  . TRP A 1 68  ? 31.183 24.704  15.461 1.00 1.50  ? 68  TRP A CD2  68  TRP A CD2  1 
ATOM 1041 N NE1  . TRP A 1 68  ? 30.788 23.531  17.326 1.00 1.50  ? 68  TRP A NE1  68  TRP A NE1  1 
ATOM 1042 C CE2  . TRP A 1 68  ? 30.329 23.772  16.056 1.00 1.50  ? 68  TRP A CE2  68  TRP A CE2  1 
ATOM 1043 C CE3  . TRP A 1 68  ? 30.932 25.124  14.148 1.00 1.50  ? 68  TRP A CE3  68  TRP A CE3  1 
ATOM 1044 C CZ2  . TRP A 1 68  ? 29.236 23.245  15.385 1.00 1.50  ? 68  TRP A CZ2  68  TRP A CZ2  1 
ATOM 1045 C CZ3  . TRP A 1 68  ? 29.836 24.596  13.476 1.00 1.50  ? 68  TRP A CZ3  68  TRP A CZ3  1 
ATOM 1046 C CH2  . TRP A 1 68  ? 29.010 23.682  14.080 1.00 1.50  ? 68  TRP A CH2  68  TRP A CH2  1 
ATOM 1047 H H    . TRP A 1 68  ? 34.899 24.530  17.822 1.00 1.50  ? 68  TRP A H    68  TRP A H    1 
ATOM 1048 H HA   . TRP A 1 68  ? 34.458 24.758  14.916 1.00 1.50  ? 68  TRP A HA   68  TRP A HA   1 
ATOM 1049 H HB2  . TRP A 1 68  ? 33.501 26.499  17.220 1.00 1.50  ? 68  TRP A HB2  68  TRP A 1HB  1 
ATOM 1050 H HB3  . TRP A 1 68  ? 33.060 26.733  15.534 1.00 1.50  ? 68  TRP A HB3  68  TRP A 2HB  1 
ATOM 1051 H HD1  . TRP A 1 68  ? 32.484 24.301  18.470 1.00 1.50  ? 68  TRP A HD1  68  TRP A HD1  1 
ATOM 1052 H HE1  . TRP A 1 68  ? 30.367 22.896  17.990 1.00 1.50  ? 68  TRP A HE1  68  TRP A HE1  1 
ATOM 1053 H HE3  . TRP A 1 68  ? 31.583 25.851  13.665 1.00 1.50  ? 68  TRP A HE3  68  TRP A HE3  1 
ATOM 1054 H HZ2  . TRP A 1 68  ? 28.568 22.518  15.848 1.00 1.50  ? 68  TRP A HZ2  68  TRP A HZ2  1 
ATOM 1055 H HZ3  . TRP A 1 68  ? 29.648 24.928  12.455 1.00 1.50  ? 68  TRP A HZ3  68  TRP A HZ3  1 
ATOM 1056 H HH2  . TRP A 1 68  ? 28.158 23.289  13.524 1.00 1.50  ? 68  TRP A HH2  68  TRP A HH2  1 
ATOM 1057 N N    . MET A 1 69  ? 36.145 26.513  14.135 1.00 1.36  ? 69  MET A N    69  MET A N    1 
ATOM 1058 C CA   . MET A 1 69  ? 37.121 27.398  13.723 1.00 1.36  ? 69  MET A CA   69  MET A CA   1 
ATOM 1059 C C    . MET A 1 69  ? 36.547 28.775  13.328 1.00 1.36  ? 69  MET A C    69  MET A C    1 
ATOM 1060 O O    . MET A 1 69  ? 36.876 29.761  13.842 1.00 1.36  ? 69  MET A O    69  MET A O    1 
ATOM 1061 C CB   . MET A 1 69  ? 37.889 26.757  12.569 1.00 1.36  ? 69  MET A CB   69  MET A CB   1 
ATOM 1062 C CG   . MET A 1 69  ? 38.472 25.386  12.884 1.00 1.36  ? 69  MET A CG   69  MET A CG   1 
ATOM 1063 S SD   . MET A 1 69  ? 39.562 24.778  11.582 1.00 1.36  ? 69  MET A SD   69  MET A SD   1 
ATOM 1064 C CE   . MET A 1 69  ? 38.376 24.418  10.290 1.00 1.36  ? 69  MET A CE   69  MET A CE   1 
ATOM 1065 H H    . MET A 1 69  ? 35.678 26.073  13.485 1.00 1.36  ? 69  MET A H    69  MET A H    1 
ATOM 1066 H HA   . MET A 1 69  ? 37.797 27.581  14.558 1.00 1.36  ? 69  MET A HA   69  MET A HA   1 
ATOM 1067 H HB2  . MET A 1 69  ? 37.229 26.649  11.709 1.00 1.36  ? 69  MET A HB2  69  MET A 1HB  1 
ATOM 1068 H HB3  . MET A 1 69  ? 38.711 27.409  12.271 1.00 1.36  ? 69  MET A HB3  69  MET A 2HB  1 
ATOM 1069 H HG2  . MET A 1 69  ? 39.039 25.438  13.813 1.00 1.36  ? 69  MET A HG2  69  MET A 1HG  1 
ATOM 1070 H HG3  . MET A 1 69  ? 37.662 24.669  13.019 1.00 1.36  ? 69  MET A HG3  69  MET A 2HG  1 
ATOM 1071 H HE1  . MET A 1 69  ? 38.899 24.031  9.414  1.00 1.36  ? 69  MET A HE1  69  MET A 1HE  1 
ATOM 1072 H HE2  . MET A 1 69  ? 37.664 23.673  10.646 1.00 1.36  ? 69  MET A HE2  69  MET A 2HE  1 
ATOM 1073 H HE3  . MET A 1 69  ? 37.843 25.330  10.020 1.00 1.36  ? 69  MET A HE3  69  MET A 3HE  1 
ATOM 1074 N N    . GLY A 1 70  ? 35.350 28.878  12.764 1.00 1.25  ? 70  GLY A N    70  GLY A N    1 
ATOM 1075 C CA   . GLY A 1 70  ? 34.847 30.204  12.291 1.00 1.25  ? 70  GLY A CA   70  GLY A CA   1 
ATOM 1076 C C    . GLY A 1 70  ? 33.427 29.900  11.771 1.00 1.25  ? 70  GLY A C    70  GLY A C    1 
ATOM 1077 O O    . GLY A 1 70  ? 33.303 28.712  11.208 1.00 1.25  ? 70  GLY A O    70  GLY A O    1 
ATOM 1078 H H    . GLY A 1 70  ? 34.989 27.928  12.388 1.00 1.25  ? 70  GLY A H    70  GLY A H    1 
ATOM 1079 H HA2  . GLY A 1 70  ? 34.860 30.914  13.118 1.00 1.25  ? 70  GLY A HA2  70  GLY A 1HA  1 
ATOM 1080 H HA3  . GLY A 1 70  ? 35.514 30.593  11.523 1.00 1.25  ? 70  GLY A HA3  70  GLY A 2HA  1 
ATOM 1081 N N    . ILE A 1 71  ? 32.449 30.981  11.963 1.00 1.30  ? 71  ILE A N    71  ILE A N    1 
ATOM 1082 C CA   . ILE A 1 71  ? 31.132 30.942  11.601 1.00 1.30  ? 71  ILE A CA   71  ILE A CA   1 
ATOM 1083 C C    . ILE A 1 71  ? 30.799 32.146  10.773 1.00 1.30  ? 71  ILE A C    71  ILE A C    1 
ATOM 1084 O O    . ILE A 1 71  ? 31.371 33.182  11.274 1.00 1.30  ? 71  ILE A O    71  ILE A O    1 
ATOM 1085 C CB   . ILE A 1 71  ? 30.237 30.870  12.851 1.00 1.30  ? 71  ILE A CB   71  ILE A CB   1 
ATOM 1086 C CG1  . ILE A 1 71  ? 30.527 29.592  13.642 1.00 1.30  ? 71  ILE A CG1  71  ILE A CG1  1 
ATOM 1087 C CG2  . ILE A 1 71  ? 28.769 30.935  12.459 1.00 1.30  ? 71  ILE A CG2  71  ILE A CG2  1 
ATOM 1088 C CD1  . ILE A 1 71  ? 29.837 29.535  14.986 1.00 1.30  ? 71  ILE A CD1  71  ILE A CD1  1 
ATOM 1089 H H    . ILE A 1 71  ? 32.744 31.692  12.491 1.00 1.30  ? 71  ILE A H    71  ILE A H    1 
ATOM 1090 H HA   . ILE A 1 71  ? 30.966 30.050  10.999 1.00 1.30  ? 71  ILE A HA   71  ILE A HA   1 
ATOM 1091 H HB   . ILE A 1 71  ? 30.464 31.707  13.510 1.00 1.30  ? 71  ILE A HB   71  ILE A HB   1 
ATOM 1092 H HG12 . ILE A 1 71  ? 30.213 28.725  13.061 1.00 1.30  ? 71  ILE A HG12 71  ILE A 1HG1 1 
ATOM 1093 H HG13 . ILE A 1 71  ? 31.601 29.502  13.807 1.00 1.30  ? 71  ILE A HG13 71  ILE A 2HG1 1 
ATOM 1094 H HG21 . ILE A 1 71  ? 28.150 30.882  13.354 1.00 1.30  ? 71  ILE A HG21 71  ILE A 1HG2 1 
ATOM 1095 H HG22 . ILE A 1 71  ? 28.573 31.871  11.938 1.00 1.30  ? 71  ILE A HG22 71  ILE A 2HG2 1 
ATOM 1096 H HG23 . ILE A 1 71  ? 28.530 30.098  11.802 1.00 1.30  ? 71  ILE A HG23 71  ILE A 3HG2 1 
ATOM 1097 H HD11 . ILE A 1 71  ? 30.091 28.601  15.487 1.00 1.30  ? 71  ILE A HD11 71  ILE A 1HD1 1 
ATOM 1098 H HD12 . ILE A 1 71  ? 30.164 30.376  15.599 1.00 1.30  ? 71  ILE A HD12 71  ILE A 2HD1 1 
ATOM 1099 H HD13 . ILE A 1 71  ? 28.758 29.588  14.843 1.00 1.30  ? 71  ILE A HD13 71  ILE A 3HD1 1 
ATOM 1100 N N    . ILE A 1 72  ? 29.958 31.997  9.472  1.00 1.34  ? 72  ILE A N    72  ILE A N    1 
ATOM 1101 C CA   . ILE A 1 72  ? 29.475 33.027  8.779  1.00 1.34  ? 72  ILE A CA   72  ILE A CA   1 
ATOM 1102 C C    . ILE A 1 72  ? 28.052 33.096  8.911  1.00 1.34  ? 72  ILE A C    72  ILE A C    1 
ATOM 1103 O O    . ILE A 1 72  ? 27.527 31.894  8.844  1.00 1.34  ? 72  ILE A O    72  ILE A O    1 
ATOM 1104 C CB   . ILE A 1 72  ? 29.869 32.910  7.295  1.00 1.34  ? 72  ILE A CB   72  ILE A CB   1 
ATOM 1105 C CG1  . ILE A 1 72  ? 31.383 33.060  7.131  1.00 1.34  ? 72  ILE A CG1  72  ILE A CG1  1 
ATOM 1106 C CG2  . ILE A 1 72  ? 29.134 33.953  6.466  1.00 1.34  ? 72  ILE A CG2  72  ILE A CG2  1 
ATOM 1107 C CD1  . ILE A 1 72  ? 31.901 34.438  7.475  1.00 1.34  ? 72  ILE A CD1  72  ILE A CD1  1 
ATOM 1108 H H    . ILE A 1 72  ? 29.762 31.167  9.194  1.00 1.34  ? 72  ILE A H    72  ILE A H    1 
ATOM 1109 H HA   . ILE A 1 72  ? 29.902 33.945  9.180  1.00 1.34  ? 72  ILE A HA   72  ILE A HA   1 
ATOM 1110 H HB   . ILE A 1 72  ? 29.609 31.918  6.927  1.00 1.34  ? 72  ILE A HB   72  ILE A HB   1 
ATOM 1111 H HG12 . ILE A 1 72  ? 31.891 32.336  7.766  1.00 1.34  ? 72  ILE A HG12 72  ILE A 1HG1 1 
ATOM 1112 H HG13 . ILE A 1 72  ? 31.661 32.840  6.099  1.00 1.34  ? 72  ILE A HG13 72  ILE A 2HG1 1 
ATOM 1113 H HG21 . ILE A 1 72  ? 29.425 33.856  5.420  1.00 1.34  ? 72  ILE A HG21 72  ILE A 1HG2 1 
ATOM 1114 H HG22 . ILE A 1 72  ? 28.060 33.801  6.559  1.00 1.34  ? 72  ILE A HG22 72  ILE A 2HG2 1 
ATOM 1115 H HG23 . ILE A 1 72  ? 29.392 34.950  6.823  1.00 1.34  ? 72  ILE A HG23 72  ILE A 3HG2 1 
ATOM 1116 H HD11 . ILE A 1 72  ? 32.982 34.466  7.333  1.00 1.34  ? 72  ILE A HD11 72  ILE A 1HD1 1 
ATOM 1117 H HD12 . ILE A 1 72  ? 31.431 35.177  6.825  1.00 1.34  ? 72  ILE A HD12 72  ILE A 2HD1 1 
ATOM 1118 H HD13 . ILE A 1 72  ? 31.666 34.666  8.513  1.00 1.34  ? 72  ILE A HD13 72  ILE A 3HD1 1 
ATOM 1119 N N    . TYR A 1 73  ? 27.468 34.511  9.184  1.00 1.65  ? 73  TYR A N    73  TYR A N    1 
ATOM 1120 C CA   . TYR A 1 73  ? 25.952 34.603  8.921  1.00 1.65  ? 73  TYR A CA   73  TYR A CA   1 
ATOM 1121 C C    . TYR A 1 73  ? 25.662 35.570  7.803  1.00 1.65  ? 73  TYR A C    73  TYR A C    1 
ATOM 1122 O O    . TYR A 1 73  ? 25.882 36.803  8.208  1.00 1.65  ? 73  TYR A O    73  TYR A O    1 
ATOM 1123 C CB   . TYR A 1 73  ? 25.177 35.038  10.167 1.00 1.65  ? 73  TYR A CB   73  TYR A CB   1 
ATOM 1124 C CG   . TYR A 1 73  ? 23.679 35.093  9.966  1.00 1.65  ? 73  TYR A CG   73  TYR A CG   1 
ATOM 1125 C CD1  . TYR A 1 73  ? 23.043 34.112  9.219  1.00 1.65  ? 73  TYR A CD1  73  TYR A CD1  1 
ATOM 1126 C CD2  . TYR A 1 73  ? 22.941 36.123  10.529 1.00 1.65  ? 73  TYR A CD2  73  TYR A CD2  1 
ATOM 1127 C CE1  . TYR A 1 73  ? 21.675 34.162  9.035  1.00 1.65  ? 73  TYR A CE1  73  TYR A CE1  1 
ATOM 1128 C CE2  . TYR A 1 73  ? 21.572 36.173  10.345 1.00 1.65  ? 73  TYR A CE2  73  TYR A CE2  1 
ATOM 1129 C CZ   . TYR A 1 73  ? 20.940 35.198  9.602  1.00 1.65  ? 73  TYR A CZ   73  TYR A CZ   1 
ATOM 1130 O OH   . TYR A 1 73  ? 19.577 35.247  9.419  1.00 1.65  ? 73  TYR A OH   73  TYR A OH   1 
ATOM 1131 H H    . TYR A 1 73  ? 28.060 35.262  9.401  1.00 1.65  ? 73  TYR A H    73  TYR A H    1 
ATOM 1132 H HA   . TYR A 1 73  ? 25.591 33.615  8.632  1.00 1.65  ? 73  TYR A HA   73  TYR A HA   1 
ATOM 1133 H HB2  . TYR A 1 73  ? 25.386 34.348  10.986 1.00 1.65  ? 73  TYR A HB2  73  TYR A 1HB  1 
ATOM 1134 H HB3  . TYR A 1 73  ? 25.515 36.027  10.478 1.00 1.65  ? 73  TYR A HB3  73  TYR A 2HB  1 
ATOM 1135 H HD1  . TYR A 1 73  ? 23.623 33.302  8.776  1.00 1.65  ? 73  TYR A HD1  73  TYR A HD1  1 
ATOM 1136 H HD2  . TYR A 1 73  ? 23.440 36.895  11.115 1.00 1.65  ? 73  TYR A HD2  73  TYR A HD2  1 
ATOM 1137 H HE1  . TYR A 1 73  ? 21.175 33.392  8.448  1.00 1.65  ? 73  TYR A HE1  73  TYR A HE1  1 
ATOM 1138 H HE2  . TYR A 1 73  ? 20.992 36.984  10.787 1.00 1.65  ? 73  TYR A HE2  73  TYR A HE2  1 
ATOM 1139 H HH   . TYR A 1 73  ? 19.225 36.025  9.858  1.00 1.65  ? 73  TYR A HH   73  TYR A HH   1 
ATOM 1140 N N    . PRO A 1 74  ? 25.142 34.952  6.475  1.00 1.83  ? 74  PRO A N    74  PRO A N    1 
ATOM 1141 C CA   . PRO A 1 74  ? 24.811 35.711  5.394  1.00 1.83  ? 74  PRO A CA   74  PRO A CA   1 
ATOM 1142 C C    . PRO A 1 74  ? 23.710 36.613  6.049  1.00 1.83  ? 74  PRO A C    74  PRO A C    1 
ATOM 1143 O O    . PRO A 1 74  ? 22.712 36.114  6.926  1.00 1.83  ? 74  PRO A O    74  PRO A O    1 
ATOM 1144 C CB   . PRO A 1 74  ? 24.296 34.705  4.361  1.00 1.83  ? 74  PRO A CB   74  PRO A CB   1 
ATOM 1145 C CG   . PRO A 1 74  ? 24.956 33.423  4.738  1.00 1.83  ? 74  PRO A CG   74  PRO A CG   1 
ATOM 1146 C CD   . PRO A 1 74  ? 25.065 33.485  6.238  1.00 1.83  ? 74  PRO A CD   74  PRO A CD   1 
ATOM 1147 H HA   . PRO A 1 74  ? 25.713 36.217  5.017  1.00 1.83  ? 74  PRO A HA   74  PRO A HA   1 
ATOM 1148 H HB2  . PRO A 1 74  ? 23.198 34.649  4.405  1.00 1.83  ? 74  PRO A HB2  74  PRO A 1HB  1 
ATOM 1149 H HB3  . PRO A 1 74  ? 24.560 35.038  3.346  1.00 1.83  ? 74  PRO A HB3  74  PRO A 2HB  1 
ATOM 1150 H HG2  . PRO A 1 74  ? 24.354 32.569  4.393  1.00 1.83  ? 74  PRO A HG2  74  PRO A 1HG  1 
ATOM 1151 H HG3  . PRO A 1 74  ? 25.936 33.340  4.245  1.00 1.83  ? 74  PRO A HG3  74  PRO A 2HG  1 
ATOM 1152 H HD2  . PRO A 1 74  ? 24.164 33.046  6.691  1.00 1.83  ? 74  PRO A HD2  74  PRO A 1HD  1 
ATOM 1153 H HD3  . PRO A 1 74  ? 25.966 32.945  6.564  1.00 1.83  ? 74  PRO A HD3  74  PRO A 2HD  1 
ATOM 1154 N N    . GLY A 1 75  ? 23.983 37.937  5.496  1.00 1.98  ? 75  GLY A N    75  GLY A N    1 
ATOM 1155 C CA   . GLY A 1 75  ? 23.108 39.144  5.786  1.00 1.98  ? 75  GLY A CA   75  GLY A CA   1 
ATOM 1156 C C    . GLY A 1 75  ? 23.688 39.814  6.944  1.00 1.98  ? 75  GLY A C    75  GLY A C    1 
ATOM 1157 O O    . GLY A 1 75  ? 23.680 41.088  6.626  1.00 1.98  ? 75  GLY A O    75  GLY A O    1 
ATOM 1158 H H    . GLY A 1 75  ? 24.767 38.111  4.888  1.00 1.98  ? 75  GLY A H    75  GLY A H    1 
ATOM 1159 H HA2  . GLY A 1 75  ? 23.080 39.793  4.911  1.00 1.98  ? 75  GLY A HA2  75  GLY A 1HA  1 
ATOM 1160 H HA3  . GLY A 1 75  ? 22.087 38.816  5.975  1.00 1.98  ? 75  GLY A HA3  75  GLY A 2HA  1 
ATOM 1161 N N    . ASP A 1 76  ? 24.367 39.032  8.135  1.00 2.49  ? 76  ASP A N    76  ASP A N    1 
ATOM 1162 C CA   . ASP A 1 76  ? 24.969 39.884  9.114  1.00 2.49  ? 76  ASP A CA   76  ASP A CA   1 
ATOM 1163 C C    . ASP A 1 76  ? 26.153 39.458  8.847  1.00 2.49  ? 76  ASP A C    76  ASP A C    1 
ATOM 1164 O O    . ASP A 1 76  ? 26.184 38.690  9.989  1.00 2.49  ? 76  ASP A O    76  ASP A O    1 
ATOM 1165 C CB   . ASP A 1 76  ? 24.595 39.651  10.580 1.00 2.49  ? 76  ASP A CB   76  ASP A CB   1 
ATOM 1166 C CG   . ASP A 1 76  ? 25.348 40.566  11.537 1.00 2.49  ? 76  ASP A CG   76  ASP A CG   1 
ATOM 1167 O OD1  . ASP A 1 76  ? 26.432 40.981  11.201 1.00 2.49  ? 76  ASP A OD1  76  ASP A OD1  1 
ATOM 1168 O OD2  . ASP A 1 76  ? 24.831 40.842  12.593 1.00 2.49  ? 76  ASP A OD2  76  ASP A OD2  1 
ATOM 1169 H H    . ASP A 1 76  ? 24.759 38.168  8.044  1.00 2.49  ? 76  ASP A H    76  ASP A H    1 
ATOM 1170 H HA   . ASP A 1 76  ? 24.674 40.913  8.906  1.00 2.49  ? 76  ASP A HA   76  ASP A HA   1 
ATOM 1171 H HB2  . ASP A 1 76  ? 23.525 39.812  10.713 1.00 2.49  ? 76  ASP A HB2  76  ASP A 1HB  1 
ATOM 1172 H HB3  . ASP A 1 76  ? 24.806 38.616  10.850 1.00 2.49  ? 76  ASP A HB3  76  ASP A 2HB  1 
ATOM 1173 N N    . SER A 1 77  ? 27.177 40.084  7.939  1.00 2.30  ? 77  SER A N    77  SER A N    1 
ATOM 1174 C CA   . SER A 1 77  ? 28.431 39.866  7.326  1.00 2.30  ? 77  SER A CA   77  SER A CA   1 
ATOM 1175 C C    . SER A 1 77  ? 29.355 39.542  8.477  1.00 2.30  ? 77  SER A C    77  SER A C    1 
ATOM 1176 O O    . SER A 1 77  ? 30.555 39.262  8.018  1.00 2.30  ? 77  SER A O    77  SER A O    1 
ATOM 1177 C CB   . SER A 1 77  ? 28.893 41.085  6.551  1.00 2.30  ? 77  SER A CB   77  SER A CB   1 
ATOM 1178 O OG   . SER A 1 77  ? 29.153 42.159  7.413  1.00 2.30  ? 77  SER A OG   77  SER A OG   1 
ATOM 1179 H H    . SER A 1 77  ? 27.675 39.420  8.531  1.00 2.30  ? 77  SER A H    77  SER A H    1 
ATOM 1180 H HA   . SER A 1 77  ? 28.333 39.036  6.624  1.00 2.30  ? 77  SER A HA   77  SER A HA   1 
ATOM 1181 H HB2  . SER A 1 77  ? 29.794 40.839  5.990  1.00 2.30  ? 77  SER A HB2  77  SER A 1HB  1 
ATOM 1182 H HB3  . SER A 1 77  ? 28.127 41.371  5.832  1.00 2.30  ? 77  SER A HB3  77  SER A 2HB  1 
ATOM 1183 H HG   . SER A 1 77  ? 29.271 41.775  8.286  1.00 2.30  ? 77  SER A HG   77  SER A HG   1 
ATOM 1184 N N    . GLU A 1 78  ? 28.824 39.759  9.969  1.00 1.70  ? 78  GLU A N    78  GLU A N    1 
ATOM 1185 C CA   . GLU A 1 78  ? 29.725 39.405  10.952 1.00 1.70  ? 78  GLU A CA   78  GLU A CA   1 
ATOM 1186 C C    . GLU A 1 78  ? 30.044 37.704  10.523 1.00 1.70  ? 78  GLU A C    78  GLU A C    1 
ATOM 1187 O O    . GLU A 1 78  ? 29.139 36.525  10.203 1.00 1.70  ? 78  GLU A O    78  GLU A O    1 
ATOM 1188 C CB   . GLU A 1 78  ? 29.096 39.643  12.327 1.00 1.70  ? 78  GLU A CB   78  GLU A CB   1 
ATOM 1189 C CG   . GLU A 1 78  ? 30.020 39.346  13.500 1.00 1.70  ? 78  GLU A CG   78  GLU A CG   1 
ATOM 1190 C CD   . GLU A 1 78  ? 29.359 39.559  14.833 1.00 1.70  ? 78  GLU A CD   78  GLU A CD   1 
ATOM 1191 O OE1  . GLU A 1 78  ? 28.578 38.727  15.227 1.00 1.70  ? 78  GLU A OE1  78  GLU A OE1  1 
ATOM 1192 O OE2  . GLU A 1 78  ? 29.636 40.555  15.459 1.00 1.70  ? 78  GLU A OE2  78  GLU A OE2  1 
ATOM 1193 H H    . GLU A 1 78  ? 27.875 40.081  10.173 1.00 1.70  ? 78  GLU A H    78  GLU A H    1 
ATOM 1194 H HA   . GLU A 1 78  ? 30.611 40.032  10.850 1.00 1.70  ? 78  GLU A HA   78  GLU A HA   1 
ATOM 1195 H HB2  . GLU A 1 78  ? 28.778 40.682  12.407 1.00 1.70  ? 78  GLU A HB2  78  GLU A 1HB  1 
ATOM 1196 H HB3  . GLU A 1 78  ? 28.209 39.019  12.434 1.00 1.70  ? 78  GLU A HB3  78  GLU A 2HB  1 
ATOM 1197 H HG2  . GLU A 1 78  ? 30.353 38.311  13.434 1.00 1.70  ? 78  GLU A HG2  78  GLU A 1HG  1 
ATOM 1198 H HG3  . GLU A 1 78  ? 30.898 39.987  13.428 1.00 1.70  ? 78  GLU A HG3  78  GLU A 2HG  1 
ATOM 1199 N N    . THR A 1 79  ? 31.465 37.738  10.731 1.00 1.34  ? 79  THR A N    79  THR A N    1 
ATOM 1200 C CA   . THR A 1 79  ? 32.283 36.535  10.660 1.00 1.34  ? 79  THR A CA   79  THR A CA   1 
ATOM 1201 C C    . THR A 1 79  ? 32.975 36.466  11.958 1.00 1.34  ? 79  THR A C    79  THR A C    1 
ATOM 1202 O O    . THR A 1 79  ? 33.568 37.597  12.202 1.00 1.34  ? 79  THR A O    79  THR A O    1 
ATOM 1203 C CB   . THR A 1 79  ? 33.303 36.553  9.506  1.00 1.34  ? 79  THR A CB   79  THR A CB   1 
ATOM 1204 O OG1  . THR A 1 79  ? 34.110 35.370  9.560  1.00 1.34  ? 79  THR A OG1  79  THR A OG1  1 
ATOM 1205 C CG2  . THR A 1 79  ? 34.198 37.779  9.606  1.00 1.34  ? 79  THR A CG2  79  THR A CG2  1 
ATOM 1206 H H    . THR A 1 79  ? 31.949 38.629  10.894 1.00 1.34  ? 79  THR A H    79  THR A H    1 
ATOM 1207 H HA   . THR A 1 79  ? 31.628 35.679  10.497 1.00 1.34  ? 79  THR A HA   79  THR A HA   1 
ATOM 1208 H HB   . THR A 1 79  ? 32.773 36.573  8.554  1.00 1.34  ? 79  THR A HB   79  THR A HB   1 
ATOM 1209 H HG1  . THR A 1 79  ? 34.029 34.967  10.427 1.00 1.34  ? 79  THR A HG1  79  THR A HG1  1 
ATOM 1210 H HG21 . THR A 1 79  ? 34.912 37.775  8.782  1.00 1.34  ? 79  THR A HG21 79  THR A 1HG2 1 
ATOM 1211 H HG22 . THR A 1 79  ? 33.588 38.680  9.554  1.00 1.34  ? 79  THR A HG22 79  THR A 2HG2 1 
ATOM 1212 H HG23 . THR A 1 79  ? 34.737 37.760  10.552 1.00 1.34  ? 79  THR A HG23 79  THR A 3HG2 1 
ATOM 1213 N N    . ARG A 1 80  ? 32.721 35.182  12.789 1.00 1.42  ? 80  ARG A N    80  ARG A N    1 
ATOM 1214 C CA   . ARG A 1 80  ? 33.268 35.012  14.076 1.00 1.42  ? 80  ARG A CA   80  ARG A CA   1 
ATOM 1215 C C    . ARG A 1 80  ? 34.229 33.914  13.978 1.00 1.42  ? 80  ARG A C    80  ARG A C    1 
ATOM 1216 O O    . ARG A 1 80  ? 33.697 32.808  13.507 1.00 1.42  ? 80  ARG A O    80  ARG A O    1 
ATOM 1217 C CB   . ARG A 1 80  ? 32.201 34.692  15.112 1.00 1.42  ? 80  ARG A CB   80  ARG A CB   1 
ATOM 1218 C CG   . ARG A 1 80  ? 31.174 35.792  15.334 1.00 1.42  ? 80  ARG A CG   80  ARG A CG   1 
ATOM 1219 C CD   . ARG A 1 80  ? 30.222 35.443  16.419 1.00 1.42  ? 80  ARG A CD   80  ARG A CD   1 
ATOM 1220 N NE   . ARG A 1 80  ? 29.223 36.481  16.618 1.00 1.42  ? 80  ARG A NE   80  ARG A NE   1 
ATOM 1221 C CZ   . ARG A 1 80  ? 28.325 36.496  17.622 1.00 1.42  ? 80  ARG A CZ   80  ARG A CZ   1 
ATOM 1222 N NH1  . ARG A 1 80  ? 28.314 35.526  18.509 1.00 1.42  ? 80  ARG A NH1  80  ARG A NH1  1 
ATOM 1223 N NH2  . ARG A 1 80  ? 27.456 37.487  17.717 1.00 1.42  ? 80  ARG A NH2  80  ARG A NH2  1 
ATOM 1224 H H    . ARG A 1 80  ? 32.348 34.466  12.371 1.00 1.42  ? 80  ARG A H    80  ARG A H    1 
ATOM 1225 H HA   . ARG A 1 80  ? 33.753 35.943  14.372 1.00 1.42  ? 80  ARG A HA   80  ARG A HA   1 
ATOM 1226 H HB2  . ARG A 1 80  ? 31.663 33.794  14.814 1.00 1.42  ? 80  ARG A HB2  80  ARG A 1HB  1 
ATOM 1227 H HB3  . ARG A 1 80  ? 32.675 34.486  16.072 1.00 1.42  ? 80  ARG A HB3  80  ARG A 2HB  1 
ATOM 1228 H HG2  . ARG A 1 80  ? 31.684 36.715  15.608 1.00 1.42  ? 80  ARG A HG2  80  ARG A 1HG  1 
ATOM 1229 H HG3  . ARG A 1 80  ? 30.606 35.949  14.416 1.00 1.42  ? 80  ARG A HG3  80  ARG A 2HG  1 
ATOM 1230 H HD2  . ARG A 1 80  ? 29.705 34.517  16.166 1.00 1.42  ? 80  ARG A HD2  80  ARG A 1HD  1 
ATOM 1231 H HD3  . ARG A 1 80  ? 30.767 35.311  17.352 1.00 1.42  ? 80  ARG A HD3  80  ARG A 2HD  1 
ATOM 1232 H HE   . ARG A 1 80  ? 29.201 37.245  15.955 1.00 1.42  ? 80  ARG A HE   80  ARG A HE   1 
ATOM 1233 H HH11 . ARG A 1 80  ? 28.979 34.768  18.437 1.00 1.42  ? 80  ARG A HH11 80  ARG A 1HH1 1 
ATOM 1234 H HH12 . ARG A 1 80  ? 27.642 35.537  19.262 1.00 1.42  ? 80  ARG A HH12 80  ARG A 2HH1 1 
ATOM 1235 H HH21 . ARG A 1 80  ? 27.465 38.234  17.035 1.00 1.42  ? 80  ARG A HH21 80  ARG A 1HH2 1 
ATOM 1236 H HH22 . ARG A 1 80  ? 26.784 37.499  18.469 1.00 1.42  ? 80  ARG A HH22 80  ARG A 2HH2 1 
ATOM 1237 N N    . TYR A 1 81  ? 35.633 34.253  14.499 1.00 1.33  ? 81  TYR A N    81  TYR A N    1 
ATOM 1238 C CA   . TYR A 1 81  ? 36.681 33.231  14.480 1.00 1.33  ? 81  TYR A CA   81  TYR A CA   1 
ATOM 1239 C C    . TYR A 1 81  ? 37.049 32.856  15.956 1.00 1.33  ? 81  TYR A C    81  TYR A C    1 
ATOM 1240 O O    . TYR A 1 81  ? 36.950 33.866  16.872 1.00 1.33  ? 81  TYR A O    81  TYR A O    1 
ATOM 1241 C CB   . TYR A 1 81  ? 37.906 33.729  13.709 1.00 1.33  ? 81  TYR A CB   81  TYR A CB   1 
ATOM 1242 C CG   . TYR A 1 81  ? 37.605 34.144  12.286 1.00 1.33  ? 81  TYR A CG   81  TYR A CG   1 
ATOM 1243 C CD1  . TYR A 1 81  ? 37.167 35.432  12.017 1.00 1.33  ? 81  TYR A CD1  81  TYR A CD1  1 
ATOM 1244 C CD2  . TYR A 1 81  ? 37.766 33.236  11.250 1.00 1.33  ? 81  TYR A CD2  81  TYR A CD2  1 
ATOM 1245 C CE1  . TYR A 1 81  ? 36.892 35.811  10.717 1.00 1.33  ? 81  TYR A CE1  81  TYR A CE1  1 
ATOM 1246 C CE2  . TYR A 1 81  ? 37.491 33.614  9.951  1.00 1.33  ? 81  TYR A CE2  81  TYR A CE2  1 
ATOM 1247 C CZ   . TYR A 1 81  ? 37.055 34.896  9.683  1.00 1.33  ? 81  TYR A CZ   81  TYR A CZ   1 
ATOM 1248 O OH   . TYR A 1 81  ? 36.781 35.273  8.388  1.00 1.33  ? 81  TYR A OH   81  TYR A OH   1 
ATOM 1249 H H    . TYR A 1 81  ? 35.820 35.185  14.877 1.00 1.33  ? 81  TYR A H    81  TYR A H    1 
ATOM 1250 H HA   . TYR A 1 81  ? 36.292 32.345  13.978 1.00 1.33  ? 81  TYR A HA   81  TYR A HA   1 
ATOM 1251 H HB2  . TYR A 1 81  ? 38.340 34.585  14.228 1.00 1.33  ? 81  TYR A HB2  81  TYR A 1HB  1 
ATOM 1252 H HB3  . TYR A 1 81  ? 38.662 32.945  13.682 1.00 1.33  ? 81  TYR A HB3  81  TYR A 2HB  1 
ATOM 1253 H HD1  . TYR A 1 81  ? 37.040 36.146  12.831 1.00 1.33  ? 81  TYR A HD1  81  TYR A HD1  1 
ATOM 1254 H HD2  . TYR A 1 81  ? 38.109 32.223  11.462 1.00 1.33  ? 81  TYR A HD2  81  TYR A HD2  1 
ATOM 1255 H HE1  . TYR A 1 81  ? 36.548 36.823  10.505 1.00 1.33  ? 81  TYR A HE1  81  TYR A HE1  1 
ATOM 1256 H HE2  . TYR A 1 81  ? 37.617 32.900  9.137  1.00 1.33  ? 81  TYR A HE2  81  TYR A HE2  1 
ATOM 1257 H HH   . TYR A 1 81  ? 36.094 35.944  8.390  1.00 1.33  ? 81  TYR A HH   81  TYR A HH   1 
ATOM 1258 N N    . SER A 1 82  ? 37.398 31.357  16.076 1.00 1.42  ? 82  SER A N    82  SER A N    1 
ATOM 1259 C CA   . SER A 1 82  ? 38.006 30.912  17.285 1.00 1.42  ? 82  SER A CA   82  SER A CA   1 
ATOM 1260 C C    . SER A 1 82  ? 39.257 31.626  17.354 1.00 1.42  ? 82  SER A C    82  SER A C    1 
ATOM 1261 O O    . SER A 1 82  ? 39.857 31.653  16.182 1.00 1.42  ? 82  SER A O    82  SER A O    1 
ATOM 1262 C CB   . SER A 1 82  ? 38.240 29.414  17.300 1.00 1.42  ? 82  SER A CB   82  SER A CB   1 
ATOM 1263 O OG   . SER A 1 82  ? 39.058 29.044  18.375 1.00 1.42  ? 82  SER A OG   82  SER A OG   1 
ATOM 1264 H H    . SER A 1 82  ? 37.322 30.773  15.329 1.00 1.42  ? 82  SER A H    82  SER A H    1 
ATOM 1265 H HA   . SER A 1 82  ? 37.341 31.152  18.116 1.00 1.42  ? 82  SER A HA   82  SER A HA   1 
ATOM 1266 H HB2  . SER A 1 82  ? 37.283 28.898  17.372 1.00 1.42  ? 82  SER A HB2  82  SER A 1HB  1 
ATOM 1267 H HB3  . SER A 1 82  ? 38.705 29.110  16.363 1.00 1.42  ? 82  SER A HB3  82  SER A 2HB  1 
ATOM 1268 H HG   . SER A 1 82  ? 38.986 28.089  18.446 1.00 1.42  ? 82  SER A HG   82  SER A HG   1 
ATOM 1269 N N    . PRO A 1 83  ? 39.578 32.125  18.744 1.00 1.51  ? 83  PRO A N    83  PRO A N    1 
ATOM 1270 C CA   . PRO A 1 83  ? 40.866 32.944  18.908 1.00 1.51  ? 83  PRO A CA   83  PRO A CA   1 
ATOM 1271 C C    . PRO A 1 83  ? 42.174 32.187  18.444 1.00 1.51  ? 83  PRO A C    83  PRO A C    1 
ATOM 1272 O O    . PRO A 1 83  ? 43.168 32.962  17.790 1.00 1.51  ? 83  PRO A O    83  PRO A O    1 
ATOM 1273 C CB   . PRO A 1 83  ? 40.900 33.215  20.415 1.00 1.51  ? 83  PRO A CB   83  PRO A CB   1 
ATOM 1274 C CG   . PRO A 1 83  ? 39.464 33.240  20.814 1.00 1.51  ? 83  PRO A CG   83  PRO A CG   1 
ATOM 1275 C CD   . PRO A 1 83  ? 38.837 32.119  20.029 1.00 1.51  ? 83  PRO A CD   83  PRO A CD   1 
ATOM 1276 H HA   . PRO A 1 83  ? 40.774 33.881  18.338 1.00 1.51  ? 83  PRO A HA   83  PRO A HA   1 
ATOM 1277 H HB2  . PRO A 1 83  ? 41.471 32.427  20.927 1.00 1.51  ? 83  PRO A HB2  83  PRO A 1HB  1 
ATOM 1278 H HB3  . PRO A 1 83  ? 41.415 34.166  20.615 1.00 1.51  ? 83  PRO A HB3  83  PRO A 2HB  1 
ATOM 1279 H HG2  . PRO A 1 83  ? 39.369 33.101  21.901 1.00 1.51  ? 83  PRO A HG2  83  PRO A 1HG  1 
ATOM 1280 H HG3  . PRO A 1 83  ? 39.022 34.220  20.580 1.00 1.51  ? 83  PRO A HG3  83  PRO A 2HG  1 
ATOM 1281 H HD2  . PRO A 1 83  ? 38.978 31.170  20.568 1.00 1.51  ? 83  PRO A HD2  83  PRO A 1HD  1 
ATOM 1282 H HD3  . PRO A 1 83  ? 37.767 32.327  19.881 1.00 1.51  ? 83  PRO A HD3  83  PRO A 2HD  1 
ATOM 1283 N N    . SER A 1 84  ? 41.963 30.662  18.464 1.00 1.46  ? 84  SER A N    84  SER A N    1 
ATOM 1284 C CA   . SER A 1 84  ? 43.228 29.959  18.158 1.00 1.46  ? 84  SER A CA   84  SER A CA   1 
ATOM 1285 C C    . SER A 1 84  ? 43.584 30.065  16.653 1.00 1.46  ? 84  SER A C    84  SER A C    1 
ATOM 1286 O O    . SER A 1 84  ? 44.914 29.822  16.336 1.00 1.46  ? 84  SER A O    84  SER A O    1 
ATOM 1287 C CB   . SER A 1 84  ? 43.122 28.501  18.562 1.00 1.46  ? 84  SER A CB   84  SER A CB   1 
ATOM 1288 O OG   . SER A 1 84  ? 42.178 27.830  17.774 1.00 1.46  ? 84  SER A OG   84  SER A OG   1 
ATOM 1289 H H    . SER A 1 84  ? 41.145 30.201  18.851 1.00 1.46  ? 84  SER A H    84  SER A H    1 
ATOM 1290 H HA   . SER A 1 84  ? 44.031 30.426  18.731 1.00 1.46  ? 84  SER A HA   84  SER A HA   1 
ATOM 1291 H HB2  . SER A 1 84  ? 44.095 28.022  18.456 1.00 1.46  ? 84  SER A HB2  84  SER A 1HB  1 
ATOM 1292 H HB3  . SER A 1 84  ? 42.837 28.434  19.611 1.00 1.46  ? 84  SER A HB3  84  SER A 2HB  1 
ATOM 1293 H HG   . SER A 1 84  ? 42.223 28.234  16.904 1.00 1.46  ? 84  SER A HG   84  SER A HG   1 
ATOM 1294 N N    . PHE A 1 85  ? 42.436 30.613  15.774 1.00 1.28  ? 85  PHE A N    85  PHE A N    1 
ATOM 1295 C CA   . PHE A 1 85  ? 42.732 30.674  14.385 1.00 1.28  ? 85  PHE A CA   85  PHE A CA   1 
ATOM 1296 C C    . PHE A 1 85  ? 42.676 32.110  13.871 1.00 1.28  ? 85  PHE A C    85  PHE A C    1 
ATOM 1297 O O    . PHE A 1 85  ? 42.902 32.064  12.550 1.00 1.28  ? 85  PHE A O    85  PHE A O    1 
ATOM 1298 C CB   . PHE A 1 85  ? 41.751 29.794  13.607 1.00 1.28  ? 85  PHE A CB   85  PHE A CB   1 
ATOM 1299 C CG   . PHE A 1 85  ? 41.824 28.338  13.970 1.00 1.28  ? 85  PHE A CG   85  PHE A CG   1 
ATOM 1300 C CD1  . PHE A 1 85  ? 40.838 27.754  14.753 1.00 1.28  ? 85  PHE A CD1  85  PHE A CD1  1 
ATOM 1301 C CD2  . PHE A 1 85  ? 42.877 27.550  13.532 1.00 1.28  ? 85  PHE A CD2  85  PHE A CD2  1 
ATOM 1302 C CE1  . PHE A 1 85  ? 40.904 26.415  15.088 1.00 1.28  ? 85  PHE A CE1  85  PHE A CE1  1 
ATOM 1303 C CE2  . PHE A 1 85  ? 42.945 26.211  13.865 1.00 1.28  ? 85  PHE A CE2  85  PHE A CE2  1 
ATOM 1304 C CZ   . PHE A 1 85  ? 41.956 25.643  14.644 1.00 1.28  ? 85  PHE A CZ   85  PHE A CZ   1 
ATOM 1305 H H    . PHE A 1 85  ? 41.661 31.020  16.035 1.00 1.28  ? 85  PHE A H    85  PHE A H    1 
ATOM 1306 H HA   . PHE A 1 85  ? 43.744 30.299  14.230 1.00 1.28  ? 85  PHE A HA   85  PHE A HA   1 
ATOM 1307 H HB2  . PHE A 1 85  ? 40.733 30.139  13.785 1.00 1.28  ? 85  PHE A HB2  85  PHE A 1HB  1 
ATOM 1308 H HB3  . PHE A 1 85  ? 41.947 29.888  12.540 1.00 1.28  ? 85  PHE A HB3  85  PHE A 2HB  1 
ATOM 1309 H HD1  . PHE A 1 85  ? 40.005 28.364  15.103 1.00 1.28  ? 85  PHE A HD1  85  PHE A HD1  1 
ATOM 1310 H HD2  . PHE A 1 85  ? 43.658 27.999  12.917 1.00 1.28  ? 85  PHE A HD2  85  PHE A HD2  1 
ATOM 1311 H HE1  . PHE A 1 85  ? 40.123 25.969  15.703 1.00 1.28  ? 85  PHE A HE1  85  PHE A HE1  1 
ATOM 1312 H HE2  . PHE A 1 85  ? 43.778 25.603  13.513 1.00 1.28  ? 85  PHE A HE2  85  PHE A HE2  1 
ATOM 1313 H HZ   . PHE A 1 85  ? 42.010 24.588  14.908 1.00 1.28  ? 85  PHE A HZ   85  PHE A HZ   1 
ATOM 1314 N N    . GLN A 1 86  ? 42.642 33.256  14.920 1.00 1.32  ? 86  GLN A N    86  GLN A N    1 
ATOM 1315 C CA   . GLN A 1 86  ? 42.540 34.550  14.393 1.00 1.32  ? 86  GLN A CA   86  GLN A CA   1 
ATOM 1316 C C    . GLN A 1 86  ? 44.074 34.722  13.841 1.00 1.32  ? 86  GLN A C    86  GLN A C    1 
ATOM 1317 O O    . GLN A 1 86  ? 45.271 34.180  14.478 1.00 1.32  ? 86  GLN A O    86  GLN A O    1 
ATOM 1318 C CB   . GLN A 1 86  ? 42.119 35.568  15.455 1.00 1.32  ? 86  GLN A CB   86  GLN A CB   1 
ATOM 1319 C CG   . GLN A 1 86  ? 40.677 35.431  15.913 1.00 1.32  ? 86  GLN A CG   86  GLN A CG   1 
ATOM 1320 C CD   . GLN A 1 86  ? 40.355 36.333  17.089 1.00 1.32  ? 86  GLN A CD   86  GLN A CD   1 
ATOM 1321 O OE1  . GLN A 1 86  ? 41.154 37.194  17.466 1.00 1.32  ? 86  GLN A OE1  86  GLN A OE1  1 
ATOM 1322 N NE2  . GLN A 1 86  ? 39.179 36.141  17.676 1.00 1.32  ? 86  GLN A NE2  86  GLN A NE2  1 
ATOM 1323 H H    . GLN A 1 86  ? 42.707 33.217  15.868 1.00 1.32  ? 86  GLN A H    86  GLN A H    1 
ATOM 1324 H HA   . GLN A 1 86  ? 41.780 34.546  13.612 1.00 1.32  ? 86  GLN A HA   86  GLN A HA   1 
ATOM 1325 H HB2  . GLN A 1 86  ? 42.761 35.467  16.330 1.00 1.32  ? 86  GLN A HB2  86  GLN A 1HB  1 
ATOM 1326 H HB3  . GLN A 1 86  ? 42.254 36.577  15.065 1.00 1.32  ? 86  GLN A HB3  86  GLN A 2HB  1 
ATOM 1327 H HG2  . GLN A 1 86  ? 40.018 35.698  15.087 1.00 1.32  ? 86  GLN A HG2  86  GLN A 1HG  1 
ATOM 1328 H HG3  . GLN A 1 86  ? 40.499 34.399  16.214 1.00 1.32  ? 86  GLN A HG3  86  GLN A 2HG  1 
ATOM 1329 H HE21 . GLN A 1 86  ? 38.911 36.706  18.458 1.00 1.32  ? 86  GLN A HE21 86  GLN A 1HE2 1 
ATOM 1330 H HE22 . GLN A 1 86  ? 38.561 35.431  17.338 1.00 1.32  ? 86  GLN A HE22 86  GLN A 2HE2 1 
ATOM 1331 N N    . GLY A 1 87  ? 43.927 35.437  12.585 1.00 1.33  ? 87  GLY A N    87  GLY A N    1 
ATOM 1332 C CA   . GLY A 1 87  ? 45.259 35.757  11.909 1.00 1.33  ? 87  GLY A CA   87  GLY A CA   1 
ATOM 1333 C C    . GLY A 1 87  ? 45.662 34.659  11.063 1.00 1.33  ? 87  GLY A C    87  GLY A C    1 
ATOM 1334 O O    . GLY A 1 87  ? 46.127 35.234  9.987  1.00 1.33  ? 87  GLY A O    87  GLY A O    1 
ATOM 1335 H H    . GLY A 1 87  ? 43.025 35.741  12.189 1.00 1.33  ? 87  GLY A H    87  GLY A H    1 
ATOM 1336 H HA2  . GLY A 1 87  ? 45.159 36.669  11.321 1.00 1.33  ? 87  GLY A HA2  87  GLY A 1HA  1 
ATOM 1337 H HA3  . GLY A 1 87  ? 46.017 35.945  12.668 1.00 1.33  ? 87  GLY A HA3  87  GLY A 2HA  1 
ATOM 1338 N N    . GLN A 1 88  ? 45.209 33.178  11.338 1.00 1.22  ? 88  GLN A N    88  GLN A N    1 
ATOM 1339 C CA   . GLN A 1 88  ? 45.610 32.201  10.419 1.00 1.22  ? 88  GLN A CA   88  GLN A CA   1 
ATOM 1340 C C    . GLN A 1 88  ? 44.578 31.895  9.354  1.00 1.22  ? 88  GLN A C    88  GLN A C    1 
ATOM 1341 O O    . GLN A 1 88  ? 45.186 31.461  8.300  1.00 1.22  ? 88  GLN A O    88  GLN A O    1 
ATOM 1342 C CB   . GLN A 1 88  ? 45.972 30.923  11.182 1.00 1.22  ? 88  GLN A CB   88  GLN A CB   1 
ATOM 1343 C CG   . GLN A 1 88  ? 47.127 31.086  12.155 1.00 1.22  ? 88  GLN A CG   88  GLN A CG   1 
ATOM 1344 C CD   . GLN A 1 88  ? 47.437 29.804  12.905 1.00 1.22  ? 88  GLN A CD   88  GLN A CD   1 
ATOM 1345 O OE1  . GLN A 1 88  ? 48.600 29.414  13.042 1.00 1.22  ? 88  GLN A OE1  88  GLN A OE1  1 
ATOM 1346 N NE2  . GLN A 1 88  ? 46.397 29.139  13.394 1.00 1.22  ? 88  GLN A NE2  88  GLN A NE2  1 
ATOM 1347 H H    . GLN A 1 88  ? 44.548 32.920  11.983 1.00 1.22  ? 88  GLN A H    88  GLN A H    1 
ATOM 1348 H HA   . GLN A 1 88  ? 46.488 32.566  9.887  1.00 1.22  ? 88  GLN A HA   88  GLN A HA   1 
ATOM 1349 H HB2  . GLN A 1 88  ? 45.105 30.577  11.744 1.00 1.22  ? 88  GLN A HB2  88  GLN A 1HB  1 
ATOM 1350 H HB3  . GLN A 1 88  ? 46.237 30.139  10.473 1.00 1.22  ? 88  GLN A HB3  88  GLN A 2HB  1 
ATOM 1351 H HG2  . GLN A 1 88  ? 48.017 31.381  11.600 1.00 1.22  ? 88  GLN A HG2  88  GLN A 1HG  1 
ATOM 1352 H HG3  . GLN A 1 88  ? 46.870 31.854  12.884 1.00 1.22  ? 88  GLN A HG3  88  GLN A 2HG  1 
ATOM 1353 H HE21 . GLN A 1 88  ? 46.539 28.286  13.898 1.00 1.22  ? 88  GLN A HE21 88  GLN A 1HE2 1 
ATOM 1354 H HE22 . GLN A 1 88  ? 45.470 29.491  13.260 1.00 1.22  ? 88  GLN A HE22 88  GLN A 2HE2 1 
ATOM 1355 N N    . VAL A 1 89  ? 43.127 32.164  9.683  1.00 1.10  ? 89  VAL A N    89  VAL A N    1 
ATOM 1356 C CA   . VAL A 1 89  ? 42.169 31.728  8.721  1.00 1.10  ? 89  VAL A CA   89  VAL A CA   1 
ATOM 1357 C C    . VAL A 1 89  ? 41.170 32.847  8.360  1.00 1.10  ? 89  VAL A C    89  VAL A C    1 
ATOM 1358 O O    . VAL A 1 89  ? 40.829 33.456  9.475  1.00 1.10  ? 89  VAL A O    89  VAL A O    1 
ATOM 1359 C CB   . VAL A 1 89  ? 41.412 30.505  9.273  1.00 1.10  ? 89  VAL A CB   89  VAL A CB   1 
ATOM 1360 C CG1  . VAL A 1 89  ? 40.376 30.938  10.298 1.00 1.10  ? 89  VAL A CG1  89  VAL A CG1  1 
ATOM 1361 C CG2  . VAL A 1 89  ? 40.756 29.744  8.131  1.00 1.10  ? 89  VAL A CG2  89  VAL A CG2  1 
ATOM 1362 H H    . VAL A 1 89  ? 42.983 32.295  10.604 1.00 1.10  ? 89  VAL A H    89  VAL A H    1 
ATOM 1363 H HA   . VAL A 1 89  ? 42.697 31.442  7.811  1.00 1.10  ? 89  VAL A HA   89  VAL A HA   1 
ATOM 1364 H HB   . VAL A 1 89  ? 42.119 29.853  9.786  1.00 1.10  ? 89  VAL A HB   89  VAL A HB   1 
ATOM 1365 H HG11 . VAL A 1 89  ? 39.851 30.061  10.678 1.00 1.10  ? 89  VAL A HG11 89  VAL A 1HG1 1 
ATOM 1366 H HG12 . VAL A 1 89  ? 40.872 31.448  11.124 1.00 1.10  ? 89  VAL A HG12 89  VAL A 2HG1 1 
ATOM 1367 H HG13 . VAL A 1 89  ? 39.660 31.613  9.830  1.00 1.10  ? 89  VAL A HG13 89  VAL A 3HG1 1 
ATOM 1368 H HG21 . VAL A 1 89  ? 40.223 28.880  8.528  1.00 1.10  ? 89  VAL A HG21 89  VAL A 1HG2 1 
ATOM 1369 H HG22 . VAL A 1 89  ? 40.053 30.398  7.614  1.00 1.10  ? 89  VAL A HG22 89  VAL A 2HG2 1 
ATOM 1370 H HG23 . VAL A 1 89  ? 41.521 29.408  7.430  1.00 1.10  ? 89  VAL A HG23 89  VAL A 3HG2 1 
ATOM 1371 N N    . THR A 1 90  ? 40.871 33.121  6.849  1.00 1.07  ? 90  THR A N    90  THR A N    1 
ATOM 1372 C CA   . THR A 1 90  ? 39.979 33.997  6.466  1.00 1.07  ? 90  THR A CA   90  THR A CA   1 
ATOM 1373 C C    . THR A 1 90  ? 38.817 33.342  5.688  1.00 1.07  ? 90  THR A C    90  THR A C    1 
ATOM 1374 O O    . THR A 1 90  ? 39.251 32.665  4.677  1.00 1.07  ? 90  THR A O    90  THR A O    1 
ATOM 1375 C CB   . THR A 1 90  ? 40.698 35.077  5.637  1.00 1.07  ? 90  THR A CB   90  THR A CB   1 
ATOM 1376 O OG1  . THR A 1 90  ? 41.678 35.735  6.451  1.00 1.07  ? 90  THR A OG1  90  THR A OG1  1 
ATOM 1377 C CG2  . THR A 1 90  ? 39.702 36.104  5.119  1.00 1.07  ? 90  THR A CG2  90  THR A CG2  1 
ATOM 1378 H H    . THR A 1 90  ? 41.156 32.408  6.341  1.00 1.07  ? 90  THR A H    90  THR A H    1 
ATOM 1379 H HA   . THR A 1 90  ? 39.534 34.448  7.354  1.00 1.07  ? 90  THR A HA   90  THR A HA   1 
ATOM 1380 H HB   . THR A 1 90  ? 41.203 34.611  4.791  1.00 1.07  ? 90  THR A HB   90  THR A HB   1 
ATOM 1381 H HG1  . THR A 1 90  ? 41.290 35.957  7.301  1.00 1.07  ? 90  THR A HG1  90  THR A HG1  1 
ATOM 1382 H HG21 . THR A 1 90  ? 40.228 36.859  4.535  1.00 1.07  ? 90  THR A HG21 90  THR A 1HG2 1 
ATOM 1383 H HG22 . THR A 1 90  ? 38.963 35.608  4.490  1.00 1.07  ? 90  THR A HG22 90  THR A 2HG2 1 
ATOM 1384 H HG23 . THR A 1 90  ? 39.201 36.581  5.961  1.00 1.07  ? 90  THR A HG23 90  THR A 3HG2 1 
ATOM 1385 N N    . ILE A 1 91  ? 37.354 33.581  6.199  1.00 1.04  ? 91  ILE A N    91  ILE A N    1 
ATOM 1386 C CA   . ILE A 1 91  ? 36.328 33.048  5.574  1.00 1.04  ? 91  ILE A CA   91  ILE A CA   1 
ATOM 1387 C C    . ILE A 1 91  ? 35.727 34.045  4.642  1.00 1.04  ? 91  ILE A C    91  ILE A C    1 
ATOM 1388 O O    . ILE A 1 91  ? 35.598 35.220  5.210  1.00 1.04  ? 91  ILE A O    91  ILE A O    1 
ATOM 1389 C CB   . ILE A 1 91  ? 35.301 32.548  6.607  1.00 1.04  ? 91  ILE A CB   91  ILE A CB   1 
ATOM 1390 C CG1  . ILE A 1 91  ? 35.919 31.460  7.490  1.00 1.04  ? 91  ILE A CG1  91  ILE A CG1  1 
ATOM 1391 C CG2  . ILE A 1 91  ? 34.054 32.028  5.909  1.00 1.04  ? 91  ILE A CG2  91  ILE A CG2  1 
ATOM 1392 C CD1  . ILE A 1 91  ? 35.195 31.253  8.800  1.00 1.04  ? 91  ILE A CD1  91  ILE A CD1  1 
ATOM 1393 H H    . ILE A 1 91  ? 37.197 34.153  6.984  1.00 1.04  ? 91  ILE A H    91  ILE A H    1 
ATOM 1394 H HA   . ILE A 1 91  ? 36.682 32.203  4.985  1.00 1.04  ? 91  ILE A HA   91  ILE A HA   1 
ATOM 1395 H HB   . ILE A 1 91  ? 35.021 33.368  7.268  1.00 1.04  ? 91  ILE A HB   91  ILE A HB   1 
ATOM 1396 H HG12 . ILE A 1 91  ? 35.925 30.514  6.950  1.00 1.04  ? 91  ILE A HG12 91  ILE A 1HG1 1 
ATOM 1397 H HG13 . ILE A 1 91  ? 36.956 31.716  7.711  1.00 1.04  ? 91  ILE A HG13 91  ILE A 2HG1 1 
ATOM 1398 H HG21 . ILE A 1 91  ? 33.340 31.678  6.654  1.00 1.04  ? 91  ILE A HG21 91  ILE A 1HG2 1 
ATOM 1399 H HG22 . ILE A 1 91  ? 33.605 32.829  5.324  1.00 1.04  ? 91  ILE A HG22 91  ILE A 2HG2 1 
ATOM 1400 H HG23 . ILE A 1 91  ? 34.324 31.203  5.250  1.00 1.04  ? 91  ILE A HG23 91  ILE A 3HG2 1 
ATOM 1401 H HD11 . ILE A 1 91  ? 35.691 30.467  9.370  1.00 1.04  ? 91  ILE A HD11 91  ILE A 1HD1 1 
ATOM 1402 H HD12 . ILE A 1 91  ? 35.208 32.180  9.374  1.00 1.04  ? 91  ILE A HD12 91  ILE A 2HD1 1 
ATOM 1403 H HD13 . ILE A 1 91  ? 34.164 30.962  8.604  1.00 1.04  ? 91  ILE A HD13 91  ILE A 3HD1 1 
ATOM 1404 N N    . SER A 1 92  ? 35.477 33.553  3.181  1.00 1.15  ? 92  SER A N    92  SER A N    1 
ATOM 1405 C CA   . SER A 1 92  ? 34.836 34.435  2.284  1.00 1.15  ? 92  SER A CA   92  SER A CA   1 
ATOM 1406 C C    . SER A 1 92  ? 33.545 33.813  1.722  1.00 1.15  ? 92  SER A C    92  SER A C    1 
ATOM 1407 O O    . SER A 1 92  ? 33.771 32.804  0.918  1.00 1.15  ? 92  SER A O    92  SER A O    1 
ATOM 1408 C CB   . SER A 1 92  ? 35.794 34.789  1.164  1.00 1.15  ? 92  SER A CB   92  SER A CB   1 
ATOM 1409 O OG   . SER A 1 92  ? 35.176 35.616  0.216  1.00 1.15  ? 92  SER A OG   92  SER A OG   1 
ATOM 1410 H H    . SER A 1 92  ? 35.576 32.629  2.996  1.00 1.15  ? 92  SER A H    92  SER A H    1 
ATOM 1411 H HA   . SER A 1 92  ? 34.564 35.342  2.825  1.00 1.15  ? 92  SER A HA   92  SER A HA   1 
ATOM 1412 H HB2  . SER A 1 92  ? 36.666 35.295  1.578  1.00 1.15  ? 92  SER A HB2  92  SER A 1HB  1 
ATOM 1413 H HB3  . SER A 1 92  ? 36.144 33.877  0.682  1.00 1.15  ? 92  SER A HB3  92  SER A 2HB  1 
ATOM 1414 H HG   . SER A 1 92  ? 34.399 35.978  0.649  1.00 1.15  ? 92  SER A HG   92  SER A HG   1 
ATOM 1415 N N    . ALA A 1 93  ? 32.203 34.466  2.195  1.00 1.26  ? 93  ALA A N    93  ALA A N    1 
ATOM 1416 C CA   . ALA A 1 93  ? 31.024 33.940  1.704  1.00 1.26  ? 93  ALA A CA   93  ALA A CA   1 
ATOM 1417 C C    . ALA A 1 93  ? 30.419 34.659  0.639  1.00 1.26  ? 93  ALA A C    93  ALA A C    1 
ATOM 1418 O O    . ALA A 1 93  ? 30.039 35.824  1.090  1.00 1.26  ? 93  ALA A O    93  ALA A O    1 
ATOM 1419 C CB   . ALA A 1 93  ? 30.017 33.809  2.838  1.00 1.26  ? 93  ALA A CB   93  ALA A CB   1 
ATOM 1420 H H    . ALA A 1 93  ? 32.192 35.244  2.826  1.00 1.26  ? 93  ALA A H    93  ALA A H    1 
ATOM 1421 H HA   . ALA A 1 93  ? 31.238 32.952  1.295  1.00 1.26  ? 93  ALA A HA   93  ALA A HA   1 
ATOM 1422 H HB1  . ALA A 1 93  ? 29.096 33.368  2.458  1.00 1.26  ? 93  ALA A HB1  93  ALA A 1HB  1 
ATOM 1423 H HB2  . ALA A 1 93  ? 30.430 33.169  3.618  1.00 1.26  ? 93  ALA A HB2  93  ALA A 2HB  1 
ATOM 1424 H HB3  . ALA A 1 93  ? 29.805 34.793  3.251  1.00 1.26  ? 93  ALA A HB3  93  ALA A 3HB  1 
ATOM 1425 N N    . ASP A 1 94  ? 30.326 33.904  -0.712 1.00 1.42  ? 94  ASP A N    94  ASP A N    1 
ATOM 1426 C CA   . ASP A 1 94  ? 29.757 34.552  -1.898 1.00 1.42  ? 94  ASP A CA   94  ASP A CA   1 
ATOM 1427 C C    . ASP A 1 94  ? 28.330 33.952  -1.863 1.00 1.42  ? 94  ASP A C    94  ASP A C    1 
ATOM 1428 O O    . ASP A 1 94  ? 28.142 32.761  -2.570 1.00 1.42  ? 94  ASP A O    94  ASP A O    1 
ATOM 1429 C CB   . ASP A 1 94  ? 30.506 34.223  -3.191 1.00 1.42  ? 94  ASP A CB   94  ASP A CB   1 
ATOM 1430 C CG   . ASP A 1 94  ? 29.945 34.954  -4.403 1.00 1.42  ? 94  ASP A CG   94  ASP A CG   1 
ATOM 1431 O OD1  . ASP A 1 94  ? 28.815 35.379  -4.346 1.00 1.42  ? 94  ASP A OD1  94  ASP A OD1  1 
ATOM 1432 O OD2  . ASP A 1 94  ? 30.652 35.081  -5.375 1.00 1.42  ? 94  ASP A OD2  94  ASP A OD2  1 
ATOM 1433 H H    . ASP A 1 94  ? 30.568 33.018  -0.782 1.00 1.42  ? 94  ASP A H    94  ASP A H    1 
ATOM 1434 H HA   . ASP A 1 94  ? 29.811 35.633  -1.761 1.00 1.42  ? 94  ASP A HA   94  ASP A HA   1 
ATOM 1435 H HB2  . ASP A 1 94  ? 31.558 34.487  -3.080 1.00 1.42  ? 94  ASP A HB2  94  ASP A 1HB  1 
ATOM 1436 H HB3  . ASP A 1 94  ? 30.456 33.149  -3.377 1.00 1.42  ? 94  ASP A HB3  94  ASP A 2HB  1 
ATOM 1437 N N    . LYS A 1 95  ? 27.408 34.858  -1.018 1.00 1.56  ? 95  LYS A N    95  LYS A N    1 
ATOM 1438 C CA   . LYS A 1 95  ? 25.973 34.491  -1.008 1.00 1.56  ? 95  LYS A CA   95  LYS A CA   1 
ATOM 1439 C C    . LYS A 1 95  ? 25.383 34.377  -2.419 1.00 1.56  ? 95  LYS A C    95  LYS A C    1 
ATOM 1440 O O    . LYS A 1 95  ? 24.361 33.444  -2.516 1.00 1.56  ? 95  LYS A O    95  LYS A O    1 
ATOM 1441 C CB   . LYS A 1 95  ? 25.170 35.511  -0.199 1.00 1.56  ? 95  LYS A CB   95  LYS A CB   1 
ATOM 1442 C CG   . LYS A 1 95  ? 23.717 35.121  0.039  1.00 1.56  ? 95  LYS A CG   95  LYS A CG   1 
ATOM 1443 C CD   . LYS A 1 95  ? 23.004 36.150  0.905  1.00 1.56  ? 95  LYS A CD   95  LYS A CD   1 
ATOM 1444 C CE   . LYS A 1 95  ? 21.689 35.606  1.442  1.00 1.56  ? 95  LYS A CE   95  LYS A CE   1 
ATOM 1445 N NZ   . LYS A 1 95  ? 20.740 35.262  0.348  1.00 1.56  ? 95  LYS A NZ   95  LYS A NZ   1 
ATOM 1446 H H    . LYS A 1 95  ? 27.757 35.666  -0.531 1.00 1.56  ? 95  LYS A H    95  LYS A H    1 
ATOM 1447 H HA   . LYS A 1 95  ? 25.870 33.512  -0.539 1.00 1.56  ? 95  LYS A HA   95  LYS A HA   1 
ATOM 1448 H HB2  . LYS A 1 95  ? 25.641 35.656  0.774  1.00 1.56  ? 95  LYS A HB2  95  LYS A 1HB  1 
ATOM 1449 H HB3  . LYS A 1 95  ? 25.179 36.472  -0.713 1.00 1.56  ? 95  LYS A HB3  95  LYS A 2HB  1 
ATOM 1450 H HG2  . LYS A 1 95  ? 23.200 35.043  -0.918 1.00 1.56  ? 95  LYS A HG2  95  LYS A 1HG  1 
ATOM 1451 H HG3  . LYS A 1 95  ? 23.677 34.152  0.534  1.00 1.56  ? 95  LYS A HG3  95  LYS A 2HG  1 
ATOM 1452 H HD2  . LYS A 1 95  ? 23.644 36.425  1.744  1.00 1.56  ? 95  LYS A HD2  95  LYS A 1HD  1 
ATOM 1453 H HD3  . LYS A 1 95  ? 22.803 37.044  0.315  1.00 1.56  ? 95  LYS A HD3  95  LYS A 2HD  1 
ATOM 1454 H HE2  . LYS A 1 95  ? 21.880 34.712  2.034  1.00 1.56  ? 95  LYS A HE2  95  LYS A 1HE  1 
ATOM 1455 H HE3  . LYS A 1 95  ? 21.224 36.350  2.088  1.00 1.56  ? 95  LYS A HE3  95  LYS A 2HE  1 
ATOM 1456 H HZ1  . LYS A 1 95  ? 19.882 34.906  0.745  1.00 1.56  ? 95  LYS A HZ1  95  LYS A 1HZ  1 
ATOM 1457 H HZ2  . LYS A 1 95  ? 20.541 36.089  -0.198 1.00 1.56  ? 95  LYS A HZ2  95  LYS A 2HZ  1 
ATOM 1458 H HZ3  . LYS A 1 95  ? 21.153 34.558  -0.248 1.00 1.56  ? 95  LYS A HZ3  95  LYS A 3HZ  1 
ATOM 1459 N N    . SER A 1 96  ? 26.029 35.289  -3.470 1.00 1.63  ? 96  SER A N    96  SER A N    1 
ATOM 1460 C CA   . SER A 1 96  ? 25.216 35.119  -4.751 1.00 1.63  ? 96  SER A CA   96  SER A CA   1 
ATOM 1461 C C    . SER A 1 96  ? 25.372 33.750  -5.428 1.00 1.63  ? 96  SER A C    96  SER A C    1 
ATOM 1462 O O    . SER A 1 96  ? 24.190 33.206  -5.971 1.00 1.63  ? 96  SER A O    96  SER A O    1 
ATOM 1463 C CB   . SER A 1 96  ? 25.598 36.188  -5.757 1.00 1.63  ? 96  SER A CB   96  SER A CB   1 
ATOM 1464 O OG   . SER A 1 96  ? 26.901 35.987  -6.232 1.00 1.63  ? 96  SER A OG   96  SER A OG   1 
ATOM 1465 H H    . SER A 1 96  ? 26.833 35.888  -3.322 1.00 1.63  ? 96  SER A H    96  SER A H    1 
ATOM 1466 H HA   . SER A 1 96  ? 24.158 35.228  -4.507 1.00 1.63  ? 96  SER A HA   96  SER A HA   1 
ATOM 1467 H HB2  . SER A 1 96  ? 24.897 36.170  -6.591 1.00 1.63  ? 96  SER A HB2  96  SER A 1HB  1 
ATOM 1468 H HB3  . SER A 1 96  ? 25.526 37.169  -5.290 1.00 1.63  ? 96  SER A HB3  96  SER A 2HB  1 
ATOM 1469 H HG   . SER A 1 96  ? 27.427 35.743  -5.467 1.00 1.63  ? 96  SER A HG   96  SER A HG   1 
ATOM 1470 N N    . ILE A 1 97  ? 26.686 33.006  -5.079 1.00 1.58  ? 97  ILE A N    97  ILE A N    1 
ATOM 1471 C CA   . ILE A 1 97  ? 26.747 31.712  -5.790 1.00 1.58  ? 97  ILE A CA   97  ILE A CA   1 
ATOM 1472 C C    . ILE A 1 97  ? 26.606 30.574  -4.655 1.00 1.58  ? 97  ILE A C    97  ILE A C    1 
ATOM 1473 O O    . ILE A 1 97  ? 26.899 29.463  -4.809 1.00 1.58  ? 97  ILE A O    97  ILE A O    1 
ATOM 1474 C CB   . ILE A 1 97  ? 28.058 31.565  -6.584 1.00 1.58  ? 97  ILE A CB   97  ILE A CB   1 
ATOM 1475 C CG1  . ILE A 1 97  ? 29.263 31.633  -5.642 1.00 1.58  ? 97  ILE A CG1  97  ILE A CG1  1 
ATOM 1476 C CG2  . ILE A 1 97  ? 28.154 32.641  -7.655 1.00 1.58  ? 97  ILE A CG2  97  ILE A CG2  1 
ATOM 1477 C CD1  . ILE A 1 97  ? 30.576 31.282  -6.304 1.00 1.58  ? 97  ILE A CD1  97  ILE A CD1  1 
ATOM 1478 H H    . ILE A 1 97  ? 27.224 33.148  -4.284 1.00 1.58  ? 97  ILE A H    97  ILE A H    1 
ATOM 1479 H HA   . ILE A 1 97  ? 25.917 31.666  -6.494 1.00 1.58  ? 97  ILE A HA   97  ILE A HA   1 
ATOM 1480 H HB   . ILE A 1 97  ? 28.086 30.587  -7.062 1.00 1.58  ? 97  ILE A HB   97  ILE A HB   1 
ATOM 1481 H HG12 . ILE A 1 97  ? 29.346 32.639  -5.231 1.00 1.58  ? 97  ILE A HG12 97  ILE A 1HG1 1 
ATOM 1482 H HG13 . ILE A 1 97  ? 29.110 30.950  -4.806 1.00 1.58  ? 97  ILE A HG13 97  ILE A 2HG1 1 
ATOM 1483 H HG21 . ILE A 1 97  ? 29.087 32.523  -8.206 1.00 1.58  ? 97  ILE A HG21 97  ILE A 1HG2 1 
ATOM 1484 H HG22 . ILE A 1 97  ? 27.313 32.547  -8.341 1.00 1.58  ? 97  ILE A HG22 97  ILE A 2HG2 1 
ATOM 1485 H HG23 . ILE A 1 97  ? 28.132 33.625  -7.186 1.00 1.58  ? 97  ILE A HG23 97  ILE A 3HG2 1 
ATOM 1486 H HD11 . ILE A 1 97  ? 31.382 31.352  -5.573 1.00 1.58  ? 97  ILE A HD11 97  ILE A 1HD1 1 
ATOM 1487 H HD12 . ILE A 1 97  ? 30.526 30.264  -6.693 1.00 1.58  ? 97  ILE A HD12 97  ILE A 2HD1 1 
ATOM 1488 H HD13 . ILE A 1 97  ? 30.767 31.974  -7.122 1.00 1.58  ? 97  ILE A HD13 97  ILE A 3HD1 1 
ATOM 1489 N N    . ASN A 1 98  ? 26.208 30.799  -3.471 1.00 1.48  ? 98  ASN A N    98  ASN A N    1 
ATOM 1490 C CA   . ASN A 1 98  ? 25.997 29.662  -2.576 1.00 1.48  ? 98  ASN A CA   98  ASN A CA   1 
ATOM 1491 C C    . ASN A 1 98  ? 27.308 28.978  -2.355 1.00 1.48  ? 98  ASN A C    98  ASN A C    1 
ATOM 1492 O O    . ASN A 1 98  ? 27.116 27.786  -1.816 1.00 1.48  ? 98  ASN A O    98  ASN A O    1 
ATOM 1493 C CB   . ASN A 1 98  ? 24.970 28.692  -3.130 1.00 1.48  ? 98  ASN A CB   98  ASN A CB   1 
ATOM 1494 C CG   . ASN A 1 98  ? 23.903 29.378  -3.937 1.00 1.48  ? 98  ASN A CG   98  ASN A CG   1 
ATOM 1495 O OD1  . ASN A 1 98  ? 23.569 30.542  -3.685 1.00 1.48  ? 98  ASN A OD1  98  ASN A OD1  1 
ATOM 1496 N ND2  . ASN A 1 98  ? 23.362 28.680  -4.903 1.00 1.48  ? 98  ASN A ND2  98  ASN A ND2  1 
ATOM 1497 H H    . ASN A 1 98  ? 26.445 31.697  -3.103 1.00 1.48  ? 98  ASN A H    98  ASN A H    1 
ATOM 1498 H HA   . ASN A 1 98  ? 25.627 30.038  -1.621 1.00 1.48  ? 98  ASN A HA   98  ASN A HA   1 
ATOM 1499 H HB2  . ASN A 1 98  ? 25.468 27.954  -3.760 1.00 1.48  ? 98  ASN A HB2  98  ASN A 1HB  1 
ATOM 1500 H HB3  . ASN A 1 98  ? 24.497 28.154  -2.308 1.00 1.48  ? 98  ASN A HB3  98  ASN A 2HB  1 
ATOM 1501 H HD21 . ASN A 1 98  ? 22.647 29.086  -5.473 1.00 1.48  ? 98  ASN A HD21 98  ASN A 1HD2 1 
ATOM 1502 H HD22 . ASN A 1 98  ? 23.664 27.742  -5.071 1.00 1.48  ? 98  ASN A HD22 98  ASN A 2HD2 1 
ATOM 1503 N N    . THR A 1 99  ? 28.550 29.890  -2.491 1.00 1.36  ? 99  THR A N    99  THR A N    1 
ATOM 1504 C CA   . THR A 1 99  ? 29.833 29.221  -2.161 1.00 1.36  ? 99  THR A CA   99  THR A CA   1 
ATOM 1505 C C    . THR A 1 99  ? 30.611 29.979  -1.079 1.00 1.36  ? 99  THR A C    99  THR A C    1 
ATOM 1506 O O    . THR A 1 99  ? 30.741 31.246  -1.435 1.00 1.36  ? 99  THR A O    99  THR A O    1 
ATOM 1507 C CB   . THR A 1 99  ? 30.720 29.072  -3.411 1.00 1.36  ? 99  THR A CB   99  THR A CB   1 
ATOM 1508 O OG1  . THR A 1 99  ? 29.995 28.377  -4.434 1.00 1.36  ? 99  THR A OG1  99  THR A OG1  1 
ATOM 1509 C CG2  . THR A 1 99  ? 31.986 28.298  -3.077 1.00 1.36  ? 99  THR A CG2  99  THR A CG2  1 
ATOM 1510 H H    . THR A 1 99  ? 28.443 30.877  -2.550 1.00 1.36  ? 99  THR A H    99  THR A H    1 
ATOM 1511 H HA   . THR A 1 99  ? 29.614 28.225  -1.775 1.00 1.36  ? 99  THR A HA   99  THR A HA   1 
ATOM 1512 H HB   . THR A 1 99  ? 30.992 30.059  -3.784 1.00 1.36  ? 99  THR A HB   99  THR A HB   1 
ATOM 1513 H HG1  . THR A 1 99  ? 29.218 28.887  -4.677 1.00 1.36  ? 99  THR A HG1  99  THR A HG1  1 
ATOM 1514 H HG21 . THR A 1 99  ? 32.600 28.202  -3.972 1.00 1.36  ? 99  THR A HG21 99  THR A 1HG2 1 
ATOM 1515 H HG22 . THR A 1 99  ? 32.545 28.829  -2.308 1.00 1.36  ? 99  THR A HG22 99  THR A 2HG2 1 
ATOM 1516 H HG23 . THR A 1 99  ? 31.720 27.306  -2.713 1.00 1.36  ? 99  THR A HG23 99  THR A 3HG2 1 
ATOM 1517 N N    . ALA A 1 100 ? 31.077 29.134  0.079  1.00 1.22  ? 100 ALA A N    100 ALA A N    1 
ATOM 1518 C CA   . ALA A 1 100 ? 31.814 29.611  1.141  1.00 1.22  ? 100 ALA A CA   100 ALA A CA   1 
ATOM 1519 C C    . ALA A 1 100 ? 33.227 29.088  1.007  1.00 1.22  ? 100 ALA A C    100 ALA A C    1 
ATOM 1520 O O    . ALA A 1 100 ? 33.188 27.792  0.991  1.00 1.22  ? 100 ALA A O    100 ALA A O    1 
ATOM 1521 C CB   . ALA A 1 100 ? 31.171 29.195  2.456  1.00 1.22  ? 100 ALA A CB   100 ALA A CB   1 
ATOM 1522 H H    . ALA A 1 100 ? 31.041 28.213  -0.009 1.00 1.22  ? 100 ALA A H    100 ALA A H    1 
ATOM 1523 H HA   . ALA A 1 100 ? 31.828 30.699  1.082  1.00 1.22  ? 100 ALA A HA   100 ALA A HA   1 
ATOM 1524 H HB1  . ALA A 1 100 ? 31.759 29.582  3.287  1.00 1.22  ? 100 ALA A HB1  100 ALA A 1HB  1 
ATOM 1525 H HB2  . ALA A 1 100 ? 30.159 29.596  2.509  1.00 1.22  ? 100 ALA A HB2  100 ALA A 2HB  1 
ATOM 1526 H HB3  . ALA A 1 100 ? 31.133 28.108  2.514  1.00 1.22  ? 100 ALA A HB3  100 ALA A 3HB  1 
ATOM 1527 N N    . TYR A 1 101 ? 34.350 30.122  1.014  1.00 1.11  ? 101 TYR A N    101 TYR A N    1 
ATOM 1528 C CA   . TYR A 1 101 ? 35.686 29.709  0.898  1.00 1.11  ? 101 TYR A CA   101 TYR A CA   1 
ATOM 1529 C C    . TYR A 1 101 ? 36.330 29.914  2.301  1.00 1.11  ? 101 TYR A C    101 TYR A C    1 
ATOM 1530 O O    . TYR A 1 101 ? 36.123 30.790  3.070  1.00 1.11  ? 101 TYR A O    101 TYR A O    1 
ATOM 1531 C CB   . TYR A 1 101 ? 36.402 30.496  -0.201 1.00 1.11  ? 101 TYR A CB   101 TYR A CB   1 
ATOM 1532 C CG   . TYR A 1 101 ? 35.806 30.303  -1.578 1.00 1.11  ? 101 TYR A CG   101 TYR A CG   1 
ATOM 1533 C CD1  . TYR A 1 101 ? 34.718 31.067  -1.976 1.00 1.11  ? 101 TYR A CD1  101 TYR A CD1  1 
ATOM 1534 C CD2  . TYR A 1 101 ? 36.345 29.362  -2.442 1.00 1.11  ? 101 TYR A CD2  101 TYR A CD2  1 
ATOM 1535 C CE1  . TYR A 1 101 ? 34.173 30.890  -3.233 1.00 1.11  ? 101 TYR A CE1  101 TYR A CE1  1 
ATOM 1536 C CE2  . TYR A 1 101 ? 35.800 29.186  -3.699 1.00 1.11  ? 101 TYR A CE2  101 TYR A CE2  1 
ATOM 1537 C CZ   . TYR A 1 101 ? 34.719 29.946  -4.095 1.00 1.11  ? 101 TYR A CZ   101 TYR A CZ   1 
ATOM 1538 O OH   . TYR A 1 101 ? 34.176 29.770  -5.347 1.00 1.11  ? 101 TYR A OH   101 TYR A OH   1 
ATOM 1539 H H    . TYR A 1 101 ? 34.191 31.020  1.105  1.00 1.11  ? 101 TYR A H    101 TYR A H    1 
ATOM 1540 H HA   . TYR A 1 101 ? 35.700 28.651  0.633  1.00 1.11  ? 101 TYR A HA   101 TYR A HA   1 
ATOM 1541 H HB2  . TYR A 1 101 ? 36.374 31.561  0.036  1.00 1.11  ? 101 TYR A HB2  101 TYR A 1HB  1 
ATOM 1542 H HB3  . TYR A 1 101 ? 37.449 30.197  -0.240 1.00 1.11  ? 101 TYR A HB3  101 TYR A 2HB  1 
ATOM 1543 H HD1  . TYR A 1 101 ? 34.294 31.807  -1.296 1.00 1.11  ? 101 TYR A HD1  101 TYR A HD1  1 
ATOM 1544 H HD2  . TYR A 1 101 ? 37.199 28.761  -2.129 1.00 1.11  ? 101 TYR A HD2  101 TYR A HD2  1 
ATOM 1545 H HE1  . TYR A 1 101 ? 33.319 31.491  -3.545 1.00 1.11  ? 101 TYR A HE1  101 TYR A HE1  1 
ATOM 1546 H HE2  . TYR A 1 101 ? 36.224 28.445  -4.378 1.00 1.11  ? 101 TYR A HE2  101 TYR A HE2  1 
ATOM 1547 H HH   . TYR A 1 101 ? 33.374 30.293  -5.423 1.00 1.11  ? 101 TYR A HH   101 TYR A HH   1 
ATOM 1548 N N    . LEU A 1 102 ? 37.125 29.027  2.742  1.00 1.01  ? 102 LEU A N    102 LEU A N    1 
ATOM 1549 C CA   . LEU A 1 102 ? 38.002 29.053  3.929  1.00 1.01  ? 102 LEU A CA   102 LEU A CA   1 
ATOM 1550 C C    . LEU A 1 102 ? 39.418 29.131  3.438  1.00 1.01  ? 102 LEU A C    102 LEU A C    1 
ATOM 1551 O O    . LEU A 1 102 ? 39.786 27.995  2.893  1.00 1.01  ? 102 LEU A O    102 LEU A O    1 
ATOM 1552 C CB   . LEU A 1 102 ? 37.815 27.806  4.803  1.00 1.01  ? 102 LEU A CB   102 LEU A CB   1 
ATOM 1553 C CG   . LEU A 1 102 ? 38.532 27.831  6.159  1.00 1.01  ? 102 LEU A CG   102 LEU A CG   1 
ATOM 1554 C CD1  . LEU A 1 102 ? 37.815 28.794  7.096  1.00 1.01  ? 102 LEU A CD1  102 LEU A CD1  1 
ATOM 1555 C CD2  . LEU A 1 102 ? 38.566 26.426  6.741  1.00 1.01  ? 102 LEU A CD2  102 LEU A CD2  1 
ATOM 1556 H H    . LEU A 1 102 ? 37.200 28.223  2.263  1.00 1.01  ? 102 LEU A H    102 LEU A H    1 
ATOM 1557 H HA   . LEU A 1 102 ? 37.747 29.926  4.529  1.00 1.01  ? 102 LEU A HA   102 LEU A HA   1 
ATOM 1558 H HB2  . LEU A 1 102 ? 36.751 27.672  4.994  1.00 1.01  ? 102 LEU A HB2  102 LEU A 1HB  1 
ATOM 1559 H HB3  . LEU A 1 102 ? 38.177 26.938  4.253  1.00 1.01  ? 102 LEU A HB3  102 LEU A 2HB  1 
ATOM 1560 H HG   . LEU A 1 102 ? 39.551 28.194  6.025  1.00 1.01  ? 102 LEU A HG   102 LEU A HG   1 
ATOM 1561 H HD11 . LEU A 1 102 ? 38.324 28.812  8.059  1.00 1.01  ? 102 LEU A HD11 102 LEU A 1HD1 1 
ATOM 1562 H HD12 . LEU A 1 102 ? 37.822 29.795  6.664  1.00 1.01  ? 102 LEU A HD12 102 LEU A 2HD1 1 
ATOM 1563 H HD13 . LEU A 1 102 ? 36.785 28.466  7.236  1.00 1.01  ? 102 LEU A HD13 102 LEU A 3HD1 1 
ATOM 1564 H HD21 . LEU A 1 102 ? 39.077 26.443  7.705  1.00 1.01  ? 102 LEU A HD21 102 LEU A 1HD2 1 
ATOM 1565 H HD22 . LEU A 1 102 ? 37.547 26.063  6.877  1.00 1.01  ? 102 LEU A HD22 102 LEU A 2HD2 1 
ATOM 1566 H HD23 . LEU A 1 102 ? 39.100 25.763  6.060  1.00 1.01  ? 102 LEU A HD23 102 LEU A 3HD2 1 
ATOM 1567 N N    . GLN A 1 103 ? 40.176 30.481  3.587  1.00 1.09  ? 103 GLN A N    103 GLN A N    1 
ATOM 1568 C CA   . GLN A 1 103 ? 41.443 30.671  3.195  1.00 1.09  ? 103 GLN A CA   103 GLN A CA   1 
ATOM 1569 C C    . GLN A 1 103 ? 42.278 30.356  4.559  1.00 1.09  ? 103 GLN A C    103 GLN A C    1 
ATOM 1570 O O    . GLN A 1 103 ? 41.974 30.903  5.792  1.00 1.09  ? 103 GLN A O    103 GLN A O    1 
ATOM 1571 C CB   . GLN A 1 103 ? 41.618 32.089  2.645  1.00 1.09  ? 103 GLN A CB   103 GLN A CB   1 
ATOM 1572 C CG   . GLN A 1 103 ? 43.007 32.379  2.101  1.00 1.09  ? 103 GLN A CG   103 GLN A CG   1 
ATOM 1573 C CD   . GLN A 1 103 ? 43.099 33.743  1.445  1.00 1.09  ? 103 GLN A CD   103 GLN A CD   1 
ATOM 1574 O OE1  . GLN A 1 103 ? 42.239 34.122  0.644  1.00 1.09  ? 103 GLN A OE1  103 GLN A OE1  1 
ATOM 1575 N NE2  . GLN A 1 103 ? 44.144 34.491  1.780  1.00 1.09  ? 103 GLN A NE2  103 GLN A NE2  1 
ATOM 1576 H H    . GLN A 1 103 ? 39.805 31.192  3.988  1.00 1.09  ? 103 GLN A H    103 GLN A H    1 
ATOM 1577 H HA   . GLN A 1 103 ? 41.671 29.957  2.403  1.00 1.09  ? 103 GLN A HA   103 GLN A HA   1 
ATOM 1578 H HB2  . GLN A 1 103 ? 40.900 32.260  1.843  1.00 1.09  ? 103 GLN A HB2  103 GLN A 1HB  1 
ATOM 1579 H HB3  . GLN A 1 103 ? 41.408 32.813  3.432  1.00 1.09  ? 103 GLN A HB3  103 GLN A 2HB  1 
ATOM 1580 H HG2  . GLN A 1 103 ? 43.722 32.346  2.923  1.00 1.09  ? 103 GLN A HG2  103 GLN A 1HG  1 
ATOM 1581 H HG3  . GLN A 1 103 ? 43.259 31.624  1.356  1.00 1.09  ? 103 GLN A HG3  103 GLN A 2HG  1 
ATOM 1582 H HE21 . GLN A 1 103 ? 44.258 35.401  1.379  1.00 1.09  ? 103 GLN A HE21 103 GLN A 1HE2 1 
ATOM 1583 H HE22 . GLN A 1 103 ? 44.818 34.145  2.433  1.00 1.09  ? 103 GLN A HE22 103 GLN A 2HE2 1 
ATOM 1584 N N    . TRP A 1 104 ? 43.340 29.331  4.273  1.00 1.16  ? 104 TRP A N    104 TRP A N    1 
ATOM 1585 C CA   . TRP A 1 104 ? 44.309 29.124  5.291  1.00 1.16  ? 104 TRP A CA   104 TRP A CA   1 
ATOM 1586 C C    . TRP A 1 104 ? 45.629 29.787  4.934  1.00 1.16  ? 104 TRP A C    104 TRP A C    1 
ATOM 1587 O O    . TRP A 1 104 ? 46.061 29.343  3.791  1.00 1.16  ? 104 TRP A O    104 TRP A O    1 
ATOM 1588 C CB   . TRP A 1 104 ? 44.515 27.625  5.515  1.00 1.16  ? 104 TRP A CB   104 TRP A CB   1 
ATOM 1589 C CG   . TRP A 1 104 ? 43.389 26.970  6.256  1.00 1.16  ? 104 TRP A CG   104 TRP A CG   1 
ATOM 1590 C CD1  . TRP A 1 104 ? 42.357 26.266  5.714  1.00 1.16  ? 104 TRP A CD1  104 TRP A CD1  1 
ATOM 1591 C CD2  . TRP A 1 104 ? 43.176 26.954  7.689  1.00 1.16  ? 104 TRP A CD2  104 TRP A CD2  1 
ATOM 1592 N NE1  . TRP A 1 104 ? 41.518 25.816  6.704  1.00 1.16  ? 104 TRP A NE1  104 TRP A NE1  1 
ATOM 1593 C CE2  . TRP A 1 104 ? 42.006 26.226  7.919  1.00 1.16  ? 104 TRP A CE2  104 TRP A CE2  1 
ATOM 1594 C CE3  . TRP A 1 104 ? 43.876 27.489  8.777  1.00 1.16  ? 104 TRP A CE3  104 TRP A CE3  1 
ATOM 1595 C CZ2  . TRP A 1 104 ? 41.510 26.019  9.196  1.00 1.16  ? 104 TRP A CZ2  104 TRP A CZ2  1 
ATOM 1596 C CZ3  . TRP A 1 104 ? 43.379 27.280  10.059 1.00 1.16  ? 104 TRP A CZ3  104 TRP A CZ3  1 
ATOM 1597 C CH2  . TRP A 1 104 ? 42.227 26.563  10.262 1.00 1.16  ? 104 TRP A CH2  104 TRP A CH2  1 
ATOM 1598 H H    . TRP A 1 104 ? 43.451 28.913  3.447  1.00 1.16  ? 104 TRP A H    104 TRP A H    1 
ATOM 1599 H HA   . TRP A 1 104 ? 43.942 29.572  6.214  1.00 1.16  ? 104 TRP A HA   104 TRP A HA   1 
ATOM 1600 H HB2  . TRP A 1 104 ? 44.629 27.125  4.553  1.00 1.16  ? 104 TRP A HB2  104 TRP A 1HB  1 
ATOM 1601 H HB3  . TRP A 1 104 ? 45.435 27.464  6.078  1.00 1.16  ? 104 TRP A HB3  104 TRP A 2HB  1 
ATOM 1602 H HD1  . TRP A 1 104 ? 42.217 26.086  4.649  1.00 1.16  ? 104 TRP A HD1  104 TRP A HD1  1 
ATOM 1603 H HE1  . TRP A 1 104 ? 40.679 25.272  6.562  1.00 1.16  ? 104 TRP A HE1  104 TRP A HE1  1 
ATOM 1604 H HE3  . TRP A 1 104 ? 44.792 28.057  8.622  1.00 1.16  ? 104 TRP A HE3  104 TRP A HE3  1 
ATOM 1605 H HZ2  . TRP A 1 104 ? 40.597 25.452  9.378  1.00 1.16  ? 104 TRP A HZ2  104 TRP A HZ2  1 
ATOM 1606 H HZ3  . TRP A 1 104 ? 43.929 27.701  10.901 1.00 1.16  ? 104 TRP A HZ3  104 TRP A HZ3  1 
ATOM 1607 H HH2  . TRP A 1 104 ? 41.866 26.417  11.280 1.00 1.16  ? 104 TRP A HH2  104 TRP A HH2  1 
ATOM 1608 N N    . SER A 1 105 ? 46.140 31.039  5.801  1.00 1.26  ? 105 SER A N    105 SER A N    1 
ATOM 1609 C CA   . SER A 1 105 ? 47.293 31.620  5.490  1.00 1.26  ? 105 SER A CA   105 SER A CA   1 
ATOM 1610 C C    . SER A 1 105 ? 48.377 30.870  6.463  1.00 1.26  ? 105 SER A C    105 SER A C    1 
ATOM 1611 O O    . SER A 1 105 ? 48.370 30.549  7.507  1.00 1.26  ? 105 SER A O    105 SER A O    1 
ATOM 1612 C CB   . SER A 1 105 ? 47.171 33.115  5.711  1.00 1.26  ? 105 SER A CB   105 SER A CB   1 
ATOM 1613 O OG   . SER A 1 105 ? 46.224 33.675  4.844  1.00 1.26  ? 105 SER A OG   105 SER A OG   1 
ATOM 1614 H H    . SER A 1 105 ? 45.762 31.019  6.631  1.00 1.26  ? 105 SER A H    105 SER A H    1 
ATOM 1615 H HA   . SER A 1 105 ? 47.504 31.427  4.437  1.00 1.26  ? 105 SER A HA   105 SER A HA   1 
ATOM 1616 H HB2  . SER A 1 105 ? 46.881 33.307  6.744  1.00 1.26  ? 105 SER A HB2  105 SER A 1HB  1 
ATOM 1617 H HB3  . SER A 1 105 ? 48.139 33.587  5.551  1.00 1.26  ? 105 SER A HB3  105 SER A 2HB  1 
ATOM 1618 H HG   . SER A 1 105 ? 45.742 34.325  5.361  1.00 1.26  ? 105 SER A HG   105 SER A HG   1 
ATOM 1619 N N    . SER A 1 106 ? 49.357 30.746  6.147  1.00 1.40  ? 106 SER A N    106 SER A N    1 
ATOM 1620 C CA   . SER A 1 106 ? 50.648 30.224  6.813  1.00 1.40  ? 106 SER A CA   106 SER A CA   1 
ATOM 1621 C C    . SER A 1 106 ? 50.352 28.838  7.462  1.00 1.40  ? 106 SER A C    106 SER A C    1 
ATOM 1622 O O    . SER A 1 106 ? 50.264 28.823  8.848  1.00 1.40  ? 106 SER A O    106 SER A O    1 
ATOM 1623 C CB   . SER A 1 106 ? 51.158 31.186  7.868  1.00 1.40  ? 106 SER A CB   106 SER A CB   1 
ATOM 1624 O OG   . SER A 1 106 ? 51.474 32.429  7.304  1.00 1.40  ? 106 SER A OG   106 SER A OG   1 
ATOM 1625 H H    . SER A 1 106 ? 49.486 30.987  5.174  1.00 1.40  ? 106 SER A H    106 SER A H    1 
ATOM 1626 H HA   . SER A 1 106 ? 51.417 30.123  6.045  1.00 1.40  ? 106 SER A HA   106 SER A HA   1 
ATOM 1627 H HB2  . SER A 1 106 ? 50.399 31.315  8.639  1.00 1.40  ? 106 SER A HB2  106 SER A 1HB  1 
ATOM 1628 H HB3  . SER A 1 106 ? 52.041 30.765  8.347  1.00 1.40  ? 106 SER A HB3  106 SER A 2HB  1 
ATOM 1629 H HG   . SER A 1 106 ? 51.892 32.238  6.461  1.00 1.40  ? 106 SER A HG   106 SER A HG   1 
ATOM 1630 N N    . LEU A 1 107 ? 49.917 27.750  6.415  1.00 1.38  ? 107 LEU A N    107 LEU A N    1 
ATOM 1631 C CA   . LEU A 1 107 ? 49.709 26.468  7.021  1.00 1.38  ? 107 LEU A CA   107 LEU A CA   1 
ATOM 1632 C C    . LEU A 1 107 ? 50.984 25.980  7.790  1.00 1.38  ? 107 LEU A C    107 LEU A C    1 
ATOM 1633 O O    . LEU A 1 107 ? 52.183 26.201  7.247  1.00 1.38  ? 107 LEU A O    107 LEU A O    1 
ATOM 1634 C CB   . LEU A 1 107 ? 49.313 25.459  5.935  1.00 1.38  ? 107 LEU A CB   107 LEU A CB   1 
ATOM 1635 C CG   . LEU A 1 107 ? 47.845 25.498  5.495  1.00 1.38  ? 107 LEU A CG   107 LEU A CG   1 
ATOM 1636 C CD1  . LEU A 1 107 ? 47.638 26.646  4.516  1.00 1.38  ? 107 LEU A CD1  107 LEU A CD1  1 
ATOM 1637 C CD2  . LEU A 1 107 ? 47.469 24.166  4.862  1.00 1.38  ? 107 LEU A CD2  107 LEU A CD2  1 
ATOM 1638 H H    . LEU A 1 107 ? 49.839 27.774  5.474  1.00 1.38  ? 107 LEU A H    107 LEU A H    1 
ATOM 1639 H HA   . LEU A 1 107 ? 48.899 26.555  7.744  1.00 1.38  ? 107 LEU A HA   107 LEU A HA   1 
ATOM 1640 H HB2  . LEU A 1 107 ? 49.928 25.637  5.055  1.00 1.38  ? 107 LEU A HB2  107 LEU A 1HB  1 
ATOM 1641 H HB3  . LEU A 1 107 ? 49.523 24.454  6.302  1.00 1.38  ? 107 LEU A HB3  107 LEU A 2HB  1 
ATOM 1642 H HG   . LEU A 1 107 ? 47.209 25.680  6.362  1.00 1.38  ? 107 LEU A HG   107 LEU A HG   1 
ATOM 1643 H HD11 . LEU A 1 107 ? 46.594 26.673  4.203  1.00 1.38  ? 107 LEU A HD11 107 LEU A 1HD1 1 
ATOM 1644 H HD12 . LEU A 1 107 ? 47.895 27.588  5.001  1.00 1.38  ? 107 LEU A HD12 107 LEU A 2HD1 1 
ATOM 1645 H HD13 . LEU A 1 107 ? 48.274 26.500  3.644  1.00 1.38  ? 107 LEU A HD13 107 LEU A 3HD1 1 
ATOM 1646 H HD21 . LEU A 1 107 ? 46.424 24.193  4.550  1.00 1.38  ? 107 LEU A HD21 107 LEU A 1HD2 1 
ATOM 1647 H HD22 . LEU A 1 107 ? 48.103 23.983  3.994  1.00 1.38  ? 107 LEU A HD22 107 LEU A 2HD2 1 
ATOM 1648 H HD23 . LEU A 1 107 ? 47.609 23.365  5.589  1.00 1.38  ? 107 LEU A HD23 107 LEU A 3HD2 1 
ATOM 1649 N N    . LYS A 1 108 ? 50.653 25.315  9.180  1.00 1.49  ? 108 LYS A N    108 LYS A N    1 
ATOM 1650 C CA   . LYS A 1 108 ? 51.542 24.797  10.004 1.00 1.49  ? 108 LYS A CA   108 LYS A CA   1 
ATOM 1651 C C    . LYS A 1 108 ? 51.093 23.279  10.092 1.00 1.49  ? 108 LYS A C    108 LYS A C    1 
ATOM 1652 O O    . LYS A 1 108 ? 49.859 22.903  9.522  1.00 1.49  ? 108 LYS A O    108 LYS A O    1 
ATOM 1653 C CB   . LYS A 1 108 ? 51.527 25.548  11.337 1.00 1.49  ? 108 LYS A CB   108 LYS A CB   1 
ATOM 1654 C CG   . LYS A 1 108 ? 51.938 27.011  11.239 1.00 1.49  ? 108 LYS A CG   108 LYS A CG   1 
ATOM 1655 C CD   . LYS A 1 108 ? 51.717 27.737  12.558 1.00 1.49  ? 108 LYS A CD   108 LYS A CD   1 
ATOM 1656 C CE   . LYS A 1 108 ? 51.892 29.240  12.400 1.00 1.49  ? 108 LYS A CE   108 LYS A CE   1 
ATOM 1657 N NZ   . LYS A 1 108 ? 50.804 29.844  11.584 1.00 1.49  ? 108 LYS A NZ   108 LYS A NZ   1 
ATOM 1658 H H    . LYS A 1 108 ? 49.686 25.229  9.448  1.00 1.49  ? 108 LYS A H    108 LYS A H    1 
ATOM 1659 H HA   . LYS A 1 108 ? 52.531 24.899  9.555  1.00 1.49  ? 108 LYS A HA   108 LYS A HA   1 
ATOM 1660 H HB2  . LYS A 1 108 ? 50.525 25.510  11.765 1.00 1.49  ? 108 LYS A HB2  108 LYS A 1HB  1 
ATOM 1661 H HB3  . LYS A 1 108 ? 52.202 25.057  12.038 1.00 1.49  ? 108 LYS A HB3  108 LYS A 2HB  1 
ATOM 1662 H HG2  . LYS A 1 108 ? 52.993 27.076  10.971 1.00 1.49  ? 108 LYS A HG2  108 LYS A 1HG  1 
ATOM 1663 H HG3  . LYS A 1 108 ? 51.353 27.502  10.462 1.00 1.49  ? 108 LYS A HG3  108 LYS A 2HG  1 
ATOM 1664 H HD2  . LYS A 1 108 ? 50.709 27.532  12.922 1.00 1.49  ? 108 LYS A HD2  108 LYS A 1HD  1 
ATOM 1665 H HD3  . LYS A 1 108 ? 52.431 27.373  13.297 1.00 1.49  ? 108 LYS A HD3  108 LYS A 2HD  1 
ATOM 1666 H HE2  . LYS A 1 108 ? 51.896 29.710  13.382 1.00 1.49  ? 108 LYS A HE2  108 LYS A 1HE  1 
ATOM 1667 H HE3  . LYS A 1 108 ? 52.847 29.446  11.919 1.00 1.49  ? 108 LYS A HE3  108 LYS A 2HE  1 
ATOM 1668 H HZ1  . LYS A 1 108 ? 50.957 30.839  11.503 1.00 1.49  ? 108 LYS A HZ1  108 LYS A 1HZ  1 
ATOM 1669 H HZ2  . LYS A 1 108 ? 50.803 29.428  10.663 1.00 1.49  ? 108 LYS A HZ2  108 LYS A 2HZ  1 
ATOM 1670 H HZ3  . LYS A 1 108 ? 49.914 29.676  12.030 1.00 1.49  ? 108 LYS A HZ3  108 LYS A 3HZ  1 
ATOM 1671 N N    . ALA A 1 109 ? 52.198 22.445  10.726 1.00 1.64  ? 109 ALA A N    109 ALA A N    1 
ATOM 1672 C CA   . ALA A 1 109 ? 51.863 21.038  10.937 1.00 1.64  ? 109 ALA A CA   109 ALA A CA   1 
ATOM 1673 C C    . ALA A 1 109 ? 50.640 20.834  11.826 1.00 1.64  ? 109 ALA A C    109 ALA A C    1 
ATOM 1674 O O    . ALA A 1 109 ? 49.819 19.725  11.556 1.00 1.64  ? 109 ALA A O    109 ALA A O    1 
ATOM 1675 C CB   . ALA A 1 109 ? 53.058 20.308  11.531 1.00 1.64  ? 109 ALA A CB   109 ALA A CB   1 
ATOM 1676 H H    . ALA A 1 109 ? 53.091 22.838  10.989 1.00 1.64  ? 109 ALA A H    109 ALA A H    1 
ATOM 1677 H HA   . ALA A 1 109 ? 51.620 20.599  9.970  1.00 1.64  ? 109 ALA A HA   109 ALA A HA   1 
ATOM 1678 H HB1  . ALA A 1 109 ? 52.810 19.256  11.671 1.00 1.64  ? 109 ALA A HB1  109 ALA A 1HB  1 
ATOM 1679 H HB2  . ALA A 1 109 ? 53.909 20.393  10.856 1.00 1.64  ? 109 ALA A HB2  109 ALA A 2HB  1 
ATOM 1680 H HB3  . ALA A 1 109 ? 53.314 20.750  12.493 1.00 1.64  ? 109 ALA A HB3  109 ALA A 3HB  1 
ATOM 1681 N N    . SER A 1 110 ? 50.518 22.002  12.775 1.00 1.57  ? 110 SER A N    110 SER A N    1 
ATOM 1682 C CA   . SER A 1 110 ? 49.282 21.832  13.743 1.00 1.57  ? 110 SER A CA   110 SER A CA   1 
ATOM 1683 C C    . SER A 1 110 ? 47.954 21.950  12.979 1.00 1.57  ? 110 SER A C    110 SER A C    1 
ATOM 1684 O O    . SER A 1 110 ? 46.791 21.634  13.662 1.00 1.57  ? 110 SER A O    110 SER A O    1 
ATOM 1685 C CB   . SER A 1 110 ? 49.287 22.873  14.846 1.00 1.57  ? 110 SER A CB   110 SER A CB   1 
ATOM 1686 O OG   . SER A 1 110 ? 49.091 24.158  14.324 1.00 1.57  ? 110 SER A OG   110 SER A OG   1 
ATOM 1687 H H    . SER A 1 110 ? 51.215 22.747  12.823 1.00 1.57  ? 110 SER A H    110 SER A H    1 
ATOM 1688 H HA   . SER A 1 110 ? 49.338 20.847  14.207 1.00 1.57  ? 110 SER A HA   110 SER A HA   1 
ATOM 1689 H HB2  . SER A 1 110 ? 48.499 22.645  15.564 1.00 1.57  ? 110 SER A HB2  110 SER A 1HB  1 
ATOM 1690 H HB3  . SER A 1 110 ? 50.236 22.834  15.378 1.00 1.57  ? 110 SER A HB3  110 SER A 2HB  1 
ATOM 1691 H HG   . SER A 1 110 ? 48.643 24.038  13.483 1.00 1.57  ? 110 SER A HG   110 SER A HG   1 
ATOM 1692 N N    . ASP A 1 111 ? 48.148 22.453  11.544 1.00 1.45  ? 111 ASP A N    111 ASP A N    1 
ATOM 1693 C CA   . ASP A 1 111 ? 46.807 22.565  10.831 1.00 1.45  ? 111 ASP A CA   111 ASP A CA   1 
ATOM 1694 C C    . ASP A 1 111 ? 46.474 21.344  10.105 1.00 1.45  ? 111 ASP A C    111 ASP A C    1 
ATOM 1695 O O    . ASP A 1 111 ? 45.383 21.579  9.377  1.00 1.45  ? 111 ASP A O    111 ASP A O    1 
ATOM 1696 C CB   . ASP A 1 111 ? 46.779 23.721  9.828  1.00 1.45  ? 111 ASP A CB   111 ASP A CB   1 
ATOM 1697 C CG   . ASP A 1 111 ? 47.037 25.075  10.477 1.00 1.45  ? 111 ASP A CG   111 ASP A CG   1 
ATOM 1698 O OD1  . ASP A 1 111 ? 46.368 25.391  11.432 1.00 1.45  ? 111 ASP A OD1  111 ASP A OD1  1 
ATOM 1699 O OD2  . ASP A 1 111 ? 47.901 25.779  10.011 1.00 1.45  ? 111 ASP A OD2  111 ASP A OD2  1 
ATOM 1700 H H    . ASP A 1 111 ? 48.860 22.556  10.988 1.00 1.45  ? 111 ASP A H    111 ASP A H    1 
ATOM 1701 H HA   . ASP A 1 111 ? 46.033 22.752  11.577 1.00 1.45  ? 111 ASP A HA   111 ASP A HA   1 
ATOM 1702 H HB2  . ASP A 1 111 ? 47.532 23.554  9.059  1.00 1.45  ? 111 ASP A HB2  111 ASP A 1HB  1 
ATOM 1703 H HB3  . ASP A 1 111 ? 45.807 23.751  9.334  1.00 1.45  ? 111 ASP A HB3  111 ASP A 2HB  1 
ATOM 1704 N N    . THR A 1 112 ? 47.494 20.147  10.151 1.00 1.61  ? 112 THR A N    112 THR A N    1 
ATOM 1705 C CA   . THR A 1 112 ? 47.139 18.946  9.468  1.00 1.61  ? 112 THR A CA   112 THR A CA   1 
ATOM 1706 C C    . THR A 1 112 ? 45.849 18.318  10.358 1.00 1.61  ? 112 THR A C    112 THR A C    1 
ATOM 1707 O O    . THR A 1 112 ? 45.888 18.034  11.758 1.00 1.61  ? 112 THR A O    112 THR A O    1 
ATOM 1708 C CB   . THR A 1 112 ? 48.349 17.997  9.379  1.00 1.61  ? 112 THR A CB   112 THR A CB   1 
ATOM 1709 O OG1  . THR A 1 112 ? 49.359 18.583  8.548  1.00 1.61  ? 112 THR A OG1  112 THR A OG1  1 
ATOM 1710 C CG2  . THR A 1 112 ? 47.933 16.656  8.795  1.00 1.61  ? 112 THR A CG2  112 THR A CG2  1 
ATOM 1711 H H    . THR A 1 112 ? 48.258 20.056  10.659 1.00 1.61  ? 112 THR A H    112 THR A H    1 
ATOM 1712 H HA   . THR A 1 112 ? 46.824 19.203  8.457  1.00 1.61  ? 112 THR A HA   112 THR A HA   1 
ATOM 1713 H HB   . THR A 1 112 ? 48.763 17.840  10.375 1.00 1.61  ? 112 THR A HB   112 THR A HB   1 
ATOM 1714 H HG1  . THR A 1 112 ? 50.028 18.996  9.101  1.00 1.61  ? 112 THR A HG1  112 THR A HG1  1 
ATOM 1715 H HG21 . THR A 1 112 ? 48.801 15.998  8.740  1.00 1.61  ? 112 THR A HG21 112 THR A 1HG2 1 
ATOM 1716 H HG22 . THR A 1 112 ? 47.173 16.202  9.431  1.00 1.61  ? 112 THR A HG22 112 THR A 2HG2 1 
ATOM 1717 H HG23 . THR A 1 112 ? 47.527 16.805  7.795  1.00 1.61  ? 112 THR A HG23 112 THR A 3HG2 1 
ATOM 1718 N N    . ALA A 1 113 ? 44.700 18.273  9.454  1.00 1.69  ? 113 ALA A N    113 ALA A N    1 
ATOM 1719 C CA   . ALA A 1 113 ? 43.530 17.746  10.212 1.00 1.69  ? 113 ALA A CA   113 ALA A CA   1 
ATOM 1720 C C    . ALA A 1 113 ? 42.455 17.623  9.186  1.00 1.69  ? 113 ALA A C    113 ALA A C    1 
ATOM 1721 O O    . ALA A 1 113 ? 42.661 18.334  7.987  1.00 1.69  ? 113 ALA A O    113 ALA A O    1 
ATOM 1722 C CB   . ALA A 1 113 ? 43.100 18.654  11.355 1.00 1.69  ? 113 ALA A CB   113 ALA A CB   1 
ATOM 1723 H H    . ALA A 1 113 ? 44.784 18.499  8.532  1.00 1.69  ? 113 ALA A H    113 ALA A H    1 
ATOM 1724 H HA   . ALA A 1 113 ? 43.811 16.785  10.643 1.00 1.69  ? 113 ALA A HA   113 ALA A HA   1 
ATOM 1725 H HB1  . ALA A 1 113 ? 42.193 18.258  11.812 1.00 1.69  ? 113 ALA A HB1  113 ALA A 1HB  1 
ATOM 1726 H HB2  . ALA A 1 113 ? 43.892 18.699  12.102 1.00 1.69  ? 113 ALA A HB2  113 ALA A 2HB  1 
ATOM 1727 H HB3  . ALA A 1 113 ? 42.905 19.654  10.972 1.00 1.69  ? 113 ALA A HB3  113 ALA A 3HB  1 
ATOM 1728 N N    . ILE A 1 114 ? 41.282 16.943  9.782  1.00 1.68  ? 114 ILE A N    114 ILE A N    1 
ATOM 1729 C CA   . ILE A 1 114 ? 40.033 16.879  8.840  1.00 1.68  ? 114 ILE A CA   114 ILE A CA   1 
ATOM 1730 C C    . ILE A 1 114 ? 39.225 18.136  9.166  1.00 1.68  ? 114 ILE A C    114 ILE A C    1 
ATOM 1731 O O    . ILE A 1 114 ? 38.920 18.583  10.193 1.00 1.68  ? 114 ILE A O    114 ILE A O    1 
ATOM 1732 C CB   . ILE A 1 114 ? 39.157 15.630  9.051  1.00 1.68  ? 114 ILE A CB   114 ILE A CB   1 
ATOM 1733 C CG1  . ILE A 1 114 ? 39.983 14.358  8.847  1.00 1.68  ? 114 ILE A CG1  114 ILE A CG1  1 
ATOM 1734 C CG2  . ILE A 1 114 ? 37.965 15.652  8.107  1.00 1.68  ? 114 ILE A CG2  114 ILE A CG2  1 
ATOM 1735 C CD1  . ILE A 1 114 ? 39.270 13.093  9.268  1.00 1.68  ? 114 ILE A CD1  114 ILE A CD1  1 
ATOM 1736 H H    . ILE A 1 114 ? 41.107 16.722  10.754 1.00 1.68  ? 114 ILE A H    114 ILE A H    1 
ATOM 1737 H HA   . ILE A 1 114 ? 40.379 16.854  7.808  1.00 1.68  ? 114 ILE A HA   114 ILE A HA   1 
ATOM 1738 H HB   . ILE A 1 114 ? 38.794 15.610  10.078 1.00 1.68  ? 114 ILE A HB   114 ILE A HB   1 
ATOM 1739 H HG12 . ILE A 1 114 ? 40.253 14.264  7.796  1.00 1.68  ? 114 ILE A HG12 114 ILE A 1HG1 1 
ATOM 1740 H HG13 . ILE A 1 114 ? 40.910 14.431  9.417  1.00 1.68  ? 114 ILE A HG13 114 ILE A 2HG1 1 
ATOM 1741 H HG21 . ILE A 1 114 ? 37.357 14.762  8.268  1.00 1.68  ? 114 ILE A HG21 114 ILE A 1HG2 1 
ATOM 1742 H HG22 . ILE A 1 114 ? 37.365 16.540  8.298  1.00 1.68  ? 114 ILE A HG22 114 ILE A 2HG2 1 
ATOM 1743 H HG23 . ILE A 1 114 ? 38.318 15.667  7.075  1.00 1.68  ? 114 ILE A HG23 114 ILE A 3HG2 1 
ATOM 1744 H HD11 . ILE A 1 114 ? 39.919 12.234  9.094  1.00 1.68  ? 114 ILE A HD11 114 ILE A 1HD1 1 
ATOM 1745 H HD12 . ILE A 1 114 ? 39.021 13.151  10.328 1.00 1.68  ? 114 ILE A HD12 114 ILE A 2HD1 1 
ATOM 1746 H HD13 . ILE A 1 114 ? 38.356 12.980  8.685  1.00 1.68  ? 114 ILE A HD13 114 ILE A 3HD1 1 
ATOM 1747 N N    . TYR A 1 115 ? 38.910 18.853  8.243  1.00 1.45  ? 115 TYR A N    115 TYR A N    1 
ATOM 1748 C CA   . TYR A 1 115 ? 38.074 20.156  8.209  1.00 1.45  ? 115 TYR A CA   115 TYR A CA   1 
ATOM 1749 C C    . TYR A 1 115 ? 36.650 19.699  7.687  1.00 1.45  ? 115 TYR A C    115 TYR A C    1 
ATOM 1750 O O    . TYR A 1 115 ? 36.666 19.025  6.553  1.00 1.45  ? 115 TYR A O    115 TYR A O    1 
ATOM 1751 C CB   . TYR A 1 115 ? 38.686 21.229  7.307  1.00 1.45  ? 115 TYR A CB   115 TYR A CB   1 
ATOM 1752 C CG   . TYR A 1 115 ? 40.021 21.748  7.794  1.00 1.45  ? 115 TYR A CG   115 TYR A CG   1 
ATOM 1753 C CD1  . TYR A 1 115 ? 40.414 21.526  9.106  1.00 1.45  ? 115 TYR A CD1  115 TYR A CD1  1 
ATOM 1754 C CD2  . TYR A 1 115 ? 40.852 22.444  6.930  1.00 1.45  ? 115 TYR A CD2  115 TYR A CD2  1 
ATOM 1755 C CE1  . TYR A 1 115 ? 41.634 22.000  9.551  1.00 1.45  ? 115 TYR A CE1  115 TYR A CE1  1 
ATOM 1756 C CE2  . TYR A 1 115 ? 42.071 22.917  7.375  1.00 1.45  ? 115 TYR A CE2  115 TYR A CE2  1 
ATOM 1757 C CZ   . TYR A 1 115 ? 42.462 22.697  8.679  1.00 1.45  ? 115 TYR A CZ   115 TYR A CZ   1 
ATOM 1758 O OH   . TYR A 1 115 ? 43.677 23.169  9.123  1.00 1.45  ? 115 TYR A OH   115 TYR A OH   1 
ATOM 1759 H H    . TYR A 1 115 ? 39.161 18.594  7.418  1.00 1.45  ? 115 TYR A H    115 TYR A H    1 
ATOM 1760 H HA   . TYR A 1 115 ? 38.028 20.563  9.220  1.00 1.45  ? 115 TYR A HA   115 TYR A HA   1 
ATOM 1761 H HB2  . TYR A 1 115 ? 38.824 20.826  6.303  1.00 1.45  ? 115 TYR A HB2  115 TYR A 1HB  1 
ATOM 1762 H HB3  . TYR A 1 115 ? 38.002 22.073  7.230  1.00 1.45  ? 115 TYR A HB3  115 TYR A 2HB  1 
ATOM 1763 H HD1  . TYR A 1 115 ? 39.761 20.979  9.786  1.00 1.45  ? 115 TYR A HD1  115 TYR A HD1  1 
ATOM 1764 H HD2  . TYR A 1 115 ? 40.543 22.619  5.899  1.00 1.45  ? 115 TYR A HD2  115 TYR A HD2  1 
ATOM 1765 H HE1  . TYR A 1 115 ? 41.943 21.826  10.582 1.00 1.45  ? 115 TYR A HE1  115 TYR A HE1  1 
ATOM 1766 H HE2  . TYR A 1 115 ? 42.724 23.466  6.695  1.00 1.45  ? 115 TYR A HE2  115 TYR A HE2  1 
ATOM 1767 H HH   . TYR A 1 115 ? 44.011 22.590  9.812  1.00 1.45  ? 115 TYR A HH   115 TYR A HH   1 
ATOM 1768 N N    . TYR A 1 116 ? 35.480 20.005  8.672  1.00 1.45  ? 116 TYR A N    116 TYR A N    1 
ATOM 1769 C CA   . TYR A 1 116 ? 34.228 19.836  8.265  1.00 1.45  ? 116 TYR A CA   116 TYR A CA   1 
ATOM 1770 C C    . TYR A 1 116 ? 33.538 21.214  8.012  1.00 1.45  ? 116 TYR A C    116 TYR A C    1 
ATOM 1771 O O    . TYR A 1 116 ? 33.912 22.192  8.842  1.00 1.45  ? 116 TYR A O    116 TYR A O    1 
ATOM 1772 C CB   . TYR A 1 116 ? 33.503 18.987  9.312  1.00 1.45  ? 116 TYR A CB   116 TYR A CB   1 
ATOM 1773 C CG   . TYR A 1 116 ? 33.978 17.552  9.370  1.00 1.45  ? 116 TYR A CG   116 TYR A CG   1 
ATOM 1774 C CD1  . TYR A 1 116 ? 35.078 17.217  10.145 1.00 1.45  ? 116 TYR A CD1  116 TYR A CD1  1 
ATOM 1775 C CD2  . TYR A 1 116 ? 33.313 16.572  8.647  1.00 1.45  ? 116 TYR A CD2  116 TYR A CD2  1 
ATOM 1776 C CE1  . TYR A 1 116 ? 35.512 15.906  10.198 1.00 1.45  ? 116 TYR A CE1  116 TYR A CE1  1 
ATOM 1777 C CE2  . TYR A 1 116 ? 33.747 15.262  8.700  1.00 1.45  ? 116 TYR A CE2  116 TYR A CE2  1 
ATOM 1778 C CZ   . TYR A 1 116 ? 34.841 14.928  9.472  1.00 1.45  ? 116 TYR A CZ   116 TYR A CZ   1 
ATOM 1779 O OH   . TYR A 1 116 ? 35.273 13.622  9.524  1.00 1.45  ? 116 TYR A OH   116 TYR A OH   1 
ATOM 1780 H H    . TYR A 1 116 ? 35.689 20.451  9.408  1.00 1.45  ? 116 TYR A H    116 TYR A H    1 
ATOM 1781 H HA   . TYR A 1 116 ? 34.243 19.312  7.309  1.00 1.45  ? 116 TYR A HA   116 TYR A HA   1 
ATOM 1782 H HB2  . TYR A 1 116 ? 33.640 19.431  10.299 1.00 1.45  ? 116 TYR A HB2  116 TYR A 1HB  1 
ATOM 1783 H HB3  . TYR A 1 116 ? 32.434 18.984  9.100  1.00 1.45  ? 116 TYR A HB3  116 TYR A 2HB  1 
ATOM 1784 H HD1  . TYR A 1 116 ? 35.601 17.987  10.713 1.00 1.45  ? 116 TYR A HD1  116 TYR A HD1  1 
ATOM 1785 H HD2  . TYR A 1 116 ? 32.449 16.836  8.037  1.00 1.45  ? 116 TYR A HD2  116 TYR A HD2  1 
ATOM 1786 H HE1  . TYR A 1 116 ? 36.376 15.642  10.807 1.00 1.45  ? 116 TYR A HE1  116 TYR A HE1  1 
ATOM 1787 H HE2  . TYR A 1 116 ? 33.225 14.492  8.132  1.00 1.45  ? 116 TYR A HE2  116 TYR A HE2  1 
ATOM 1788 H HH   . TYR A 1 116 ? 35.919 13.528  10.229 1.00 1.45  ? 116 TYR A HH   116 TYR A HH   1 
ATOM 1789 N N    . CYS A 1 117 ? 32.764 21.373  6.649  1.00 1.34  ? 117 CYS A N    117 CYS A N    1 
ATOM 1790 C CA   . CYS A 1 117 ? 31.937 22.456  6.569  1.00 1.34  ? 117 CYS A CA   117 CYS A CA   1 
ATOM 1791 C C    . CYS A 1 117 ? 30.485 22.021  6.995  1.00 1.34  ? 117 CYS A C    117 CYS A C    1 
ATOM 1792 O O    . CYS A 1 117 ? 30.055 20.968  6.278  1.00 1.34  ? 117 CYS A O    117 CYS A O    1 
ATOM 1793 C CB   . CYS A 1 117 ? 31.971 23.009  5.144  1.00 1.34  ? 117 CYS A CB   117 CYS A CB   1 
ATOM 1794 S SG   . CYS A 1 117 ? 30.940 24.474  4.895  1.00 1.34  ? 117 CYS A SG   117 CYS A SG   1 
ATOM 1795 H H    . CYS A 1 117 ? 32.714 20.615  5.982  1.00 1.34  ? 117 CYS A H    117 CYS A H    1 
ATOM 1796 H HA   . CYS A 1 117 ? 32.297 23.218  7.259  1.00 1.34  ? 117 CYS A HA   117 CYS A HA   1 
ATOM 1797 H HB2  . CYS A 1 117 ? 32.996 23.269  4.879  1.00 1.34  ? 117 CYS A HB2  117 CYS A 1HB  1 
ATOM 1798 H HB3  . CYS A 1 117 ? 31.638 22.240  4.447  1.00 1.34  ? 117 CYS A HB3  117 CYS A 2HB  1 
ATOM 1799 H HG   . CYS A 1 117 ? 31.560 25.234  5.793  1.00 1.34  ? 117 CYS A HG   117 CYS A HG   1 
ATOM 1800 N N    . ALA A 1 118 ? 29.882 22.851  8.117  1.00 1.45  ? 118 ALA A N    118 ALA A N    1 
ATOM 1801 C CA   . ALA A 1 118 ? 28.605 22.572  8.532  1.00 1.45  ? 118 ALA A CA   118 ALA A CA   1 
ATOM 1802 C C    . ALA A 1 118 ? 27.765 23.765  8.153  1.00 1.45  ? 118 ALA A C    118 ALA A C    1 
ATOM 1803 O O    . ALA A 1 118 ? 28.127 24.906  8.246  1.00 1.45  ? 118 ALA A O    118 ALA A O    1 
ATOM 1804 C CB   . ALA A 1 118 ? 28.575 22.288  10.027 1.00 1.45  ? 118 ALA A CB   118 ALA A CB   1 
ATOM 1805 H H    . ALA A 1 118 ? 30.311 23.625  8.420  1.00 1.45  ? 118 ALA A H    118 ALA A H    1 
ATOM 1806 H HA   . ALA A 1 118 ? 28.262 21.685  8.000  1.00 1.45  ? 118 ALA A HA   118 ALA A HA   1 
ATOM 1807 H HB1  . ALA A 1 118 ? 27.551 22.079  10.337 1.00 1.45  ? 118 ALA A HB1  118 ALA A 1HB  1 
ATOM 1808 H HB2  . ALA A 1 118 ? 29.204 21.425  10.246 1.00 1.45  ? 118 ALA A HB2  118 ALA A 2HB  1 
ATOM 1809 H HB3  . ALA A 1 118 ? 28.948 23.155  10.569 1.00 1.45  ? 118 ALA A HB3  118 ALA A 3HB  1 
ATOM 1810 N N    . GLY A 1 119 ? 26.524 23.555  7.699  1.00 1.49  ? 119 GLY A N    119 GLY A N    1 
ATOM 1811 C CA   . GLY A 1 119 ? 25.572 24.699  7.418  1.00 1.49  ? 119 GLY A CA   119 GLY A CA   1 
ATOM 1812 C C    . GLY A 1 119 ? 24.287 24.272  7.987  1.00 1.49  ? 119 GLY A C    119 GLY A C    1 
ATOM 1813 O O    . GLY A 1 119 ? 24.220 23.037  7.709  1.00 1.49  ? 119 GLY A O    119 GLY A O    1 
ATOM 1814 H H    . GLY A 1 119 ? 26.283 22.640  7.519  1.00 1.49  ? 119 GLY A H    119 GLY A H    1 
ATOM 1815 H HA2  . GLY A 1 119 ? 25.955 25.612  7.875  1.00 1.49  ? 119 GLY A HA2  119 GLY A 1HA  1 
ATOM 1816 H HA3  . GLY A 1 119 ? 25.522 24.874  6.344  1.00 1.49  ? 119 GLY A HA3  119 GLY A 2HA  1 
ATOM 1817 N N    . GLY A 1 120 ? 23.406 25.343  8.587  1.00 1.77  ? 120 GLY A N    120 GLY A N    1 
ATOM 1818 C CA   . GLY A 1 120 ? 22.199 25.237  9.278  1.00 1.77  ? 120 GLY A CA   120 GLY A CA   1 
ATOM 1819 C C    . GLY A 1 120 ? 21.541 26.642  8.848  1.00 1.77  ? 120 GLY A C    120 GLY A C    1 
ATOM 1820 O O    . GLY A 1 120 ? 22.090 27.652  8.531  1.00 1.77  ? 120 GLY A O    120 GLY A O    1 
ATOM 1821 H H    . GLY A 1 120 ? 23.717 26.185  8.544  1.00 1.77  ? 120 GLY A H    120 GLY A H    1 
ATOM 1822 H HA2  . GLY A 1 120 ? 21.667 24.345  8.946  1.00 1.77  ? 120 GLY A HA2  120 GLY A 1HA  1 
ATOM 1823 H HA3  . GLY A 1 120 ? 22.398 25.115  10.342 1.00 1.77  ? 120 GLY A HA3  120 GLY A 2HA  1 
ATOM 1824 N N    . SER A 1 121 ? 20.363 26.876  9.231  1.00 2.73  ? 121 SER A N    121 SER A N    1 
ATOM 1825 C CA   . SER A 1 121 ? 19.509 28.045  9.167  1.00 2.73  ? 121 SER A CA   121 SER A CA   1 
ATOM 1826 C C    . SER A 1 121 ? 19.030 28.875  10.122 1.00 2.73  ? 121 SER A C    121 SER A C    1 
ATOM 1827 O O    . SER A 1 121 ? 17.796 28.409  9.797  1.00 2.73  ? 121 SER A O    121 SER A O    1 
ATOM 1828 C CB   . SER A 1 121 ? 18.216 27.639  8.487  1.00 2.73  ? 121 SER A CB   121 SER A CB   1 
ATOM 1829 O OG   . SER A 1 121 ? 17.526 28.761  8.010  1.00 2.73  ? 121 SER A OG   121 SER A OG   1 
ATOM 1830 H H    . SER A 1 121 ? 19.898 26.022  9.489  1.00 2.73  ? 121 SER A H    121 SER A H    1 
ATOM 1831 H HA   . SER A 1 121 ? 20.014 28.811  8.578  1.00 2.73  ? 121 SER A HA   121 SER A HA   1 
ATOM 1832 H HG   . SER A 1 121 ? 18.193 29.349  7.648  1.00 2.73  ? 121 SER A HG   121 SER A HG   1 
ATOM 1833 H 1HB  . SER A 1 121 ? 18.437 26.966  7.658  1.00 2.73  ? 121 SER A 1HB  121 SER A 1HB  1 
ATOM 1834 H 2HB  . SER A 1 121 ? 17.589 27.095  9.192  1.00 2.73  ? 121 SER A 2HB  121 SER A 2HB  1 
ATOM 1835 N N    . GLY A 1 122 ? 19.556 29.161  11.584 1.00 4.70  ? 122 GLY A N    122 GLY A N    1 
ATOM 1836 C CA   . GLY A 1 122 ? 20.335 29.070  12.785 1.00 4.70  ? 122 GLY A CA   122 GLY A CA   1 
ATOM 1837 C C    . GLY A 1 122 ? 18.978 28.776  13.815 1.00 4.70  ? 122 GLY A C    122 GLY A C    1 
ATOM 1838 O O    . GLY A 1 122 ? 19.414 29.329  14.891 1.00 4.70  ? 122 GLY A O    122 GLY A O    1 
ATOM 1839 H H    . GLY A 1 122 ? 19.931 30.050  11.512 1.00 4.70  ? 122 GLY A H    122 GLY A H    1 
ATOM 1840 H HA2  . GLY A 1 122 ? 21.071 28.271  12.682 1.00 4.70  ? 122 GLY A HA2  122 GLY A 1HA  1 
ATOM 1841 H HA3  . GLY A 1 122 ? 20.887 29.997  12.932 1.00 4.70  ? 122 GLY A HA3  122 GLY A 2HA  1 
ATOM 1842 N N    . ILE A 1 123 ? 17.306 28.287  13.666 1.00 5.16  ? 123 ILE A N    123 ILE A N    1 
ATOM 1843 C CA   . ILE A 1 123 ? 17.312 28.612  15.161 1.00 5.16  ? 123 ILE A CA   123 ILE A CA   1 
ATOM 1844 C C    . ILE A 1 123 ? 17.412 27.253  15.628 1.00 5.16  ? 123 ILE A C    123 ILE A C    1 
ATOM 1845 O O    . ILE A 1 123 ? 16.408 26.408  15.414 1.00 5.16  ? 123 ILE A O    123 ILE A O    1 
ATOM 1846 C CB   . ILE A 1 123 ? 16.055 29.306  15.717 1.00 5.16  ? 123 ILE A CB   123 ILE A CB   1 
ATOM 1847 C CG1  . ILE A 1 123 ? 15.806 30.627  14.985 1.00 5.16  ? 123 ILE A CG1  123 ILE A CG1  1 
ATOM 1848 C CG2  . ILE A 1 123 ? 16.195 29.541  17.213 1.00 5.16  ? 123 ILE A CG2  123 ILE A CG2  1 
ATOM 1849 C CD1  . ILE A 1 123 ? 14.483 31.274  15.326 1.00 5.16  ? 123 ILE A CD1  123 ILE A CD1  1 
ATOM 1850 H H    . ILE A 1 123 ? 16.772 27.818  12.965 1.00 5.16  ? 123 ILE A H    123 ILE A H    1 
ATOM 1851 H HA   . ILE A 1 123 ? 18.138 29.294  15.363 1.00 5.16  ? 123 ILE A HA   123 ILE A HA   1 
ATOM 1852 H HB   . ILE A 1 123 ? 15.184 28.677  15.538 1.00 5.16  ? 123 ILE A HB   123 ILE A HB   1 
ATOM 1853 H HG12 . ILE A 1 123 ? 16.602 31.331  15.224 1.00 5.16  ? 123 ILE A HG12 123 ILE A 1HG1 1 
ATOM 1854 H HG13 . ILE A 1 123 ? 15.833 30.457  13.908 1.00 5.16  ? 123 ILE A HG13 123 ILE A 2HG1 1 
ATOM 1855 H HG21 . ILE A 1 123 ? 15.298 30.032  17.590 1.00 5.16  ? 123 ILE A HG21 123 ILE A 1HG2 1 
ATOM 1856 H HG22 . ILE A 1 123 ? 16.325 28.586  17.721 1.00 5.16  ? 123 ILE A HG22 123 ILE A 2HG2 1 
ATOM 1857 H HG23 . ILE A 1 123 ? 17.062 30.174  17.403 1.00 5.16  ? 123 ILE A HG23 123 ILE A 3HG2 1 
ATOM 1858 H HD11 . ILE A 1 123 ? 14.378 32.204  14.768 1.00 5.16  ? 123 ILE A HD11 123 ILE A 1HD1 1 
ATOM 1859 H HD12 . ILE A 1 123 ? 13.668 30.598  15.061 1.00 5.16  ? 123 ILE A HD12 123 ILE A 2HD1 1 
ATOM 1860 H HD13 . ILE A 1 123 ? 14.446 31.486  16.393 1.00 5.16  ? 123 ILE A HD13 123 ILE A 3HD1 1 
ATOM 1861 N N    . SER A 1 124 ? 18.872 27.050  16.168 1.00 6.46  ? 124 SER A N    124 SER A N    1 
ATOM 1862 C CA   . SER A 1 124 ? 19.673 26.011  16.837 1.00 6.46  ? 124 SER A CA   124 SER A CA   1 
ATOM 1863 C C    . SER A 1 124 ? 19.838 24.638  16.061 1.00 6.46  ? 124 SER A C    124 SER A C    1 
ATOM 1864 O O    . SER A 1 124 ? 21.145 24.259  15.847 1.00 6.46  ? 124 SER A O    124 SER A O    1 
ATOM 1865 C CB   . SER A 1 124 ? 19.052 25.746  18.195 1.00 6.46  ? 124 SER A CB   124 SER A CB   1 
ATOM 1866 O OG   . SER A 1 124 ? 19.129 26.882  19.012 1.00 6.46  ? 124 SER A OG   124 SER A OG   1 
ATOM 1867 H H    . SER A 1 124 ? 19.399 27.872  16.084 1.00 6.46  ? 124 SER A H    124 SER A H    1 
ATOM 1868 H HA   . SER A 1 124 ? 20.691 26.384  16.961 1.00 6.46  ? 124 SER A HA   124 SER A HA   1 
ATOM 1869 H HB2  . SER A 1 124 ? 18.009 25.457  18.068 1.00 6.46  ? 124 SER A HB2  124 SER A 1HB  1 
ATOM 1870 H HB3  . SER A 1 124 ? 19.567 24.915  18.674 1.00 6.46  ? 124 SER A HB3  124 SER A 2HB  1 
ATOM 1871 H HG   . SER A 1 124 ? 19.710 26.646  19.739 1.00 6.46  ? 124 SER A HG   124 SER A HG   1 
ATOM 1872 N N    . THR A 1 125 ? 18.551 23.993  15.489 1.00 4.36  ? 125 THR A N    125 THR A N    1 
ATOM 1873 C CA   . THR A 1 125 ? 18.588 22.760  14.984 1.00 4.36  ? 125 THR A CA   125 THR A CA   1 
ATOM 1874 C C    . THR A 1 125 ? 17.670 22.674  13.825 1.00 4.36  ? 125 THR A C    125 THR A C    1 
ATOM 1875 O O    . THR A 1 125 ? 17.315 21.412  13.506 1.00 4.36  ? 125 THR A O    125 THR A O    1 
ATOM 1876 C CB   . THR A 1 125 ? 18.221 21.729  16.069 1.00 4.36  ? 125 THR A CB   125 THR A CB   1 
ATOM 1877 O OG1  . THR A 1 125 ? 16.936 22.046  16.618 1.00 4.36  ? 125 THR A OG1  125 THR A OG1  1 
ATOM 1878 C CG2  . THR A 1 125 ? 19.259 21.734  17.181 1.00 4.36  ? 125 THR A CG2  125 THR A CG2  1 
ATOM 1879 H H    . THR A 1 125 ? 17.730 24.441  15.479 1.00 4.36  ? 125 THR A H    125 THR A H    1 
ATOM 1880 H HA   . THR A 1 125 ? 19.601 22.558  14.637 1.00 4.36  ? 125 THR A HA   125 THR A HA   1 
ATOM 1881 H HB   . THR A 1 125 ? 18.177 20.735  15.625 1.00 4.36  ? 125 THR A HB   125 THR A HB   1 
ATOM 1882 H HG1  . THR A 1 125 ? 16.585 22.826  16.181 1.00 4.36  ? 125 THR A HG1  125 THR A HG1  1 
ATOM 1883 H HG21 . THR A 1 125 ? 18.984 20.999  17.938 1.00 4.36  ? 125 THR A HG21 125 THR A 1HG2 1 
ATOM 1884 H HG22 . THR A 1 125 ? 20.236 21.482  16.769 1.00 4.36  ? 125 THR A HG22 125 THR A 2HG2 1 
ATOM 1885 H HG23 . THR A 1 125 ? 19.301 22.723  17.635 1.00 4.36  ? 125 THR A HG23 125 THR A 3HG2 1 
ATOM 1886 N N    . PRO A 1 126 ? 17.988 23.794  12.755 1.00 3.79  ? 126 PRO A N    126 PRO A N    1 
ATOM 1887 C CA   . PRO A 1 126 ? 17.158 23.719  11.483 1.00 3.79  ? 126 PRO A CA   126 PRO A CA   1 
ATOM 1888 C C    . PRO A 1 126 ? 18.103 22.954  10.449 1.00 3.79  ? 126 PRO A C    126 PRO A C    1 
ATOM 1889 O O    . PRO A 1 126 ? 18.763 23.857  9.602  1.00 3.79  ? 126 PRO A O    126 PRO A O    1 
ATOM 1890 C CB   . PRO A 1 126 ? 16.903 25.179  11.096 1.00 3.79  ? 126 PRO A CB   126 PRO A CB   1 
ATOM 1891 C CG   . PRO A 1 126 ? 18.085 25.911  11.632 1.00 3.79  ? 126 PRO A CG   126 PRO A CG   1 
ATOM 1892 C CD   . PRO A 1 126 ? 18.360 25.258  12.960 1.00 3.79  ? 126 PRO A CD   126 PRO A CD   1 
ATOM 1893 H HA   . PRO A 1 126 ? 16.207 23.212  11.701 1.00 3.79  ? 126 PRO A HA   126 PRO A HA   1 
ATOM 1894 H HB2  . PRO A 1 126 ? 16.806 25.267  10.004 1.00 3.79  ? 126 PRO A HB2  126 PRO A 1HB  1 
ATOM 1895 H HB3  . PRO A 1 126 ? 15.954 25.523  11.532 1.00 3.79  ? 126 PRO A HB3  126 PRO A 2HB  1 
ATOM 1896 H HG2  . PRO A 1 126 ? 18.932 25.827  10.936 1.00 3.79  ? 126 PRO A HG2  126 PRO A 1HG  1 
ATOM 1897 H HG3  . PRO A 1 126 ? 17.857 26.983  11.727 1.00 3.79  ? 126 PRO A HG3  126 PRO A 2HG  1 
ATOM 1898 H HD2  . PRO A 1 126 ? 19.427 25.361  13.207 1.00 3.79  ? 126 PRO A HD2  126 PRO A 1HD  1 
ATOM 1899 H HD3  . PRO A 1 126 ? 17.735 25.725  13.736 1.00 3.79  ? 126 PRO A HD3  126 PRO A 2HD  1 
ATOM 1900 N N    . MET A 1 127 ? 18.276 21.529  10.661 1.00 3.43  ? 127 MET A N    127 MET A N    1 
ATOM 1901 C CA   . MET A 1 127 ? 19.225 20.878  9.747  1.00 3.43  ? 127 MET A CA   127 MET A CA   1 
ATOM 1902 C C    . MET A 1 127 ? 20.678 21.310  9.462  1.00 3.43  ? 127 MET A C    127 MET A C    1 
ATOM 1903 O O    . MET A 1 127 ? 21.059 21.635  8.204  1.00 3.43  ? 127 MET A O    127 MET A O    1 
ATOM 1904 C CB   . MET A 1 127 ? 18.513 20.825  8.396  1.00 3.43  ? 127 MET A CB   127 MET A CB   1 
ATOM 1905 C CG   . MET A 1 127 ? 17.239 19.991  8.388  1.00 3.43  ? 127 MET A CG   127 MET A CG   1 
ATOM 1906 S SD   . MET A 1 127 ? 17.548 18.249  8.741  1.00 3.43  ? 127 MET A SD   127 MET A SD   1 
ATOM 1907 C CE   . MET A 1 127 ? 18.439 17.758  7.268  1.00 3.43  ? 127 MET A CE   127 MET A CE   1 
ATOM 1908 H H    . MET A 1 127 ? 17.999 21.195  11.528 1.00 3.43  ? 127 MET A H    127 MET A H    1 
ATOM 1909 H HA   . MET A 1 127 ? 19.432 19.875  10.120 1.00 3.43  ? 127 MET A HA   127 MET A HA   1 
ATOM 1910 H HB2  . MET A 1 127 ? 18.252 21.835  8.083  1.00 3.43  ? 127 MET A HB2  127 MET A 1HB  1 
ATOM 1911 H HB3  . MET A 1 127 ? 19.187 20.413  7.645  1.00 3.43  ? 127 MET A HB3  127 MET A 2HB  1 
ATOM 1912 H HG2  . MET A 1 127 ? 16.547 20.376  9.136  1.00 3.43  ? 127 MET A HG2  127 MET A 1HG  1 
ATOM 1913 H HG3  . MET A 1 127 ? 16.762 20.065  7.411  1.00 3.43  ? 127 MET A HG3  127 MET A 2HG  1 
ATOM 1914 H HE1  . MET A 1 127 ? 18.701 16.702  7.335  1.00 3.43  ? 127 MET A HE1  127 MET A 1HE  1 
ATOM 1915 H HE2  . MET A 1 127 ? 17.812 17.922  6.390  1.00 3.43  ? 127 MET A HE2  127 MET A 2HE  1 
ATOM 1916 H HE3  . MET A 1 127 ? 19.350 18.352  7.179  1.00 3.43  ? 127 MET A HE3  127 MET A 3HE  1 
ATOM 1917 N N    . ASP A 1 128 ? 21.540 20.878  10.728 1.00 2.64  ? 128 ASP A N    128 ASP A N    1 
ATOM 1918 C CA   . ASP A 1 128 ? 22.946 21.202  10.794 1.00 2.64  ? 128 ASP A CA   128 ASP A CA   1 
ATOM 1919 C C    . ASP A 1 128 ? 23.659 19.989  9.985  1.00 2.64  ? 128 ASP A C    128 ASP A C    1 
ATOM 1920 O O    . ASP A 1 128 ? 24.324 18.815  10.442 1.00 2.64  ? 128 ASP A O    128 ASP A O    1 
ATOM 1921 C CB   . ASP A 1 128 ? 23.423 21.313  12.244 1.00 2.64  ? 128 ASP A CB   128 ASP A CB   1 
ATOM 1922 C CG   . ASP A 1 128 ? 24.860 21.803  12.361 1.00 2.64  ? 128 ASP A CG   128 ASP A CG   1 
ATOM 1923 O OD1  . ASP A 1 128 ? 25.334 22.417  11.435 1.00 2.64  ? 128 ASP A OD1  128 ASP A OD1  1 
ATOM 1924 O OD2  . ASP A 1 128 ? 25.469 21.558  13.374 1.00 2.64  ? 128 ASP A OD2  128 ASP A OD2  1 
ATOM 1925 H H    . ASP A 1 128 ? 21.099 20.399  11.498 1.00 2.64  ? 128 ASP A H    128 ASP A H    1 
ATOM 1926 H HA   . ASP A 1 128 ? 23.102 22.166  10.308 1.00 2.64  ? 128 ASP A HA   128 ASP A HA   1 
ATOM 1927 H HB2  . ASP A 1 128 ? 22.775 22.000  12.789 1.00 2.64  ? 128 ASP A HB2  128 ASP A 1HB  1 
ATOM 1928 H HB3  . ASP A 1 128 ? 23.346 20.339  12.728 1.00 2.64  ? 128 ASP A HB3  128 ASP A 2HB  1 
ATOM 1929 N N    . VAL A 1 129 ? 23.467 20.385  8.505  1.00 2.29  ? 129 VAL A N    129 VAL A N    1 
ATOM 1930 C CA   . VAL A 1 129 ? 24.117 19.457  7.550  1.00 2.29  ? 129 VAL A CA   129 VAL A CA   1 
ATOM 1931 C C    . VAL A 1 129 ? 25.607 19.658  7.657  1.00 2.29  ? 129 VAL A C    129 VAL A C    1 
ATOM 1932 O O    . VAL A 1 129 ? 26.005 20.692  6.945  1.00 2.29  ? 129 VAL A O    129 VAL A O    1 
ATOM 1933 C CB   . VAL A 1 129 ? 23.662 19.716  6.102  1.00 2.29  ? 129 VAL A CB   129 VAL A CB   1 
ATOM 1934 C CG1  . VAL A 1 129 ? 24.451 18.847  5.133  1.00 2.29  ? 129 VAL A CG1  129 VAL A CG1  1 
ATOM 1935 C CG2  . VAL A 1 129 ? 22.170 19.450  5.973  1.00 2.29  ? 129 VAL A CG2  129 VAL A CG2  1 
ATOM 1936 H H    . VAL A 1 129 ? 23.215 21.289  8.316  1.00 2.29  ? 129 VAL A H    129 VAL A H    1 
ATOM 1937 H HA   . VAL A 1 129 ? 23.838 18.436  7.814  1.00 2.29  ? 129 VAL A HA   129 VAL A HA   1 
ATOM 1938 H HB   . VAL A 1 129 ? 23.871 20.754  5.845  1.00 2.29  ? 129 VAL A HB   129 VAL A HB   1 
ATOM 1939 H HG11 . VAL A 1 129 ? 24.117 19.043  4.114  1.00 2.29  ? 129 VAL A HG11 129 VAL A 1HG1 1 
ATOM 1940 H HG12 . VAL A 1 129 ? 25.512 19.080  5.217  1.00 2.29  ? 129 VAL A HG12 129 VAL A 2HG1 1 
ATOM 1941 H HG13 . VAL A 1 129 ? 24.288 17.796  5.371  1.00 2.29  ? 129 VAL A HG13 129 VAL A 3HG1 1 
ATOM 1942 H HG21 . VAL A 1 129 ? 21.855 19.636  4.946  1.00 2.29  ? 129 VAL A HG21 129 VAL A 1HG2 1 
ATOM 1943 H HG22 . VAL A 1 129 ? 21.961 18.413  6.235  1.00 2.29  ? 129 VAL A HG22 129 VAL A 2HG2 1 
ATOM 1944 H HG23 . VAL A 1 129 ? 21.624 20.112  6.645  1.00 2.29  ? 129 VAL A HG23 129 VAL A 3HG2 1 
ATOM 1945 N N    . TRP A 1 130 ? 26.321 18.479  8.402  1.00 2.40  ? 130 TRP A N    130 TRP A N    1 
ATOM 1946 C CA   . TRP A 1 130 ? 27.720 18.403  8.516  1.00 2.40  ? 130 TRP A CA   130 TRP A CA   1 
ATOM 1947 C C    . TRP A 1 130 ? 27.899 17.777  7.113  1.00 2.40  ? 130 TRP A C    130 TRP A C    1 
ATOM 1948 O O    . TRP A 1 130 ? 27.202 16.672  6.916  1.00 2.40  ? 130 TRP A O    130 TRP A O    1 
ATOM 1949 C CB   . TRP A 1 130 ? 28.211 17.530  9.672  1.00 2.40  ? 130 TRP A CB   130 TRP A CB   1 
ATOM 1950 C CG   . TRP A 1 130 ? 27.923 18.110  11.024 1.00 2.40  ? 130 TRP A CG   130 TRP A CG   1 
ATOM 1951 C CD1  . TRP A 1 130 ? 27.305 19.295  11.288 1.00 2.40  ? 130 TRP A CD1  130 TRP A CD1  1 
ATOM 1952 C CD2  . TRP A 1 130 ? 28.242 17.528  12.311 1.00 2.40  ? 130 TRP A CD2  130 TRP A CD2  1 
ATOM 1953 N NE1  . TRP A 1 130 ? 27.219 19.492  12.644 1.00 2.40  ? 130 TRP A NE1  130 TRP A NE1  1 
ATOM 1954 C CE2  . TRP A 1 130 ? 27.786 18.420  13.286 1.00 2.40  ? 130 TRP A CE2  130 TRP A CE2  1 
ATOM 1955 C CE3  . TRP A 1 130 ? 28.868 16.340  12.709 1.00 2.40  ? 130 TRP A CE3  130 TRP A CE3  1 
ATOM 1956 C CZ2  . TRP A 1 130 ? 27.935 18.167  14.640 1.00 2.40  ? 130 TRP A CZ2  130 TRP A CZ2  1 
ATOM 1957 C CZ3  . TRP A 1 130 ? 29.017 16.086  14.067 1.00 2.40  ? 130 TRP A CZ3  130 TRP A CZ3  1 
ATOM 1958 C CH2  . TRP A 1 130 ? 28.562 16.975  15.007 1.00 2.40  ? 130 TRP A CH2  130 TRP A CH2  1 
ATOM 1959 H H    . TRP A 1 130 ? 25.545 18.386  9.206  1.00 2.40  ? 130 TRP A H    130 TRP A H    1 
ATOM 1960 H HA   . TRP A 1 130 ? 28.107 19.407  8.693  1.00 2.40  ? 130 TRP A HA   130 TRP A HA   1 
ATOM 1961 H HB2  . TRP A 1 130 ? 27.740 16.549  9.612  1.00 2.40  ? 130 TRP A HB2  130 TRP A 1HB  1 
ATOM 1962 H HB3  . TRP A 1 130 ? 29.287 17.382  9.585  1.00 2.40  ? 130 TRP A HB3  130 TRP A 2HB  1 
ATOM 1963 H HD1  . TRP A 1 130 ? 26.934 19.986  10.532 1.00 2.40  ? 130 TRP A HD1  130 TRP A HD1  1 
ATOM 1964 H HE1  . TRP A 1 130 ? 26.806 20.295  13.096 1.00 2.40  ? 130 TRP A HE1  130 TRP A HE1  1 
ATOM 1965 H HE3  . TRP A 1 130 ? 29.229 15.629  11.966 1.00 2.40  ? 130 TRP A HE3  130 TRP A HE3  1 
ATOM 1966 H HZ2  . TRP A 1 130 ? 27.580 18.861  15.402 1.00 2.40  ? 130 TRP A HZ2  130 TRP A HZ2  1 
ATOM 1967 H HZ3  . TRP A 1 130 ? 29.506 15.159  14.368 1.00 2.40  ? 130 TRP A HZ3  130 TRP A HZ3  1 
ATOM 1968 H HH2  . TRP A 1 130 ? 28.694 16.744  16.064 1.00 2.40  ? 130 TRP A HH2  130 TRP A HH2  1 
ATOM 1969 N N    . GLY A 1 131 ? 28.828 18.525  6.159  1.00 1.99  ? 131 GLY A N    131 GLY A N    1 
ATOM 1970 C CA   . GLY A 1 131 ? 29.119 18.105  4.929  1.00 1.99  ? 131 GLY A CA   131 GLY A CA   1 
ATOM 1971 C C    . GLY A 1 131 ? 30.284 17.034  5.070  1.00 1.99  ? 131 GLY A C    131 GLY A C    1 
ATOM 1972 O O    . GLY A 1 131 ? 30.332 16.361  6.160  1.00 1.99  ? 131 GLY A O    131 GLY A O    1 
ATOM 1973 H H    . GLY A 1 131 ? 29.343 19.321  6.404  1.00 1.99  ? 131 GLY A H    131 GLY A H    1 
ATOM 1974 H HA2  . GLY A 1 131 ? 28.228 17.678  4.469  1.00 1.99  ? 131 GLY A HA2  131 GLY A 1HA  1 
ATOM 1975 H HA3  . GLY A 1 131 ? 29.421 18.954  4.317  1.00 1.99  ? 131 GLY A HA3  131 GLY A 2HA  1 
ATOM 1976 N N    . GLN A 1 132 ? 30.831 16.537  3.872  1.00 2.01  ? 132 GLN A N    132 GLN A N    1 
ATOM 1977 C CA   . GLN A 1 132 ? 31.813 15.565  3.798  1.00 2.01  ? 132 GLN A CA   132 GLN A CA   1 
ATOM 1978 C C    . GLN A 1 132 ? 33.109 16.495  4.341  1.00 2.01  ? 132 GLN A C    132 GLN A C    1 
ATOM 1979 O O    . GLN A 1 132 ? 33.282 17.670  4.333  1.00 2.01  ? 132 GLN A O    132 GLN A O    1 
ATOM 1980 C CB   . GLN A 1 132 ? 31.946 15.009  2.378  1.00 2.01  ? 132 GLN A CB   132 GLN A CB   1 
ATOM 1981 C CG   . GLN A 1 132 ? 30.695 14.321  1.859  1.00 2.01  ? 132 GLN A CG   132 GLN A CG   1 
ATOM 1982 C CD   . GLN A 1 132 ? 30.426 13.004  2.562  1.00 2.01  ? 132 GLN A CD   132 GLN A CD   1 
ATOM 1983 O OE1  . GLN A 1 132 ? 31.228 12.069  2.488  1.00 2.01  ? 132 GLN A OE1  132 GLN A OE1  1 
ATOM 1984 N NE2  . GLN A 1 132 ? 29.292 12.922  3.249  1.00 2.01  ? 132 GLN A NE2  132 GLN A NE2  1 
ATOM 1985 H H    . GLN A 1 132 ? 30.622 17.041  3.029  1.00 2.01  ? 132 GLN A H    132 GLN A H    1 
ATOM 1986 H HA   . GLN A 1 132 ? 31.539 14.744  4.460  1.00 2.01  ? 132 GLN A HA   132 GLN A HA   1 
ATOM 1987 H HB2  . GLN A 1 132 ? 32.194 15.818  1.691  1.00 2.01  ? 132 GLN A HB2  132 GLN A 1HB  1 
ATOM 1988 H HB3  . GLN A 1 132 ? 32.764 14.289  2.344  1.00 2.01  ? 132 GLN A HB3  132 GLN A 2HB  1 
ATOM 1989 H HG2  . GLN A 1 132 ? 29.839 14.976  2.021  1.00 2.01  ? 132 GLN A HG2  132 GLN A 1HG  1 
ATOM 1990 H HG3  . GLN A 1 132 ? 30.817 14.122  0.795  1.00 2.01  ? 132 GLN A HG3  132 GLN A 2HG  1 
ATOM 1991 H HE21 . GLN A 1 132 ? 29.060 12.077  3.734  1.00 2.01  ? 132 GLN A HE21 132 GLN A 1HE2 1 
ATOM 1992 H HE22 . GLN A 1 132 ? 28.669 13.704  3.283  1.00 2.01  ? 132 GLN A HE22 132 GLN A 2HE2 1 
ATOM 1993 N N    . GLY A 1 133 ? 33.852 16.027  5.151  1.00 1.63  ? 133 GLY A N    133 GLY A N    1 
ATOM 1994 C CA   . GLY A 1 133 ? 35.030 16.579  5.639  1.00 1.63  ? 133 GLY A CA   133 GLY A CA   1 
ATOM 1995 C C    . GLY A 1 133 ? 36.048 16.449  4.405  1.00 1.63  ? 133 GLY A C    133 GLY A C    1 
ATOM 1996 O O    . GLY A 1 133 ? 35.849 15.826  3.318  1.00 1.63  ? 133 GLY A O    133 GLY A O    1 
ATOM 1997 H H    . GLY A 1 133 ? 33.655 15.060  5.396  1.00 1.63  ? 133 GLY A H    133 GLY A H    1 
ATOM 1998 H HA2  . GLY A 1 133 ? 34.849 17.609  5.947  1.00 1.63  ? 133 GLY A HA2  133 GLY A 1HA  1 
ATOM 1999 H HA3  . GLY A 1 133 ? 35.349 16.031  6.525  1.00 1.63  ? 133 GLY A HA3  133 GLY A 2HA  1 
ATOM 2000 N N    . THR A 1 134 ? 36.995 17.283  4.500  1.00 1.53  ? 134 THR A N    134 THR A N    1 
ATOM 2001 C CA   . THR A 1 134 ? 38.218 17.454  3.633  1.00 1.53  ? 134 THR A CA   134 THR A CA   1 
ATOM 2002 C C    . THR A 1 134 ? 39.464 17.255  4.557  1.00 1.53  ? 134 THR A C    134 THR A C    1 
ATOM 2003 O O    . THR A 1 134 ? 39.445 17.932  5.718  1.00 1.53  ? 134 THR A O    134 THR A O    1 
ATOM 2004 C CB   . THR A 1 134 ? 38.266 18.833  2.950  1.00 1.53  ? 134 THR A CB   134 THR A CB   1 
ATOM 2005 O OG1  . THR A 1 134 ? 37.102 19.005  2.132  1.00 1.53  ? 134 THR A OG1  134 THR A OG1  1 
ATOM 2006 C CG2  . THR A 1 134 ? 39.511 18.958  2.086  1.00 1.53  ? 134 THR A CG2  134 THR A CG2  1 
ATOM 2007 H H    . THR A 1 134 ? 36.981 17.851  5.203  1.00 1.53  ? 134 THR A H    134 THR A H    1 
ATOM 2008 H HA   . THR A 1 134 ? 38.195 16.697  2.849  1.00 1.53  ? 134 THR A HA   134 THR A HA   1 
ATOM 2009 H HB   . THR A 1 134 ? 38.278 19.615  3.710  1.00 1.53  ? 134 THR A HB   134 THR A HB   1 
ATOM 2010 H HG1  . THR A 1 134 ? 36.574 18.203  2.155  1.00 1.53  ? 134 THR A HG1  134 THR A HG1  1 
ATOM 2011 H HG21 . THR A 1 134 ? 39.529 19.939  1.612  1.00 1.53  ? 134 THR A HG21 134 THR A 1HG2 1 
ATOM 2012 H HG22 . THR A 1 134 ? 40.399 18.839  2.707  1.00 1.53  ? 134 THR A HG22 134 THR A 2HG2 1 
ATOM 2013 H HG23 . THR A 1 134 ? 39.500 18.185  1.319  1.00 1.53  ? 134 THR A HG23 134 THR A 3HG2 1 
ATOM 2014 N N    . THR A 1 135 ? 40.374 16.128  4.100  1.00 1.57  ? 135 THR A N    135 THR A N    1 
ATOM 2015 C CA   . THR A 1 135 ? 41.593 16.046  4.894  1.00 1.57  ? 135 THR A CA   135 THR A CA   1 
ATOM 2016 C C    . THR A 1 135 ? 42.685 16.948  4.329  1.00 1.57  ? 135 THR A C    135 THR A C    1 
ATOM 2017 O O    . THR A 1 135 ? 42.890 16.690  3.050  1.00 1.57  ? 135 THR A O    135 THR A O    1 
ATOM 2018 C CB   . THR A 1 135 ? 42.106 14.596  4.968  1.00 1.57  ? 135 THR A CB   135 THR A CB   1 
ATOM 2019 O OG1  . THR A 1 135 ? 41.102 13.760  5.557  1.00 1.57  ? 135 THR A OG1  135 THR A OG1  1 
ATOM 2020 C CG2  . THR A 1 135 ? 43.376 14.521  5.803  1.00 1.57  ? 135 THR A CG2  135 THR A CG2  1 
ATOM 2021 H H    . THR A 1 135 ? 40.254 16.064  3.117  1.00 1.57  ? 135 THR A H    135 THR A H    1 
ATOM 2022 H HA   . THR A 1 135 ? 41.370 16.383  5.907  1.00 1.57  ? 135 THR A HA   135 THR A HA   1 
ATOM 2023 H HB   . THR A 1 135 ? 42.318 14.233  3.963  1.00 1.57  ? 135 THR A HB   135 THR A HB   1 
ATOM 2024 H HG1  . THR A 1 135 ? 40.647 13.272  4.866  1.00 1.57  ? 135 THR A HG1  135 THR A HG1  1 
ATOM 2025 H HG21 . THR A 1 135 ? 43.724 13.490  5.844  1.00 1.57  ? 135 THR A HG21 135 THR A 1HG2 1 
ATOM 2026 H HG22 . THR A 1 135 ? 44.145 15.147  5.352  1.00 1.57  ? 135 THR A HG22 135 THR A 2HG2 1 
ATOM 2027 H HG23 . THR A 1 135 ? 43.168 14.874  6.813  1.00 1.57  ? 135 THR A HG23 135 THR A 3HG2 1 
ATOM 2028 N N    . VAL A 1 136 ? 43.260 17.928  5.331  1.00 1.45  ? 136 VAL A N    136 VAL A N    1 
ATOM 2029 C CA   . VAL A 1 136 ? 44.359 18.765  4.885  1.00 1.45  ? 136 VAL A CA   136 VAL A CA   1 
ATOM 2030 C C    . VAL A 1 136 ? 45.665 18.170  5.465  1.00 1.45  ? 136 VAL A C    136 VAL A C    1 
ATOM 2031 O O    . VAL A 1 136 ? 45.743 17.927  6.788  1.00 1.45  ? 136 VAL A O    136 VAL A O    1 
ATOM 2032 C CB   . VAL A 1 136 ? 44.167 20.219  5.356  1.00 1.45  ? 136 VAL A CB   136 VAL A CB   1 
ATOM 2033 C CG1  . VAL A 1 136 ? 45.379 21.062  4.989  1.00 1.45  ? 136 VAL A CG1  136 VAL A CG1  1 
ATOM 2034 C CG2  . VAL A 1 136 ? 42.901 20.799  4.743  1.00 1.45  ? 136 VAL A CG2  136 VAL A CG2  1 
ATOM 2035 H H    . VAL A 1 136 ? 42.996 17.955  6.218  1.00 1.45  ? 136 VAL A H    136 VAL A H    1 
ATOM 2036 H HA   . VAL A 1 136 ? 44.381 18.755  3.794  1.00 1.45  ? 136 VAL A HA   136 VAL A HA   1 
ATOM 2037 H HB   . VAL A 1 136 ? 44.084 20.231  6.443  1.00 1.45  ? 136 VAL A HB   136 VAL A HB   1 
ATOM 2038 H HG11 . VAL A 1 136 ? 45.227 22.086  5.329  1.00 1.45  ? 136 VAL A HG11 136 VAL A 1HG1 1 
ATOM 2039 H HG12 . VAL A 1 136 ? 46.267 20.649  5.467  1.00 1.45  ? 136 VAL A HG12 136 VAL A 2HG1 1 
ATOM 2040 H HG13 . VAL A 1 136 ? 45.512 21.056  3.907  1.00 1.45  ? 136 VAL A HG13 136 VAL A 3HG1 1 
ATOM 2041 H HG21 . VAL A 1 136 ? 42.772 21.827  5.081  1.00 1.45  ? 136 VAL A HG21 136 VAL A 1HG2 1 
ATOM 2042 H HG22 . VAL A 1 136 ? 42.982 20.781  3.656  1.00 1.45  ? 136 VAL A HG22 136 VAL A 2HG2 1 
ATOM 2043 H HG23 . VAL A 1 136 ? 42.042 20.204  5.053  1.00 1.45  ? 136 VAL A HG23 136 VAL A 3HG2 1 
ATOM 2044 N N    . THR A 1 137 ? 46.668 17.735  4.362  1.00 1.63  ? 137 THR A N    137 THR A N    1 
ATOM 2045 C CA   . THR A 1 137 ? 47.915 17.232  4.811  1.00 1.63  ? 137 THR A CA   137 THR A CA   1 
ATOM 2046 C C    . THR A 1 137 ? 49.007 18.291  4.556  1.00 1.63  ? 137 THR A C    137 THR A C    1 
ATOM 2047 O O    . THR A 1 137 ? 49.033 18.693  3.290  1.00 1.63  ? 137 THR A O    137 THR A O    1 
ATOM 2048 C CB   . THR A 1 137 ? 48.256 15.906  4.108  1.00 1.63  ? 137 THR A CB   137 THR A CB   1 
ATOM 2049 O OG1  . THR A 1 137 ? 47.275 14.917  4.447  1.00 1.63  ? 137 THR A OG1  137 THR A OG1  1 
ATOM 2050 C CG2  . THR A 1 137 ? 49.632 15.415  4.532  1.00 1.63  ? 137 THR A CG2  137 THR A CG2  1 
ATOM 2051 H H    . THR A 1 137 ? 46.497 18.052  3.505  1.00 1.63  ? 137 THR A H    137 THR A H    1 
ATOM 2052 H HA   . THR A 1 137 ? 47.847 17.048  5.884  1.00 1.63  ? 137 THR A HA   137 THR A HA   1 
ATOM 2053 H HB   . THR A 1 137 ? 48.246 16.053  3.028  1.00 1.63  ? 137 THR A HB   137 THR A HB   1 
ATOM 2054 H HG1  . THR A 1 137 ? 47.053 14.992  5.378  1.00 1.63  ? 137 THR A HG1  137 THR A HG1  1 
ATOM 2055 H HG21 . THR A 1 137 ? 49.856 14.477  4.025  1.00 1.63  ? 137 THR A HG21 137 THR A 1HG2 1 
ATOM 2056 H HG22 . THR A 1 137 ? 50.381 16.160  4.266  1.00 1.63  ? 137 THR A HG22 137 THR A 2HG2 1 
ATOM 2057 H HG23 . THR A 1 137 ? 49.645 15.257  5.610  1.00 1.63  ? 137 THR A HG23 137 THR A 3HG2 1 
ATOM 2058 N N    . VAL A 1 138 ? 49.771 18.683  5.795  1.00 1.65  ? 138 VAL A N    138 VAL A N    1 
ATOM 2059 C CA   . VAL A 1 138 ? 50.883 19.610  5.577  1.00 1.65  ? 138 VAL A CA   138 VAL A CA   1 
ATOM 2060 C C    . VAL A 1 138 ? 52.242 18.857  5.586  1.00 1.65  ? 138 VAL A C    138 VAL A C    1 
ATOM 2061 O O    . VAL A 1 138 ? 52.504 18.311  6.767  1.00 1.65  ? 138 VAL A O    138 VAL A O    1 
ATOM 2062 C CB   . VAL A 1 138 ? 50.883 20.699  6.666  1.00 1.65  ? 138 VAL A CB   138 VAL A CB   1 
ATOM 2063 C CG1  . VAL A 1 138 ? 52.054 21.649  6.469  1.00 1.65  ? 138 VAL A CG1  138 VAL A CG1  1 
ATOM 2064 C CG2  . VAL A 1 138 ? 49.564 21.456  6.641  1.00 1.65  ? 138 VAL A CG2  138 VAL A CG2  1 
ATOM 2065 H H    . VAL A 1 138 ? 49.585 18.271  6.698  1.00 1.65  ? 138 VAL A H    138 VAL A H    1 
ATOM 2066 H HA   . VAL A 1 138 ? 50.752 20.085  4.604  1.00 1.65  ? 138 VAL A HA   138 VAL A HA   1 
ATOM 2067 H HB   . VAL A 1 138 ? 51.013 20.226  7.640  1.00 1.65  ? 138 VAL A HB   138 VAL A HB   1 
ATOM 2068 H HG11 . VAL A 1 138 ? 52.039 22.412  7.247  1.00 1.65  ? 138 VAL A HG11 138 VAL A 1HG1 1 
ATOM 2069 H HG12 . VAL A 1 138 ? 52.989 21.092  6.526  1.00 1.65  ? 138 VAL A HG12 138 VAL A 2HG1 1 
ATOM 2070 H HG13 . VAL A 1 138 ? 51.975 22.127  5.492  1.00 1.65  ? 138 VAL A HG13 138 VAL A 3HG1 1 
ATOM 2071 H HG21 . VAL A 1 138 ? 49.571 22.224  7.414  1.00 1.65  ? 138 VAL A HG21 138 VAL A 1HG2 1 
ATOM 2072 H HG22 . VAL A 1 138 ? 49.431 21.924  5.666  1.00 1.65  ? 138 VAL A HG22 138 VAL A 2HG2 1 
ATOM 2073 H HG23 . VAL A 1 138 ? 48.743 20.763  6.826  1.00 1.65  ? 138 VAL A HG23 138 VAL A 3HG2 1 
ATOM 2074 N N    . SER A 1 139 ? 52.973 18.811  4.216  1.00 1.81  ? 139 SER A N    139 SER A N    1 
ATOM 2075 C CA   . SER A 1 139 ? 54.053 18.055  3.998  1.00 1.81  ? 139 SER A CA   139 SER A CA   1 
ATOM 2076 C C    . SER A 1 139 ? 55.235 19.024  3.916  1.00 1.81  ? 139 SER A C    139 SER A C    1 
ATOM 2077 O O    . SER A 1 139 ? 55.088 20.330  3.511  1.00 1.81  ? 139 SER A O    139 SER A O    1 
ATOM 2078 C CB   . SER A 1 139 ? 53.865 17.245  2.730  1.00 1.81  ? 139 SER A CB   139 SER A CB   1 
ATOM 2079 O OG   . SER A 1 139 ? 53.687 18.082  1.621  1.00 1.81  ? 139 SER A OG   139 SER A OG   1 
ATOM 2080 H H    . SER A 1 139 ? 52.675 19.462  3.642  1.00 1.81  ? 139 SER A H    139 SER A H    1 
ATOM 2081 H HA   . SER A 1 139 ? 54.173 17.373  4.840  1.00 1.81  ? 139 SER A HA   139 SER A HA   1 
ATOM 2082 H HB2  . SER A 1 139 ? 54.735 16.608  2.573  1.00 1.81  ? 139 SER A HB2  139 SER A 1HB  1 
ATOM 2083 H HB3  . SER A 1 139 ? 52.999 16.593  2.840  1.00 1.81  ? 139 SER A HB3  139 SER A 2HB  1 
ATOM 2084 H HG   . SER A 1 139 ? 53.131 18.805  1.921  1.00 1.81  ? 139 SER A HG   139 SER A HG   1 
ATOM 2085 N N    . SER A 1 140 ? 56.391 18.251  4.363  1.00 2.45  ? 140 SER A N    140 SER A N    1 
ATOM 2086 C CA   . SER A 1 140 ? 57.786 18.896  4.447  1.00 2.45  ? 140 SER A CA   140 SER A CA   1 
ATOM 2087 C C    . SER A 1 140 ? 58.530 19.965  5.120  1.00 2.45  ? 140 SER A C    140 SER A C    1 
ATOM 2088 O O    . SER A 1 140 ? 59.480 20.472  4.346  1.00 2.45  ? 140 SER A O    140 SER A O    1 
ATOM 2089 C CB   . SER A 1 140 ? 58.120 19.283  3.019  1.00 2.45  ? 140 SER A CB   140 SER A CB   1 
ATOM 2090 O OG   . SER A 1 140 ? 57.936 18.200  2.149  1.00 2.45  ? 140 SER A OG   140 SER A OG   1 
ATOM 2091 H H    . SER A 1 140 ? 56.272 17.261  4.551  1.00 2.45  ? 140 SER A H    140 SER A H    1 
ATOM 2092 H HA   . SER A 1 140 ? 58.487 18.154  4.831  1.00 2.45  ? 140 SER A HA   140 SER A HA   1 
ATOM 2093 H HB2  . SER A 1 140 ? 57.486 20.113  2.710  1.00 2.45  ? 140 SER A HB2  140 SER A 1HB  1 
ATOM 2094 H HB3  . SER A 1 140 ? 59.153 19.623  2.968  1.00 2.45  ? 140 SER A HB3  140 SER A 2HB  1 
ATOM 2095 H HG   . SER A 1 140 ? 58.425 17.467  2.531  1.00 2.45  ? 140 SER A HG   140 SER A HG   1 
ATOM 2096 N N    . GLY A 1 141 ? 58.164 20.120  6.575  1.00 4.17  ? 141 GLY A N    141 GLY A N    1 
ATOM 2097 C CA   . GLY A 1 141 ? 58.919 21.050  7.456  1.00 4.17  ? 141 GLY A CA   141 GLY A CA   1 
ATOM 2098 C C    . GLY A 1 141 ? 59.480 19.580  7.948  1.00 4.17  ? 141 GLY A C    141 GLY A C    1 
ATOM 2099 O O    . GLY A 1 141 ? 59.737 18.625  6.964  1.00 4.17  ? 141 GLY A O    141 GLY A O    1 
ATOM 2100 H H    . GLY A 1 141 ? 57.387 19.555  6.940  1.00 4.17  ? 141 GLY A H    141 GLY A H    1 
ATOM 2101 H HA2  . GLY A 1 141 ? 59.500 21.740  6.844  1.00 4.17  ? 141 GLY A HA2  141 GLY A 1HA  1 
ATOM 2102 H HA3  . GLY A 1 141 ? 58.218 21.649  8.037  1.00 4.17  ? 141 GLY A HA3  141 GLY A 2HA  1 
ATOM 2103 N N    . SER A 1 142 ? 59.918 19.562  9.290  1.00 5.78  ? 142 SER A N    142 SER A N    1 
ATOM 2104 C CA   . SER A 1 142 ? 60.380 18.225  9.663  1.00 5.78  ? 142 SER A CA   142 SER A CA   1 
ATOM 2105 C C    . SER A 1 142 ? 60.032 18.280  11.208 1.00 5.78  ? 142 SER A C    142 SER A C    1 
ATOM 2106 O O    . SER A 1 142 ? 59.958 19.525  11.653 1.00 5.78  ? 142 SER A O    142 SER A O    1 
ATOM 2107 C CB   . SER A 1 142 ? 61.853 18.007  9.381  1.00 5.78  ? 142 SER A CB   142 SER A CB   1 
ATOM 2108 O OG   . SER A 1 142 ? 62.645 18.858  10.162 1.00 5.78  ? 142 SER A OG   142 SER A OG   1 
ATOM 2109 H H    . SER A 1 142 ? 59.782 20.322  9.941  1.00 5.78  ? 142 SER A H    142 SER A H    1 
ATOM 2110 H HA   . SER A 1 142 ? 59.823 17.491  9.077  1.00 5.78  ? 142 SER A HA   142 SER A HA   1 
ATOM 2111 H HB2  . SER A 1 142 ? 62.114 16.970  9.590  1.00 5.78  ? 142 SER A HB2  142 SER A 1HB  1 
ATOM 2112 H HB3  . SER A 1 142 ? 62.052 18.187  8.326  1.00 5.78  ? 142 SER A HB3  142 SER A 2HB  1 
ATOM 2113 H HG   . SER A 1 142 ? 63.428 18.353  10.394 1.00 5.78  ? 142 SER A HG   142 SER A HG   1 
ATOM 2114 N N    . GLY A 1 143 ? 59.849 17.035  12.061 1.00 8.57  ? 143 GLY A N    143 GLY A N    1 
ATOM 2115 C CA   . GLY A 1 143 ? 59.610 17.528  13.397 1.00 8.57  ? 143 GLY A CA   143 GLY A CA   1 
ATOM 2116 C C    . GLY A 1 143 ? 60.602 16.772  14.289 1.00 8.57  ? 143 GLY A C    143 GLY A C    1 
ATOM 2117 O O    . GLY A 1 143 ? 60.526 16.928  15.533 1.00 8.57  ? 143 GLY A O    143 GLY A O    1 
ATOM 2118 H H    . GLY A 1 143 ? 59.887 16.058  11.788 1.00 8.57  ? 143 GLY A H    143 GLY A H    1 
ATOM 2119 H HA2  . GLY A 1 143 ? 59.762 18.608  13.419 1.00 8.57  ? 143 GLY A HA2  143 GLY A 1HA  1 
ATOM 2120 H HA3  . GLY A 1 143 ? 58.572 17.344  13.672 1.00 8.57  ? 143 GLY A HA3  143 GLY A 2HA  1 
ATOM 2121 N N    . GLY A 1 144 ? 61.646 16.134  13.595 1.00 7.98  ? 144 GLY A N    144 GLY A N    1 
ATOM 2122 C CA   . GLY A 1 144 ? 62.672 15.261  14.156 1.00 7.98  ? 144 GLY A CA   144 GLY A CA   1 
ATOM 2123 C C    . GLY A 1 144 ? 62.467 14.305  13.012 1.00 7.98  ? 144 GLY A C    144 GLY A C    1 
ATOM 2124 O O    . GLY A 1 144 ? 61.401 14.628  12.339 1.00 7.98  ? 144 GLY A O    144 GLY A O    1 
ATOM 2125 H H    . GLY A 1 144 ? 61.642 16.202  12.581 1.00 7.98  ? 144 GLY A H    144 GLY A H    1 
ATOM 2126 H HA2  . GLY A 1 144 ? 63.611 15.808  14.238 1.00 7.98  ? 144 GLY A HA2  144 GLY A 1HA  1 
ATOM 2127 H HA3  . GLY A 1 144 ? 62.385 14.963  15.164 1.00 7.98  ? 144 GLY A HA3  144 GLY A 2HA  1 
ATOM 2128 N N    . GLY A 1 145 ? 63.417 13.224  12.749 1.00 6.80  ? 145 GLY A N    145 GLY A N    1 
ATOM 2129 C CA   . GLY A 1 145 ? 63.104 12.436  11.524 1.00 6.80  ? 145 GLY A CA   145 GLY A CA   1 
ATOM 2130 C C    . GLY A 1 145 ? 63.607 13.036  10.248 1.00 6.80  ? 145 GLY A C    145 GLY A C    1 
ATOM 2131 O O    . GLY A 1 145 ? 64.515 13.980  10.338 1.00 6.80  ? 145 GLY A O    145 GLY A O    1 
ATOM 2132 H H    . GLY A 1 145 ? 64.193 13.017  13.354 1.00 6.80  ? 145 GLY A H    145 GLY A H    1 
ATOM 2133 H HA2  . GLY A 1 145 ? 63.530 11.437  11.615 1.00 6.80  ? 145 GLY A HA2  145 GLY A 1HA  1 
ATOM 2134 H HA3  . GLY A 1 145 ? 62.024 12.317  11.434 1.00 6.80  ? 145 GLY A HA3  145 GLY A 2HA  1 
ATOM 2135 N N    . GLY A 1 146 ? 62.943 12.420  9.085  1.00 5.85  ? 146 GLY A N    146 GLY A N    1 
ATOM 2136 C CA   . GLY A 1 146 ? 63.284 12.772  7.660  1.00 5.85  ? 146 GLY A CA   146 GLY A CA   1 
ATOM 2137 C C    . GLY A 1 146 ? 62.186 13.876  7.553  1.00 5.85  ? 146 GLY A C    146 GLY A C    1 
ATOM 2138 O O    . GLY A 1 146 ? 61.776 14.369  8.756  1.00 5.85  ? 146 GLY A O    146 GLY A O    1 
ATOM 2139 H H    . GLY A 1 146 ? 62.145 11.700  9.178  1.00 5.85  ? 146 GLY A H    146 GLY A H    1 
ATOM 2140 H HA2  . GLY A 1 146 ? 64.327 13.085  7.602  1.00 5.85  ? 146 GLY A HA2  146 GLY A 1HA  1 
ATOM 2141 H HA3  . GLY A 1 146 ? 63.179 11.888  7.032  1.00 5.85  ? 146 GLY A HA3  146 GLY A 2HA  1 
ATOM 2142 N N    . SER A 1 147 ? 61.761 14.281  6.171  1.00 3.92  ? 147 SER A N    147 SER A N    1 
ATOM 2143 C CA   . SER A 1 147 ? 60.801 15.315  6.114  1.00 3.92  ? 147 SER A CA   147 SER A CA   1 
ATOM 2144 C C    . SER A 1 147 ? 59.341 14.851  6.691  1.00 3.92  ? 147 SER A C    147 SER A C    1 
ATOM 2145 O O    . SER A 1 147 ? 59.060 13.506  6.750  1.00 3.92  ? 147 SER A O    147 SER A O    1 
ATOM 2146 C CB   . SER A 1 147 ? 60.717 15.773  4.671  1.00 3.92  ? 147 SER A CB   147 SER A CB   1 
ATOM 2147 O OG   . SER A 1 147 ? 60.133 14.788  3.864  1.00 3.92  ? 147 SER A OG   147 SER A OG   1 
ATOM 2148 H H    . SER A 1 147 ? 62.132 13.879  5.320  1.00 3.92  ? 147 SER A H    147 SER A H    1 
ATOM 2149 H HA   . SER A 1 147 ? 61.138 16.135  6.749  1.00 3.92  ? 147 SER A HA   147 SER A HA   1 
ATOM 2150 H HB2  . SER A 1 147 ? 60.129 16.689  4.614  1.00 3.92  ? 147 SER A HB2  147 SER A 1HB  1 
ATOM 2151 H HB3  . SER A 1 147 ? 61.716 16.003  4.303  1.00 3.92  ? 147 SER A HB3  147 SER A 2HB  1 
ATOM 2152 H HG   . SER A 1 147 ? 59.186 14.861  4.000  1.00 3.92  ? 147 SER A HG   147 SER A HG   1 
ATOM 2153 N N    . ASP A 1 148 ? 58.419 16.057  6.984  1.00 3.94  ? 148 ASP A N    148 ASP A N    1 
ATOM 2154 C CA   . ASP A 1 148 ? 57.163 15.595  7.417  1.00 3.94  ? 148 ASP A CA   148 ASP A CA   1 
ATOM 2155 C C    . ASP A 1 148 ? 56.392 14.294  6.479  1.00 3.94  ? 148 ASP A C    148 ASP A C    1 
ATOM 2156 O O    . ASP A 1 148 ? 55.983 14.707  5.275  1.00 3.94  ? 148 ASP A O    148 ASP A O    1 
ATOM 2157 C CB   . ASP A 1 148 ? 56.313 16.866  7.478  1.00 3.94  ? 148 ASP A CB   148 ASP A CB   1 
ATOM 2158 C CG   . ASP A 1 148 ? 56.730 17.804  8.603  1.00 3.94  ? 148 ASP A CG   148 ASP A CG   1 
ATOM 2159 O OD1  . ASP A 1 148 ? 57.240 17.327  9.590  1.00 3.94  ? 148 ASP A OD1  148 ASP A OD1  1 
ATOM 2160 O OD2  . ASP A 1 148 ? 56.536 18.988  8.465  1.00 3.94  ? 148 ASP A OD2  148 ASP A OD2  1 
ATOM 2161 H H    . ASP A 1 148 ? 58.893 17.058  7.024  1.00 3.94  ? 148 ASP A H    148 ASP A H    1 
ATOM 2162 H HA   . ASP A 1 148 ? 57.283 15.138  8.400  1.00 3.94  ? 148 ASP A HA   148 ASP A HA   1 
ATOM 2163 H HB2  . ASP A 1 148 ? 56.389 17.401  6.532  1.00 3.94  ? 148 ASP A HB2  148 ASP A 1HB  1 
ATOM 2164 H HB3  . ASP A 1 148 ? 55.266 16.597  7.619  1.00 3.94  ? 148 ASP A HB3  148 ASP A 2HB  1 
ATOM 2165 N N    . ILE A 1 149 ? 56.349 12.644  6.934  1.00 4.43  ? 149 ILE A N    149 ILE A N    1 
ATOM 2166 C CA   . ILE A 1 149 ? 55.624 12.423  5.827  1.00 4.43  ? 149 ILE A CA   149 ILE A CA   1 
ATOM 2167 C C    . ILE A 1 149 ? 54.277 12.783  5.269  1.00 4.43  ? 149 ILE A C    149 ILE A C    1 
ATOM 2168 O O    . ILE A 1 149 ? 53.185 12.991  5.946  1.00 4.43  ? 149 ILE A O    149 ILE A O    1 
ATOM 2169 C CB   . ILE A 1 149 ? 55.688 10.885  5.791  1.00 4.43  ? 149 ILE A CB   149 ILE A CB   1 
ATOM 2170 C CG1  . ILE A 1 149 ? 57.137 10.414  5.638  1.00 4.43  ? 149 ILE A CG1  149 ILE A CG1  1 
ATOM 2171 C CG2  . ILE A 1 149 ? 54.828 10.343  4.660  1.00 4.43  ? 149 ILE A CG2  149 ILE A CG2  1 
ATOM 2172 C CD1  . ILE A 1 149 ? 57.875 11.070  4.493  1.00 4.43  ? 149 ILE A CD1  149 ILE A CD1  1 
ATOM 2173 H H    . ILE A 1 149 ? 57.382 12.952  7.220  1.00 4.43  ? 149 ILE A H    149 ILE A H    1 
ATOM 2174 H HA   . ILE A 1 149 ? 56.124 12.903  4.985  1.00 4.43  ? 149 ILE A HA   149 ILE A HA   1 
ATOM 2175 H HB   . ILE A 1 149 ? 55.325 10.484  6.736  1.00 4.43  ? 149 ILE A HB   149 ILE A HB   1 
ATOM 2176 H HG12 . ILE A 1 149 ? 57.684 10.618  6.558  1.00 4.43  ? 149 ILE A HG12 149 ILE A 1HG1 1 
ATOM 2177 H HG13 . ILE A 1 149 ? 57.155 9.336   5.480  1.00 4.43  ? 149 ILE A HG13 149 ILE A 2HG1 1 
ATOM 2178 H HG21 . ILE A 1 149 ? 54.885 9.255   4.648  1.00 4.43  ? 149 ILE A HG21 149 ILE A 1HG2 1 
ATOM 2179 H HG22 . ILE A 1 149 ? 53.794 10.651  4.811  1.00 4.43  ? 149 ILE A HG22 149 ILE A 2HG2 1 
ATOM 2180 H HG23 . ILE A 1 149 ? 55.187 10.736  3.708  1.00 4.43  ? 149 ILE A HG23 149 ILE A 3HG2 1 
ATOM 2181 H HD11 . ILE A 1 149 ? 58.894 10.686  4.449  1.00 4.43  ? 149 ILE A HD11 149 ILE A 1HD1 1 
ATOM 2182 H HD12 . ILE A 1 149 ? 57.363 10.849  3.556  1.00 4.43  ? 149 ILE A HD12 149 ILE A 2HD1 1 
ATOM 2183 H HD13 . ILE A 1 149 ? 57.901 12.148  4.648  1.00 4.43  ? 149 ILE A HD13 149 ILE A 3HD1 1 
ATOM 2184 N N    . GLN A 1 150 ? 54.700 13.020  3.775  1.00 4.99  ? 150 GLN A N    150 GLN A N    1 
ATOM 2185 C CA   . GLN A 1 150 ? 53.854 13.259  2.503  1.00 4.99  ? 150 GLN A CA   150 GLN A CA   1 
ATOM 2186 C C    . GLN A 1 150 ? 53.119 12.010  1.943  1.00 4.99  ? 150 GLN A C    150 GLN A C    1 
ATOM 2187 O O    . GLN A 1 150 ? 53.856 11.149  1.243  1.00 4.99  ? 150 GLN A O    150 GLN A O    1 
ATOM 2188 C CB   . GLN A 1 150 ? 54.731 13.830  1.385  1.00 4.99  ? 150 GLN A CB   150 GLN A CB   1 
ATOM 2189 C CG   . GLN A 1 150 ? 53.960 14.264  0.150  1.00 4.99  ? 150 GLN A CG   150 GLN A CG   1 
ATOM 2190 C CD   . GLN A 1 150 ? 54.847 14.941  -0.877 1.00 4.99  ? 150 GLN A CD   150 GLN A CD   1 
ATOM 2191 O OE1  . GLN A 1 150 ? 55.693 15.773  -0.536 1.00 4.99  ? 150 GLN A OE1  150 GLN A OE1  1 
ATOM 2192 N NE2  . GLN A 1 150 ? 54.659 14.589  -2.144 1.00 4.99  ? 150 GLN A NE2  150 GLN A NE2  1 
ATOM 2193 H H    . GLN A 1 150 ? 55.494 13.568  4.051  1.00 4.99  ? 150 GLN A H    150 GLN A H    1 
ATOM 2194 H HA   . GLN A 1 150 ? 53.072 13.980  2.738  1.00 4.99  ? 150 GLN A HA   150 GLN A HA   1 
ATOM 2195 H HB2  . GLN A 1 150 ? 55.282 14.693  1.759  1.00 4.99  ? 150 GLN A HB2  150 GLN A 1HB  1 
ATOM 2196 H HB3  . GLN A 1 150 ? 55.463 13.082  1.079  1.00 4.99  ? 150 GLN A HB3  150 GLN A 2HB  1 
ATOM 2197 H HG2  . GLN A 1 150 ? 53.510 13.386  -0.313 1.00 4.99  ? 150 GLN A HG2  150 GLN A 1HG  1 
ATOM 2198 H HG3  . GLN A 1 150 ? 53.183 14.969  0.448  1.00 4.99  ? 150 GLN A HG3  150 GLN A 2HG  1 
ATOM 2199 H HE21 . GLN A 1 150 ? 55.215 15.003  -2.867 1.00 4.99  ? 150 GLN A HE21 150 GLN A 1HE2 1 
ATOM 2200 H HE22 . GLN A 1 150 ? 53.962 13.911  -2.377 1.00 4.99  ? 150 GLN A HE22 150 GLN A 2HE2 1 
ATOM 2201 N N    . LEU A 1 151 ? 51.556 11.998  2.250  1.00 5.50  ? 151 LEU A N    151 LEU A N    1 
ATOM 2202 C CA   . LEU A 1 151 ? 50.931 10.826  1.713  1.00 5.50  ? 151 LEU A CA   151 LEU A CA   1 
ATOM 2203 C C    . LEU A 1 151 ? 50.060 11.395  0.426  1.00 5.50  ? 151 LEU A C    151 LEU A C    1 
ATOM 2204 O O    . LEU A 1 151 ? 49.125 12.053  0.516  1.00 5.50  ? 151 LEU A O    151 LEU A O    1 
ATOM 2205 C CB   . LEU A 1 151 ? 50.065 10.146  2.780  1.00 5.50  ? 151 LEU A CB   151 LEU A CB   1 
ATOM 2206 C CG   . LEU A 1 151 ? 50.793 9.740   4.068  1.00 5.50  ? 151 LEU A CG   151 LEU A CG   1 
ATOM 2207 C CD1  . LEU A 1 151 ? 49.807 9.084   5.025  1.00 5.50  ? 151 LEU A CD1  151 LEU A CD1  1 
ATOM 2208 C CD2  . LEU A 1 151 ? 51.936 8.795   3.729  1.00 5.50  ? 151 LEU A CD2  151 LEU A CD2  1 
ATOM 2209 H H    . LEU A 1 151 ? 51.101 12.783  2.663  1.00 5.50  ? 151 LEU A H    151 LEU A H    1 
ATOM 2210 H HA   . LEU A 1 151 ? 51.710 10.131  1.400  1.00 5.50  ? 151 LEU A HA   151 LEU A HA   1 
ATOM 2211 H HB2  . LEU A 1 151 ? 49.258 10.823  3.056  1.00 5.50  ? 151 LEU A HB2  151 LEU A 1HB  1 
ATOM 2212 H HB3  . LEU A 1 151 ? 49.626 9.246   2.350  1.00 5.50  ? 151 LEU A HB3  151 LEU A 2HB  1 
ATOM 2213 H HG   . LEU A 1 151 ? 51.191 10.629  4.557  1.00 5.50  ? 151 LEU A HG   151 LEU A HG   1 
ATOM 2214 H HD11 . LEU A 1 151 ? 50.324 8.796   5.940  1.00 5.50  ? 151 LEU A HD11 151 LEU A 1HD1 1 
ATOM 2215 H HD12 . LEU A 1 151 ? 49.011 9.789   5.266  1.00 5.50  ? 151 LEU A HD12 151 LEU A 2HD1 1 
ATOM 2216 H HD13 . LEU A 1 151 ? 49.379 8.199   4.556  1.00 5.50  ? 151 LEU A HD13 151 LEU A 3HD1 1 
ATOM 2217 H HD21 . LEU A 1 151 ? 52.454 8.507   4.644  1.00 5.50  ? 151 LEU A HD21 151 LEU A 1HD2 1 
ATOM 2218 H HD22 . LEU A 1 151 ? 51.539 7.904   3.241  1.00 5.50  ? 151 LEU A HD22 151 LEU A 2HD2 1 
ATOM 2219 H HD23 . LEU A 1 151 ? 52.635 9.295   3.058  1.00 5.50  ? 151 LEU A HD23 151 LEU A 3HD2 1 
ATOM 2220 N N    . THR A 1 152 ? 49.941 10.781  -0.585 1.00 5.60  ? 152 THR A N    152 THR A N    1 
ATOM 2221 C CA   . THR A 1 152 ? 49.431 11.058  -1.855 1.00 5.60  ? 152 THR A CA   152 THR A CA   1 
ATOM 2222 C C    . THR A 1 152 ? 48.191 9.672   -2.146 1.00 5.60  ? 152 THR A C    152 THR A C    1 
ATOM 2223 O O    . THR A 1 152 ? 48.133 8.483   -1.495 1.00 5.60  ? 152 THR A O    152 THR A O    1 
ATOM 2224 C CB   . THR A 1 152 ? 50.608 11.134  -2.845 1.00 5.60  ? 152 THR A CB   152 THR A CB   1 
ATOM 2225 O OG1  . THR A 1 152 ? 51.196 9.835   -2.993 1.00 5.60  ? 152 THR A OG1  152 THR A OG1  1 
ATOM 2226 C CG2  . THR A 1 152 ? 51.662 12.110  -2.346 1.00 5.60  ? 152 THR A CG2  152 THR A CG2  1 
ATOM 2227 H H    . THR A 1 152 ? 50.437 10.026  -0.606 1.00 5.60  ? 152 THR A H    152 THR A H    1 
ATOM 2228 H HA   . THR A 1 152 ? 48.918 12.020  -1.820 1.00 5.60  ? 152 THR A HA   152 THR A HA   1 
ATOM 2229 H HB   . THR A 1 152 ? 50.245 11.466  -3.818 1.00 5.60  ? 152 THR A HB   152 THR A HB   1 
ATOM 2230 H HG1  . THR A 1 152 ? 50.903 9.268   -2.275 1.00 5.60  ? 152 THR A HG1  152 THR A HG1  1 
ATOM 2231 H HG21 . THR A 1 152 ? 52.486 12.151  -3.058 1.00 5.60  ? 152 THR A HG21 152 THR A 1HG2 1 
ATOM 2232 H HG22 . THR A 1 152 ? 51.221 13.101  -2.243 1.00 5.60  ? 152 THR A HG22 152 THR A 2HG2 1 
ATOM 2233 H HG23 . THR A 1 152 ? 52.036 11.778  -1.378 1.00 5.60  ? 152 THR A HG23 152 THR A 3HG2 1 
ATOM 2234 N N    . GLN A 1 153 ? 48.182 8.934   -3.200 1.00 5.92  ? 153 GLN A N    153 GLN A N    1 
ATOM 2235 C CA   . GLN A 1 153 ? 46.758 8.786   -3.501 1.00 5.92  ? 153 GLN A CA   153 GLN A CA   1 
ATOM 2236 C C    . GLN A 1 153 ? 46.079 7.429   -3.236 1.00 5.92  ? 153 GLN A C    153 GLN A C    1 
ATOM 2237 O O    . GLN A 1 153 ? 46.769 6.313   -3.569 1.00 5.92  ? 153 GLN A O    153 GLN A O    1 
ATOM 2238 C CB   . GLN A 1 153 ? 46.545 9.148   -4.973 1.00 5.92  ? 153 GLN A CB   153 GLN A CB   1 
ATOM 2239 C CG   . GLN A 1 153 ? 46.902 10.583  -5.319 1.00 5.92  ? 153 GLN A CG   153 GLN A CG   1 
ATOM 2240 C CD   . GLN A 1 153 ? 46.014 11.588  -4.611 1.00 5.92  ? 153 GLN A CD   153 GLN A CD   1 
ATOM 2241 O OE1  . GLN A 1 153 ? 46.498 12.476  -3.903 1.00 5.92  ? 153 GLN A OE1  153 GLN A OE1  1 
ATOM 2242 N NE2  . GLN A 1 153 ? 44.706 11.455  -4.797 1.00 5.92  ? 153 GLN A NE2  153 GLN A NE2  1 
ATOM 2243 H H    . GLN A 1 153 ? 48.807 9.156   -3.951 1.00 5.92  ? 153 GLN A H    153 GLN A H    1 
ATOM 2244 H HA   . GLN A 1 153 ? 46.197 9.472   -2.867 1.00 5.92  ? 153 GLN A HA   153 GLN A HA   1 
ATOM 2245 H HB2  . GLN A 1 153 ? 47.146 8.491   -5.601 1.00 5.92  ? 153 GLN A HB2  153 GLN A 1HB  1 
ATOM 2246 H HB3  . GLN A 1 153 ? 45.500 8.988   -5.239 1.00 5.92  ? 153 GLN A HB3  153 GLN A 2HB  1 
ATOM 2247 H HG2  . GLN A 1 153 ? 47.935 10.771  -5.023 1.00 5.92  ? 153 GLN A HG2  153 GLN A 1HG  1 
ATOM 2248 H HG3  . GLN A 1 153 ? 46.790 10.726  -6.394 1.00 5.92  ? 153 GLN A HG3  153 GLN A 2HG  1 
ATOM 2249 H HE21 . GLN A 1 153 ? 44.070 12.089  -4.355 1.00 5.92  ? 153 GLN A HE21 153 GLN A 1HE2 1 
ATOM 2250 H HE22 . GLN A 1 153 ? 44.355 10.721  -5.379 1.00 5.92  ? 153 GLN A HE22 153 GLN A 2HE2 1 
ATOM 2251 N N    . SER A 1 154 ? 44.531 7.639   -2.970 1.00 5.79  ? 154 SER A N    154 SER A N    1 
ATOM 2252 C CA   . SER A 1 154 ? 43.766 6.397   -2.919 1.00 5.79  ? 154 SER A CA   154 SER A CA   1 
ATOM 2253 C C    . SER A 1 154 ? 42.941 6.860   -3.988 1.00 5.79  ? 154 SER A C    154 SER A C    1 
ATOM 2254 O O    . SER A 1 154 ? 42.538 8.111   -3.785 1.00 5.79  ? 154 SER A O    154 SER A O    1 
ATOM 2255 C CB   . SER A 1 154 ? 43.011 6.117   -1.634 1.00 5.79  ? 154 SER A CB   154 SER A CB   1 
ATOM 2256 O OG   . SER A 1 154 ? 42.027 7.089   -1.408 1.00 5.79  ? 154 SER A OG   154 SER A OG   1 
ATOM 2257 H H    . SER A 1 154 ? 44.144 8.543   -2.737 1.00 5.79  ? 154 SER A H    154 SER A H    1 
ATOM 2258 H HA   . SER A 1 154 ? 44.455 5.561   -3.043 1.00 5.79  ? 154 SER A HA   154 SER A HA   1 
ATOM 2259 H HB2  . SER A 1 154 ? 42.547 5.133   -1.691 1.00 5.79  ? 154 SER A HB2  154 SER A 1HB  1 
ATOM 2260 H HB3  . SER A 1 154 ? 43.710 6.102   -0.798 1.00 5.79  ? 154 SER A HB3  154 SER A 2HB  1 
ATOM 2261 H HG   . SER A 1 154 ? 41.189 6.621   -1.406 1.00 5.79  ? 154 SER A HG   154 SER A HG   1 
ATOM 2262 N N    . PRO A 1 155 ? 42.340 5.729   -4.836 1.00 6.27  ? 155 PRO A N    155 PRO A N    1 
ATOM 2263 C CA   . PRO A 1 155 ? 41.331 5.852   -5.870 1.00 6.27  ? 155 PRO A CA   155 PRO A CA   1 
ATOM 2264 C C    . PRO A 1 155 ? 40.047 6.276   -5.268 1.00 6.27  ? 155 PRO A C    155 PRO A C    1 
ATOM 2265 O O    . PRO A 1 155 ? 39.225 5.672   -6.023 1.00 6.27  ? 155 PRO A O    155 PRO A O    1 
ATOM 2266 C CB   . PRO A 1 155 ? 41.237 4.442   -6.461 1.00 6.27  ? 155 PRO A CB   155 PRO A CB   1 
ATOM 2267 C CG   . PRO A 1 155 ? 42.607 3.881   -6.288 1.00 6.27  ? 155 PRO A CG   155 PRO A CG   1 
ATOM 2268 C CD   . PRO A 1 155 ? 43.075 4.434   -4.968 1.00 6.27  ? 155 PRO A CD   155 PRO A CD   1 
ATOM 2269 H HA   . PRO A 1 155 ? 41.678 6.568   -6.630 1.00 6.27  ? 155 PRO A HA   155 PRO A HA   1 
ATOM 2270 H HB2  . PRO A 1 155 ? 40.468 3.862   -5.929 1.00 6.27  ? 155 PRO A HB2  155 PRO A 1HB  1 
ATOM 2271 H HB3  . PRO A 1 155 ? 40.927 4.495   -7.515 1.00 6.27  ? 155 PRO A HB3  155 PRO A 2HB  1 
ATOM 2272 H HG2  . PRO A 1 155 ? 42.572 2.782   -6.297 1.00 6.27  ? 155 PRO A HG2  155 PRO A 1HG  1 
ATOM 2273 H HG3  . PRO A 1 155 ? 43.251 4.185   -7.127 1.00 6.27  ? 155 PRO A HG3  155 PRO A 2HG  1 
ATOM 2274 H HD2  . PRO A 1 155 ? 42.803 3.738   -4.161 1.00 6.27  ? 155 PRO A HD2  155 PRO A 1HD  1 
ATOM 2275 H HD3  . PRO A 1 155 ? 44.164 4.587   -4.999 1.00 6.27  ? 155 PRO A HD3  155 PRO A 2HD  1 
ATOM 2276 N N    . ASP A 1 156 ? 39.897 7.204   -3.977 1.00 6.19  ? 156 ASP A N    156 ASP A N    1 
ATOM 2277 C CA   . ASP A 1 156 ? 38.557 7.504   -3.726 1.00 6.19  ? 156 ASP A CA   156 ASP A CA   1 
ATOM 2278 C C    . ASP A 1 156 ? 37.570 6.297   -3.575 1.00 6.19  ? 156 ASP A C    156 ASP A C    1 
ATOM 2279 O O    . ASP A 1 156 ? 38.170 5.108   -3.393 1.00 6.19  ? 156 ASP A O    156 ASP A O    1 
ATOM 2280 C CB   . ASP A 1 156 ? 38.087 8.426   -4.854 1.00 6.19  ? 156 ASP A CB   156 ASP A CB   1 
ATOM 2281 C CG   . ASP A 1 156 ? 38.879 9.725   -4.925 1.00 6.19  ? 156 ASP A CG   156 ASP A CG   1 
ATOM 2282 O OD1  . ASP A 1 156 ? 39.656 9.974   -4.033 1.00 6.19  ? 156 ASP A OD1  156 ASP A OD1  1 
ATOM 2283 O OD2  . ASP A 1 156 ? 38.700 10.456  -5.869 1.00 6.19  ? 156 ASP A OD2  156 ASP A OD2  1 
ATOM 2284 H H    . ASP A 1 156 ? 40.678 7.708   -3.863 1.00 6.19  ? 156 ASP A H    156 ASP A H    1 
ATOM 2285 H HA   . ASP A 1 156 ? 38.490 8.015   -2.766 1.00 6.19  ? 156 ASP A HA   156 ASP A HA   1 
ATOM 2286 H HB2  . ASP A 1 156 ? 38.179 7.909   -5.809 1.00 6.19  ? 156 ASP A HB2  156 ASP A 1HB  1 
ATOM 2287 H HB3  . ASP A 1 156 ? 37.033 8.668   -4.712 1.00 6.19  ? 156 ASP A HB3  156 ASP A 2HB  1 
ATOM 2288 N N    . SER A 1 157 ? 36.028 6.526   -3.915 1.00 6.28  ? 157 SER A N    157 SER A N    1 
ATOM 2289 C CA   . SER A 1 157 ? 35.310 5.449   -3.379 1.00 6.28  ? 157 SER A CA   157 SER A CA   1 
ATOM 2290 C C    . SER A 1 157 ? 35.396 4.165   -4.192 1.00 6.28  ? 157 SER A C    157 SER A C    1 
ATOM 2291 O O    . SER A 1 157 ? 35.818 4.323   -5.451 1.00 6.28  ? 157 SER A O    157 SER A O    1 
ATOM 2292 C CB   . SER A 1 157 ? 33.862 5.870   -3.229 1.00 6.28  ? 157 SER A CB   157 SER A CB   1 
ATOM 2293 O OG   . SER A 1 157 ? 33.292 6.162   -4.476 1.00 6.28  ? 157 SER A OG   157 SER A OG   1 
ATOM 2294 H H    . SER A 1 157 ? 35.402 7.426   -3.623 1.00 6.28  ? 157 SER A H    157 SER A H    1 
ATOM 2295 H HA   . SER A 1 157 ? 35.727 5.209   -2.399 1.00 6.28  ? 157 SER A HA   157 SER A HA   1 
ATOM 2296 H HB2  . SER A 1 157 ? 33.298 5.072   -2.747 1.00 6.28  ? 157 SER A HB2  157 SER A 1HB  1 
ATOM 2297 H HB3  . SER A 1 157 ? 33.802 6.747   -2.586 1.00 6.28  ? 157 SER A HB3  157 SER A 2HB  1 
ATOM 2298 H HG   . SER A 1 157 ? 33.305 7.119   -4.556 1.00 6.28  ? 157 SER A HG   157 SER A HG   1 
ATOM 2299 N N    . LEU A 1 158 ? 35.077 2.907   -3.385 1.00 6.24  ? 158 LEU A N    158 LEU A N    1 
ATOM 2300 C CA   . LEU A 1 158 ? 35.049 1.667   -4.164 1.00 6.24  ? 158 LEU A CA   158 LEU A CA   1 
ATOM 2301 C C    . LEU A 1 158 ? 33.879 0.802   -3.554 1.00 6.24  ? 158 LEU A C    158 LEU A C    1 
ATOM 2302 O O    . LEU A 1 158 ? 34.082 0.170   -2.327 1.00 6.24  ? 158 LEU A O    158 LEU A O    1 
ATOM 2303 C CB   . LEU A 1 158 ? 36.395 0.935   -4.084 1.00 6.24  ? 158 LEU A CB   158 LEU A CB   1 
ATOM 2304 C CG   . LEU A 1 158 ? 36.472 -0.400  -4.837 1.00 6.24  ? 158 LEU A CG   158 LEU A CG   1 
ATOM 2305 C CD1  . LEU A 1 158 ? 36.276 -0.154  -6.327 1.00 6.24  ? 158 LEU A CD1  158 LEU A CD1  1 
ATOM 2306 C CD2  . LEU A 1 158 ? 37.815 -1.060  -4.563 1.00 6.24  ? 158 LEU A CD2  158 LEU A CD2  1 
ATOM 2307 H H    . LEU A 1 158 ? 34.607 3.133   -2.531 1.00 6.24  ? 158 LEU A H    158 LEU A H    1 
ATOM 2308 H HA   . LEU A 1 158 ? 34.857 1.917   -5.206 1.00 6.24  ? 158 LEU A HA   158 LEU A HA   1 
ATOM 2309 H HB2  . LEU A 1 158 ? 37.169 1.586   -4.485 1.00 6.24  ? 158 LEU A HB2  158 LEU A 1HB  1 
ATOM 2310 H HB3  . LEU A 1 158 ? 36.622 0.737   -3.036 1.00 6.24  ? 158 LEU A HB3  158 LEU A 2HB  1 
ATOM 2311 H HG   . LEU A 1 158 ? 35.669 -1.055  -4.498 1.00 6.24  ? 158 LEU A HG   158 LEU A HG   1 
ATOM 2312 H HD11 . LEU A 1 158 ? 36.330 -1.102  -6.862 1.00 6.24  ? 158 LEU A HD11 158 LEU A 1HD1 1 
ATOM 2313 H HD12 . LEU A 1 158 ? 35.300 0.301   -6.495 1.00 6.24  ? 158 LEU A HD12 158 LEU A 2HD1 1 
ATOM 2314 H HD13 . LEU A 1 158 ? 37.056 0.513   -6.691 1.00 6.24  ? 158 LEU A HD13 158 LEU A 3HD1 1 
ATOM 2315 H HD21 . LEU A 1 158 ? 37.869 -2.009  -5.098 1.00 6.24  ? 158 LEU A HD21 158 LEU A 1HD2 1 
ATOM 2316 H HD22 . LEU A 1 158 ? 38.618 -0.406  -4.903 1.00 6.24  ? 158 LEU A HD22 158 LEU A 2HD2 1 
ATOM 2317 H HD23 . LEU A 1 158 ? 37.921 -1.240  -3.494 1.00 6.24  ? 158 LEU A HD23 158 LEU A 3HD2 1 
ATOM 2318 N N    . ALA A 1 159 ? 32.592 1.007   -4.328 1.00 6.50  ? 159 ALA A N    159 ALA A N    1 
ATOM 2319 C CA   . ALA A 1 159 ? 31.510 0.128   -3.922 1.00 6.50  ? 159 ALA A CA   159 ALA A CA   1 
ATOM 2320 C C    . ALA A 1 159 ? 32.032 -1.281  -4.397 1.00 6.50  ? 159 ALA A C    159 ALA A C    1 
ATOM 2321 O O    . ALA A 1 159 ? 32.659 -1.400  -5.631 1.00 6.50  ? 159 ALA A O    159 ALA A O    1 
ATOM 2322 C CB   . ALA A 1 159 ? 30.181 0.521   -4.550 1.00 6.50  ? 159 ALA A CB   159 ALA A CB   1 
ATOM 2323 H H    . ALA A 1 159 ? 32.519 1.588   -5.140 1.00 6.50  ? 159 ALA A H    159 ALA A H    1 
ATOM 2324 H HA   . ALA A 1 159 ? 31.404 0.199   -2.839 1.00 6.50  ? 159 ALA A HA   159 ALA A HA   1 
ATOM 2325 H HB1  . ALA A 1 159 ? 29.415 -0.198  -4.261 1.00 6.50  ? 159 ALA A HB1  159 ALA A 1HB  1 
ATOM 2326 H HB2  . ALA A 1 159 ? 29.895 1.515   -4.205 1.00 6.50  ? 159 ALA A HB2  159 ALA A 2HB  1 
ATOM 2327 H HB3  . ALA A 1 159 ? 30.280 0.529   -5.635 1.00 6.50  ? 159 ALA A HB3  159 ALA A 3HB  1 
ATOM 2328 N N    . VAL A 1 160 ? 31.756 -2.293  -3.342 1.00 6.21  ? 160 VAL A N    160 VAL A N    1 
ATOM 2329 C CA   . VAL A 1 160 ? 32.132 -3.679  -3.659 1.00 6.21  ? 160 VAL A CA   160 VAL A CA   1 
ATOM 2330 C C    . VAL A 1 160 ? 30.901 -4.577  -3.247 1.00 6.21  ? 160 VAL A C    160 VAL A C    1 
ATOM 2331 O O    . VAL A 1 160 ? 29.987 -4.158  -2.223 1.00 6.21  ? 160 VAL A O    160 VAL A O    1 
ATOM 2332 C CB   . VAL A 1 160 ? 33.404 -4.098  -2.897 1.00 6.21  ? 160 VAL A CB   160 VAL A CB   1 
ATOM 2333 C CG1  . VAL A 1 160 ? 33.805 -5.517  -3.272 1.00 6.21  ? 160 VAL A CG1  160 VAL A CG1  1 
ATOM 2334 C CG2  . VAL A 1 160 ? 34.531 -3.122  -3.195 1.00 6.21  ? 160 VAL A CG2  160 VAL A CG2  1 
ATOM 2335 H H    . VAL A 1 160 ? 31.327 -2.048  -2.459 1.00 6.21  ? 160 VAL A H    160 VAL A H    1 
ATOM 2336 H HA   . VAL A 1 160 ? 32.336 -3.747  -4.729 1.00 6.21  ? 160 VAL A HA   160 VAL A HA   1 
ATOM 2337 H HB   . VAL A 1 160 ? 33.192 -4.096  -1.828 1.00 6.21  ? 160 VAL A HB   160 VAL A HB   1 
ATOM 2338 H HG11 . VAL A 1 160 ? 34.706 -5.797  -2.724 1.00 6.21  ? 160 VAL A HG11 160 VAL A 1HG1 1 
ATOM 2339 H HG12 . VAL A 1 160 ? 32.998 -6.203  -3.016 1.00 6.21  ? 160 VAL A HG12 160 VAL A 2HG1 1 
ATOM 2340 H HG13 . VAL A 1 160 ? 34.003 -5.569  -4.342 1.00 6.21  ? 160 VAL A HG13 160 VAL A 3HG1 1 
ATOM 2341 H HG21 . VAL A 1 160 ? 35.427 -3.424  -2.653 1.00 6.21  ? 160 VAL A HG21 160 VAL A 1HG2 1 
ATOM 2342 H HG22 . VAL A 1 160 ? 34.738 -3.121  -4.265 1.00 6.21  ? 160 VAL A HG22 160 VAL A 2HG2 1 
ATOM 2343 H HG23 . VAL A 1 160 ? 34.237 -2.120  -2.881 1.00 6.21  ? 160 VAL A HG23 160 VAL A 3HG2 1 
ATOM 2344 N N    . SER A 1 161 ? 30.688 -5.588  -4.327 1.00 6.21  ? 161 SER A N    161 SER A N    1 
ATOM 2345 C CA   . SER A 1 161 ? 29.510 -6.525  -3.825 1.00 6.21  ? 161 SER A CA   161 SER A CA   1 
ATOM 2346 C C    . SER A 1 161 ? 30.078 -7.605  -2.945 1.00 6.21  ? 161 SER A C    161 SER A C    1 
ATOM 2347 O O    . SER A 1 161 ? 31.364 -7.887  -3.243 1.00 6.21  ? 161 SER A O    161 SER A O    1 
ATOM 2348 C CB   . SER A 1 161 ? 28.761 -7.186  -4.966 1.00 6.21  ? 161 SER A CB   161 SER A CB   1 
ATOM 2349 O OG   . SER A 1 161 ? 27.852 -8.138  -4.486 1.00 6.21  ? 161 SER A OG   161 SER A OG   1 
ATOM 2350 H H    . SER A 1 161 ? 31.319 -5.772  -5.107 1.00 6.21  ? 161 SER A H    161 SER A H    1 
ATOM 2351 H HA   . SER A 1 161 ? 28.794 -5.914  -3.273 1.00 6.21  ? 161 SER A HA   161 SER A HA   1 
ATOM 2352 H HB2  . SER A 1 161 ? 28.229 -6.428  -5.540 1.00 6.21  ? 161 SER A HB2  161 SER A 1HB  1 
ATOM 2353 H HB3  . SER A 1 161 ? 29.472 -7.665  -5.638 1.00 6.21  ? 161 SER A HB3  161 SER A 2HB  1 
ATOM 2354 H HG   . SER A 1 161 ? 28.383 -8.853  -4.128 1.00 6.21  ? 161 SER A HG   161 SER A HG   1 
ATOM 2355 N N    . LEU A 1 162 ? 29.113 -8.101  -1.918 1.00 6.14  ? 162 LEU A N    162 LEU A N    1 
ATOM 2356 C CA   . LEU A 1 162 ? 29.569 -9.279  -1.103 1.00 6.14  ? 162 LEU A CA   162 LEU A CA   1 
ATOM 2357 C C    . LEU A 1 162 ? 29.919 -10.326 -2.234 1.00 6.14  ? 162 LEU A C    162 LEU A C    1 
ATOM 2358 O O    . LEU A 1 162 ? 29.168 -10.310 -3.406 1.00 6.14  ? 162 LEU A O    162 LEU A O    1 
ATOM 2359 C CB   . LEU A 1 162 ? 28.484 -9.796  -0.149 1.00 6.14  ? 162 LEU A CB   162 LEU A CB   1 
ATOM 2360 C CG   . LEU A 1 162 ? 28.463 -9.156  1.245  1.00 6.14  ? 162 LEU A CG   162 LEU A CG   1 
ATOM 2361 C CD1  . LEU A 1 162 ? 28.199 -7.662  1.114  1.00 6.14  ? 162 LEU A CD1  162 LEU A CD1  1 
ATOM 2362 C CD2  . LEU A 1 162 ? 27.396 -9.828  2.096  1.00 6.14  ? 162 LEU A CD2  162 LEU A CD2  1 
ATOM 2363 H H    . LEU A 1 162 ? 28.185 -7.715  -1.823 1.00 6.14  ? 162 LEU A H    162 LEU A H    1 
ATOM 2364 H HA   . LEU A 1 162 ? 30.419 -8.972  -0.496 1.00 6.14  ? 162 LEU A HA   162 LEU A HA   1 
ATOM 2365 H HB2  . LEU A 1 162 ? 27.510 -9.627  -0.606 1.00 6.14  ? 162 LEU A HB2  162 LEU A 1HB  1 
ATOM 2366 H HB3  . LEU A 1 162 ? 28.619 -10.870 -0.019 1.00 6.14  ? 162 LEU A HB3  162 LEU A 2HB  1 
ATOM 2367 H HG   . LEU A 1 162 ? 29.437 -9.282  1.718  1.00 6.14  ? 162 LEU A HG   162 LEU A HG   1 
ATOM 2368 H HD11 . LEU A 1 162 ? 28.184 -7.208  2.105  1.00 6.14  ? 162 LEU A HD11 162 LEU A 1HD1 1 
ATOM 2369 H HD12 . LEU A 1 162 ? 28.987 -7.204  0.517  1.00 6.14  ? 162 LEU A HD12 162 LEU A 2HD1 1 
ATOM 2370 H HD13 . LEU A 1 162 ? 27.237 -7.504  0.628  1.00 6.14  ? 162 LEU A HD13 162 LEU A 3HD1 1 
ATOM 2371 H HD21 . LEU A 1 162 ? 27.382 -9.374  3.087  1.00 6.14  ? 162 LEU A HD21 162 LEU A 1HD2 1 
ATOM 2372 H HD22 . LEU A 1 162 ? 26.421 -9.701  1.625  1.00 6.14  ? 162 LEU A HD22 162 LEU A 2HD2 1 
ATOM 2373 H HD23 . LEU A 1 162 ? 27.619 -10.891 2.188  1.00 6.14  ? 162 LEU A HD23 162 LEU A 3HD2 1 
ATOM 2374 N N    . GLY A 1 163 ? 31.185 -11.134 -1.928 1.00 6.09  ? 163 GLY A N    163 GLY A N    1 
ATOM 2375 C CA   . GLY A 1 163 ? 31.864 -12.125 -2.399 1.00 6.09  ? 163 GLY A CA   163 GLY A CA   1 
ATOM 2376 C C    . GLY A 1 163 ? 32.902 -11.686 -3.403 1.00 6.09  ? 163 GLY A C    163 GLY A C    1 
ATOM 2377 O O    . GLY A 1 163 ? 33.744 -12.674 -3.788 1.00 6.09  ? 163 GLY A O    163 GLY A O    1 
ATOM 2378 H H    . GLY A 1 163 ? 30.801 -11.382 -2.838 1.00 6.09  ? 163 GLY A H    163 GLY A H    1 
ATOM 2379 H HA2  . GLY A 1 163 ? 32.359 -12.648 -1.581 1.00 6.09  ? 163 GLY A HA2  163 GLY A 1HA  1 
ATOM 2380 H HA3  . GLY A 1 163 ? 31.188 -12.836 -2.873 1.00 6.09  ? 163 GLY A HA3  163 GLY A 2HA  1 
ATOM 2381 N N    . GLU A 1 164 ? 32.826 -10.199 -3.788 1.00 6.00  ? 164 GLU A N    164 GLU A N    1 
ATOM 2382 C CA   . GLU A 1 164 ? 33.772 -9.804  -4.831 1.00 6.00  ? 164 GLU A CA   164 GLU A CA   1 
ATOM 2383 C C    . GLU A 1 164 ? 35.211 -9.527  -4.186 1.00 6.00  ? 164 GLU A C    164 GLU A C    1 
ATOM 2384 O O    . GLU A 1 164 ? 35.273 -9.202  -2.828 1.00 6.00  ? 164 GLU A O    164 GLU A O    1 
ATOM 2385 C CB   . GLU A 1 164 ? 33.248 -8.566  -5.563 1.00 6.00  ? 164 GLU A CB   164 GLU A CB   1 
ATOM 2386 C CG   . GLU A 1 164 ? 32.015 -8.818  -6.420 1.00 6.00  ? 164 GLU A CG   164 GLU A CG   1 
ATOM 2387 C CD   . GLU A 1 164 ? 31.611 -7.618  -7.230 1.00 6.00  ? 164 GLU A CD   164 GLU A CD   1 
ATOM 2388 O OE1  . GLU A 1 164 ? 31.721 -6.524  -6.731 1.00 6.00  ? 164 GLU A OE1  164 GLU A OE1  1 
ATOM 2389 O OE2  . GLU A 1 164 ? 31.192 -7.796  -8.349 1.00 6.00  ? 164 GLU A OE2  164 GLU A OE2  1 
ATOM 2390 H H    . GLU A 1 164 ? 32.274 -9.517  -3.444 1.00 6.00  ? 164 GLU A H    164 GLU A H    1 
ATOM 2391 H HA   . GLU A 1 164 ? 33.866 -10.625 -5.542 1.00 6.00  ? 164 GLU A HA   164 GLU A HA   1 
ATOM 2392 H HB2  . GLU A 1 164 ? 32.999 -7.792  -4.837 1.00 6.00  ? 164 GLU A HB2  164 GLU A 1HB  1 
ATOM 2393 H HB3  . GLU A 1 164 ? 34.030 -8.168  -6.210 1.00 6.00  ? 164 GLU A HB3  164 GLU A 2HB  1 
ATOM 2394 H HG2  . GLU A 1 164 ? 32.219 -9.647  -7.097 1.00 6.00  ? 164 GLU A HG2  164 GLU A 1HG  1 
ATOM 2395 H HG3  . GLU A 1 164 ? 31.189 -9.109  -5.772 1.00 6.00  ? 164 GLU A HG3  164 GLU A 2HG  1 
ATOM 2396 N N    . ARG A 1 165 ? 36.345 -9.785  -5.190 1.00 5.87  ? 165 ARG A N    165 ARG A N    1 
ATOM 2397 C CA   . ARG A 1 165 ? 37.624 -9.343  -4.775 1.00 5.87  ? 165 ARG A CA   165 ARG A CA   1 
ATOM 2398 C C    . ARG A 1 165 ? 37.777 -7.817  -5.052 1.00 5.87  ? 165 ARG A C    165 ARG A C    1 
ATOM 2399 O O    . ARG A 1 165 ? 37.458 -7.412  -6.295 1.00 5.87  ? 165 ARG A O    165 ARG A O    1 
ATOM 2400 C CB   . ARG A 1 165 ? 38.702 -10.135 -5.500 1.00 5.87  ? 165 ARG A CB   165 ARG A CB   1 
ATOM 2401 C CG   . ARG A 1 165 ? 40.128 -9.758  -5.133 1.00 5.87  ? 165 ARG A CG   165 ARG A CG   1 
ATOM 2402 C CD   . ARG A 1 165 ? 41.109 -10.740 -5.660 1.00 5.87  ? 165 ARG A CD   165 ARG A CD   1 
ATOM 2403 N NE   . ARG A 1 165 ? 41.025 -12.016 -4.966 1.00 5.87  ? 165 ARG A NE   165 ARG A NE   1 
ATOM 2404 C CZ   . ARG A 1 165 ? 41.717 -13.120 -5.309 1.00 5.87  ? 165 ARG A CZ   165 ARG A CZ   1 
ATOM 2405 N NH1  . ARG A 1 165 ? 42.538 -13.089 -6.335 1.00 5.87  ? 165 ARG A NH1  165 ARG A NH1  1 
ATOM 2406 N NH2  . ARG A 1 165 ? 41.571 -14.234 -4.613 1.00 5.87  ? 165 ARG A NH2  165 ARG A NH2  1 
ATOM 2407 H H    . ARG A 1 165 ? 36.174 -10.136 -6.114 1.00 5.87  ? 165 ARG A H    165 ARG A H    1 
ATOM 2408 H HA   . ARG A 1 165 ? 37.718 -9.515  -3.703 1.00 5.87  ? 165 ARG A HA   165 ARG A HA   1 
ATOM 2409 H HB2  . ARG A 1 165 ? 38.577 -11.196 -5.289 1.00 5.87  ? 165 ARG A HB2  165 ARG A 1HB  1 
ATOM 2410 H HB3  . ARG A 1 165 ? 38.591 -10.000 -6.576 1.00 5.87  ? 165 ARG A HB3  165 ARG A 2HB  1 
ATOM 2411 H HG2  . ARG A 1 165 ? 40.365 -8.779  -5.551 1.00 5.87  ? 165 ARG A HG2  165 ARG A 1HG  1 
ATOM 2412 H HG3  . ARG A 1 165 ? 40.228 -9.722  -4.047 1.00 5.87  ? 165 ARG A HG3  165 ARG A 2HG  1 
ATOM 2413 H HD2  . ARG A 1 165 ? 40.917 -10.915 -6.718 1.00 5.87  ? 165 ARG A HD2  165 ARG A 1HD  1 
ATOM 2414 H HD3  . ARG A 1 165 ? 42.119 -10.350 -5.534 1.00 5.87  ? 165 ARG A HD3  165 ARG A 2HD  1 
ATOM 2415 H HE   . ARG A 1 165 ? 40.404 -12.078 -4.171 1.00 5.87  ? 165 ARG A HE   165 ARG A HE   1 
ATOM 2416 H HH11 . ARG A 1 165 ? 42.651 -12.238 -6.867 1.00 5.87  ? 165 ARG A HH11 165 ARG A 1HH1 1 
ATOM 2417 H HH12 . ARG A 1 165 ? 43.057 -13.917 -6.592 1.00 5.87  ? 165 ARG A HH12 165 ARG A 2HH1 1 
ATOM 2418 H HH21 . ARG A 1 165 ? 40.939 -14.258 -3.824 1.00 5.87  ? 165 ARG A HH21 165 ARG A 1HH2 1 
ATOM 2419 H HH22 . ARG A 1 165 ? 42.089 -15.061 -4.869 1.00 5.87  ? 165 ARG A HH22 165 ARG A 2HH2 1 
ATOM 2420 N N    . ALA A 1 166 ? 38.315 -7.047  -3.856 1.00 5.73  ? 166 ALA A N    166 ALA A N    1 
ATOM 2421 C CA   . ALA A 1 166 ? 38.588 -5.672  -3.983 1.00 5.73  ? 166 ALA A CA   166 ALA A CA   1 
ATOM 2422 C C    . ALA A 1 166 ? 40.090 -5.403  -3.811 1.00 5.73  ? 166 ALA A C    166 ALA A C    1 
ATOM 2423 O O    . ALA A 1 166 ? 40.599 -5.959  -2.698 1.00 5.73  ? 166 ALA A O    166 ALA A O    1 
ATOM 2424 C CB   . ALA A 1 166 ? 37.763 -4.892  -2.970 1.00 5.73  ? 166 ALA A CB   166 ALA A CB   1 
ATOM 2425 H H    . ALA A 1 166 ? 38.560 -7.517  -3.096 1.00 5.73  ? 166 ALA A H    166 ALA A H    1 
ATOM 2426 H HA   . ALA A 1 166 ? 38.307 -5.363  -4.990 1.00 5.73  ? 166 ALA A HA   166 ALA A HA   1 
ATOM 2427 H HB1  . ALA A 1 166 ? 37.958 -3.826  -3.085 1.00 5.73  ? 166 ALA A HB1  166 ALA A 1HB  1 
ATOM 2428 H HB2  . ALA A 1 166 ? 36.703 -5.087  -3.136 1.00 5.73  ? 166 ALA A HB2  166 ALA A 2HB  1 
ATOM 2429 H HB3  . ALA A 1 166 ? 38.035 -5.204  -1.963 1.00 5.73  ? 166 ALA A HB3  166 ALA A 3HB  1 
ATOM 2430 N N    . THR A 1 167 ? 40.692 -4.525  -4.916 1.00 5.60  ? 167 THR A N    167 THR A N    1 
ATOM 2431 C CA   . THR A 1 167 ? 42.033 -4.072  -4.750 1.00 5.60  ? 167 THR A CA   167 THR A CA   1 
ATOM 2432 C C    . THR A 1 167 ? 41.999 -2.582  -4.296 1.00 5.60  ? 167 THR A C    167 THR A C    1 
ATOM 2433 O O    . THR A 1 167 ? 41.150 -1.834  -4.985 1.00 5.60  ? 167 THR A O    167 THR A O    1 
ATOM 2434 C CB   . THR A 1 167 ? 42.834 -4.241  -6.054 1.00 5.60  ? 167 THR A CB   167 THR A CB   1 
ATOM 2435 O OG1  . THR A 1 167 ? 42.155 -3.573  -7.126 1.00 5.60  ? 167 THR A OG1  167 THR A OG1  1 
ATOM 2436 C CG2  . THR A 1 167 ? 42.990 -5.714  -6.398 1.00 5.60  ? 167 THR A CG2  167 THR A CG2  1 
ATOM 2437 H H    . THR A 1 167 ? 40.160 -4.273  -5.733 1.00 5.60  ? 167 THR A H    167 THR A H    1 
ATOM 2438 H HA   . THR A 1 167 ? 42.507 -4.672  -3.974 1.00 5.60  ? 167 THR A HA   167 THR A HA   1 
ATOM 2439 H HB   . THR A 1 167 ? 43.822 -3.795  -5.935 1.00 5.60  ? 167 THR A HB   167 THR A HB   1 
ATOM 2440 H HG1  . THR A 1 167 ? 42.777 -3.391  -7.834 1.00 5.60  ? 167 THR A HG1  167 THR A HG1  1 
ATOM 2441 H HG21 . THR A 1 167 ? 43.560 -5.814  -7.322 1.00 5.60  ? 167 THR A HG21 167 THR A 1HG2 1 
ATOM 2442 H HG22 . THR A 1 167 ? 43.517 -6.222  -5.590 1.00 5.60  ? 167 THR A HG22 167 THR A 2HG2 1 
ATOM 2443 H HG23 . THR A 1 167 ? 42.007 -6.163  -6.528 1.00 5.60  ? 167 THR A HG23 167 THR A 3HG2 1 
ATOM 2444 N N    . ILE A 1 168 ? 42.873 -2.255  -3.042 1.00 5.46  ? 168 ILE A N    168 ILE A N    1 
ATOM 2445 C CA   . ILE A 1 168 ? 43.004 -1.018  -2.566 1.00 5.46  ? 168 ILE A CA   168 ILE A CA   1 
ATOM 2446 C C    . ILE A 1 168 ? 44.435 -0.538  -2.816 1.00 5.46  ? 168 ILE A C    168 ILE A C    1 
ATOM 2447 O O    . ILE A 1 168 ? 45.389 -1.194  -2.140 1.00 5.46  ? 168 ILE A O    168 ILE A O    1 
ATOM 2448 C CB   . ILE A 1 168 ? 42.641 -1.001  -1.070 1.00 5.46  ? 168 ILE A CB   168 ILE A CB   1 
ATOM 2449 C CG1  . ILE A 1 168 ? 41.127 -1.137  -0.886 1.00 5.46  ? 168 ILE A CG1  168 ILE A CG1  1 
ATOM 2450 C CG2  . ILE A 1 168 ? 43.148 0.275   -0.415 1.00 5.46  ? 168 ILE A CG2  168 ILE A CG2  1 
ATOM 2451 C CD1  . ILE A 1 168 ? 40.710 -1.449  0.533  1.00 5.46  ? 168 ILE A CD1  168 ILE A CD1  1 
ATOM 2452 H H    . ILE A 1 168 ? 43.351 -2.891  -2.661 1.00 5.46  ? 168 ILE A H    168 ILE A H    1 
ATOM 2453 H HA   . ILE A 1 168 ? 42.319 -0.365  -3.107 1.00 5.46  ? 168 ILE A HA   168 ILE A HA   1 
ATOM 2454 H HB   . ILE A 1 168 ? 43.097 -1.858  -0.576 1.00 5.46  ? 168 ILE A HB   168 ILE A HB   1 
ATOM 2455 H HG12 . ILE A 1 168 ? 40.640 -0.211  -1.190 1.00 5.46  ? 168 ILE A HG12 168 ILE A 1HG1 1 
ATOM 2456 H HG13 . ILE A 1 168 ? 40.752 -1.930  -1.533 1.00 5.46  ? 168 ILE A HG13 168 ILE A 2HG1 1 
ATOM 2457 H HG21 . ILE A 1 168 ? 42.882 0.271   0.642  1.00 5.46  ? 168 ILE A HG21 168 ILE A 1HG2 1 
ATOM 2458 H HG22 . ILE A 1 168 ? 44.231 0.330   -0.516 1.00 5.46  ? 168 ILE A HG22 168 ILE A 2HG2 1 
ATOM 2459 H HG23 . ILE A 1 168 ? 42.693 1.139   -0.900 1.00 5.46  ? 168 ILE A HG23 168 ILE A 3HG2 1 
ATOM 2460 H HD11 . ILE A 1 168 ? 39.624 -1.530  0.583  1.00 5.46  ? 168 ILE A HD11 168 ILE A 1HD1 1 
ATOM 2461 H HD12 . ILE A 1 168 ? 41.160 -2.392  0.846  1.00 5.46  ? 168 ILE A HD12 168 ILE A 2HD1 1 
ATOM 2462 H HD13 . ILE A 1 168 ? 41.044 -0.650  1.194  1.00 5.46  ? 168 ILE A HD13 168 ILE A 3HD1 1 
ATOM 2463 N N    . ASN A 1 169 ? 44.583 0.573   -3.923 1.00 5.38  ? 169 ASN A N    169 ASN A N    1 
ATOM 2464 C CA   . ASN A 1 169 ? 45.869 1.109   -4.088 1.00 5.38  ? 169 ASN A CA   169 ASN A CA   1 
ATOM 2465 C C    . ASN A 1 169 ? 46.199 2.343   -3.212 1.00 5.38  ? 169 ASN A C    169 ASN A C    1 
ATOM 2466 O O    . ASN A 1 169 ? 45.078 2.948   -2.834 1.00 5.38  ? 169 ASN A O    169 ASN A O    1 
ATOM 2467 C CB   . ASN A 1 169 ? 46.056 1.427   -5.561 1.00 5.38  ? 169 ASN A CB   169 ASN A CB   1 
ATOM 2468 C CG   . ASN A 1 169 ? 45.969 0.204   -6.431 1.00 5.38  ? 169 ASN A CG   169 ASN A CG   1 
ATOM 2469 O OD1  . ASN A 1 169 ? 46.531 -0.847  -6.104 1.00 5.38  ? 169 ASN A OD1  169 ASN A OD1  1 
ATOM 2470 N ND2  . ASN A 1 169 ? 45.275 0.321   -7.535 1.00 5.38  ? 169 ASN A ND2  169 ASN A ND2  1 
ATOM 2471 H H    . ASN A 1 169 ? 43.801 0.927   -4.445 1.00 5.38  ? 169 ASN A H    169 ASN A H    1 
ATOM 2472 H HA   . ASN A 1 169 ? 46.599 0.361   -3.775 1.00 5.38  ? 169 ASN A HA   169 ASN A HA   1 
ATOM 2473 H HB2  . ASN A 1 169 ? 45.294 2.140   -5.879 1.00 5.38  ? 169 ASN A HB2  169 ASN A 1HB  1 
ATOM 2474 H HB3  . ASN A 1 169 ? 47.027 1.897   -5.711 1.00 5.38  ? 169 ASN A HB3  169 ASN A 2HB  1 
ATOM 2475 H HD21 . ASN A 1 169 ? 45.183 -0.460  -8.153 1.00 5.38  ? 169 ASN A HD21 169 ASN A 1HD2 1 
ATOM 2476 H HD22 . ASN A 1 169 ? 44.837 1.191   -7.760 1.00 5.38  ? 169 ASN A HD22 169 ASN A 2HD2 1 
ATOM 2477 N N    . CYS A 1 170 ? 47.675 2.541   -2.770 1.00 5.27  ? 170 CYS A N    170 CYS A N    1 
ATOM 2478 C CA   . CYS A 1 170 ? 48.014 3.646   -2.113 1.00 5.27  ? 170 CYS A CA   170 CYS A CA   1 
ATOM 2479 C C    . CYS A 1 170 ? 49.439 4.049   -2.510 1.00 5.27  ? 170 CYS A C    170 CYS A C    1 
ATOM 2480 O O    . CYS A 1 170 ? 50.318 3.043   -2.644 1.00 5.27  ? 170 CYS A O    170 CYS A O    1 
ATOM 2481 C CB   . CYS A 1 170 ? 47.893 3.392   -0.610 1.00 5.27  ? 170 CYS A CB   170 CYS A CB   1 
ATOM 2482 S SG   . CYS A 1 170 ? 47.492 4.867   0.358  1.00 5.27  ? 170 CYS A SG   170 CYS A SG   1 
ATOM 2483 H H    . CYS A 1 170 ? 48.310 2.041   -3.129 1.00 5.27  ? 170 CYS A H    170 CYS A H    1 
ATOM 2484 H HA   . CYS A 1 170 ? 47.328 4.444   -2.400 1.00 5.27  ? 170 CYS A HA   170 CYS A HA   1 
ATOM 2485 H HB2  . CYS A 1 170 ? 47.117 2.648   -0.428 1.00 5.27  ? 170 CYS A HB2  170 CYS A 1HB  1 
ATOM 2486 H HB3  . CYS A 1 170 ? 48.831 2.986   -0.233 1.00 5.27  ? 170 CYS A HB3  170 CYS A 2HB  1 
ATOM 2487 H HG   . CYS A 1 170 ? 46.480 5.265   -0.407 1.00 5.27  ? 170 CYS A HG   170 CYS A HG   1 
ATOM 2488 N N    . LYS A 1 171 ? 49.623 5.530   -2.847 1.00 4.98  ? 171 LYS A N    171 LYS A N    1 
ATOM 2489 C CA   . LYS A 1 171 ? 50.873 5.934   -3.375 1.00 4.98  ? 171 LYS A CA   171 LYS A CA   1 
ATOM 2490 C C    . LYS A 1 171 ? 51.716 6.674   -2.375 1.00 4.98  ? 171 LYS A C    171 LYS A C    1 
ATOM 2491 O O    . LYS A 1 171 ? 50.986 7.647   -1.983 1.00 4.98  ? 171 LYS A O    171 LYS A O    1 
ATOM 2492 C CB   . LYS A 1 171 ? 50.653 6.799   -4.617 1.00 4.98  ? 171 LYS A CB   171 LYS A CB   1 
ATOM 2493 C CG   . LYS A 1 171 ? 51.933 7.323   -5.255 1.00 4.98  ? 171 LYS A CG   171 LYS A CG   1 
ATOM 2494 C CD   . LYS A 1 171 ? 51.681 7.824   -6.669 1.00 4.98  ? 171 LYS A CD   171 LYS A CD   1 
ATOM 2495 C CE   . LYS A 1 171 ? 51.481 6.668   -7.639 1.00 4.98  ? 171 LYS A CE   171 LYS A CE   1 
ATOM 2496 N NZ   . LYS A 1 171 ? 52.715 5.852   -7.793 1.00 4.98  ? 171 LYS A NZ   171 LYS A NZ   1 
ATOM 2497 H H    . LYS A 1 171 ? 49.088 6.319   -2.400 1.00 4.98  ? 171 LYS A H    171 LYS A H    1 
ATOM 2498 H HA   . LYS A 1 171 ? 51.434 5.043   -3.658 1.00 4.98  ? 171 LYS A HA   171 LYS A HA   1 
ATOM 2499 H HB2  . LYS A 1 171 ? 50.115 6.223   -5.371 1.00 4.98  ? 171 LYS A HB2  171 LYS A 1HB  1 
ATOM 2500 H HB3  . LYS A 1 171 ? 50.032 7.657   -4.358 1.00 4.98  ? 171 LYS A HB3  171 LYS A 2HB  1 
ATOM 2501 H HG2  . LYS A 1 171 ? 52.330 8.142   -4.654 1.00 4.98  ? 171 LYS A HG2  171 LYS A 1HG  1 
ATOM 2502 H HG3  . LYS A 1 171 ? 52.675 6.527   -5.287 1.00 4.98  ? 171 LYS A HG3  171 LYS A 2HG  1 
ATOM 2503 H HD2  . LYS A 1 171 ? 50.791 8.454   -6.679 1.00 4.98  ? 171 LYS A HD2  171 LYS A 1HD  1 
ATOM 2504 H HD3  . LYS A 1 171 ? 52.531 8.420   -7.000 1.00 4.98  ? 171 LYS A HD3  171 LYS A 2HD  1 
ATOM 2505 H HE2  . LYS A 1 171 ? 50.678 6.027   -7.279 1.00 4.98  ? 171 LYS A HE2  171 LYS A 1HE  1 
ATOM 2506 H HE3  . LYS A 1 171 ? 51.194 7.058   -8.615 1.00 4.98  ? 171 LYS A HE3  171 LYS A 2HE  1 
ATOM 2507 H HZ1  . LYS A 1 171 ? 52.541 5.098   -8.443 1.00 4.98  ? 171 LYS A HZ1  171 LYS A 1HZ  1 
ATOM 2508 H HZ2  . LYS A 1 171 ? 53.463 6.433   -8.145 1.00 4.98  ? 171 LYS A HZ2  171 LYS A 2HZ  1 
ATOM 2509 H HZ3  . LYS A 1 171 ? 52.980 5.469   -6.897 1.00 4.98  ? 171 LYS A HZ3  171 LYS A 3HZ  1 
ATOM 2510 N N    . SER A 1 172 ? 53.075 6.095   -1.937 1.00 4.32  ? 172 SER A N    172 SER A N    1 
ATOM 2511 C CA   . SER A 1 172 ? 53.856 6.812   -1.051 1.00 4.32  ? 172 SER A CA   172 SER A CA   1 
ATOM 2512 C C    . SER A 1 172 ? 54.569 7.896   -1.787 1.00 4.32  ? 172 SER A C    172 SER A C    1 
ATOM 2513 O O    . SER A 1 172 ? 54.511 7.754   -3.097 1.00 4.32  ? 172 SER A O    172 SER A O    1 
ATOM 2514 C CB   . SER A 1 172 ? 54.839 5.887   -0.361 1.00 4.32  ? 172 SER A CB   172 SER A CB   1 
ATOM 2515 O OG   . SER A 1 172 ? 54.169 4.917   0.396  1.00 4.32  ? 172 SER A OG   172 SER A OG   1 
ATOM 2516 H H    . SER A 1 172 ? 53.430 5.306   -2.245 1.00 4.32  ? 172 SER A H    172 SER A H    1 
ATOM 2517 H HA   . SER A 1 172 ? 53.205 7.260   -0.299 1.00 4.32  ? 172 SER A HA   172 SER A HA   1 
ATOM 2518 H HB2  . SER A 1 172 ? 55.466 5.400   -1.108 1.00 4.32  ? 172 SER A HB2  172 SER A 1HB  1 
ATOM 2519 H HB3  . SER A 1 172 ? 55.494 6.469   0.286  1.00 4.32  ? 172 SER A HB3  172 SER A 2HB  1 
ATOM 2520 H HG   . SER A 1 172 ? 53.893 5.356   1.204  1.00 4.32  ? 172 SER A HG   172 SER A HG   1 
ATOM 2521 N N    . SER A 1 173 ? 55.221 8.935   -0.892 1.00 4.28  ? 173 SER A N    173 SER A N    1 
ATOM 2522 C CA   . SER A 1 173 ? 56.137 9.892   -1.428 1.00 4.28  ? 173 SER A CA   173 SER A CA   1 
ATOM 2523 C C    . SER A 1 173 ? 57.094 9.703   -0.100 1.00 4.28  ? 173 SER A C    173 SER A C    1 
ATOM 2524 O O    . SER A 1 173 ? 56.879 10.440  1.147  1.00 4.28  ? 173 SER A O    173 SER A O    1 
ATOM 2525 C CB   . SER A 1 173 ? 55.550 11.273  -1.643 1.00 4.28  ? 173 SER A CB   173 SER A CB   1 
ATOM 2526 O OG   . SER A 1 173 ? 56.513 12.155  -2.152 1.00 4.28  ? 173 SER A OG   173 SER A OG   1 
ATOM 2527 H H    . SER A 1 173 ? 55.125 8.917   0.017  1.00 4.28  ? 173 SER A H    173 SER A H    1 
ATOM 2528 H HA   . SER A 1 173 ? 56.474 9.539   -2.404 1.00 4.28  ? 173 SER A HA   173 SER A HA   1 
ATOM 2529 H HB2  . SER A 1 173 ? 54.711 11.208  -2.335 1.00 4.28  ? 173 SER A HB2  173 SER A 1HB  1 
ATOM 2530 H HB3  . SER A 1 173 ? 55.165 11.655  -0.699 1.00 4.28  ? 173 SER A HB3  173 SER A 2HB  1 
ATOM 2531 H HG   . SER A 1 173 ? 57.332 11.942  -1.698 1.00 4.28  ? 173 SER A HG   173 SER A HG   1 
ATOM 2532 N N    . GLN A 1 174 ? 58.334 9.109   -0.648 1.00 4.31  ? 174 GLN A N    174 GLN A N    1 
ATOM 2533 C CA   . GLN A 1 174 ? 59.505 8.718   0.072  1.00 4.31  ? 174 GLN A CA   174 GLN A CA   1 
ATOM 2534 C C    . GLN A 1 174 ? 60.239 9.609   0.829  1.00 4.31  ? 174 GLN A C    174 GLN A C    1 
ATOM 2535 O O    . GLN A 1 174 ? 60.896 10.492  0.115  1.00 4.31  ? 174 GLN A O    174 GLN A O    1 
ATOM 2536 C CB   . GLN A 1 174 ? 60.516 8.101   -0.897 1.00 4.31  ? 174 GLN A CB   174 GLN A CB   1 
ATOM 2537 C CG   . GLN A 1 174 ? 60.951 9.030   -2.018 1.00 4.31  ? 174 GLN A CG   174 GLN A CG   1 
ATOM 2538 C CD   . GLN A 1 174 ? 59.985 9.018   -3.187 1.00 4.31  ? 174 GLN A CD   174 GLN A CD   1 
ATOM 2539 O OE1  . GLN A 1 174 ? 58.770 8.909   -3.005 1.00 4.31  ? 174 GLN A OE1  174 GLN A OE1  1 
ATOM 2540 N NE2  . GLN A 1 174 ? 60.521 9.131   -4.397 1.00 4.31  ? 174 GLN A NE2  174 GLN A NE2  1 
ATOM 2541 H H    . GLN A 1 174 ? 58.306 8.721   -1.571 1.00 4.31  ? 174 GLN A H    174 GLN A H    1 
ATOM 2542 H HA   . GLN A 1 174 ? 59.221 7.972   0.815  1.00 4.31  ? 174 GLN A HA   174 GLN A HA   1 
ATOM 2543 H HB2  . GLN A 1 174 ? 61.407 7.796   -0.348 1.00 4.31  ? 174 GLN A HB2  174 GLN A 1HB  1 
ATOM 2544 H HB3  . GLN A 1 174 ? 60.088 7.206   -1.349 1.00 4.31  ? 174 GLN A HB3  174 GLN A 2HB  1 
ATOM 2545 H HG2  . GLN A 1 174 ? 61.008 10.047  -1.631 1.00 4.31  ? 174 GLN A HG2  174 GLN A 1HG  1 
ATOM 2546 H HG3  . GLN A 1 174 ? 61.930 8.713   -2.379 1.00 4.31  ? 174 GLN A HG3  174 GLN A 2HG  1 
ATOM 2547 H HE21 . GLN A 1 174 ? 59.934 9.129   -5.207 1.00 4.31  ? 174 GLN A HE21 174 GLN A 1HE2 1 
ATOM 2548 H HE22 . GLN A 1 174 ? 61.512 9.217   -4.500 1.00 4.31  ? 174 GLN A HE22 174 GLN A 2HE2 1 
ATOM 2549 N N    . SER A 1 175 ? 60.498 8.825   2.175  1.00 5.69  ? 175 SER A N    175 SER A N    1 
ATOM 2550 C CA   . SER A 1 175 ? 61.137 8.897   3.580  1.00 5.69  ? 175 SER A CA   175 SER A CA   1 
ATOM 2551 C C    . SER A 1 175 ? 62.169 9.196   2.635  1.00 5.69  ? 175 SER A C    175 SER A C    1 
ATOM 2552 O O    . SER A 1 175 ? 62.353 8.063   1.962  1.00 5.69  ? 175 SER A O    175 SER A O    1 
ATOM 2553 C CB   . SER A 1 175 ? 61.297 7.645   4.420  1.00 5.69  ? 175 SER A CB   175 SER A CB   1 
ATOM 2554 O OG   . SER A 1 175 ? 61.940 7.932   5.632  1.00 5.69  ? 175 SER A OG   175 SER A OG   1 
ATOM 2555 H H    . SER A 1 175 ? 59.874 8.059   2.165  1.00 5.69  ? 175 SER A H    175 SER A H    1 
ATOM 2556 H HA   . SER A 1 175 ? 60.525 9.548   4.206  1.00 5.69  ? 175 SER A HA   175 SER A HA   1 
ATOM 2557 H HG   . SER A 1 175 ? 62.245 7.089   5.976  1.00 5.69  ? 175 SER A HG   175 SER A HG   1 
ATOM 2558 H 1HB  . SER A 1 175 ? 60.317 7.213   4.619  1.00 5.69  ? 175 SER A 1HB  175 SER A 1HB  1 
ATOM 2559 H 2HB  . SER A 1 175 ? 61.874 6.907   3.866  1.00 5.69  ? 175 SER A 2HB  175 SER A 2HB  1 
ATOM 2560 N N    . VAL A 1 176 ? 62.999 10.461  2.933  1.00 5.38  ? 176 VAL A N    176 VAL A N    1 
ATOM 2561 C CA   . VAL A 1 176 ? 63.957 11.149  2.191  1.00 5.38  ? 176 VAL A CA   176 VAL A CA   1 
ATOM 2562 C C    . VAL A 1 176 ? 65.036 10.219  1.931  1.00 5.38  ? 176 VAL A C    176 VAL A C    1 
ATOM 2563 O O    . VAL A 1 176 ? 66.261 10.474  2.359  1.00 5.38  ? 176 VAL A O    176 VAL A O    1 
ATOM 2564 C CB   . VAL A 1 176 ? 64.485 12.381  2.950  1.00 5.38  ? 176 VAL A CB   176 VAL A CB   1 
ATOM 2565 C CG1  . VAL A 1 176 ? 63.359 13.372  3.205  1.00 5.38  ? 176 VAL A CG1  176 VAL A CG1  1 
ATOM 2566 C CG2  . VAL A 1 176 ? 65.127 11.946  4.259  1.00 5.38  ? 176 VAL A CG2  176 VAL A CG2  1 
ATOM 2567 H H    . VAL A 1 176 ? 62.653 11.274  3.465  1.00 5.38  ? 176 VAL A H    176 VAL A H    1 
ATOM 2568 H HA   . VAL A 1 176 ? 63.496 11.493  1.265  1.00 5.38  ? 176 VAL A HA   176 VAL A HA   1 
ATOM 2569 H HB   . VAL A 1 176 ? 65.226 12.887  2.332  1.00 5.38  ? 176 VAL A HB   176 VAL A HB   1 
ATOM 2570 H HG11 . VAL A 1 176 ? 63.750 14.237  3.742  1.00 5.38  ? 176 VAL A HG11 176 VAL A 1HG1 1 
ATOM 2571 H HG12 . VAL A 1 176 ? 62.938 13.696  2.253  1.00 5.38  ? 176 VAL A HG12 176 VAL A 2HG1 1 
ATOM 2572 H HG13 . VAL A 1 176 ? 62.582 12.895  3.802  1.00 5.38  ? 176 VAL A HG13 176 VAL A 3HG1 1 
ATOM 2573 H HG21 . VAL A 1 176 ? 65.498 12.822  4.790  1.00 5.38  ? 176 VAL A HG21 176 VAL A 1HG2 1 
ATOM 2574 H HG22 . VAL A 1 176 ? 64.387 11.434  4.875  1.00 5.38  ? 176 VAL A HG22 176 VAL A 2HG2 1 
ATOM 2575 H HG23 . VAL A 1 176 ? 65.956 11.270  4.051  1.00 5.38  ? 176 VAL A HG23 176 VAL A 3HG2 1 
ATOM 2576 N N    . LEU A 1 177 ? 64.393 9.350   0.759  1.00 5.63  ? 177 LEU A N    177 LEU A N    1 
ATOM 2577 C CA   . LEU A 1 177 ? 64.945 8.263   -0.177 1.00 5.63  ? 177 LEU A CA   177 LEU A CA   1 
ATOM 2578 C C    . LEU A 1 177 ? 65.817 7.309   0.499  1.00 5.63  ? 177 LEU A C    177 LEU A C    1 
ATOM 2579 O O    . LEU A 1 177 ? 66.722 6.647   -0.189 1.00 5.63  ? 177 LEU A O    177 LEU A O    1 
ATOM 2580 C CB   . LEU A 1 177 ? 65.752 8.863   -1.335 1.00 5.63  ? 177 LEU A CB   177 LEU A CB   1 
ATOM 2581 C CG   . LEU A 1 177 ? 64.927 9.512   -2.454 1.00 5.63  ? 177 LEU A CG   177 LEU A CG   1 
ATOM 2582 C CD1  . LEU A 1 177 ? 64.140 10.687  -1.889 1.00 5.63  ? 177 LEU A CD1  177 LEU A CD1  1 
ATOM 2583 C CD2  . LEU A 1 177 ? 65.855 9.963   -3.572 1.00 5.63  ? 177 LEU A CD2  177 LEU A CD2  1 
ATOM 2584 H H    . LEU A 1 177 ? 63.336 9.420   0.707  1.00 5.63  ? 177 LEU A H    177 LEU A H    1 
ATOM 2585 H HA   . LEU A 1 177 ? 64.105 7.713   -0.601 1.00 5.63  ? 177 LEU A HA   177 LEU A HA   1 
ATOM 2586 H HB2  . LEU A 1 177 ? 66.421 9.622   -0.934 1.00 5.63  ? 177 LEU A HB2  177 LEU A 1HB  1 
ATOM 2587 H HB3  . LEU A 1 177 ? 66.356 8.075   -1.783 1.00 5.63  ? 177 LEU A HB3  177 LEU A 2HB  1 
ATOM 2588 H HG   . LEU A 1 177 ? 64.212 8.788   -2.845 1.00 5.63  ? 177 LEU A HG   177 LEU A HG   1 
ATOM 2589 H HD11 . LEU A 1 177 ? 63.554 11.148  -2.684 1.00 5.63  ? 177 LEU A HD11 177 LEU A 1HD1 1 
ATOM 2590 H HD12 . LEU A 1 177 ? 63.470 10.333  -1.105 1.00 5.63  ? 177 LEU A HD12 177 LEU A 2HD1 1 
ATOM 2591 H HD13 . LEU A 1 177 ? 64.829 11.421  -1.475 1.00 5.63  ? 177 LEU A HD13 177 LEU A 3HD1 1 
ATOM 2592 H HD21 . LEU A 1 177 ? 65.269 10.423  -4.368 1.00 5.63  ? 177 LEU A HD21 177 LEU A 1HD2 1 
ATOM 2593 H HD22 . LEU A 1 177 ? 66.570 10.688  -3.182 1.00 5.63  ? 177 LEU A HD22 177 LEU A 2HD2 1 
ATOM 2594 H HD23 . LEU A 1 177 ? 66.392 9.101   -3.969 1.00 5.63  ? 177 LEU A HD23 177 LEU A 3HD2 1 
ATOM 2595 N N    . TYR A 1 178 ? 65.245 7.236   1.931  1.00 5.76  ? 178 TYR A N    178 TYR A N    1 
ATOM 2596 C CA   . TYR A 1 178 ? 65.889 6.604   3.183  1.00 5.76  ? 178 TYR A CA   178 TYR A CA   1 
ATOM 2597 C C    . TYR A 1 178 ? 66.010 5.175   2.898  1.00 5.76  ? 178 TYR A C    178 TYR A C    1 
ATOM 2598 O O    . TYR A 1 178 ? 65.166 4.605   3.739  1.00 5.76  ? 178 TYR A O    178 TYR A O    1 
ATOM 2599 C CB   . TYR A 1 178 ? 65.076 6.803   4.464  1.00 5.76  ? 178 TYR A CB   178 TYR A CB   1 
ATOM 2600 C CG   . TYR A 1 178 ? 65.775 6.311   5.712  1.00 5.76  ? 178 TYR A CG   178 TYR A CG   1 
ATOM 2601 C CD1  . TYR A 1 178 ? 66.822 7.042   6.255  1.00 5.76  ? 178 TYR A CD1  178 TYR A CD1  1 
ATOM 2602 C CD2  . TYR A 1 178 ? 65.369 5.129   6.314  1.00 5.76  ? 178 TYR A CD2  178 TYR A CD2  1 
ATOM 2603 C CE1  . TYR A 1 178 ? 67.460 6.592   7.395  1.00 5.76  ? 178 TYR A CE1  178 TYR A CE1  1 
ATOM 2604 C CE2  . TYR A 1 178 ? 66.008 4.680   7.454  1.00 5.76  ? 178 TYR A CE2  178 TYR A CE2  1 
ATOM 2605 C CZ   . TYR A 1 178 ? 67.049 5.407   7.994  1.00 5.76  ? 178 TYR A CZ   178 TYR A CZ   1 
ATOM 2606 O OH   . TYR A 1 178 ? 67.684 4.959   9.129  1.00 5.76  ? 178 TYR A OH   178 TYR A OH   1 
ATOM 2607 H H    . TYR A 1 178 ? 64.366 7.625   1.962  1.00 5.76  ? 178 TYR A H    178 TYR A H    1 
ATOM 2608 H HA   . TYR A 1 178 ? 66.860 7.071   3.345  1.00 5.76  ? 178 TYR A HA   178 TYR A HA   1 
ATOM 2609 H HB2  . TYR A 1 178 ? 64.855 7.863   4.594  1.00 5.76  ? 178 TYR A HB2  178 TYR A 1HB  1 
ATOM 2610 H HB3  . TYR A 1 178 ? 64.126 6.278   4.378  1.00 5.76  ? 178 TYR A HB3  178 TYR A 2HB  1 
ATOM 2611 H HD1  . TYR A 1 178 ? 67.141 7.971   5.782  1.00 5.76  ? 178 TYR A HD1  178 TYR A HD1  1 
ATOM 2612 H HD2  . TYR A 1 178 ? 64.548 4.554   5.887  1.00 5.76  ? 178 TYR A HD2  178 TYR A HD2  1 
ATOM 2613 H HE1  . TYR A 1 178 ? 68.282 7.166   7.821  1.00 5.76  ? 178 TYR A HE1  178 TYR A HE1  1 
ATOM 2614 H HE2  . TYR A 1 178 ? 65.689 3.750   7.926  1.00 5.76  ? 178 TYR A HE2  178 TYR A HE2  1 
ATOM 2615 H HH   . TYR A 1 178 ? 68.375 5.580   9.374  1.00 5.76  ? 178 TYR A HH   178 TYR A HH   1 
ATOM 2616 N N    . SER A 1 179 ? 67.126 4.796   1.998  1.00 6.03  ? 179 SER A N    179 SER A N    1 
ATOM 2617 C CA   . SER A 1 179 ? 67.868 3.697   1.549  1.00 6.03  ? 179 SER A CA   179 SER A CA   1 
ATOM 2618 C C    . SER A 1 179 ? 66.648 2.799   1.198  1.00 6.03  ? 179 SER A C    179 SER A C    1 
ATOM 2619 O O    . SER A 1 179 ? 66.371 1.609   1.765  1.00 6.03  ? 179 SER A O    179 SER A O    1 
ATOM 2620 C CB   . SER A 1 179 ? 68.785 3.121   2.611  1.00 6.03  ? 179 SER A CB   179 SER A CB   1 
ATOM 2621 O OG   . SER A 1 179 ? 69.727 4.071   3.029  1.00 6.03  ? 179 SER A OG   179 SER A OG   1 
ATOM 2622 H H    . SER A 1 179 ? 67.439 5.627   1.545  1.00 6.03  ? 179 SER A H    179 SER A H    1 
ATOM 2623 H HA   . SER A 1 179 ? 68.497 4.020   0.718  1.00 6.03  ? 179 SER A HA   179 SER A HA   1 
ATOM 2624 H HB2  . SER A 1 179 ? 68.193 2.793   3.464  1.00 6.03  ? 179 SER A HB2  179 SER A 1HB  1 
ATOM 2625 H HB3  . SER A 1 179 ? 69.298 2.247   2.213  1.00 6.03  ? 179 SER A HB3  179 SER A 2HB  1 
ATOM 2626 H HG   . SER A 1 179 ? 70.588 3.694   2.832  1.00 6.03  ? 179 SER A HG   179 SER A HG   1 
ATOM 2627 N N    . SER A 1 180 ? 65.788 3.709   0.142  1.00 6.70  ? 180 SER A N    180 SER A N    1 
ATOM 2628 C CA   . SER A 1 180 ? 64.568 3.071   -0.412 1.00 6.70  ? 180 SER A CA   180 SER A CA   1 
ATOM 2629 C C    . SER A 1 180 ? 63.356 2.792   0.764  1.00 6.70  ? 180 SER A C    180 SER A C    1 
ATOM 2630 O O    . SER A 1 180 ? 62.591 1.778   0.512  1.00 6.70  ? 180 SER A O    180 SER A O    1 
ATOM 2631 C CB   . SER A 1 180 ? 65.001 1.782   -1.083 1.00 6.70  ? 180 SER A CB   180 SER A CB   1 
ATOM 2632 O OG   . SER A 1 180 ? 65.946 2.031   -2.087 1.00 6.70  ? 180 SER A OG   180 SER A OG   1 
ATOM 2633 H H    . SER A 1 180 ? 66.122 4.596   -0.190 1.00 6.70  ? 180 SER A H    180 SER A H    1 
ATOM 2634 H HA   . SER A 1 180 ? 64.127 3.747   -1.145 1.00 6.70  ? 180 SER A HA   180 SER A HA   1 
ATOM 2635 H HB2  . SER A 1 180 ? 65.425 1.109   -0.338 1.00 6.70  ? 180 SER A HB2  180 SER A 1HB  1 
ATOM 2636 H HB3  . SER A 1 180 ? 64.131 1.286   -1.513 1.00 6.70  ? 180 SER A HB3  180 SER A 2HB  1 
ATOM 2637 H HG   . SER A 1 180 ? 65.720 1.446   -2.814 1.00 6.70  ? 180 SER A HG   180 SER A HG   1 
ATOM 2638 N N    . ILE A 1 181 ? 63.086 3.869   2.117  1.00 5.60  ? 181 ILE A N    181 ILE A N    1 
ATOM 2639 C CA   . ILE A 1 181 ? 61.819 3.185   2.282  1.00 5.60  ? 181 ILE A CA   181 ILE A CA   1 
ATOM 2640 C C    . ILE A 1 181 ? 62.424 1.834   2.402  1.00 5.60  ? 181 ILE A C    181 ILE A C    1 
ATOM 2641 O O    . ILE A 1 181 ? 61.590 0.762   2.434  1.00 5.60  ? 181 ILE A O    181 ILE A O    1 
ATOM 2642 C CB   . ILE A 1 181 ? 60.836 3.310   1.104  1.00 5.60  ? 181 ILE A CB   181 ILE A CB   1 
ATOM 2643 C CG1  . ILE A 1 181 ? 60.153 4.680   1.121  1.00 5.60  ? 181 ILE A CG1  181 ILE A CG1  1 
ATOM 2644 C CG2  . ILE A 1 181 ? 59.802 2.195   1.153  1.00 5.60  ? 181 ILE A CG2  181 ILE A CG2  1 
ATOM 2645 C CD1  . ILE A 1 181 ? 59.282 4.943   -0.086 1.00 5.60  ? 181 ILE A CD1  181 ILE A CD1  1 
ATOM 2646 H H    . ILE A 1 181 ? 63.780 4.298   2.635  1.00 5.60  ? 181 ILE A H    181 ILE A H    1 
ATOM 2647 H HA   . ILE A 1 181 ? 61.309 3.607   3.147  1.00 5.60  ? 181 ILE A HA   181 ILE A HA   1 
ATOM 2648 H HB   . ILE A 1 181 ? 61.384 3.243   0.165  1.00 5.60  ? 181 ILE A HB   181 ILE A HB   1 
ATOM 2649 H HG12 . ILE A 1 181 ? 59.535 4.767   2.014  1.00 5.60  ? 181 ILE A HG12 181 ILE A 1HG1 1 
ATOM 2650 H HG13 . ILE A 1 181 ? 60.910 5.463   1.170  1.00 5.60  ? 181 ILE A HG13 181 ILE A 2HG1 1 
ATOM 2651 H HG21 . ILE A 1 181 ? 59.115 2.299   0.314  1.00 5.60  ? 181 ILE A HG21 181 ILE A 1HG2 1 
ATOM 2652 H HG22 . ILE A 1 181 ? 60.304 1.231   1.094  1.00 5.60  ? 181 ILE A HG22 181 ILE A 2HG2 1 
ATOM 2653 H HG23 . ILE A 1 181 ? 59.245 2.258   2.088  1.00 5.60  ? 181 ILE A HG23 181 ILE A 3HG2 1 
ATOM 2654 H HD11 . ILE A 1 181 ? 58.833 5.933   -0.002 1.00 5.60  ? 181 ILE A HD11 181 ILE A 1HD1 1 
ATOM 2655 H HD12 . ILE A 1 181 ? 59.889 4.895   -0.991 1.00 5.60  ? 181 ILE A HD12 181 ILE A 2HD1 1 
ATOM 2656 H HD13 . ILE A 1 181 ? 58.495 4.191   -0.137 1.00 5.60  ? 181 ILE A HD13 181 ILE A 3HD1 1 
ATOM 2657 N N    . ASN A 1 182 ? 63.590 2.001   3.538  1.00 5.09  ? 182 ASN A N    182 ASN A N    1 
ATOM 2658 C CA   . ASN A 1 182 ? 64.476 1.044   4.112  1.00 5.09  ? 182 ASN A CA   182 ASN A CA   1 
ATOM 2659 C C    . ASN A 1 182 ? 63.464 0.221   5.085  1.00 5.09  ? 182 ASN A C    182 ASN A C    1 
ATOM 2660 O O    . ASN A 1 182 ? 63.266 0.574   6.432  1.00 5.09  ? 182 ASN A O    182 ASN A O    1 
ATOM 2661 C CB   . ASN A 1 182 ? 65.640 1.708   4.823  1.00 5.09  ? 182 ASN A CB   182 ASN A CB   1 
ATOM 2662 C CG   . ASN A 1 182 ? 66.700 0.725   5.238  1.00 5.09  ? 182 ASN A CG   182 ASN A CG   1 
ATOM 2663 O OD1  . ASN A 1 182 ? 66.667 -0.446  4.843  1.00 5.09  ? 182 ASN A OD1  182 ASN A OD1  1 
ATOM 2664 N ND2  . ASN A 1 182 ? 67.639 1.178   6.029  1.00 5.09  ? 182 ASN A ND2  182 ASN A ND2  1 
ATOM 2665 H H    . ASN A 1 182 ? 63.973 2.760   3.805  1.00 5.09  ? 182 ASN A H    182 ASN A H    1 
ATOM 2666 H HA   . ASN A 1 182 ? 64.880 0.422   3.311  1.00 5.09  ? 182 ASN A HA   182 ASN A HA   1 
ATOM 2667 H HB2  . ASN A 1 182 ? 66.090 2.453   4.167  1.00 5.09  ? 182 ASN A HB2  182 ASN A 1HB  1 
ATOM 2668 H HB3  . ASN A 1 182 ? 65.277 2.228   5.709  1.00 5.09  ? 182 ASN A HB3  182 ASN A 2HB  1 
ATOM 2669 H HD21 . ASN A 1 182 ? 68.370 0.569   6.337  1.00 5.09  ? 182 ASN A HD21 182 ASN A 1HD2 1 
ATOM 2670 H HD22 . ASN A 1 182 ? 67.626 2.133   6.324  1.00 5.09  ? 182 ASN A HD22 182 ASN A 2HD2 1 
ATOM 2671 N N    . LYS A 1 183 ? 62.662 -0.780  4.252  1.00 4.34  ? 183 LYS A N    183 LYS A N    1 
ATOM 2672 C CA   . LYS A 1 183 ? 61.788 -1.575  5.097  1.00 4.34  ? 183 LYS A CA   183 LYS A CA   1 
ATOM 2673 C C    . LYS A 1 183 ? 60.693 -0.732  5.990  1.00 4.34  ? 183 LYS A C    183 LYS A C    1 
ATOM 2674 O O    . LYS A 1 183 ? 60.577 -1.049  7.327  1.00 4.34  ? 183 LYS A O    183 LYS A O    1 
ATOM 2675 C CB   . LYS A 1 183 ? 62.685 -2.428  5.995  1.00 4.34  ? 183 LYS A CB   183 LYS A CB   1 
ATOM 2676 C CG   . LYS A 1 183 ? 63.616 -3.369  5.243  1.00 4.34  ? 183 LYS A CG   183 LYS A CG   1 
ATOM 2677 C CD   . LYS A 1 183 ? 64.381 -4.272  6.199  1.00 4.34  ? 183 LYS A CD   183 LYS A CD   1 
ATOM 2678 C CE   . LYS A 1 183 ? 65.332 -5.194  5.451  1.00 4.34  ? 183 LYS A CE   183 LYS A CE   1 
ATOM 2679 N NZ   . LYS A 1 183 ? 66.092 -6.079  6.375  1.00 4.34  ? 183 LYS A NZ   183 LYS A NZ   1 
ATOM 2680 H H    . LYS A 1 183 ? 62.549 -0.620  3.286  1.00 4.34  ? 183 LYS A H    183 LYS A H    1 
ATOM 2681 H HA   . LYS A 1 183 ? 61.177 -2.214  4.458  1.00 4.34  ? 183 LYS A HA   183 LYS A HA   1 
ATOM 2682 H HB2  . LYS A 1 183 ? 63.299 -1.778  6.619  1.00 4.34  ? 183 LYS A HB2  183 LYS A 1HB  1 
ATOM 2683 H HB3  . LYS A 1 183 ? 62.066 -3.031  6.660  1.00 4.34  ? 183 LYS A HB3  183 LYS A 2HB  1 
ATOM 2684 H HG2  . LYS A 1 183 ? 63.034 -3.989  4.559  1.00 4.34  ? 183 LYS A HG2  183 LYS A 1HG  1 
ATOM 2685 H HG3  . LYS A 1 183 ? 64.328 -2.786  4.659  1.00 4.34  ? 183 LYS A HG3  183 LYS A 2HG  1 
ATOM 2686 H HD2  . LYS A 1 183 ? 64.955 -3.660  6.897  1.00 4.34  ? 183 LYS A HD2  183 LYS A 1HD  1 
ATOM 2687 H HD3  . LYS A 1 183 ? 63.677 -4.878  6.769  1.00 4.34  ? 183 LYS A HD3  183 LYS A 2HD  1 
ATOM 2688 H HE2  . LYS A 1 183 ? 64.767 -5.814  4.757  1.00 4.34  ? 183 LYS A HE2  183 LYS A 1HE  1 
ATOM 2689 H HE3  . LYS A 1 183 ? 66.040 -4.597  4.876  1.00 4.34  ? 183 LYS A HE3  183 LYS A 2HE  1 
ATOM 2690 H HZ1  . LYS A 1 183 ? 66.710 -6.673  5.841  1.00 4.34  ? 183 LYS A HZ1  183 LYS A 1HZ  1 
ATOM 2691 H HZ2  . LYS A 1 183 ? 66.636 -5.513  7.012  1.00 4.34  ? 183 LYS A HZ2  183 LYS A 2HZ  1 
ATOM 2692 H HZ3  . LYS A 1 183 ? 65.447 -6.651  6.900  1.00 4.34  ? 183 LYS A HZ3  183 LYS A 3HZ  1 
ATOM 2693 N N    . ASN A 1 184 ? 60.184 0.504   5.216  1.00 3.78  ? 184 ASN A N    184 ASN A N    1 
ATOM 2694 C CA   . ASN A 1 184 ? 59.156 1.162   5.902  1.00 3.78  ? 184 ASN A CA   184 ASN A CA   1 
ATOM 2695 C C    . ASN A 1 184 ? 58.036 0.008   6.112  1.00 3.78  ? 184 ASN A C    184 ASN A C    1 
ATOM 2696 O O    . ASN A 1 184 ? 57.892 -1.009  5.150  1.00 3.78  ? 184 ASN A O    184 ASN A O    1 
ATOM 2697 C CB   . ASN A 1 184 ? 58.675 2.370   5.120  1.00 3.78  ? 184 ASN A CB   184 ASN A CB   1 
ATOM 2698 C CG   . ASN A 1 184 ? 59.660 3.506   5.147  1.00 3.78  ? 184 ASN A CG   184 ASN A CG   1 
ATOM 2699 O OD1  . ASN A 1 184 ? 59.475 4.521   4.467  1.00 3.78  ? 184 ASN A OD1  184 ASN A OD1  1 
ATOM 2700 N ND2  . ASN A 1 184 ? 60.705 3.354   5.921  1.00 3.78  ? 184 ASN A ND2  184 ASN A ND2  1 
ATOM 2701 H H    . ASN A 1 184 ? 60.424 0.624   4.197  1.00 3.78  ? 184 ASN A H    184 ASN A H    1 
ATOM 2702 H HA   . ASN A 1 184 ? 59.545 1.504   6.863  1.00 3.78  ? 184 ASN A HA   184 ASN A HA   1 
ATOM 2703 H HB2  . ASN A 1 184 ? 58.496 2.085   4.083  1.00 3.78  ? 184 ASN A HB2  184 ASN A 1HB  1 
ATOM 2704 H HB3  . ASN A 1 184 ? 57.727 2.717   5.532  1.00 3.78  ? 184 ASN A HB3  184 ASN A 2HB  1 
ATOM 2705 H HD21 . ASN A 1 184 ? 61.393 4.078   5.979  1.00 3.78  ? 184 ASN A HD21 184 ASN A 1HD2 1 
ATOM 2706 H HD22 . ASN A 1 184 ? 60.814 2.516   6.454  1.00 3.78  ? 184 ASN A HD22 184 ASN A 2HD2 1 
ATOM 2707 N N    . TYR A 1 185 ? 57.390 0.125   7.482  1.00 4.56  ? 185 TYR A N    185 TYR A N    1 
ATOM 2708 C CA   . TYR A 1 185 ? 56.369 -0.697  7.850  1.00 4.56  ? 185 TYR A CA   185 TYR A CA   1 
ATOM 2709 C C    . TYR A 1 185 ? 55.049 -0.071  7.565  1.00 4.56  ? 185 TYR A C    185 TYR A C    1 
ATOM 2710 O O    . TYR A 1 185 ? 55.068 1.225   7.783  1.00 4.56  ? 185 TYR A O    185 TYR A O    1 
ATOM 2711 C CB   . TYR A 1 185 ? 56.508 -1.053  9.332  1.00 4.56  ? 185 TYR A CB   185 TYR A CB   1 
ATOM 2712 C CG   . TYR A 1 185 ? 57.842 -1.671  9.688  1.00 4.56  ? 185 TYR A CG   185 TYR A CG   1 
ATOM 2713 C CD1  . TYR A 1 185 ? 58.938 -0.859  9.940  1.00 4.56  ? 185 TYR A CD1  185 TYR A CD1  1 
ATOM 2714 C CD2  . TYR A 1 185 ? 57.968 -3.050  9.764  1.00 4.56  ? 185 TYR A CD2  185 TYR A CD2  1 
ATOM 2715 C CE1  . TYR A 1 185 ? 60.156 -1.425  10.265 1.00 4.56  ? 185 TYR A CE1  185 TYR A CE1  1 
ATOM 2716 C CE2  . TYR A 1 185 ? 59.186 -3.615  10.089 1.00 4.56  ? 185 TYR A CE2  185 TYR A CE2  1 
ATOM 2717 C CZ   . TYR A 1 185 ? 60.277 -2.808  10.339 1.00 4.56  ? 185 TYR A CZ   185 TYR A CZ   1 
ATOM 2718 O OH   . TYR A 1 185 ? 61.490 -3.371  10.663 1.00 4.56  ? 185 TYR A OH   185 TYR A OH   1 
ATOM 2719 H H    . TYR A 1 185 ? 57.541 0.887   7.993  1.00 4.56  ? 185 TYR A H    185 TYR A H    1 
ATOM 2720 H HA   . TYR A 1 185 ? 56.428 -1.610  7.256  1.00 4.56  ? 185 TYR A HA   185 TYR A HA   1 
ATOM 2721 H HB2  . TYR A 1 185 ? 56.377 -0.154  9.936  1.00 4.56  ? 185 TYR A HB2  185 TYR A 1HB  1 
ATOM 2722 H HB3  . TYR A 1 185 ? 55.722 -1.753  9.613  1.00 4.56  ? 185 TYR A HB3  185 TYR A 2HB  1 
ATOM 2723 H HD1  . TYR A 1 185 ? 58.838 0.225   9.880  1.00 4.56  ? 185 TYR A HD1  185 TYR A HD1  1 
ATOM 2724 H HD2  . TYR A 1 185 ? 57.107 -3.688  9.565  1.00 4.56  ? 185 TYR A HD2  185 TYR A HD2  1 
ATOM 2725 H HE1  . TYR A 1 185 ? 61.017 -0.787  10.463 1.00 4.56  ? 185 TYR A HE1  185 TYR A HE1  1 
ATOM 2726 H HE2  . TYR A 1 185 ? 59.286 -4.700  10.148 1.00 4.56  ? 185 TYR A HE2  185 TYR A HE2  1 
ATOM 2727 H HH   . TYR A 1 185 ? 62.145 -2.677  10.767 1.00 4.56  ? 185 TYR A HH   185 TYR A HH   1 
ATOM 2728 N N    . LEU A 1 186 ? 53.957 -1.027  7.016  1.00 4.96  ? 186 LEU A N    186 LEU A N    1 
ATOM 2729 C CA   . LEU A 1 186 ? 52.687 -0.507  6.658  1.00 4.96  ? 186 LEU A CA   186 LEU A CA   1 
ATOM 2730 C C    . LEU A 1 186 ? 51.585 -1.313  7.371  1.00 4.96  ? 186 LEU A C    186 LEU A C    1 
ATOM 2731 O O    . LEU A 1 186 ? 51.579 -2.619  7.021  1.00 4.96  ? 186 LEU A O    186 LEU A O    1 
ATOM 2732 C CB   . LEU A 1 186 ? 52.512 -0.564  5.135  1.00 4.96  ? 186 LEU A CB   186 LEU A CB   1 
ATOM 2733 C CG   . LEU A 1 186 ? 51.114 -0.208  4.613  1.00 4.96  ? 186 LEU A CG   186 LEU A CG   1 
ATOM 2734 C CD1  . LEU A 1 186 ? 50.735 1.188   5.088  1.00 4.96  ? 186 LEU A CD1  186 LEU A CD1  1 
ATOM 2735 C CD2  . LEU A 1 186 ? 51.104 -0.290  3.093  1.00 4.96  ? 186 LEU A CD2  186 LEU A CD2  1 
ATOM 2736 H H    . LEU A 1 186 ? 54.021 -1.976  7.194  1.00 4.96  ? 186 LEU A H    186 LEU A H    1 
ATOM 2737 H HA   . LEU A 1 186 ? 52.635 0.532   6.981  1.00 4.96  ? 186 LEU A HA   186 LEU A HA   1 
ATOM 2738 H HB2  . LEU A 1 186 ? 53.221 0.124   4.678  1.00 4.96  ? 186 LEU A HB2  186 LEU A 1HB  1 
ATOM 2739 H HB3  . LEU A 1 186 ? 52.745 -1.573  4.796  1.00 4.96  ? 186 LEU A HB3  186 LEU A 2HB  1 
ATOM 2740 H HG   . LEU A 1 186 ? 50.384 -0.908  5.019  1.00 4.96  ? 186 LEU A HG   186 LEU A HG   1 
ATOM 2741 H HD11 . LEU A 1 186 ? 49.741 1.441   4.717  1.00 4.96  ? 186 LEU A HD11 186 LEU A 1HD1 1 
ATOM 2742 H HD12 . LEU A 1 186 ? 50.731 1.213   6.178  1.00 4.96  ? 186 LEU A HD12 186 LEU A 2HD1 1 
ATOM 2743 H HD13 . LEU A 1 186 ? 51.458 1.910   4.710  1.00 4.96  ? 186 LEU A HD13 186 LEU A 3HD1 1 
ATOM 2744 H HD21 . LEU A 1 186 ? 50.110 -0.037  2.722  1.00 4.96  ? 186 LEU A HD21 186 LEU A 1HD2 1 
ATOM 2745 H HD22 . LEU A 1 186 ? 51.832 0.411   2.686  1.00 4.96  ? 186 LEU A HD22 186 LEU A 2HD2 1 
ATOM 2746 H HD23 . LEU A 1 186 ? 51.361 -1.302  2.782  1.00 4.96  ? 186 LEU A HD23 186 LEU A 3HD2 1 
ATOM 2747 N N    . ALA A 1 187 ? 50.671 -0.482  8.319  1.00 5.35  ? 187 ALA A N    187 ALA A N    1 
ATOM 2748 C CA   . ALA A 1 187 ? 49.678 -1.136  9.018  1.00 5.35  ? 187 ALA A CA   187 ALA A CA   1 
ATOM 2749 C C    . ALA A 1 187 ? 48.320 -0.702  8.394  1.00 5.35  ? 187 ALA A C    187 ALA A C    1 
ATOM 2750 O O    . ALA A 1 187 ? 48.010 0.355   8.080  1.00 5.35  ? 187 ALA A O    187 ALA A O    1 
ATOM 2751 C CB   . ALA A 1 187 ? 49.782 -0.808  10.500 1.00 5.35  ? 187 ALA A CB   187 ALA A CB   1 
ATOM 2752 H H    . ALA A 1 187 ? 50.712 0.423   8.274  1.00 5.35  ? 187 ALA A H    187 ALA A H    1 
ATOM 2753 H HA   . ALA A 1 187 ? 49.818 -2.209  8.879  1.00 5.35  ? 187 ALA A HA   187 ALA A HA   1 
ATOM 2754 H HB1  . ALA A 1 187 ? 49.002 -1.339  11.046 1.00 5.35  ? 187 ALA A HB1  187 ALA A 1HB  1 
ATOM 2755 H HB2  . ALA A 1 187 ? 50.759 -1.116  10.873 1.00 5.35  ? 187 ALA A HB2  187 ALA A 2HB  1 
ATOM 2756 H HB3  . ALA A 1 187 ? 49.661 0.264   10.644 1.00 5.35  ? 187 ALA A HB3  187 ALA A 3HB  1 
ATOM 2757 N N    . TRP A 1 188 ? 47.398 -1.577  8.172  1.00 5.54  ? 188 TRP A N    188 TRP A N    1 
ATOM 2758 C CA   . TRP A 1 188 ? 46.034 -1.395  7.738  1.00 5.54  ? 188 TRP A CA   188 TRP A CA   1 
ATOM 2759 C C    . TRP A 1 188 ? 45.187 -1.504  9.058  1.00 5.54  ? 188 TRP A C    188 TRP A C    1 
ATOM 2760 O O    . TRP A 1 188 ? 45.284 -2.707  9.646  1.00 5.54  ? 188 TRP A O    188 TRP A O    1 
ATOM 2761 C CB   . TRP A 1 188 ? 45.629 -2.450  6.706  1.00 5.54  ? 188 TRP A CB   188 TRP A CB   1 
ATOM 2762 C CG   . TRP A 1 188 ? 44.221 -2.298  6.217  1.00 5.54  ? 188 TRP A CG   188 TRP A CG   1 
ATOM 2763 C CD1  . TRP A 1 188 ? 43.482 -1.153  6.201  1.00 5.54  ? 188 TRP A CD1  188 TRP A CD1  1 
ATOM 2764 C CD2  . TRP A 1 188 ? 43.369 -3.332  5.666  1.00 5.54  ? 188 TRP A CD2  188 TRP A CD2  1 
ATOM 2765 N NE1  . TRP A 1 188 ? 42.235 -1.401  5.682  1.00 5.54  ? 188 TRP A NE1  188 TRP A NE1  1 
ATOM 2766 C CE2  . TRP A 1 188 ? 42.149 -2.729  5.348  1.00 5.54  ? 188 TRP A CE2  188 TRP A CE2  1 
ATOM 2767 C CE3  . TRP A 1 188 ? 43.542 -4.700  5.421  1.00 5.54  ? 188 TRP A CE3  188 TRP A CE3  1 
ATOM 2768 C CZ2  . TRP A 1 188 ? 41.099 -3.445  4.796  1.00 5.54  ? 188 TRP A CZ2  188 TRP A CZ2  1 
ATOM 2769 C CZ3  . TRP A 1 188 ? 42.489 -5.417  4.866  1.00 5.54  ? 188 TRP A CZ3  188 TRP A CZ3  1 
ATOM 2770 C CH2  . TRP A 1 188 ? 41.300 -4.805  4.562  1.00 5.54  ? 188 TRP A CH2  188 TRP A CH2  1 
ATOM 2771 H H    . TRP A 1 188 ? 47.648 -2.435  8.315  1.00 5.54  ? 188 TRP A H    188 TRP A H    1 
ATOM 2772 H HA   . TRP A 1 188 ? 45.947 -0.414  7.273  1.00 5.54  ? 188 TRP A HA   188 TRP A HA   1 
ATOM 2773 H HB2  . TRP A 1 188 ? 46.298 -2.394  5.847  1.00 5.54  ? 188 TRP A HB2  188 TRP A 1HB  1 
ATOM 2774 H HB3  . TRP A 1 188 ? 45.736 -3.443  7.141  1.00 5.54  ? 188 TRP A HB3  188 TRP A 2HB  1 
ATOM 2775 H HD1  . TRP A 1 188 ? 43.831 -0.182  6.549  1.00 5.54  ? 188 TRP A HD1  188 TRP A HD1  1 
ATOM 2776 H HE1  . TRP A 1 188 ? 41.500 -0.718  5.565  1.00 5.54  ? 188 TRP A HE1  188 TRP A HE1  1 
ATOM 2777 H HE3  . TRP A 1 188 ? 44.486 -5.190  5.658  1.00 5.54  ? 188 TRP A HE3  188 TRP A HE3  1 
ATOM 2778 H HZ2  . TRP A 1 188 ? 40.146 -2.977  4.548  1.00 5.54  ? 188 TRP A HZ2  188 TRP A HZ2  1 
ATOM 2779 H HZ3  . TRP A 1 188 ? 42.632 -6.482  4.679  1.00 5.54  ? 188 TRP A HZ3  188 TRP A HZ3  1 
ATOM 2780 H HH2  . TRP A 1 188 ? 40.494 -5.398  4.127  1.00 5.54  ? 188 TRP A HH2  188 TRP A HH2  1 
ATOM 2781 N N    . TYR A 1 189 ? 44.368 -0.241  9.420  1.00 5.82  ? 189 TYR A N    189 TYR A N    1 
ATOM 2782 C CA   . TYR A 1 189 ? 43.502 -0.214  10.427 1.00 5.82  ? 189 TYR A CA   189 TYR A CA   1 
ATOM 2783 C C    . TYR A 1 189 ? 42.060 -0.066  9.755  1.00 5.82  ? 189 TYR A C    189 TYR A C    1 
ATOM 2784 O O    . TYR A 1 189 ? 41.930 0.736   8.718  1.00 5.82  ? 189 TYR A O    189 TYR A O    1 
ATOM 2785 C CB   . TYR A 1 189 ? 43.874 0.923   11.381 1.00 5.82  ? 189 TYR A CB   189 TYR A CB   1 
ATOM 2786 C CG   . TYR A 1 189 ? 45.142 0.672   12.166 1.00 5.82  ? 189 TYR A CG   189 TYR A CG   1 
ATOM 2787 C CD1  . TYR A 1 189 ? 46.359 1.131   11.684 1.00 5.82  ? 189 TYR A CD1  189 TYR A CD1  1 
ATOM 2788 C CD2  . TYR A 1 189 ? 45.088 -0.019  13.368 1.00 5.82  ? 189 TYR A CD2  189 TYR A CD2  1 
ATOM 2789 C CE1  . TYR A 1 189 ? 47.517 0.901   12.401 1.00 5.82  ? 189 TYR A CE1  189 TYR A CE1  1 
ATOM 2790 C CE2  . TYR A 1 189 ? 46.246 -0.249  14.085 1.00 5.82  ? 189 TYR A CE2  189 TYR A CE2  1 
ATOM 2791 C CZ   . TYR A 1 189 ? 47.457 0.209   13.605 1.00 5.82  ? 189 TYR A CZ   189 TYR A CZ   1 
ATOM 2792 O OH   . TYR A 1 189 ? 48.610 -0.020  14.319 1.00 5.82  ? 189 TYR A OH   189 TYR A OH   1 
ATOM 2793 H H    . TYR A 1 189 ? 44.481 0.497   8.914  1.00 5.82  ? 189 TYR A H    189 TYR A H    1 
ATOM 2794 H HA   . TYR A 1 189 ? 43.561 -1.164  10.960 1.00 5.82  ? 189 TYR A HA   189 TYR A HA   1 
ATOM 2795 H HB2  . TYR A 1 189 ? 44.002 1.847   10.814 1.00 5.82  ? 189 TYR A HB2  189 TYR A 1HB  1 
ATOM 2796 H HB3  . TYR A 1 189 ? 43.062 1.085   12.089 1.00 5.82  ? 189 TYR A HB3  189 TYR A 2HB  1 
ATOM 2797 H HD1  . TYR A 1 189 ? 46.401 1.674   10.739 1.00 5.82  ? 189 TYR A HD1  189 TYR A HD1  1 
ATOM 2798 H HD2  . TYR A 1 189 ? 44.132 -0.381  13.746 1.00 5.82  ? 189 TYR A HD2  189 TYR A HD2  1 
ATOM 2799 H HE1  . TYR A 1 189 ? 48.473 1.262   12.023 1.00 5.82  ? 189 TYR A HE1  189 TYR A HE1  1 
ATOM 2800 H HE2  . TYR A 1 189 ? 46.204 -0.792  15.029 1.00 5.82  ? 189 TYR A HE2  189 TYR A HE2  1 
ATOM 2801 H HH   . TYR A 1 189 ? 49.305 0.558   13.997 1.00 5.82  ? 189 TYR A HH   189 TYR A HH   1 
ATOM 2802 N N    . GLN A 1 190 ? 40.966 -0.983  10.334 1.00 5.94  ? 190 GLN A N    190 GLN A N    1 
ATOM 2803 C CA   . GLN A 1 190 ? 39.704 -0.819  10.070 1.00 5.94  ? 190 GLN A CA   190 GLN A CA   1 
ATOM 2804 C C    . GLN A 1 190 ? 39.051 -0.043  11.208 1.00 5.94  ? 190 GLN A C    190 GLN A C    1 
ATOM 2805 O O    . GLN A 1 190 ? 39.323 -0.362  12.519 1.00 5.94  ? 190 GLN A O    190 GLN A O    1 
ATOM 2806 C CB   . GLN A 1 190 ? 39.069 -2.195  9.846  1.00 5.94  ? 190 GLN A CB   190 GLN A CB   1 
ATOM 2807 C CG   . GLN A 1 190 ? 37.569 -2.158  9.614  1.00 5.94  ? 190 GLN A CG   190 GLN A CG   1 
ATOM 2808 C CD   . GLN A 1 190 ? 36.965 -3.545  9.511  1.00 5.94  ? 190 GLN A CD   190 GLN A CD   1 
ATOM 2809 O OE1  . GLN A 1 190 ? 37.387 -4.475  10.205 1.00 5.94  ? 190 GLN A OE1  190 GLN A OE1  1 
ATOM 2810 N NE2  . GLN A 1 190 ? 35.971 -3.694  8.642  1.00 5.94  ? 190 GLN A NE2  190 GLN A NE2  1 
ATOM 2811 H H    . GLN A 1 190 ? 41.207 -1.549  11.019 1.00 5.94  ? 190 GLN A H    190 GLN A H    1 
ATOM 2812 H HA   . GLN A 1 190 ? 39.615 -0.225  9.161  1.00 5.94  ? 190 GLN A HA   190 GLN A HA   1 
ATOM 2813 H HB2  . GLN A 1 190 ? 39.532 -2.672  8.982  1.00 5.94  ? 190 GLN A HB2  190 GLN A 1HB  1 
ATOM 2814 H HB3  . GLN A 1 190 ? 39.261 -2.829  10.712 1.00 5.94  ? 190 GLN A HB3  190 GLN A 2HB  1 
ATOM 2815 H HG2  . GLN A 1 190 ? 37.095 -1.640  10.449 1.00 5.94  ? 190 GLN A HG2  190 GLN A 1HG  1 
ATOM 2816 H HG3  . GLN A 1 190 ? 37.368 -1.627  8.683  1.00 5.94  ? 190 GLN A HG3  190 GLN A 2HG  1 
ATOM 2817 H HE21 . GLN A 1 190 ? 35.533 -4.587  8.530  1.00 5.94  ? 190 GLN A HE21 190 GLN A 1HE2 1 
ATOM 2818 H HE22 . GLN A 1 190 ? 35.660 -2.914  8.099  1.00 5.94  ? 190 GLN A HE22 190 GLN A 2HE2 1 
ATOM 2819 N N    . GLN A 1 191 ? 38.233 1.144   10.673 1.00 6.27  ? 191 GLN A N    191 GLN A N    1 
ATOM 2820 C CA   . GLN A 1 191 ? 37.528 1.918   11.701 1.00 6.27  ? 191 GLN A CA   191 GLN A CA   1 
ATOM 2821 C C    . GLN A 1 191 ? 36.029 1.723   11.464 1.00 6.27  ? 191 GLN A C    191 GLN A C    1 
ATOM 2822 O O    . GLN A 1 191 ? 35.416 1.910   10.207 1.00 6.27  ? 191 GLN A O    191 GLN A O    1 
ATOM 2823 C CB   . GLN A 1 191 ? 37.902 3.401   11.648 1.00 6.27  ? 191 GLN A CB   191 GLN A CB   1 
ATOM 2824 C CG   . GLN A 1 191 ? 37.028 4.295   12.510 1.00 6.27  ? 191 GLN A CG   191 GLN A CG   1 
ATOM 2825 C CD   . GLN A 1 191 ? 37.326 4.142   13.990 1.00 6.27  ? 191 GLN A CD   191 GLN A CD   1 
ATOM 2826 O OE1  . GLN A 1 191 ? 38.425 4.460   14.452 1.00 6.27  ? 191 GLN A OE1  191 GLN A OE1  1 
ATOM 2827 N NE2  . GLN A 1 191 ? 36.346 3.653   14.742 1.00 6.27  ? 191 GLN A NE2  191 GLN A NE2  1 
ATOM 2828 H H    . GLN A 1 191 ? 38.171 1.355   9.769  1.00 6.27  ? 191 GLN A H    191 GLN A H    1 
ATOM 2829 H HA   . GLN A 1 191 ? 37.813 1.532   12.680 1.00 6.27  ? 191 GLN A HA   191 GLN A HA   1 
ATOM 2830 H HB2  . GLN A 1 191 ? 38.936 3.528   11.971 1.00 6.27  ? 191 GLN A HB2  191 GLN A 1HB  1 
ATOM 2831 H HB3  . GLN A 1 191 ? 37.836 3.757   10.619 1.00 6.27  ? 191 GLN A HB3  191 GLN A 2HB  1 
ATOM 2832 H HG2  . GLN A 1 191 ? 37.203 5.334   12.232 1.00 6.27  ? 191 GLN A HG2  191 GLN A 1HG  1 
ATOM 2833 H HG3  . GLN A 1 191 ? 35.983 4.034   12.343 1.00 6.27  ? 191 GLN A HG3  191 GLN A 2HG  1 
ATOM 2834 H HE21 . GLN A 1 191 ? 36.484 3.530   15.726 1.00 6.27  ? 191 GLN A HE21 191 GLN A 1HE2 1 
ATOM 2835 H HE22 . GLN A 1 191 ? 35.470 3.408   14.326 1.00 6.27  ? 191 GLN A HE22 191 GLN A 2HE2 1 
ATOM 2836 N N    . LYS A 1 192 ? 35.455 1.178   12.731 1.00 6.52  ? 192 LYS A N    192 LYS A N    1 
ATOM 2837 C CA   . LYS A 1 192 ? 33.940 1.000   12.761 1.00 6.52  ? 192 LYS A CA   192 LYS A CA   1 
ATOM 2838 C C    . LYS A 1 192 ? 33.391 1.963   13.671 1.00 6.52  ? 192 LYS A C    192 LYS A C    1 
ATOM 2839 O O    . LYS A 1 192 ? 34.106 1.848   14.617 1.00 6.52  ? 192 LYS A O    192 LYS A O    1 
ATOM 2840 C CB   . LYS A 1 192 ? 33.497 -0.395  13.204 1.00 6.52  ? 192 LYS A CB   192 LYS A CB   1 
ATOM 2841 C CG   . LYS A 1 192 ? 33.840 -1.506  12.220 1.00 6.52  ? 192 LYS A CG   192 LYS A CG   1 
ATOM 2842 C CD   . LYS A 1 192 ? 33.300 -2.847  12.690 1.00 6.52  ? 192 LYS A CD   192 LYS A CD   1 
ATOM 2843 C CE   . LYS A 1 192 ? 33.644 -3.959  11.710 1.00 6.52  ? 192 LYS A CE   192 LYS A CE   1 
ATOM 2844 N NZ   . LYS A 1 192 ? 32.966 -3.775  10.399 1.00 6.52  ? 192 LYS A NZ   192 LYS A NZ   1 
ATOM 2845 H H    . LYS A 1 192 ? 36.013 1.068   13.551 1.00 6.52  ? 192 LYS A H    192 LYS A H    1 
ATOM 2846 H HA   . LYS A 1 192 ? 33.553 1.155   11.753 1.00 6.52  ? 192 LYS A HA   192 LYS A HA   1 
ATOM 2847 H HB2  . LYS A 1 192 ? 33.964 -0.638  14.159 1.00 6.52  ? 192 LYS A HB2  192 LYS A 1HB  1 
ATOM 2848 H HB3  . LYS A 1 192 ? 32.418 -0.404  13.355 1.00 6.52  ? 192 LYS A HB3  192 LYS A 2HB  1 
ATOM 2849 H HG2  . LYS A 1 192 ? 33.412 -1.273  11.244 1.00 6.52  ? 192 LYS A HG2  192 LYS A 1HG  1 
ATOM 2850 H HG3  . LYS A 1 192 ? 34.922 -1.577  12.114 1.00 6.52  ? 192 LYS A HG3  192 LYS A 2HG  1 
ATOM 2851 H HD2  . LYS A 1 192 ? 33.724 -3.089  13.666 1.00 6.52  ? 192 LYS A HD2  192 LYS A 1HD  1 
ATOM 2852 H HD3  . LYS A 1 192 ? 32.216 -2.788  12.791 1.00 6.52  ? 192 LYS A HD3  192 LYS A 2HD  1 
ATOM 2853 H HE2  . LYS A 1 192 ? 34.721 -3.980  11.548 1.00 6.52  ? 192 LYS A HE2  192 LYS A 1HE  1 
ATOM 2854 H HE3  . LYS A 1 192 ? 33.344 -4.919  12.129 1.00 6.52  ? 192 LYS A HE3  192 LYS A 2HE  1 
ATOM 2855 H HZ1  . LYS A 1 192 ? 33.219 -4.531  9.779  1.00 6.52  ? 192 LYS A HZ1  192 LYS A 1HZ  1 
ATOM 2856 H HZ2  . LYS A 1 192 ? 31.964 -3.773  10.535 1.00 6.52  ? 192 LYS A HZ2  192 LYS A 2HZ  1 
ATOM 2857 H HZ3  . LYS A 1 192 ? 33.251 -2.896  9.992  1.00 6.52  ? 192 LYS A HZ3  192 LYS A 3HZ  1 
ATOM 2858 N N    . PRO A 1 193 ? 32.143 2.571   13.505 1.00 6.90  ? 193 PRO A N    193 PRO A N    1 
ATOM 2859 C CA   . PRO A 1 193 ? 31.616 3.504   14.577 1.00 6.90  ? 193 PRO A CA   193 PRO A CA   1 
ATOM 2860 C C    . PRO A 1 193 ? 31.461 2.752   15.851 1.00 6.90  ? 193 PRO A C    193 PRO A C    1 
ATOM 2861 O O    . PRO A 1 193 ? 30.947 1.484   15.790 1.00 6.90  ? 193 PRO A O    193 PRO A O    1 
ATOM 2862 C CB   . PRO A 1 193 ? 30.257 3.976   14.051 1.00 6.90  ? 193 PRO A CB   193 PRO A CB   1 
ATOM 2863 C CG   . PRO A 1 193 ? 30.415 3.963   12.568 1.00 6.90  ? 193 PRO A CG   193 PRO A CG   1 
ATOM 2864 C CD   . PRO A 1 193 ? 31.246 2.739   12.291 1.00 6.90  ? 193 PRO A CD   193 PRO A CD   1 
ATOM 2865 H HA   . PRO A 1 193 ? 32.301 4.359   14.681 1.00 6.90  ? 193 PRO A HA   193 PRO A HA   1 
ATOM 2866 H HB2  . PRO A 1 193 ? 29.463 3.300   14.401 1.00 6.90  ? 193 PRO A HB2  193 PRO A 1HB  1 
ATOM 2867 H HB3  . PRO A 1 193 ? 30.026 4.976   14.447 1.00 6.90  ? 193 PRO A HB3  193 PRO A 2HB  1 
ATOM 2868 H HG2  . PRO A 1 193 ? 29.430 3.925   12.082 1.00 6.90  ? 193 PRO A HG2  193 PRO A 1HG  1 
ATOM 2869 H HG3  . PRO A 1 193 ? 30.901 4.891   12.230 1.00 6.90  ? 193 PRO A HG3  193 PRO A 2HG  1 
ATOM 2870 H HD2  . PRO A 1 193 ? 30.587 1.866   12.179 1.00 6.90  ? 193 PRO A HD2  193 PRO A 1HD  1 
ATOM 2871 H HD3  . PRO A 1 193 ? 31.840 2.897   11.378 1.00 6.90  ? 193 PRO A HD3  193 PRO A 2HD  1 
ATOM 2872 N N    . GLY A 1 194 ? 32.112 3.606   16.926 1.00 7.12  ? 194 GLY A N    194 GLY A N    1 
ATOM 2873 C CA   . GLY A 1 194 ? 32.222 3.398   18.407 1.00 7.12  ? 194 GLY A CA   194 GLY A CA   1 
ATOM 2874 C C    . GLY A 1 194 ? 33.260 2.395   18.755 1.00 7.12  ? 194 GLY A C    194 GLY A C    1 
ATOM 2875 O O    . GLY A 1 194 ? 33.570 2.358   20.085 1.00 7.12  ? 194 GLY A O    194 GLY A O    1 
ATOM 2876 H H    . GLY A 1 194 ? 32.555 4.457   16.633 1.00 7.12  ? 194 GLY A H    194 GLY A H    1 
ATOM 2877 H HA2  . GLY A 1 194 ? 32.462 4.345   18.891 1.00 7.12  ? 194 GLY A HA2  194 GLY A 1HA  1 
ATOM 2878 H HA3  . GLY A 1 194 ? 31.261 3.070   18.801 1.00 7.12  ? 194 GLY A HA3  194 GLY A 2HA  1 
ATOM 2879 N N    . GLN A 1 195 ? 33.936 1.757   17.547 1.00 6.84  ? 195 GLN A N    195 GLN A N    1 
ATOM 2880 C CA   . GLN A 1 195 ? 34.915 0.671   17.911 1.00 6.84  ? 195 GLN A CA   195 GLN A CA   1 
ATOM 2881 C C    . GLN A 1 195 ? 36.395 1.343   17.803 1.00 6.84  ? 195 GLN A C    195 GLN A C    1 
ATOM 2882 O O    . GLN A 1 195 ? 36.679 2.477   16.982 1.00 6.84  ? 195 GLN A O    195 GLN A O    1 
ATOM 2883 C CB   . GLN A 1 195 ? 34.768 -0.540  16.987 1.00 6.84  ? 195 GLN A CB   195 GLN A CB   1 
ATOM 2884 C CG   . GLN A 1 195 ? 33.357 -1.100  16.913 1.00 6.84  ? 195 GLN A CG   195 GLN A CG   1 
ATOM 2885 C CD   . GLN A 1 195 ? 32.852 -1.574  18.263 1.00 6.84  ? 195 GLN A CD   195 GLN A CD   1 
ATOM 2886 O OE1  . GLN A 1 195 ? 33.481 -2.408  18.919 1.00 6.84  ? 195 GLN A OE1  195 GLN A OE1  1 
ATOM 2887 N NE2  . GLN A 1 195 ? 31.710 -1.043  18.685 1.00 6.84  ? 195 GLN A NE2  195 GLN A NE2  1 
ATOM 2888 H H    . GLN A 1 195 ? 33.861 1.982   16.638 1.00 6.84  ? 195 GLN A H    195 GLN A H    1 
ATOM 2889 H HA   . GLN A 1 195 ? 34.710 0.349   18.932 1.00 6.84  ? 195 GLN A HA   195 GLN A HA   1 
ATOM 2890 H HB2  . GLN A 1 195 ? 35.074 -0.267  15.977 1.00 6.84  ? 195 GLN A HB2  195 GLN A 1HB  1 
ATOM 2891 H HB3  . GLN A 1 195 ? 35.429 -1.338  17.324 1.00 6.84  ? 195 GLN A HB3  195 GLN A 2HB  1 
ATOM 2892 H HG2  . GLN A 1 195 ? 32.687 -0.320  16.551 1.00 6.84  ? 195 GLN A HG2  195 GLN A 1HG  1 
ATOM 2893 H HG3  . GLN A 1 195 ? 33.349 -1.947  16.228 1.00 6.84  ? 195 GLN A HG3  195 GLN A 2HG  1 
ATOM 2894 H HE21 . GLN A 1 195 ? 31.327 -1.317  19.569 1.00 6.84  ? 195 GLN A HE21 195 GLN A 1HE2 1 
ATOM 2895 H HE22 . GLN A 1 195 ? 31.232 -0.369  18.122 1.00 6.84  ? 195 GLN A HE22 195 GLN A 2HE2 1 
ATOM 2896 N N    . PRO A 1 196 ? 37.295 0.558   18.703 1.00 6.77  ? 196 PRO A N    196 PRO A N    1 
ATOM 2897 C CA   . PRO A 1 196 ? 38.720 0.951   18.548 1.00 6.77  ? 196 PRO A CA   196 PRO A CA   1 
ATOM 2898 C C    . PRO A 1 196 ? 39.186 0.487   17.162 1.00 6.77  ? 196 PRO A C    196 PRO A C    1 
ATOM 2899 O O    . PRO A 1 196 ? 38.571 -0.676  16.727 1.00 6.77  ? 196 PRO A O    196 PRO A O    1 
ATOM 2900 C CB   . PRO A 1 196 ? 39.438 0.205   19.678 1.00 6.77  ? 196 PRO A CB   196 PRO A CB   1 
ATOM 2901 C CG   . PRO A 1 196 ? 38.623 -1.028  19.877 1.00 6.77  ? 196 PRO A CG   196 PRO A CG   1 
ATOM 2902 C CD   . PRO A 1 196 ? 37.201 -0.572  19.687 1.00 6.77  ? 196 PRO A CD   196 PRO A CD   1 
ATOM 2903 H HA   . PRO A 1 196 ? 38.812 2.038   18.686 1.00 6.77  ? 196 PRO A HA   196 PRO A HA   1 
ATOM 2904 H HB2  . PRO A 1 196 ? 40.476 -0.012  19.385 1.00 6.77  ? 196 PRO A HB2  196 PRO A 1HB  1 
ATOM 2905 H HB3  . PRO A 1 196 ? 39.483 0.836   20.577 1.00 6.77  ? 196 PRO A HB3  196 PRO A 2HB  1 
ATOM 2906 H HG2  . PRO A 1 196 ? 38.921 -1.801  19.153 1.00 6.77  ? 196 PRO A HG2  196 PRO A 1HG  1 
ATOM 2907 H HG3  . PRO A 1 196 ? 38.804 -1.444  20.879 1.00 6.77  ? 196 PRO A HG3  196 PRO A 2HG  1 
ATOM 2908 H HD2  . PRO A 1 196 ? 36.602 -1.399  19.280 1.00 6.77  ? 196 PRO A HD2  196 PRO A 1HD  1 
ATOM 2909 H HD3  . PRO A 1 196 ? 36.792 -0.233  20.650 1.00 6.77  ? 196 PRO A HD3  196 PRO A 2HD  1 
ATOM 2910 N N    . PRO A 1 197 ? 40.222 1.350   16.506 1.00 6.35  ? 197 PRO A N    197 PRO A N    1 
ATOM 2911 C CA   . PRO A 1 197 ? 40.714 0.681   15.231 1.00 6.35  ? 197 PRO A CA   197 PRO A CA   1 
ATOM 2912 C C    . PRO A 1 197 ? 41.287 -0.715  15.434 1.00 6.35  ? 197 PRO A C    197 PRO A C    1 
ATOM 2913 O O    . PRO A 1 197 ? 41.977 -0.798  16.520 1.00 6.35  ? 197 PRO A O    197 PRO A O    1 
ATOM 2914 C CB   . PRO A 1 197 ? 41.806 1.635   14.737 1.00 6.35  ? 197 PRO A CB   197 PRO A CB   1 
ATOM 2915 C CG   . PRO A 1 197 ? 41.443 2.949   15.339 1.00 6.35  ? 197 PRO A CG   197 PRO A CG   1 
ATOM 2916 C CD   . PRO A 1 197 ? 40.944 2.605   16.717 1.00 6.35  ? 197 PRO A CD   197 PRO A CD   1 
ATOM 2917 H HA   . PRO A 1 197 ? 39.886 0.624   14.510 1.00 6.35  ? 197 PRO A HA   197 PRO A HA   1 
ATOM 2918 H HB2  . PRO A 1 197 ? 42.794 1.275   15.061 1.00 6.35  ? 197 PRO A HB2  197 PRO A 1HB  1 
ATOM 2919 H HB3  . PRO A 1 197 ? 41.816 1.657   13.637 1.00 6.35  ? 197 PRO A HB3  197 PRO A 2HB  1 
ATOM 2920 H HG2  . PRO A 1 197 ? 42.320 3.612   15.360 1.00 6.35  ? 197 PRO A HG2  197 PRO A 1HG  1 
ATOM 2921 H HG3  . PRO A 1 197 ? 40.680 3.450   14.725 1.00 6.35  ? 197 PRO A HG3  197 PRO A 2HG  1 
ATOM 2922 H HD2  . PRO A 1 197 ? 41.800 2.479   17.397 1.00 6.35  ? 197 PRO A HD2  197 PRO A 1HD  1 
ATOM 2923 H HD3  . PRO A 1 197 ? 40.277 3.402   17.076 1.00 6.35  ? 197 PRO A HD3  197 PRO A 2HD  1 
ATOM 2924 N N    . LYS A 1 198 ? 40.863 -1.718  14.329 1.00 6.21  ? 198 LYS A N    198 LYS A N    1 
ATOM 2925 C CA   . LYS A 1 198 ? 41.262 -3.030  14.311 1.00 6.21  ? 198 LYS A CA   198 LYS A CA   1 
ATOM 2926 C C    . LYS A 1 198 ? 42.414 -3.130  13.387 1.00 6.21  ? 198 LYS A C    198 LYS A C    1 
ATOM 2927 O O    . LYS A 1 198 ? 42.234 -2.592  12.170 1.00 6.21  ? 198 LYS A O    198 LYS A O    1 
ATOM 2928 C CB   . LYS A 1 198 ? 40.112 -3.944  13.885 1.00 6.21  ? 198 LYS A CB   198 LYS A CB   1 
ATOM 2929 C CG   . LYS A 1 198 ? 40.460 -5.427  13.867 1.00 6.21  ? 198 LYS A CG   198 LYS A CG   1 
ATOM 2930 C CD   . LYS A 1 198 ? 39.266 -6.270  13.446 1.00 6.21  ? 198 LYS A CD   198 LYS A CD   1 
ATOM 2931 C CE   . LYS A 1 198 ? 39.629 -7.746  13.371 1.00 6.21  ? 198 LYS A CE   198 LYS A CE   1 
ATOM 2932 N NZ   . LYS A 1 198 ? 38.470 -8.583  12.958 1.00 6.21  ? 198 LYS A NZ   198 LYS A NZ   1 
ATOM 2933 H H    . LYS A 1 198 ? 40.407 -1.353  13.598 1.00 6.21  ? 198 LYS A H    198 LYS A H    1 
ATOM 2934 H HA   . LYS A 1 198 ? 41.571 -3.312  15.319 1.00 6.21  ? 198 LYS A HA   198 LYS A HA   1 
ATOM 2935 H HB2  . LYS A 1 198 ? 39.268 -3.807  14.560 1.00 6.21  ? 198 LYS A HB2  198 LYS A 1HB  1 
ATOM 2936 H HB3  . LYS A 1 198 ? 39.779 -3.667  12.884 1.00 6.21  ? 198 LYS A HB3  198 LYS A 2HB  1 
ATOM 2937 H HG2  . LYS A 1 198 ? 41.281 -5.600  13.170 1.00 6.21  ? 198 LYS A HG2  198 LYS A 1HG  1 
ATOM 2938 H HG3  . LYS A 1 198 ? 40.781 -5.736  14.861 1.00 6.21  ? 198 LYS A HG3  198 LYS A 2HG  1 
ATOM 2939 H HD2  . LYS A 1 198 ? 38.456 -6.139  14.166 1.00 6.21  ? 198 LYS A HD2  198 LYS A 1HD  1 
ATOM 2940 H HD3  . LYS A 1 198 ? 38.915 -5.941  12.468 1.00 6.21  ? 198 LYS A HD3  198 LYS A 2HD  1 
ATOM 2941 H HE2  . LYS A 1 198 ? 40.436 -7.885  12.653 1.00 6.21  ? 198 LYS A HE2  198 LYS A 1HE  1 
ATOM 2942 H HE3  . LYS A 1 198 ? 39.976 -8.085  14.346 1.00 6.21  ? 198 LYS A HE3  198 LYS A 2HE  1 
ATOM 2943 H HZ1  . LYS A 1 198 ? 38.751 -9.553  12.920 1.00 6.21  ? 198 LYS A HZ1  198 LYS A 1HZ  1 
ATOM 2944 H HZ2  . LYS A 1 198 ? 37.720 -8.476  13.627 1.00 6.21  ? 198 LYS A HZ2  198 LYS A 2HZ  1 
ATOM 2945 H HZ3  . LYS A 1 198 ? 38.150 -8.290  12.046 1.00 6.21  ? 198 LYS A HZ3  198 LYS A 3HZ  1 
ATOM 2946 N N    . LEU A 1 199 ? 43.685 -3.710  13.965 1.00 5.99  ? 199 LEU A N    199 LEU A N    1 
ATOM 2947 C CA   . LEU A 1 199 ? 44.758 -4.008  12.958 1.00 5.99  ? 199 LEU A CA   199 LEU A CA   1 
ATOM 2948 C C    . LEU A 1 199 ? 44.391 -5.240  12.275 1.00 5.99  ? 199 LEU A C    199 LEU A C    1 
ATOM 2949 O O    . LEU A 1 199 ? 44.111 -6.114  13.163 1.00 5.99  ? 199 LEU A O    199 LEU A O    1 
ATOM 2950 C CB   . LEU A 1 199 ? 46.139 -4.184  13.601 1.00 5.99  ? 199 LEU A CB   199 LEU A CB   1 
ATOM 2951 C CG   . LEU A 1 199 ? 47.256 -4.652  12.659 1.00 5.99  ? 199 LEU A CG   199 LEU A CG   1 
ATOM 2952 C CD1  . LEU A 1 199 ? 47.634 -3.517  11.716 1.00 5.99  ? 199 LEU A CD1  199 LEU A CD1  1 
ATOM 2953 C CD2  . LEU A 1 199 ? 48.455 -5.105  13.478 1.00 5.99  ? 199 LEU A CD2  199 LEU A CD2  1 
ATOM 2954 H H    . LEU A 1 199 ? 43.720 -4.018  14.935 1.00 5.99  ? 199 LEU A H    199 LEU A H    1 
ATOM 2955 H HA   . LEU A 1 199 ? 44.822 -3.172  12.264 1.00 5.99  ? 199 LEU A HA   199 LEU A HA   1 
ATOM 2956 H HB2  . LEU A 1 199 ? 46.446 -3.233  14.031 1.00 5.99  ? 199 LEU A HB2  199 LEU A 1HB  1 
ATOM 2957 H HB3  . LEU A 1 199 ? 46.058 -4.914  14.406 1.00 5.99  ? 199 LEU A HB3  199 LEU A 2HB  1 
ATOM 2958 H HG   . LEU A 1 199 ? 46.896 -5.483  12.052 1.00 5.99  ? 199 LEU A HG   199 LEU A HG   1 
ATOM 2959 H HD11 . LEU A 1 199 ? 48.428 -3.850  11.047 1.00 5.99  ? 199 LEU A HD11 199 LEU A 1HD1 1 
ATOM 2960 H HD12 . LEU A 1 199 ? 46.763 -3.227  11.129 1.00 5.99  ? 199 LEU A HD12 199 LEU A 2HD1 1 
ATOM 2961 H HD13 . LEU A 1 199 ? 47.983 -2.664  12.296 1.00 5.99  ? 199 LEU A HD13 199 LEU A 3HD1 1 
ATOM 2962 H HD21 . LEU A 1 199 ? 49.249 -5.438  12.808 1.00 5.99  ? 199 LEU A HD21 199 LEU A 1HD2 1 
ATOM 2963 H HD22 . LEU A 1 199 ? 48.817 -4.274  14.084 1.00 5.99  ? 199 LEU A HD22 199 LEU A 2HD2 1 
ATOM 2964 H HD23 . LEU A 1 199 ? 48.161 -5.928  14.130 1.00 5.99  ? 199 LEU A HD23 199 LEU A 3HD2 1 
ATOM 2965 N N    . LEU A 1 200 ? 44.309 -5.158  10.737 1.00 5.88  ? 200 LEU A N    200 LEU A N    1 
ATOM 2966 C CA   . LEU A 1 200 ? 43.879 -6.091  9.820  1.00 5.88  ? 200 LEU A CA   200 LEU A CA   1 
ATOM 2967 C C    . LEU A 1 200 ? 45.087 -6.758  9.266  1.00 5.88  ? 200 LEU A C    200 LEU A C    1 
ATOM 2968 O O    . LEU A 1 200 ? 45.252 -7.998  9.635  1.00 5.88  ? 200 LEU A O    200 LEU A O    1 
ATOM 2969 C CB   . LEU A 1 200 ? 43.054 -5.420  8.714  1.00 5.88  ? 200 LEU A CB   200 LEU A CB   1 
ATOM 2970 C CG   . LEU A 1 200 ? 41.627 -5.014  9.101  1.00 5.88  ? 200 LEU A CG   200 LEU A CG   1 
ATOM 2971 C CD1  . LEU A 1 200 ? 40.825 -4.712  7.843  1.00 5.88  ? 200 LEU A CD1  200 LEU A CD1  1 
ATOM 2972 C CD2  . LEU A 1 200 ? 40.981 -6.131  9.907  1.00 5.88  ? 200 LEU A CD2  200 LEU A CD2  1 
ATOM 2973 H H    . LEU A 1 200 ? 44.774 -4.435  10.383 1.00 5.88  ? 200 LEU A H    200 LEU A H    1 
ATOM 2974 H HA   . LEU A 1 200 ? 43.247 -6.815  10.333 1.00 5.88  ? 200 LEU A HA   200 LEU A HA   1 
ATOM 2975 H HB2  . LEU A 1 200 ? 43.577 -4.523  8.387  1.00 5.88  ? 200 LEU A HB2  200 LEU A 1HB  1 
ATOM 2976 H HB3  . LEU A 1 200 ? 42.986 -6.104  7.868  1.00 5.88  ? 200 LEU A HB3  200 LEU A 2HB  1 
ATOM 2977 H HG   . LEU A 1 200 ? 41.658 -4.105  9.702  1.00 5.88  ? 200 LEU A HG   200 LEU A HG   1 
ATOM 2978 H HD11 . LEU A 1 200 ? 39.811 -4.423  8.118  1.00 5.88  ? 200 LEU A HD11 200 LEU A 1HD1 1 
ATOM 2979 H HD12 . LEU A 1 200 ? 41.298 -3.896  7.296  1.00 5.88  ? 200 LEU A HD12 200 LEU A 2HD1 1 
ATOM 2980 H HD13 . LEU A 1 200 ? 40.790 -5.600  7.212  1.00 5.88  ? 200 LEU A HD13 200 LEU A 3HD1 1 
ATOM 2981 H HD21 . LEU A 1 200 ? 39.967 -5.842  10.183 1.00 5.88  ? 200 LEU A HD21 200 LEU A 1HD2 1 
ATOM 2982 H HD22 . LEU A 1 200 ? 40.948 -7.041  9.306  1.00 5.88  ? 200 LEU A HD22 200 LEU A 2HD2 1 
ATOM 2983 H HD23 . LEU A 1 200 ? 41.565 -6.314  10.809 1.00 5.88  ? 200 LEU A HD23 200 LEU A 3HD2 1 
ATOM 2984 N N    . ILE A 1 201 ? 46.000 -5.855  8.517  1.00 5.68  ? 201 ILE A N    201 ILE A N    1 
ATOM 2985 C CA   . ILE A 1 201 ? 47.286 -6.436  8.004  1.00 5.68  ? 201 ILE A CA   201 ILE A CA   1 
ATOM 2986 C C    . ILE A 1 201 ? 48.413 -5.552  8.379  1.00 5.68  ? 201 ILE A C    201 ILE A C    1 
ATOM 2987 O O    . ILE A 1 201 ? 47.898 -4.397  8.267  1.00 5.68  ? 201 ILE A O    201 ILE A O    1 
ATOM 2988 C CB   . ILE A 1 201 ? 47.287 -6.612  6.474  1.00 5.68  ? 201 ILE A CB   201 ILE A CB   1 
ATOM 2989 C CG1  . ILE A 1 201 ? 48.532 -7.383  6.026  1.00 5.68  ? 201 ILE A CG1  201 ILE A CG1  1 
ATOM 2990 C CG2  . ILE A 1 201 ? 47.217 -5.259  5.783  1.00 5.68  ? 201 ILE A CG2  201 ILE A CG2  1 
ATOM 2991 C CD1  . ILE A 1 201 ? 48.465 -7.873  4.598  1.00 5.68  ? 201 ILE A CD1  201 ILE A CD1  1 
ATOM 2992 H H    . ILE A 1 201 ? 45.750 -4.889  8.425  1.00 5.68  ? 201 ILE A H    201 ILE A H    1 
ATOM 2993 H HA   . ILE A 1 201 ? 47.422 -7.421  8.449  1.00 5.68  ? 201 ILE A HA   201 ILE A HA   1 
ATOM 2994 H HB   . ILE A 1 201 ? 46.424 -7.207  6.176  1.00 5.68  ? 201 ILE A HB   201 ILE A HB   1 
ATOM 2995 H HG12 . ILE A 1 201 ? 49.410 -6.746  6.128  1.00 5.68  ? 201 ILE A HG12 201 ILE A 1HG1 1 
ATOM 2996 H HG13 . ILE A 1 201 ? 48.678 -8.246  6.676  1.00 5.68  ? 201 ILE A HG13 201 ILE A 2HG1 1 
ATOM 2997 H HG21 . ILE A 1 201 ? 47.220 -5.402  4.703  1.00 5.68  ? 201 ILE A HG21 201 ILE A 1HG2 1 
ATOM 2998 H HG22 . ILE A 1 201 ? 46.303 -4.746  6.079  1.00 5.68  ? 201 ILE A HG22 201 ILE A 2HG2 1 
ATOM 2999 H HG23 . ILE A 1 201 ? 48.080 -4.658  6.071  1.00 5.68  ? 201 ILE A HG23 201 ILE A 3HG2 1 
ATOM 3000 H HD11 . ILE A 1 201 ? 49.382 -8.410  4.354  1.00 5.68  ? 201 ILE A HD11 201 ILE A 1HD1 1 
ATOM 3001 H HD12 . ILE A 1 201 ? 47.611 -8.542  4.483  1.00 5.68  ? 201 ILE A HD12 201 ILE A 2HD1 1 
ATOM 3002 H HD13 . ILE A 1 201 ? 48.353 -7.023  3.926  1.00 5.68  ? 201 ILE A HD13 201 ILE A 3HD1 1 
ATOM 3003 N N    . TYR A 1 202 ? 49.725 -6.085  8.855  1.00 5.49  ? 202 TYR A N    202 TYR A N    1 
ATOM 3004 C CA   . TYR A 1 202 ? 50.830 -5.342  9.178  1.00 5.49  ? 202 TYR A CA   202 TYR A CA   1 
ATOM 3005 C C    . TYR A 1 202 ? 51.836 -5.948  8.428  1.00 5.49  ? 202 TYR A C    202 TYR A C    1 
ATOM 3006 O O    . TYR A 1 202 ? 51.907 -7.185  8.850  1.00 5.49  ? 202 TYR A O    202 TYR A O    1 
ATOM 3007 C CB   . TYR A 1 202 ? 51.150 -5.349  10.674 1.00 5.49  ? 202 TYR A CB   202 TYR A CB   1 
ATOM 3008 C CG   . TYR A 1 202 ? 52.501 -4.759  11.012 1.00 5.49  ? 202 TYR A CG   202 TYR A CG   1 
ATOM 3009 C CD1  . TYR A 1 202 ? 52.699 -3.388  10.931 1.00 5.49  ? 202 TYR A CD1  202 TYR A CD1  1 
ATOM 3010 C CD2  . TYR A 1 202 ? 53.541 -5.588  11.403 1.00 5.49  ? 202 TYR A CD2  202 TYR A CD2  1 
ATOM 3011 C CE1  . TYR A 1 202 ? 53.933 -2.849  11.240 1.00 5.49  ? 202 TYR A CE1  202 TYR A CE1  1 
ATOM 3012 C CE2  . TYR A 1 202 ? 54.775 -5.049  11.711 1.00 5.49  ? 202 TYR A CE2  202 TYR A CE2  1 
ATOM 3013 C CZ   . TYR A 1 202 ? 54.973 -3.686  11.631 1.00 5.49  ? 202 TYR A CZ   202 TYR A CZ   1 
ATOM 3014 O OH   . TYR A 1 202 ? 56.202 -3.149  11.938 1.00 5.49  ? 202 TYR A OH   202 TYR A OH   1 
ATOM 3015 H H    . TYR A 1 202 ? 49.895 -7.028  8.890  1.00 5.49  ? 202 TYR A H    202 TYR A H    1 
ATOM 3016 H HA   . TYR A 1 202 ? 50.645 -4.306  8.891  1.00 5.49  ? 202 TYR A HA   202 TYR A HA   1 
ATOM 3017 H HB2  . TYR A 1 202 ? 50.387 -4.783  11.212 1.00 5.49  ? 202 TYR A HB2  202 TYR A 1HB  1 
ATOM 3018 H HB3  . TYR A 1 202 ? 51.122 -6.372  11.047 1.00 5.49  ? 202 TYR A HB3  202 TYR A 2HB  1 
ATOM 3019 H HD1  . TYR A 1 202 ? 51.881 -2.736  10.624 1.00 5.49  ? 202 TYR A HD1  202 TYR A HD1  1 
ATOM 3020 H HD2  . TYR A 1 202 ? 53.386 -6.665  11.465 1.00 5.49  ? 202 TYR A HD2  202 TYR A HD2  1 
ATOM 3021 H HE1  . TYR A 1 202 ? 54.089 -1.773  11.176 1.00 5.49  ? 202 TYR A HE1  202 TYR A HE1  1 
ATOM 3022 H HE2  . TYR A 1 202 ? 55.594 -5.701  12.018 1.00 5.49  ? 202 TYR A HE2  202 TYR A HE2  1 
ATOM 3023 H HH   . TYR A 1 202 ? 56.818 -3.858  12.138 1.00 5.49  ? 202 TYR A HH   202 TYR A HH   1 
ATOM 3024 N N    . TRP A 1 203 ? 52.663 -5.107  7.424  1.00 5.18  ? 203 TRP A N    203 TRP A N    1 
ATOM 3025 C CA   . TRP A 1 203 ? 53.710 -5.437  6.574  1.00 5.18  ? 203 TRP A CA   203 TRP A CA   1 
ATOM 3026 C C    . TRP A 1 203 ? 55.040 -5.114  7.205  1.00 5.18  ? 203 TRP A C    203 TRP A C    1 
ATOM 3027 O O    . TRP A 1 203 ? 55.109 -3.853  7.689  1.00 5.18  ? 203 TRP A O    203 TRP A O    1 
ATOM 3028 C CB   . TRP A 1 203 ? 53.550 -4.689  5.248  1.00 5.18  ? 203 TRP A CB   203 TRP A CB   1 
ATOM 3029 C CG   . TRP A 1 203 ? 54.743 -4.805  4.349  1.00 5.18  ? 203 TRP A CG   203 TRP A CG   1 
ATOM 3030 C CD1  . TRP A 1 203 ? 55.746 -3.894  4.205  1.00 5.18  ? 203 TRP A CD1  203 TRP A CD1  1 
ATOM 3031 C CD2  . TRP A 1 203 ? 55.066 -5.901  3.459  1.00 5.18  ? 203 TRP A CD2  203 TRP A CD2  1 
ATOM 3032 N NE1  . TRP A 1 203 ? 56.666 -4.344  3.290  1.00 5.18  ? 203 TRP A NE1  203 TRP A NE1  1 
ATOM 3033 C CE2  . TRP A 1 203 ? 56.267 -5.571  2.825  1.00 5.18  ? 203 TRP A CE2  203 TRP A CE2  1 
ATOM 3034 C CE3  . TRP A 1 203 ? 54.441 -7.117  3.155  1.00 5.18  ? 203 TRP A CE3  203 TRP A CE3  1 
ATOM 3035 C CZ2  . TRP A 1 203 ? 56.862 -6.413  1.899  1.00 5.18  ? 203 TRP A CZ2  203 TRP A CZ2  1 
ATOM 3036 C CZ3  . TRP A 1 203 ? 55.039 -7.961  2.227  1.00 5.18  ? 203 TRP A CZ3  203 TRP A CZ3  1 
ATOM 3037 C CH2  . TRP A 1 203 ? 56.219 -7.618  1.616  1.00 5.18  ? 203 TRP A CH2  203 TRP A CH2  1 
ATOM 3038 H H    . TRP A 1 203 ? 53.119 -5.985  7.608  1.00 5.18  ? 203 TRP A H    203 TRP A H    1 
ATOM 3039 H HA   . TRP A 1 203 ? 53.676 -6.509  6.384  1.00 5.18  ? 203 TRP A HA   203 TRP A HA   1 
ATOM 3040 H HB2  . TRP A 1 203 ? 52.680 -5.075  4.716  1.00 5.18  ? 203 TRP A HB2  203 TRP A 1HB  1 
ATOM 3041 H HB3  . TRP A 1 203 ? 53.370 -3.633  5.446  1.00 5.18  ? 203 TRP A HB3  203 TRP A 2HB  1 
ATOM 3042 H HD1  . TRP A 1 203 ? 55.809 -2.947  4.738  1.00 5.18  ? 203 TRP A HD1  203 TRP A HD1  1 
ATOM 3043 H HE1  . TRP A 1 203 ? 57.501 -3.853  3.005  1.00 5.18  ? 203 TRP A HE1  203 TRP A HE1  1 
ATOM 3044 H HE3  . TRP A 1 203 ? 53.506 -7.396  3.640  1.00 5.18  ? 203 TRP A HE3  203 TRP A HE3  1 
ATOM 3045 H HZ2  . TRP A 1 203 ? 57.799 -6.158  1.402  1.00 5.18  ? 203 TRP A HZ2  203 TRP A HZ2  1 
ATOM 3046 H HZ3  . TRP A 1 203 ? 54.546 -8.906  1.996  1.00 5.18  ? 203 TRP A HZ3  203 TRP A HZ3  1 
ATOM 3047 H HH2  . TRP A 1 203 ? 56.661 -8.304  0.893  1.00 5.18  ? 203 TRP A HH2  203 TRP A HH2  1 
ATOM 3048 N N    . ALA A 1 204 ? 55.978 -6.349  7.346  1.00 5.24  ? 204 ALA A N    204 ALA A N    1 
ATOM 3049 C CA   . ALA A 1 204 ? 57.258 -6.185  7.957  1.00 5.24  ? 204 ALA A CA   204 ALA A CA   1 
ATOM 3050 C C    . ALA A 1 204 ? 57.093 -6.972  6.550  1.00 5.24  ? 204 ALA A C    204 ALA A C    1 
ATOM 3051 O O    . ALA A 1 204 ? 55.818 -7.528  6.197  1.00 5.24  ? 204 ALA A O    204 ALA A O    1 
ATOM 3052 C CB   . ALA A 1 204 ? 57.641 -6.892  9.249  1.00 5.24  ? 204 ALA A CB   204 ALA A CB   1 
ATOM 3053 H H    . ALA A 1 204 ? 55.753 -7.262  6.983  1.00 5.24  ? 204 ALA A H    204 ALA A H    1 
ATOM 3054 H HA   . ALA A 1 204 ? 57.381 -5.132  8.211  1.00 5.24  ? 204 ALA A HA   204 ALA A HA   1 
ATOM 3055 H 1HB  . ALA A 1 204 ? 58.723 -7.011  9.293  1.00 5.24  ? 204 ALA A 1HB  204 ALA A 1HB  1 
ATOM 3056 H 2HB  . ALA A 1 204 ? 57.307 -6.300  10.101 1.00 5.24  ? 204 ALA A 2HB  204 ALA A 2HB  1 
ATOM 3057 H 3HB  . ALA A 1 204 ? 57.167 -7.872  9.282  1.00 5.24  ? 204 ALA A 3HB  204 ALA A 3HB  1 
ATOM 3058 N N    . SER A 1 205 ? 58.416 -7.240  6.063  1.00 5.75  ? 205 SER A N    205 SER A N    1 
ATOM 3059 C CA   . SER A 1 205 ? 58.860 -7.770  4.800  1.00 5.75  ? 205 SER A CA   205 SER A CA   1 
ATOM 3060 C C    . SER A 1 205 ? 58.481 -9.318  4.506  1.00 5.75  ? 205 SER A C    205 SER A C    1 
ATOM 3061 O O    . SER A 1 205 ? 58.332 -9.668  3.164  1.00 5.75  ? 205 SER A O    205 SER A O    1 
ATOM 3062 C CB   . SER A 1 205 ? 60.363 -7.574  4.742  1.00 5.75  ? 205 SER A CB   205 SER A CB   1 
ATOM 3063 O OG   . SER A 1 205 ? 61.010 -8.368  5.698  1.00 5.75  ? 205 SER A OG   205 SER A OG   1 
ATOM 3064 H H    . SER A 1 205 ? 59.190 -6.979  6.668  1.00 5.75  ? 205 SER A H    205 SER A H    1 
ATOM 3065 H HA   . SER A 1 205 ? 58.374 -7.211  3.999  1.00 5.75  ? 205 SER A HA   205 SER A HA   1 
ATOM 3066 H HB2  . SER A 1 205 ? 60.726 -7.829  3.747  1.00 5.75  ? 205 SER A HB2  205 SER A 1HB  1 
ATOM 3067 H HB3  . SER A 1 205 ? 60.599 -6.525  4.917  1.00 5.75  ? 205 SER A HB3  205 SER A 2HB  1 
ATOM 3068 H HG   . SER A 1 205 ? 60.572 -9.222  5.672  1.00 5.75  ? 205 SER A HG   205 SER A HG   1 
ATOM 3069 N N    . THR A 1 206 ? 57.970 -10.089 5.760  1.00 6.32  ? 206 THR A N    206 THR A N    1 
ATOM 3070 C CA   . THR A 1 206 ? 57.808 -11.455 5.365  1.00 6.32  ? 206 THR A CA   206 THR A CA   1 
ATOM 3071 C C    . THR A 1 206 ? 56.332 -11.506 5.813  1.00 6.32  ? 206 THR A C    206 THR A C    1 
ATOM 3072 O O    . THR A 1 206 ? 56.124 -10.940 7.007  1.00 6.32  ? 206 THR A O    206 THR A O    1 
ATOM 3073 C CB   . THR A 1 206 ? 58.728 -12.463 6.078  1.00 6.32  ? 206 THR A CB   206 THR A CB   1 
ATOM 3074 O OG1  . THR A 1 206 ? 60.098 -12.131 5.817  1.00 6.32  ? 206 THR A OG1  206 THR A OG1  1 
ATOM 3075 C CG2  . THR A 1 206 ? 58.451 -13.876 5.589  1.00 6.32  ? 206 THR A CG2  206 THR A CG2  1 
ATOM 3076 H H    . THR A 1 206 ? 57.843 -9.775  6.659  1.00 6.32  ? 206 THR A H    206 THR A H    1 
ATOM 3077 H HA   . THR A 1 206 ? 58.033 -11.537 4.302  1.00 6.32  ? 206 THR A HA   206 THR A HA   1 
ATOM 3078 H HB   . THR A 1 206 ? 58.556 -12.416 7.153  1.00 6.32  ? 206 THR A HB   206 THR A HB   1 
ATOM 3079 H HG1  . THR A 1 206 ? 60.608 -12.938 5.713  1.00 6.32  ? 206 THR A HG1  206 THR A HG1  1 
ATOM 3080 H HG21 . THR A 1 206 ? 59.110 -14.575 6.104  1.00 6.32  ? 206 THR A HG21 206 THR A 1HG2 1 
ATOM 3081 H HG22 . THR A 1 206 ? 57.413 -14.136 5.797  1.00 6.32  ? 206 THR A HG22 206 THR A 2HG2 1 
ATOM 3082 H HG23 . THR A 1 206 ? 58.631 -13.932 4.517  1.00 6.32  ? 206 THR A HG23 206 THR A 3HG2 1 
ATOM 3083 N N    . ARG A 1 207 ? 55.291 -12.192 4.845  1.00 6.50  ? 207 ARG A N    207 ARG A N    1 
ATOM 3084 C CA   . ARG A 1 207 ? 54.023 -12.279 5.550  1.00 6.50  ? 207 ARG A CA   207 ARG A CA   1 
ATOM 3085 C C    . ARG A 1 207 ? 53.960 -12.964 6.918  1.00 6.50  ? 207 ARG A C    207 ARG A C    1 
ATOM 3086 O O    . ARG A 1 207 ? 53.893 -14.275 7.007  1.00 6.50  ? 207 ARG A O    207 ARG A O    1 
ATOM 3087 C CB   . ARG A 1 207 ? 53.029 -12.985 4.640  1.00 6.50  ? 207 ARG A CB   207 ARG A CB   1 
ATOM 3088 C CG   . ARG A 1 207 ? 51.624 -13.117 5.207  1.00 6.50  ? 207 ARG A CG   207 ARG A CG   1 
ATOM 3089 C CD   . ARG A 1 207 ? 50.757 -13.954 4.339  1.00 6.50  ? 207 ARG A CD   207 ARG A CD   1 
ATOM 3090 N NE   . ARG A 1 207 ? 49.452 -14.185 4.937  1.00 6.50  ? 207 ARG A NE   207 ARG A NE   1 
ATOM 3091 C CZ   . ARG A 1 207 ? 48.356 -13.439 4.694  1.00 6.50  ? 207 ARG A CZ   207 ARG A CZ   1 
ATOM 3092 N NH1  . ARG A 1 207 ? 48.425 -12.421 3.866  1.00 6.50  ? 207 ARG A NH1  207 ARG A NH1  1 
ATOM 3093 N NH2  . ARG A 1 207 ? 47.213 -13.732 5.289  1.00 6.50  ? 207 ARG A NH2  207 ARG A NH2  1 
ATOM 3094 H H    . ARG A 1 207 ? 55.476 -12.460 3.861  1.00 6.50  ? 207 ARG A H    207 ARG A H    1 
ATOM 3095 H HA   . ARG A 1 207 ? 53.676 -11.268 5.764  1.00 6.50  ? 207 ARG A HA   207 ARG A HA   1 
ATOM 3096 H HB2  . ARG A 1 207 ? 52.954 -12.448 3.696  1.00 6.50  ? 207 ARG A HB2  207 ARG A 1HB  1 
ATOM 3097 H HB3  . ARG A 1 207 ? 53.390 -13.990 4.417  1.00 6.50  ? 207 ARG A HB3  207 ARG A 2HB  1 
ATOM 3098 H HG2  . ARG A 1 207 ? 51.671 -13.580 6.193  1.00 6.50  ? 207 ARG A HG2  207 ARG A 1HG  1 
ATOM 3099 H HG3  . ARG A 1 207 ? 51.172 -12.128 5.292  1.00 6.50  ? 207 ARG A HG3  207 ARG A 2HG  1 
ATOM 3100 H HD2  . ARG A 1 207 ? 50.610 -13.454 3.382  1.00 6.50  ? 207 ARG A HD2  207 ARG A 1HD  1 
ATOM 3101 H HD3  . ARG A 1 207 ? 51.232 -14.920 4.173  1.00 6.50  ? 207 ARG A HD3  207 ARG A 2HD  1 
ATOM 3102 H HE   . ARG A 1 207 ? 49.360 -14.960 5.580  1.00 6.50  ? 207 ARG A HE   207 ARG A HE   1 
ATOM 3103 H HH11 . ARG A 1 207 ? 49.298 -12.197 3.411  1.00 6.50  ? 207 ARG A HH11 207 ARG A 1HH1 1 
ATOM 3104 H HH12 . ARG A 1 207 ? 47.603 -11.862 3.684  1.00 6.50  ? 207 ARG A HH12 207 ARG A 2HH1 1 
ATOM 3105 H HH21 . ARG A 1 207 ? 47.161 -14.515 5.926  1.00 6.50  ? 207 ARG A HH21 207 ARG A 1HH2 1 
ATOM 3106 H HH22 . ARG A 1 207 ? 46.393 -13.173 5.108  1.00 6.50  ? 207 ARG A HH22 207 ARG A 2HH2 1 
ATOM 3107 N N    . GLU A 1 208 ? 53.437 -11.816 7.905  1.00 6.77  ? 208 GLU A N    208 GLU A N    1 
ATOM 3108 C CA   . GLU A 1 208 ? 53.180 -12.037 9.330  1.00 6.77  ? 208 GLU A CA   208 GLU A CA   1 
ATOM 3109 C C    . GLU A 1 208 ? 52.052 -13.046 9.489  1.00 6.77  ? 208 GLU A C    208 GLU A C    1 
ATOM 3110 O O    . GLU A 1 208 ? 50.953 -12.891 8.721  1.00 6.77  ? 208 GLU A O    208 GLU A O    1 
ATOM 3111 C CB   . GLU A 1 208 ? 52.821 -10.727 10.034 1.00 6.77  ? 208 GLU A CB   208 GLU A CB   1 
ATOM 3112 C CG   . GLU A 1 208 ? 53.956 -9.714  10.094 1.00 6.77  ? 208 GLU A CG   208 GLU A CG   1 
ATOM 3113 C CD   . GLU A 1 208 ? 55.008 -10.074 11.106 1.00 6.77  ? 208 GLU A CD   208 GLU A CD   1 
ATOM 3114 O OE1  . GLU A 1 208 ? 54.675 -10.206 12.260 1.00 6.77  ? 208 GLU A OE1  208 GLU A OE1  1 
ATOM 3115 O OE2  . GLU A 1 208 ? 56.146 -10.217 10.725 1.00 6.77  ? 208 GLU A OE2  208 GLU A OE2  1 
ATOM 3116 H H    . GLU A 1 208 ? 54.063 -11.112 7.686  1.00 6.77  ? 208 GLU A H    208 GLU A H    1 
ATOM 3117 H HA   . GLU A 1 208 ? 54.087 -12.436 9.787  1.00 6.77  ? 208 GLU A HA   208 GLU A HA   1 
ATOM 3118 H HB2  . GLU A 1 208 ? 51.981 -10.258 9.522  1.00 6.77  ? 208 GLU A HB2  208 GLU A 1HB  1 
ATOM 3119 H HB3  . GLU A 1 208 ? 52.506 -10.937 11.056 1.00 6.77  ? 208 GLU A HB3  208 GLU A 2HB  1 
ATOM 3120 H HG2  . GLU A 1 208 ? 54.422 -9.647  9.111  1.00 6.77  ? 208 GLU A HG2  208 GLU A 1HG  1 
ATOM 3121 H HG3  . GLU A 1 208 ? 53.543 -8.736  10.338 1.00 6.77  ? 208 GLU A HG3  208 GLU A 2HG  1 
ATOM 3122 N N    . SER A 1 209 ? 52.404 -14.013 10.604 1.00 7.42  ? 209 SER A N    209 SER A N    1 
ATOM 3123 C CA   . SER A 1 209 ? 51.585 -15.180 10.933 1.00 7.42  ? 209 SER A CA   209 SER A CA   1 
ATOM 3124 C C    . SER A 1 209 ? 50.666 -14.029 11.534 1.00 7.42  ? 209 SER A C    209 SER A C    1 
ATOM 3125 O O    . SER A 1 209 ? 51.235 -12.763 11.777 1.00 7.42  ? 209 SER A O    209 SER A O    1 
ATOM 3126 C CB   . SER A 1 209 ? 52.164 -16.192 11.901 1.00 7.42  ? 209 SER A CB   209 SER A CB   1 
ATOM 3127 O OG   . SER A 1 209 ? 52.319 -15.635 13.177 1.00 7.42  ? 209 SER A OG   209 SER A OG   1 
ATOM 3128 H H    . SER A 1 209 ? 53.244 -13.822 11.148 1.00 7.42  ? 209 SER A H    209 SER A H    1 
ATOM 3129 H HA   . SER A 1 209 ? 51.396 -15.739 10.015 1.00 7.42  ? 209 SER A HA   209 SER A HA   1 
ATOM 3130 H HB2  . SER A 1 209 ? 51.505 -17.059 11.958 1.00 7.42  ? 209 SER A HB2  209 SER A 1HB  1 
ATOM 3131 H HB3  . SER A 1 209 ? 53.128 -16.539 11.533 1.00 7.42  ? 209 SER A HB3  209 SER A 2HB  1 
ATOM 3132 H HG   . SER A 1 209 ? 51.463 -15.707 13.605 1.00 7.42  ? 209 SER A HG   209 SER A HG   1 
ATOM 3133 N N    . GLY A 1 210 ? 49.258 -14.414 11.591 1.00 7.12  ? 210 GLY A N    210 GLY A N    1 
ATOM 3134 C CA   . GLY A 1 210 ? 48.439 -13.360 12.278 1.00 7.12  ? 210 GLY A CA   210 GLY A CA   1 
ATOM 3135 C C    . GLY A 1 210 ? 47.650 -12.539 11.296 1.00 7.12  ? 210 GLY A C    210 GLY A C    1 
ATOM 3136 O O    . GLY A 1 210 ? 46.451 -12.050 11.747 1.00 7.12  ? 210 GLY A O    210 GLY A O    1 
ATOM 3137 H H    . GLY A 1 210 ? 48.926 -15.335 11.328 1.00 7.12  ? 210 GLY A H    210 GLY A H    1 
ATOM 3138 H HA2  . GLY A 1 210 ? 47.757 -13.832 12.986 1.00 7.12  ? 210 GLY A HA2  210 GLY A 1HA  1 
ATOM 3139 H HA3  . GLY A 1 210 ? 49.095 -12.706 12.852 1.00 7.12  ? 210 GLY A HA3  210 GLY A 2HA  1 
ATOM 3140 N N    . VAL A 1 211 ? 48.215 -12.615 9.889  1.00 6.50  ? 211 VAL A N    211 VAL A N    1 
ATOM 3141 C CA   . VAL A 1 211 ? 47.397 -11.841 8.872  1.00 6.50  ? 211 VAL A CA   211 VAL A CA   1 
ATOM 3142 C C    . VAL A 1 211 ? 46.371 -12.884 8.375  1.00 6.50  ? 211 VAL A C    211 VAL A C    1 
ATOM 3143 O O    . VAL A 1 211 ? 46.875 -14.029 7.799  1.00 6.50  ? 211 VAL A O    211 VAL A O    1 
ATOM 3144 C CB   . VAL A 1 211 ? 48.244 -11.305 7.703  1.00 6.50  ? 211 VAL A CB   211 VAL A CB   1 
ATOM 3145 C CG1  . VAL A 1 211 ? 47.356 -10.638 6.664  1.00 6.50  ? 211 VAL A CG1  211 VAL A CG1  1 
ATOM 3146 C CG2  . VAL A 1 211 ? 49.289 -10.331 8.225  1.00 6.50  ? 211 VAL A CG2  211 VAL A CG2  1 
ATOM 3147 H H    . VAL A 1 211 ? 49.129 -12.860 9.601  1.00 6.50  ? 211 VAL A H    211 VAL A H    1 
ATOM 3148 H HA   . VAL A 1 211 ? 46.947 -10.982 9.372  1.00 6.50  ? 211 VAL A HA   211 VAL A HA   1 
ATOM 3149 H HB   . VAL A 1 211 ? 48.740 -12.143 7.212  1.00 6.50  ? 211 VAL A HB   211 VAL A HB   1 
ATOM 3150 H HG11 . VAL A 1 211 ? 47.971 -10.266 5.844  1.00 6.50  ? 211 VAL A HG11 211 VAL A 1HG1 1 
ATOM 3151 H HG12 . VAL A 1 211 ? 46.640 -11.363 6.278  1.00 6.50  ? 211 VAL A HG12 211 VAL A 2HG1 1 
ATOM 3152 H HG13 . VAL A 1 211 ? 46.821 -9.807  7.122  1.00 6.50  ? 211 VAL A HG13 211 VAL A 3HG1 1 
ATOM 3153 H HG21 . VAL A 1 211 ? 49.885 -9.957  7.393  1.00 6.50  ? 211 VAL A HG21 211 VAL A 1HG2 1 
ATOM 3154 H HG22 . VAL A 1 211 ? 48.793 -9.497  8.721  1.00 6.50  ? 211 VAL A HG22 211 VAL A 2HG2 1 
ATOM 3155 H HG23 . VAL A 1 211 ? 49.939 -10.841 8.936  1.00 6.50  ? 211 VAL A HG23 211 VAL A 3HG2 1 
ATOM 3156 N N    . PRO A 1 212 ? 44.973 -12.297 8.442  1.00 6.40  ? 212 PRO A N    212 PRO A N    1 
ATOM 3157 C CA   . PRO A 1 212 ? 43.793 -13.014 8.033  1.00 6.40  ? 212 PRO A CA   212 PRO A CA   1 
ATOM 3158 C C    . PRO A 1 212 ? 43.996 -13.301 6.670  1.00 6.40  ? 212 PRO A C    212 PRO A C    1 
ATOM 3159 O O    . PRO A 1 212 ? 44.502 -12.229 6.102  1.00 6.40  ? 212 PRO A O    212 PRO A O    1 
ATOM 3160 C CB   . PRO A 1 212 ? 42.623 -12.049 8.244  1.00 6.40  ? 212 PRO A CB   212 PRO A CB   1 
ATOM 3161 C CG   . PRO A 1 212 ? 43.066 -11.177 9.369  1.00 6.40  ? 212 PRO A CG   212 PRO A CG   1 
ATOM 3162 C CD   . PRO A 1 212 ? 44.548 -11.020 9.160  1.00 6.40  ? 212 PRO A CD   212 PRO A CD   1 
ATOM 3163 H HA   . PRO A 1 212 ? 43.666 -13.897 8.676  1.00 6.40  ? 212 PRO A HA   212 PRO A HA   1 
ATOM 3164 H HB2  . PRO A 1 212 ? 42.428 -11.485 7.319  1.00 6.40  ? 212 PRO A HB2  212 PRO A 1HB  1 
ATOM 3165 H HB3  . PRO A 1 212 ? 41.707 -12.612 8.475  1.00 6.40  ? 212 PRO A HB3  212 PRO A 2HB  1 
ATOM 3166 H HG2  . PRO A 1 212 ? 42.530 -10.217 9.340  1.00 6.40  ? 212 PRO A HG2  212 PRO A 1HG  1 
ATOM 3167 H HG3  . PRO A 1 212 ? 42.822 -11.648 10.333 1.00 6.40  ? 212 PRO A HG3  212 PRO A 2HG  1 
ATOM 3168 H HD2  . PRO A 1 212 ? 44.739 -10.141 8.527  1.00 6.40  ? 212 PRO A HD2  212 PRO A 1HD  1 
ATOM 3169 H HD3  . PRO A 1 212 ? 45.047 -10.913 10.134 1.00 6.40  ? 212 PRO A HD3  212 PRO A 2HD  1 
ATOM 3170 N N    . ASP A 1 213 ? 43.485 -14.691 6.247  1.00 6.59  ? 213 ASP A N    213 ASP A N    1 
ATOM 3171 C CA   . ASP A 1 213 ? 43.596 -15.148 4.806  1.00 6.59  ? 213 ASP A CA   213 ASP A CA   1 
ATOM 3172 C C    . ASP A 1 213 ? 42.761 -14.226 3.927  1.00 6.59  ? 213 ASP A C    213 ASP A C    1 
ATOM 3173 O O    . ASP A 1 213 ? 43.163 -14.408 2.692  1.00 6.59  ? 213 ASP A O    213 ASP A O    1 
ATOM 3174 C CB   . ASP A 1 213 ? 43.120 -16.592 4.625  1.00 6.59  ? 213 ASP A CB   213 ASP A CB   1 
ATOM 3175 C CG   . ASP A 1 213 ? 44.087 -17.612 5.211  1.00 6.59  ? 213 ASP A CG   213 ASP A CG   1 
ATOM 3176 O OD1  . ASP A 1 213 ? 45.195 -17.242 5.520  1.00 6.59  ? 213 ASP A OD1  213 ASP A OD1  1 
ATOM 3177 O OD2  . ASP A 1 213 ? 43.709 -18.751 5.343  1.00 6.59  ? 213 ASP A OD2  213 ASP A OD2  1 
ATOM 3178 H H    . ASP A 1 213 ? 43.119 -15.311 6.971  1.00 6.59  ? 213 ASP A H    213 ASP A H    1 
ATOM 3179 H HA   . ASP A 1 213 ? 44.644 -15.100 4.508  1.00 6.59  ? 213 ASP A HA   213 ASP A HA   1 
ATOM 3180 H HB2  . ASP A 1 213 ? 42.149 -16.717 5.103  1.00 6.59  ? 213 ASP A HB2  213 ASP A 1HB  1 
ATOM 3181 H HB3  . ASP A 1 213 ? 42.992 -16.802 3.563  1.00 6.59  ? 213 ASP A HB3  213 ASP A 2HB  1 
ATOM 3182 N N    . ARG A 1 214 ? 41.715 -13.205 4.497  1.00 5.93  ? 214 ARG A N    214 ARG A N    1 
ATOM 3183 C CA   . ARG A 1 214 ? 41.060 -12.596 3.385  1.00 5.93  ? 214 ARG A CA   214 ARG A CA   1 
ATOM 3184 C C    . ARG A 1 214 ? 41.980 -11.460 2.842  1.00 5.93  ? 214 ARG A C    214 ARG A C    1 
ATOM 3185 O O    . ARG A 1 214 ? 41.663 -11.041 1.612  1.00 5.93  ? 214 ARG A O    214 ARG A O    1 
ATOM 3186 C CB   . ARG A 1 214 ? 39.702 -12.048 3.799  1.00 5.93  ? 214 ARG A CB   214 ARG A CB   1 
ATOM 3187 C CG   . ARG A 1 214 ? 38.695 -13.099 4.238  1.00 5.93  ? 214 ARG A CG   214 ARG A CG   1 
ATOM 3188 C CD   . ARG A 1 214 ? 37.300 -12.599 4.135  1.00 5.93  ? 214 ARG A CD   214 ARG A CD   1 
ATOM 3189 N NE   . ARG A 1 214 ? 37.091 -11.404 4.937  1.00 5.93  ? 214 ARG A NE   214 ARG A NE   1 
ATOM 3190 C CZ   . ARG A 1 214 ? 36.851 -11.405 6.263  1.00 5.93  ? 214 ARG A CZ   214 ARG A CZ   1 
ATOM 3191 N NH1  . ARG A 1 214 ? 36.793 -12.543 6.920  1.00 5.93  ? 214 ARG A NH1  214 ARG A NH1  1 
ATOM 3192 N NH2  . ARG A 1 214 ? 36.675 -10.263 6.904  1.00 5.93  ? 214 ARG A NH2  214 ARG A NH2  1 
ATOM 3193 H H    . ARG A 1 214 ? 41.480 -13.010 5.465  1.00 5.93  ? 214 ARG A H    214 ARG A H    1 
ATOM 3194 H HA   . ARG A 1 214 ? 40.909 -13.353 2.615  1.00 5.93  ? 214 ARG A HA   214 ARG A HA   1 
ATOM 3195 H HB2  . ARG A 1 214 ? 39.829 -11.348 4.624  1.00 5.93  ? 214 ARG A HB2  214 ARG A 1HB  1 
ATOM 3196 H HB3  . ARG A 1 214 ? 39.263 -11.497 2.967  1.00 5.93  ? 214 ARG A HB3  214 ARG A 2HB  1 
ATOM 3197 H HG2  . ARG A 1 214 ? 38.790 -13.981 3.605  1.00 5.93  ? 214 ARG A HG2  214 ARG A 1HG  1 
ATOM 3198 H HG3  . ARG A 1 214 ? 38.885 -13.374 5.276  1.00 5.93  ? 214 ARG A HG3  214 ARG A 2HG  1 
ATOM 3199 H HD2  . ARG A 1 214 ? 37.076 -12.356 3.097  1.00 5.93  ? 214 ARG A HD2  214 ARG A 1HD  1 
ATOM 3200 H HD3  . ARG A 1 214 ? 36.612 -13.368 4.484  1.00 5.93  ? 214 ARG A HD3  214 ARG A 2HD  1 
ATOM 3201 H HE   . ARG A 1 214 ? 37.129 -10.510 4.467  1.00 5.93  ? 214 ARG A HE   214 ARG A HE   1 
ATOM 3202 H HH11 . ARG A 1 214 ? 36.928 -13.416 6.430  1.00 5.93  ? 214 ARG A HH11 214 ARG A 1HH1 1 
ATOM 3203 H HH12 . ARG A 1 214 ? 36.613 -12.543 7.913  1.00 5.93  ? 214 ARG A HH12 214 ARG A 2HH1 1 
ATOM 3204 H HH21 . ARG A 1 214 ? 36.720 -9.388  6.399  1.00 5.93  ? 214 ARG A HH21 214 ARG A 1HH2 1 
ATOM 3205 H HH22 . ARG A 1 214 ? 36.495 -10.263 7.896  1.00 5.93  ? 214 ARG A HH22 214 ARG A 2HH2 1 
ATOM 3206 N N    . PHE A 1 215 ? 43.286 -11.114 3.635  1.00 5.77  ? 215 PHE A N    215 PHE A N    1 
ATOM 3207 C CA   . PHE A 1 215 ? 43.899 -9.974  3.259  1.00 5.77  ? 215 PHE A CA   215 PHE A CA   1 
ATOM 3208 C C    . PHE A 1 215 ? 45.293 -10.274 2.803  1.00 5.77  ? 215 PHE A C    215 PHE A C    1 
ATOM 3209 O O    . PHE A 1 215 ? 45.954 -11.036 3.643  1.00 5.77  ? 215 PHE A O    215 PHE A O    1 
ATOM 3210 C CB   . PHE A 1 215 ? 43.898 -8.984  4.426  1.00 5.77  ? 215 PHE A CB   215 PHE A CB   1 
ATOM 3211 C CG   . PHE A 1 215 ? 42.552 -8.812  5.072  1.00 5.77  ? 215 PHE A CG   215 PHE A CG   1 
ATOM 3212 C CD1  . PHE A 1 215 ? 42.409 -8.916  6.447  1.00 5.77  ? 215 PHE A CD1  215 PHE A CD1  1 
ATOM 3213 C CD2  . PHE A 1 215 ? 41.428 -8.545  4.306  1.00 5.77  ? 215 PHE A CD2  215 PHE A CD2  1 
ATOM 3214 C CE1  . PHE A 1 215 ? 41.171 -8.758  7.043  1.00 5.77  ? 215 PHE A CE1  215 PHE A CE1  1 
ATOM 3215 C CE2  . PHE A 1 215 ? 40.190 -8.384  4.898  1.00 5.77  ? 215 PHE A CE2  215 PHE A CE2  1 
ATOM 3216 C CZ   . PHE A 1 215 ? 40.062 -8.492  6.268  1.00 5.77  ? 215 PHE A CZ   215 PHE A CZ   1 
ATOM 3217 H H    . PHE A 1 215 ? 43.724 -11.630 4.266  1.00 5.77  ? 215 PHE A H    215 PHE A H    1 
ATOM 3218 H HA   . PHE A 1 215 ? 43.347 -9.542  2.424  1.00 5.77  ? 215 PHE A HA   215 PHE A HA   1 
ATOM 3219 H HB2  . PHE A 1 215 ? 44.600 -9.319  5.188  1.00 5.77  ? 215 PHE A HB2  215 PHE A 1HB  1 
ATOM 3220 H HB3  . PHE A 1 215 ? 44.235 -8.009  4.076  1.00 5.77  ? 215 PHE A HB3  215 PHE A 2HB  1 
ATOM 3221 H HD1  . PHE A 1 215 ? 43.286 -9.126  7.060  1.00 5.77  ? 215 PHE A HD1  215 PHE A HD1  1 
ATOM 3222 H HD2  . PHE A 1 215 ? 41.529 -8.460  3.223  1.00 5.77  ? 215 PHE A HD2  215 PHE A HD2  1 
ATOM 3223 H HE1  . PHE A 1 215 ? 41.073 -8.843  8.125  1.00 5.77  ? 215 PHE A HE1  215 PHE A HE1  1 
ATOM 3224 H HE2  . PHE A 1 215 ? 39.314 -8.174  4.284  1.00 5.77  ? 215 PHE A HE2  215 PHE A HE2  1 
ATOM 3225 H HZ   . PHE A 1 215 ? 39.087 -8.367  6.736  1.00 5.77  ? 215 PHE A HZ   215 PHE A HZ   1 
ATOM 3226 N N    . SER A 1 216 ? 45.668 -9.661  1.480  1.00 5.74  ? 216 SER A N    216 SER A N    1 
ATOM 3227 C CA   . SER A 1 216 ? 47.015 -9.857  0.966  1.00 5.74  ? 216 SER A CA   216 SER A CA   1 
ATOM 3228 C C    . SER A 1 216 ? 47.654 -8.561  0.429  1.00 5.74  ? 216 SER A C    216 SER A C    1 
ATOM 3229 O O    . SER A 1 216 ? 47.071 -8.031  -0.611 1.00 5.74  ? 216 SER A O    216 SER A O    1 
ATOM 3230 C CB   . SER A 1 216 ? 46.985 -10.903 -0.131 1.00 5.74  ? 216 SER A CB   216 SER A CB   1 
ATOM 3231 O OG   . SER A 1 216 ? 48.253 -11.064 -0.707 1.00 5.74  ? 216 SER A OG   216 SER A OG   1 
ATOM 3232 H H    . SER A 1 216 ? 45.007 -9.076  1.088  1.00 5.74  ? 216 SER A H    216 SER A H    1 
ATOM 3233 H HA   . SER A 1 216 ? 47.649 -10.210 1.781  1.00 5.74  ? 216 SER A HA   216 SER A HA   1 
ATOM 3234 H HB2  . SER A 1 216 ? 46.647 -11.854 0.281  1.00 5.74  ? 216 SER A HB2  216 SER A 1HB  1 
ATOM 3235 H HB3  . SER A 1 216 ? 46.270 -10.607 -0.897 1.00 5.74  ? 216 SER A HB3  216 SER A 2HB  1 
ATOM 3236 H HG   . SER A 1 216 ? 48.828 -10.438 -0.260 1.00 5.74  ? 216 SER A HG   216 SER A HG   1 
ATOM 3237 N N    . GLY A 1 217 ? 48.861 -8.024  1.169  1.00 5.56  ? 217 GLY A N    217 GLY A N    1 
ATOM 3238 C CA   . GLY A 1 217 ? 49.481 -6.889  0.635  1.00 5.56  ? 217 GLY A CA   217 GLY A CA   1 
ATOM 3239 C C    . GLY A 1 217 ? 50.649 -7.189  -0.237 1.00 5.56  ? 217 GLY A C    217 GLY A C    1 
ATOM 3240 O O    . GLY A 1 217 ? 51.343 -8.142  0.162  1.00 5.56  ? 217 GLY A O    217 GLY A O    1 
ATOM 3241 H H    . GLY A 1 217 ? 49.240 -8.493  1.997  1.00 5.56  ? 217 GLY A H    217 GLY A H    1 
ATOM 3242 H HA2  . GLY A 1 217 ? 48.758 -6.320  0.051  1.00 5.56  ? 217 GLY A HA2  217 GLY A 1HA  1 
ATOM 3243 H HA3  . GLY A 1 217 ? 49.818 -6.244  1.445  1.00 5.56  ? 217 GLY A HA3  217 GLY A 2HA  1 
ATOM 3244 N N    . SER A 1 218 ? 50.896 -6.299  -1.325 1.00 5.52  ? 218 SER A N    218 SER A N    1 
ATOM 3245 C CA   . SER A 1 218 ? 52.027 -6.377  -2.242 1.00 5.52  ? 218 SER A CA   218 SER A CA   1 
ATOM 3246 C C    . SER A 1 218 ? 52.638 -5.006  -2.349 1.00 5.52  ? 218 SER A C    218 SER A C    1 
ATOM 3247 O O    . SER A 1 218 ? 51.810 -4.068  -2.805 1.00 5.52  ? 218 SER A O    218 SER A O    1 
ATOM 3248 C CB   . SER A 1 218 ? 51.592 -6.868  -3.609 1.00 5.52  ? 218 SER A CB   218 SER A CB   1 
ATOM 3249 O OG   . SER A 1 218 ? 52.667 -6.869  -4.508 1.00 5.52  ? 218 SER A OG   218 SER A OG   1 
ATOM 3250 H H    . SER A 1 218 ? 50.267 -5.651  -1.487 1.00 5.52  ? 218 SER A H    218 SER A H    1 
ATOM 3251 H HA   . SER A 1 218 ? 52.752 -7.085  -1.839 1.00 5.52  ? 218 SER A HA   218 SER A HA   1 
ATOM 3252 H HB2  . SER A 1 218 ? 51.186 -7.876  -3.521 1.00 5.52  ? 218 SER A HB2  218 SER A 1HB  1 
ATOM 3253 H HB3  . SER A 1 218 ? 50.797 -6.228  -3.990 1.00 5.52  ? 218 SER A HB3  218 SER A 2HB  1 
ATOM 3254 H HG   . SER A 1 218 ? 53.417 -6.515  -4.024 1.00 5.52  ? 218 SER A HG   218 SER A HG   1 
ATOM 3255 N N    . GLY A 1 219 ? 54.041 -4.836  -1.721 1.00 5.24  ? 219 GLY A N    219 GLY A N    1 
ATOM 3256 C CA   . GLY A 1 219 ? 54.594 -3.512  -1.847 1.00 5.24  ? 219 GLY A CA   219 GLY A CA   1 
ATOM 3257 C C    . GLY A 1 219 ? 55.495 -3.544  -2.990 1.00 5.24  ? 219 GLY A C    219 GLY A C    1 
ATOM 3258 O O    . GLY A 1 219 ? 56.157 -4.636  -2.994 1.00 5.24  ? 219 GLY A O    219 GLY A O    1 
ATOM 3259 H H    . GLY A 1 219 ? 54.578 -5.621  -1.339 1.00 5.24  ? 219 GLY A H    219 GLY A H    1 
ATOM 3260 H HA2  . GLY A 1 219 ? 53.787 -2.792  -1.982 1.00 5.24  ? 219 GLY A HA2  219 GLY A 1HA  1 
ATOM 3261 H HA3  . GLY A 1 219 ? 55.112 -3.245  -0.926 1.00 5.24  ? 219 GLY A HA3  219 GLY A 2HA  1 
ATOM 3262 N N    . SER A 1 220 ? 55.620 -2.331  -3.803 1.00 5.85  ? 220 SER A N    220 SER A N    1 
ATOM 3263 C CA   . SER A 1 220 ? 56.604 -2.175  -4.878 1.00 5.85  ? 220 SER A CA   220 SER A CA   1 
ATOM 3264 C C    . SER A 1 220 ? 57.092 -0.803  -4.601 1.00 5.85  ? 220 SER A C    220 SER A C    1 
ATOM 3265 O O    . SER A 1 220 ? 56.302 0.110   -5.127 1.00 5.85  ? 220 SER A O    220 SER A O    1 
ATOM 3266 C CB   . SER A 1 220 ? 56.008 -2.293  -6.267 1.00 5.85  ? 220 SER A CB   220 SER A CB   1 
ATOM 3267 O OG   . SER A 1 220 ? 56.994 -2.138  -7.251 1.00 5.85  ? 220 SER A OG   220 SER A OG   1 
ATOM 3268 H H    . SER A 1 220 ? 55.068 -1.567  -3.644 1.00 5.85  ? 220 SER A H    220 SER A H    1 
ATOM 3269 H HA   . SER A 1 220 ? 57.351 -2.963  -4.781 1.00 5.85  ? 220 SER A HA   220 SER A HA   1 
ATOM 3270 H HB2  . SER A 1 220 ? 55.531 -3.267  -6.377 1.00 5.85  ? 220 SER A HB2  220 SER A 1HB  1 
ATOM 3271 H HB3  . SER A 1 220 ? 55.238 -1.535  -6.399 1.00 5.85  ? 220 SER A HB3  220 SER A 2HB  1 
ATOM 3272 H HG   . SER A 1 220 ? 57.832 -2.314  -6.816 1.00 5.85  ? 220 SER A HG   220 SER A HG   1 
ATOM 3273 N N    . GLY A 1 221 ? 58.412 -0.676  -3.746 1.00 5.09  ? 221 GLY A N    221 GLY A N    1 
ATOM 3274 C CA   . GLY A 1 221 ? 58.835 0.700   -3.588 1.00 5.09  ? 221 GLY A CA   221 GLY A CA   1 
ATOM 3275 C C    . GLY A 1 221 ? 57.831 1.770   -2.934 1.00 5.09  ? 221 GLY A C    221 GLY A C    1 
ATOM 3276 O O    . GLY A 1 221 ? 57.879 1.835   -1.614 1.00 5.09  ? 221 GLY A O    221 GLY A O    1 
ATOM 3277 H H    . GLY A 1 221 ? 58.898 -1.461  -3.345 1.00 5.09  ? 221 GLY A H    221 GLY A H    1 
ATOM 3278 H HA2  . GLY A 1 221 ? 59.732 0.737   -2.971 1.00 5.09  ? 221 GLY A HA2  221 GLY A 1HA  1 
ATOM 3279 H HA3  . GLY A 1 221 ? 59.097 1.114   -4.561 1.00 5.09  ? 221 GLY A HA3  221 GLY A 2HA  1 
ATOM 3280 N N    . THR A 1 222 ? 57.113 2.695   -3.966 1.00 4.70  ? 222 THR A N    222 THR A N    1 
ATOM 3281 C CA   . THR A 1 222 ? 56.340 3.644   -3.250 1.00 4.70  ? 222 THR A CA   222 THR A CA   1 
ATOM 3282 C C    . THR A 1 222 ? 54.840 3.255   -3.263 1.00 4.70  ? 222 THR A C    222 THR A C    1 
ATOM 3283 O O    . THR A 1 222 ? 54.137 3.583   -2.143 1.00 4.70  ? 222 THR A O    222 THR A O    1 
ATOM 3284 C CB   . THR A 1 222 ? 56.545 5.051   -3.843 1.00 4.70  ? 222 THR A CB   222 THR A CB   1 
ATOM 3285 O OG1  . THR A 1 222 ? 56.150 5.053   -5.221 1.00 4.70  ? 222 THR A OG1  222 THR A OG1  1 
ATOM 3286 C CG2  . THR A 1 222 ? 58.003 5.467   -3.737 1.00 4.70  ? 222 THR A CG2  222 THR A CG2  1 
ATOM 3287 H H    . THR A 1 222 ? 56.811 1.855   -4.559 1.00 4.70  ? 222 THR A H    222 THR A H    1 
ATOM 3288 H HA   . THR A 1 222 ? 56.672 3.649   -2.212 1.00 4.70  ? 222 THR A HA   222 THR A HA   1 
ATOM 3289 H HB   . THR A 1 222 ? 55.927 5.767   -3.301 1.00 4.70  ? 222 THR A HB   222 THR A HB   1 
ATOM 3290 H HG1  . THR A 1 222 ? 55.342 4.544   -5.323 1.00 4.70  ? 222 THR A HG1  222 THR A HG1  1 
ATOM 3291 H HG21 . THR A 1 222 ? 58.129 6.464   -4.160 1.00 4.70  ? 222 THR A HG21 222 THR A 1HG2 1 
ATOM 3292 H HG22 . THR A 1 222 ? 58.303 5.477   -2.689 1.00 4.70  ? 222 THR A HG22 222 THR A 2HG2 1 
ATOM 3293 H HG23 . THR A 1 222 ? 58.625 4.760   -4.285 1.00 4.70  ? 222 THR A HG23 222 THR A 3HG2 1 
ATOM 3294 N N    . ASP A 1 223 ? 54.427 2.203   -4.354 1.00 4.95  ? 223 ASP A N    223 ASP A N    1 
ATOM 3295 C CA   . ASP A 1 223 ? 53.064 1.879   -4.375 1.00 4.95  ? 223 ASP A CA   223 ASP A CA   1 
ATOM 3296 C C    . ASP A 1 223 ? 52.812 0.530   -3.718 1.00 4.95  ? 223 ASP A C    223 ASP A C    1 
ATOM 3297 O O    . ASP A 1 223 ? 53.695 -0.307  -4.224 1.00 4.95  ? 223 ASP A O    223 ASP A O    1 
ATOM 3298 C CB   . ASP A 1 223 ? 52.556 1.879   -5.819 1.00 4.95  ? 223 ASP A CB   223 ASP A CB   1 
ATOM 3299 C CG   . ASP A 1 223 ? 52.698 3.235   -6.497 1.00 4.95  ? 223 ASP A CG   223 ASP A CG   1 
ATOM 3300 O OD1  . ASP A 1 223 ? 53.003 4.187   -5.819 1.00 4.95  ? 223 ASP A OD1  223 ASP A OD1  1 
ATOM 3301 O OD2  . ASP A 1 223 ? 52.500 3.305   -7.686 1.00 4.95  ? 223 ASP A OD2  223 ASP A OD2  1 
ATOM 3302 H H    . ASP A 1 223 ? 55.069 1.763   -4.925 1.00 4.95  ? 223 ASP A H    223 ASP A H    1 
ATOM 3303 H HA   . ASP A 1 223 ? 52.521 2.634   -3.806 1.00 4.95  ? 223 ASP A HA   223 ASP A HA   1 
ATOM 3304 H HB2  . ASP A 1 223 ? 53.108 1.139   -6.399 1.00 4.95  ? 223 ASP A HB2  223 ASP A 1HB  1 
ATOM 3305 H HB3  . ASP A 1 223 ? 51.505 1.589   -5.834 1.00 4.95  ? 223 ASP A HB3  223 ASP A 2HB  1 
ATOM 3306 N N    . PHE A 1 224 ? 51.690 0.439   -2.727 1.00 5.07  ? 224 PHE A N    224 PHE A N    1 
ATOM 3307 C CA   . PHE A 1 224 ? 51.330 -0.662  -2.017 1.00 5.07  ? 224 PHE A CA   224 PHE A CA   1 
ATOM 3308 C C    . PHE A 1 224 ? 49.885 -1.018  -2.373 1.00 5.07  ? 224 PHE A C    224 PHE A C    1 
ATOM 3309 O O    . PHE A 1 224 ? 48.995 -0.062  -2.461 1.00 5.07  ? 224 PHE A O    224 PHE A O    1 
ATOM 3310 C CB   . PHE A 1 224 ? 51.499 -0.386  -0.522 1.00 5.07  ? 224 PHE A CB   224 PHE A CB   1 
ATOM 3311 C CG   . PHE A 1 224 ? 52.036 -1.556  0.253  1.00 5.07  ? 224 PHE A CG   224 PHE A CG   1 
ATOM 3312 C CD1  . PHE A 1 224 ? 53.178 -1.426  1.030  1.00 5.07  ? 224 PHE A CD1  224 PHE A CD1  1 
ATOM 3313 C CD2  . PHE A 1 224 ? 51.401 -2.788  0.208  1.00 5.07  ? 224 PHE A CD2  224 PHE A CD2  1 
ATOM 3314 C CE1  . PHE A 1 224 ? 53.673 -2.502  1.743  1.00 5.07  ? 224 PHE A CE1  224 PHE A CE1  1 
ATOM 3315 C CE2  . PHE A 1 224 ? 51.892 -3.864  0.920  1.00 5.07  ? 224 PHE A CE2  224 PHE A CE2  1 
ATOM 3316 C CZ   . PHE A 1 224 ? 53.030 -3.720  1.689  1.00 5.07  ? 224 PHE A CZ   224 PHE A CZ   1 
ATOM 3317 H H    . PHE A 1 224 ? 51.133 1.145   -2.628 1.00 5.07  ? 224 PHE A H    224 PHE A H    1 
ATOM 3318 H HA   . PHE A 1 224 ? 51.984 -1.487  -2.303 1.00 5.07  ? 224 PHE A HA   224 PHE A HA   1 
ATOM 3319 H HB2  . PHE A 1 224 ? 52.176 0.455   -0.381 1.00 5.07  ? 224 PHE A HB2  224 PHE A 1HB  1 
ATOM 3320 H HB3  . PHE A 1 224 ? 50.537 -0.107  -0.093 1.00 5.07  ? 224 PHE A HB3  224 PHE A 2HB  1 
ATOM 3321 H HD1  . PHE A 1 224 ? 53.685 -0.462  1.073  1.00 5.07  ? 224 PHE A HD1  224 PHE A HD1  1 
ATOM 3322 H HD2  . PHE A 1 224 ? 50.502 -2.901  -0.400 1.00 5.07  ? 224 PHE A HD2  224 PHE A HD2  1 
ATOM 3323 H HE1  . PHE A 1 224 ? 54.571 -2.386  2.349  1.00 5.07  ? 224 PHE A HE1  224 PHE A HE1  1 
ATOM 3324 H HE2  . PHE A 1 224 ? 51.383 -4.826  0.876  1.00 5.07  ? 224 PHE A HE2  224 PHE A HE2  1 
ATOM 3325 H HZ   . PHE A 1 224 ? 53.420 -4.568  2.250  1.00 5.07  ? 224 PHE A HZ   224 PHE A HZ   1 
ATOM 3326 N N    . THR A 1 225 ? 49.617 -2.464  -2.768 1.00 5.35  ? 225 THR A N    225 THR A N    1 
ATOM 3327 C CA   . THR A 1 225 ? 48.275 -2.791  -3.091 1.00 5.35  ? 225 THR A CA   225 THR A CA   1 
ATOM 3328 C C    . THR A 1 225 ? 47.812 -3.781  -2.112 1.00 5.35  ? 225 THR A C    225 THR A C    1 
ATOM 3329 O O    . THR A 1 225 ? 48.646 -4.769  -1.980 1.00 5.35  ? 225 THR A O    225 THR A O    1 
ATOM 3330 C CB   . THR A 1 225 ? 48.136 -3.347  -4.520 1.00 5.35  ? 225 THR A CB   225 THR A CB   1 
ATOM 3331 O OG1  . THR A 1 225 ? 48.573 -2.360  -5.464 1.00 5.35  ? 225 THR A OG1  225 THR A OG1  1 
ATOM 3332 C CG2  . THR A 1 225 ? 46.690 -3.717  -4.810 1.00 5.35  ? 225 THR A CG2  225 THR A CG2  1 
ATOM 3333 H H    . THR A 1 225 ? 50.288 -3.099  -2.814 1.00 5.35  ? 225 THR A H    225 THR A H    1 
ATOM 3334 H HA   . THR A 1 225 ? 47.673 -1.885  -3.027 1.00 5.35  ? 225 THR A HA   225 THR A HA   1 
ATOM 3335 H HB   . THR A 1 225 ? 48.761 -4.234  -4.628 1.00 5.35  ? 225 THR A HB   225 THR A HB   1 
ATOM 3336 H HG1  . THR A 1 225 ? 47.863 -1.733  -5.621 1.00 5.35  ? 225 THR A HG1  225 THR A HG1  1 
ATOM 3337 H HG21 . THR A 1 225 ? 46.611 -4.108  -5.825 1.00 5.35  ? 225 THR A HG21 225 THR A 1HG2 1 
ATOM 3338 H HG22 . THR A 1 225 ? 46.359 -4.476  -4.102 1.00 5.35  ? 225 THR A HG22 225 THR A 2HG2 1 
ATOM 3339 H HG23 . THR A 1 225 ? 46.062 -2.832  -4.714 1.00 5.35  ? 225 THR A HG23 225 THR A 3HG2 1 
ATOM 3340 N N    . LEU A 1 226 ? 46.509 -3.423  -1.338 1.00 5.47  ? 226 LEU A N    226 LEU A N    1 
ATOM 3341 C CA   . LEU A 1 226 ? 45.846 -4.310  -0.480 1.00 5.47  ? 226 LEU A CA   226 LEU A CA   1 
ATOM 3342 C C    . LEU A 1 226 ? 44.751 -5.041  -1.258 1.00 5.47  ? 226 LEU A C    226 LEU A C    1 
ATOM 3343 O O    . LEU A 1 226 ? 43.947 -4.231  -1.915 1.00 5.47  ? 226 LEU A O    226 LEU A O    1 
ATOM 3344 C CB   . LEU A 1 226 ? 45.258 -3.542  0.711  1.00 5.47  ? 226 LEU A CB   226 LEU A CB   1 
ATOM 3345 C CG   . LEU A 1 226 ? 44.014 -4.166  1.356  1.00 5.47  ? 226 LEU A CG   226 LEU A CG   1 
ATOM 3346 C CD1  . LEU A 1 226 ? 44.405 -5.447  2.080  1.00 5.47  ? 226 LEU A CD1  226 LEU A CD1  1 
ATOM 3347 C CD2  . LEU A 1 226 ? 43.385 -3.166  2.316  1.00 5.47  ? 226 LEU A CD2  226 LEU A CD2  1 
ATOM 3348 H H    . LEU A 1 226 ? 46.073 -2.668  -1.537 1.00 5.47  ? 226 LEU A H    226 LEU A H    1 
ATOM 3349 H HA   . LEU A 1 226 ? 46.567 -5.038  -0.111 1.00 5.47  ? 226 LEU A HA   226 LEU A HA   1 
ATOM 3350 H HB2  . LEU A 1 226 ? 46.024 -3.457  1.481  1.00 5.47  ? 226 LEU A HB2  226 LEU A 1HB  1 
ATOM 3351 H HB3  . LEU A 1 226 ? 44.992 -2.539  0.380  1.00 5.47  ? 226 LEU A HB3  226 LEU A 2HB  1 
ATOM 3352 H HG   . LEU A 1 226 ? 43.294 -4.427  0.581  1.00 5.47  ? 226 LEU A HG   226 LEU A HG   1 
ATOM 3353 H HD11 . LEU A 1 226 ? 43.521 -5.890  2.539  1.00 5.47  ? 226 LEU A HD11 226 LEU A 1HD1 1 
ATOM 3354 H HD12 . LEU A 1 226 ? 44.835 -6.151  1.367  1.00 5.47  ? 226 LEU A HD12 226 LEU A 2HD1 1 
ATOM 3355 H HD13 . LEU A 1 226 ? 45.139 -5.220  2.852  1.00 5.47  ? 226 LEU A HD13 226 LEU A 3HD1 1 
ATOM 3356 H HD21 . LEU A 1 226 ? 42.501 -3.609  2.774  1.00 5.47  ? 226 LEU A HD21 226 LEU A 1HD2 1 
ATOM 3357 H HD22 . LEU A 1 226 ? 44.104 -2.905  3.093  1.00 5.47  ? 226 LEU A HD22 226 LEU A 2HD2 1 
ATOM 3358 H HD23 . LEU A 1 226 ? 43.099 -2.268  1.769  1.00 5.47  ? 226 LEU A HD23 226 LEU A 3HD2 1 
ATOM 3359 N N    . THR A 1 227 ? 44.825 -6.623  -1.233 1.00 5.61  ? 227 THR A N    227 THR A N    1 
ATOM 3360 C CA   . THR A 1 227 ? 43.852 -7.356  -1.830 1.00 5.61  ? 227 THR A CA   227 THR A CA   1 
ATOM 3361 C C    . THR A 1 227 ? 42.949 -7.850  -0.697 1.00 5.61  ? 227 THR A C    227 THR A C    1 
ATOM 3362 O O    . THR A 1 227 ? 43.270 -8.367  0.311  1.00 5.61  ? 227 THR A O    227 THR A O    1 
ATOM 3363 C CB   . THR A 1 227 ? 44.454 -8.512  -2.651 1.00 5.61  ? 227 THR A CB   227 THR A CB   1 
ATOM 3364 O OG1  . THR A 1 227 ? 45.303 -7.981  -3.677 1.00 5.61  ? 227 THR A OG1  227 THR A OG1  1 
ATOM 3365 C CG2  . THR A 1 227 ? 43.352 -9.343  -3.290 1.00 5.61  ? 227 THR A CG2  227 THR A CG2  1 
ATOM 3366 H H    . THR A 1 227 ? 45.498 -7.114  -0.851 1.00 5.61  ? 227 THR A H    227 THR A H    1 
ATOM 3367 H HA   . THR A 1 227 ? 43.296 -6.707  -2.507 1.00 5.61  ? 227 THR A HA   227 THR A HA   1 
ATOM 3368 H HB   . THR A 1 227 ? 45.051 -9.149  -1.999 1.00 5.61  ? 227 THR A HB   227 THR A HB   1 
ATOM 3369 H HG1  . THR A 1 227 ? 46.165 -7.777  -3.305 1.00 5.61  ? 227 THR A HG1  227 THR A HG1  1 
ATOM 3370 H HG21 . THR A 1 227 ? 43.796 -10.155 -3.865 1.00 5.61  ? 227 THR A HG21 227 THR A 1HG2 1 
ATOM 3371 H HG22 . THR A 1 227 ? 42.712 -9.758  -2.511 1.00 5.61  ? 227 THR A HG22 227 THR A 2HG2 1 
ATOM 3372 H HG23 . THR A 1 227 ? 42.758 -8.713  -3.950 1.00 5.61  ? 227 THR A HG23 227 THR A 3HG2 1 
ATOM 3373 N N    . ILE A 1 228 ? 41.717 -7.701  -0.821 1.00 5.69  ? 228 ILE A N    228 ILE A N    1 
ATOM 3374 C CA   . ILE A 1 228 ? 40.559 -8.175  0.024  1.00 5.69  ? 228 ILE A CA   228 ILE A CA   1 
ATOM 3375 C C    . ILE A 1 228 ? 39.808 -9.181  -0.827 1.00 5.69  ? 228 ILE A C    228 ILE A C    1 
ATOM 3376 O O    . ILE A 1 228 ? 39.078 -8.643  -1.791 1.00 5.69  ? 228 ILE A O    228 ILE A O    1 
ATOM 3377 C CB   . ILE A 1 228 ? 39.616 -7.036  0.451  1.00 5.69  ? 228 ILE A CB   228 ILE A CB   1 
ATOM 3378 C CG1  . ILE A 1 228 ? 40.386 -5.971  1.235  1.00 5.69  ? 228 ILE A CG1  228 ILE A CG1  1 
ATOM 3379 C CG2  . ILE A 1 228 ? 38.463 -7.582  1.280  1.00 5.69  ? 228 ILE A CG2  228 ILE A CG2  1 
ATOM 3380 C CD1  . ILE A 1 228 ? 39.568 -4.742  1.562  1.00 5.69  ? 228 ILE A CD1  228 ILE A CD1  1 
ATOM 3381 H H    . ILE A 1 228 ? 41.413 -7.157  -1.492 1.00 5.69  ? 228 ILE A H    228 ILE A H    1 
ATOM 3382 H HA   . ILE A 1 228 ? 40.956 -8.626  0.932  1.00 5.69  ? 228 ILE A HA   228 ILE A HA   1 
ATOM 3383 H HB   . ILE A 1 228 ? 39.213 -6.545  -0.435 1.00 5.69  ? 228 ILE A HB   228 ILE A HB   1 
ATOM 3384 H HG12 . ILE A 1 228 ? 40.749 -6.398  2.170  1.00 5.69  ? 228 ILE A HG12 228 ILE A 1HG1 1 
ATOM 3385 H HG13 . ILE A 1 228 ? 41.258 -5.655  0.661  1.00 5.69  ? 228 ILE A HG13 228 ILE A 2HG1 1 
ATOM 3386 H HG21 . ILE A 1 228 ? 37.807 -6.764  1.574  1.00 5.69  ? 228 ILE A HG21 228 ILE A 1HG2 1 
ATOM 3387 H HG22 . ILE A 1 228 ? 37.901 -8.304  0.689  1.00 5.69  ? 228 ILE A HG22 228 ILE A 2HG2 1 
ATOM 3388 H HG23 . ILE A 1 228 ? 38.856 -8.071  2.172  1.00 5.69  ? 228 ILE A HG23 228 ILE A 3HG2 1 
ATOM 3389 H HD11 . ILE A 1 228 ? 40.182 -4.033  2.118  1.00 5.69  ? 228 ILE A HD11 228 ILE A 1HD1 1 
ATOM 3390 H HD12 . ILE A 1 228 ? 39.224 -4.277  0.638  1.00 5.69  ? 228 ILE A HD12 228 ILE A 2HD1 1 
ATOM 3391 H HD13 . ILE A 1 228 ? 38.709 -5.028  2.167  1.00 5.69  ? 228 ILE A HD13 228 ILE A 3HD1 1 
ATOM 3392 N N    . SER A 1 229 ? 40.103 -10.729 -0.523 1.00 5.91  ? 229 SER A N    229 SER A N    1 
ATOM 3393 C CA   . SER A 1 229 ? 39.435 -11.655 -1.274 1.00 5.91  ? 229 SER A CA   229 SER A CA   1 
ATOM 3394 C C    . SER A 1 229 ? 38.066 -11.959 -0.598 1.00 5.91  ? 229 SER A C    229 SER A C    1 
ATOM 3395 O O    . SER A 1 229 ? 37.867 -12.080 0.451  1.00 5.91  ? 229 SER A O    229 SER A O    1 
ATOM 3396 C CB   . SER A 1 229 ? 40.296 -12.896 -1.406 1.00 5.91  ? 229 SER A CB   229 SER A CB   1 
ATOM 3397 O OG   . SER A 1 229 ? 39.647 -13.879 -2.166 1.00 5.91  ? 229 SER A OG   229 SER A OG   1 
ATOM 3398 H H    . SER A 1 229 ? 40.517 -10.957 0.268  1.00 5.91  ? 229 SER A H    229 SER A H    1 
ATOM 3399 H HA   . SER A 1 229 ? 39.254 -11.233 -2.263 1.00 5.91  ? 229 SER A HA   229 SER A HA   1 
ATOM 3400 H HB2  . SER A 1 229 ? 41.242 -12.634 -1.878 1.00 5.91  ? 229 SER A HB2  229 SER A 1HB  1 
ATOM 3401 H HB3  . SER A 1 229 ? 40.522 -13.289 -0.416 1.00 5.91  ? 229 SER A HB3  229 SER A 2HB  1 
ATOM 3402 H HG   . SER A 1 229 ? 39.039 -14.318 -1.567 1.00 5.91  ? 229 SER A HG   229 SER A HG   1 
ATOM 3403 N N    . SER A 1 230 ? 37.139 -12.215 -1.159 1.00 5.99  ? 230 SER A N    230 SER A N    1 
ATOM 3404 C CA   . SER A 1 230 ? 35.727 -12.603 -0.677 1.00 5.99  ? 230 SER A CA   230 SER A CA   1 
ATOM 3405 C C    . SER A 1 230 ? 35.210 -11.536 0.333  1.00 5.99  ? 230 SER A C    230 SER A C    1 
ATOM 3406 O O    . SER A 1 230 ? 35.050 -11.946 1.657  1.00 5.99  ? 230 SER A O    230 SER A O    1 
ATOM 3407 C CB   . SER A 1 230 ? 35.725 -13.968 -0.017 1.00 5.99  ? 230 SER A CB   230 SER A CB   1 
ATOM 3408 O OG   . SER A 1 230 ? 36.142 -14.960 -0.914 1.00 5.99  ? 230 SER A OG   230 SER A OG   1 
ATOM 3409 H H    . SER A 1 230 ? 37.233 -12.186 -2.164 1.00 5.99  ? 230 SER A H    230 SER A H    1 
ATOM 3410 H HA   . SER A 1 230 ? 35.064 -12.641 -1.542 1.00 5.99  ? 230 SER A HA   230 SER A HA   1 
ATOM 3411 H HB2  . SER A 1 230 ? 36.387 -13.955 0.848  1.00 5.99  ? 230 SER A HB2  230 SER A 1HB  1 
ATOM 3412 H HB3  . SER A 1 230 ? 34.722 -14.197 0.342  1.00 5.99  ? 230 SER A HB3  230 SER A 2HB  1 
ATOM 3413 H HG   . SER A 1 230 ? 35.732 -14.745 -1.756 1.00 5.99  ? 230 SER A HG   230 SER A HG   1 
ATOM 3414 N N    . LEU A 1 231 ? 35.174 -10.114 -0.293 1.00 5.91  ? 231 LEU A N    231 LEU A N    1 
ATOM 3415 C CA   . LEU A 1 231 ? 34.624 -9.111  0.616  1.00 5.91  ? 231 LEU A CA   231 LEU A CA   1 
ATOM 3416 C C    . LEU A 1 231 ? 33.257 -9.517  1.158  1.00 5.91  ? 231 LEU A C    231 LEU A C    1 
ATOM 3417 O O    . LEU A 1 231 ? 32.468 -9.940  0.219  1.00 5.91  ? 231 LEU A O    231 LEU A O    1 
ATOM 3418 C CB   . LEU A 1 231 ? 34.510 -7.761  -0.102 1.00 5.91  ? 231 LEU A CB   231 LEU A CB   1 
ATOM 3419 C CG   . LEU A 1 231 ? 33.802 -6.648  0.682  1.00 5.91  ? 231 LEU A CG   231 LEU A CG   1 
ATOM 3420 C CD1  . LEU A 1 231 ? 34.578 -5.347  0.531  1.00 5.91  ? 231 LEU A CD1  231 LEU A CD1  1 
ATOM 3421 C CD2  . LEU A 1 231 ? 32.376 -6.497  0.174  1.00 5.91  ? 231 LEU A CD2  231 LEU A CD2  1 
ATOM 3422 H H    . LEU A 1 231 ? 35.370 -9.804  -1.147 1.00 5.91  ? 231 LEU A H    231 LEU A H    1 
ATOM 3423 H HA   . LEU A 1 231 ? 35.301 -9.005  1.463  1.00 5.91  ? 231 LEU A HA   231 LEU A HA   1 
ATOM 3424 H HB2  . LEU A 1 231 ? 35.512 -7.410  -0.343 1.00 5.91  ? 231 LEU A HB2  231 LEU A 1HB  1 
ATOM 3425 H HB3  . LEU A 1 231 ? 33.965 -7.907  -1.034 1.00 5.91  ? 231 LEU A HB3  231 LEU A 2HB  1 
ATOM 3426 H HG   . LEU A 1 231 ? 33.785 -6.905  1.742  1.00 5.91  ? 231 LEU A HG   231 LEU A HG   1 
ATOM 3427 H HD11 . LEU A 1 231 ? 34.075 -4.556  1.088  1.00 5.91  ? 231 LEU A HD11 231 LEU A 1HD1 1 
ATOM 3428 H HD12 . LEU A 1 231 ? 35.588 -5.478  0.920  1.00 5.91  ? 231 LEU A HD12 231 LEU A 2HD1 1 
ATOM 3429 H HD13 . LEU A 1 231 ? 34.626 -5.073  -0.522 1.00 5.91  ? 231 LEU A HD13 231 LEU A 3HD1 1 
ATOM 3430 H HD21 . LEU A 1 231 ? 31.873 -5.707  0.733  1.00 5.91  ? 231 LEU A HD21 231 LEU A 1HD2 1 
ATOM 3431 H HD22 . LEU A 1 231 ? 32.392 -6.240  -0.885 1.00 5.91  ? 231 LEU A HD22 231 LEU A 2HD2 1 
ATOM 3432 H HD23 . LEU A 1 231 ? 31.840 -7.436  0.311  1.00 5.91  ? 231 LEU A HD23 231 LEU A 3HD2 1 
ATOM 3433 N N    . GLN A 1 232 ? 33.087 -9.355  2.702  1.00 6.05  ? 232 GLN A N    232 GLN A N    1 
ATOM 3434 C CA   . GLN A 1 232 ? 31.978 -9.599  3.419  1.00 6.05  ? 232 GLN A CA   232 GLN A CA   1 
ATOM 3435 C C    . GLN A 1 232 ? 31.485 -8.183  3.808  1.00 6.05  ? 232 GLN A C    232 GLN A C    1 
ATOM 3436 O O    . GLN A 1 232 ? 32.326 -7.104  3.510  1.00 6.05  ? 232 GLN A O    232 GLN A O    1 
ATOM 3437 C CB   . GLN A 1 232 ? 32.293 -10.495 4.620  1.00 6.05  ? 232 GLN A CB   232 GLN A CB   1 
ATOM 3438 C CG   . GLN A 1 232 ? 32.940 -11.820 4.256  1.00 6.05  ? 232 GLN A CG   232 GLN A CG   1 
ATOM 3439 C CD   . GLN A 1 232 ? 32.044 -12.681 3.386  1.00 6.05  ? 232 GLN A CD   232 GLN A CD   1 
ATOM 3440 O OE1  . GLN A 1 232 ? 30.906 -12.985 3.753  1.00 6.05  ? 232 GLN A OE1  232 GLN A OE1  1 
ATOM 3441 N NE2  . GLN A 1 232 ? 32.553 -13.080 2.226  1.00 6.05  ? 232 GLN A NE2  232 GLN A NE2  1 
ATOM 3442 H H    . GLN A 1 232 ? 33.872 -8.986  3.213  1.00 6.05  ? 232 GLN A H    232 GLN A H    1 
ATOM 3443 H HA   . GLN A 1 232 ? 31.261 -10.116 2.781  1.00 6.05  ? 232 GLN A HA   232 GLN A HA   1 
ATOM 3444 H HB2  . GLN A 1 232 ? 32.964 -9.969  5.300  1.00 6.05  ? 232 GLN A HB2  232 GLN A 1HB  1 
ATOM 3445 H HB3  . GLN A 1 232 ? 31.374 -10.707 5.166  1.00 6.05  ? 232 GLN A HB3  232 GLN A 2HB  1 
ATOM 3446 H HG2  . GLN A 1 232 ? 33.862 -11.624 3.708  1.00 6.05  ? 232 GLN A HG2  232 GLN A 1HG  1 
ATOM 3447 H HG3  . GLN A 1 232 ? 33.158 -12.370 5.171  1.00 6.05  ? 232 GLN A HG3  232 GLN A 2HG  1 
ATOM 3448 H HE21 . GLN A 1 232 ? 32.009 -13.651 1.610  1.00 6.05  ? 232 GLN A HE21 232 GLN A 1HE2 1 
ATOM 3449 H HE22 . GLN A 1 232 ? 33.481 -12.811 1.968  1.00 6.05  ? 232 GLN A HE22 232 GLN A 2HE2 1 
ATOM 3450 N N    . ALA A 1 233 ? 30.083 -8.240  4.351  1.00 6.20  ? 233 ALA A N    233 ALA A N    1 
ATOM 3451 C CA   . ALA A 1 233 ? 29.549 -6.956  4.884  1.00 6.20  ? 233 ALA A CA   233 ALA A CA   1 
ATOM 3452 C C    . ALA A 1 233 ? 30.362 -6.346  5.971  1.00 6.20  ? 233 ALA A C    233 ALA A C    1 
ATOM 3453 O O    . ALA A 1 233 ? 30.365 -4.960  5.959  1.00 6.20  ? 233 ALA A O    233 ALA A O    1 
ATOM 3454 C CB   . ALA A 1 233 ? 28.128 -7.143  5.397  1.00 6.20  ? 233 ALA A CB   233 ALA A CB   1 
ATOM 3455 H H    . ALA A 1 233 ? 29.557 -9.103  4.410  1.00 6.20  ? 233 ALA A H    233 ALA A H    1 
ATOM 3456 H HA   . ALA A 1 233 ? 29.537 -6.230  4.071  1.00 6.20  ? 233 ALA A HA   233 ALA A HA   1 
ATOM 3457 H HB1  . ALA A 1 233 ? 27.754 -6.196  5.785  1.00 6.20  ? 233 ALA A HB1  233 ALA A 1HB  1 
ATOM 3458 H HB2  . ALA A 1 233 ? 27.489 -7.480  4.581  1.00 6.20  ? 233 ALA A HB2  233 ALA A 2HB  1 
ATOM 3459 H HB3  . ALA A 1 233 ? 28.124 -7.887  6.192  1.00 6.20  ? 233 ALA A HB3  233 ALA A 3HB  1 
ATOM 3460 N N    . GLU A 1 234 ? 31.077 -7.421  6.788  1.00 6.17  ? 234 GLU A N    234 GLU A N    1 
ATOM 3461 C CA   . GLU A 1 234 ? 31.981 -6.866  7.920  1.00 6.17  ? 234 GLU A CA   234 GLU A CA   1 
ATOM 3462 C C    . GLU A 1 234 ? 33.159 -6.073  7.363  1.00 6.17  ? 234 GLU A C    234 GLU A C    1 
ATOM 3463 O O    . GLU A 1 234 ? 33.858 -5.274  8.252  1.00 6.17  ? 234 GLU A O    234 GLU A O    1 
ATOM 3464 C CB   . GLU A 1 234 ? 32.532 -7.988  8.803  1.00 6.17  ? 234 GLU A CB   234 GLU A CB   1 
ATOM 3465 C CG   . GLU A 1 234 ? 33.573 -8.868  8.127  1.00 6.17  ? 234 GLU A CG   234 GLU A CG   1 
ATOM 3466 C CD   . GLU A 1 234 ? 34.058 -9.985  9.008  1.00 6.17  ? 234 GLU A CD   234 GLU A CD   1 
ATOM 3467 O OE1  . GLU A 1 234 ? 33.241 -10.731 9.492  1.00 6.17  ? 234 GLU A OE1  234 GLU A OE1  1 
ATOM 3468 O OE2  . GLU A 1 234 ? 35.246 -10.093 9.198  1.00 6.17  ? 234 GLU A OE2  234 GLU A OE2  1 
ATOM 3469 H H    . GLU A 1 234 ? 30.931 -8.411  6.627  1.00 6.17  ? 234 GLU A H    234 GLU A H    1 
ATOM 3470 H HA   . GLU A 1 234 ? 31.383 -6.204  8.547  1.00 6.17  ? 234 GLU A HA   234 GLU A HA   1 
ATOM 3471 H HB2  . GLU A 1 234 ? 32.986 -7.559  9.697  1.00 6.17  ? 234 GLU A HB2  234 GLU A 1HB  1 
ATOM 3472 H HB3  . GLU A 1 234 ? 31.713 -8.630  9.129  1.00 6.17  ? 234 GLU A HB3  234 GLU A 2HB  1 
ATOM 3473 H HG2  . GLU A 1 234 ? 33.141 -9.295  7.223  1.00 6.17  ? 234 GLU A HG2  234 GLU A 1HG  1 
ATOM 3474 H HG3  . GLU A 1 234 ? 34.420 -8.249  7.834  1.00 6.17  ? 234 GLU A HG3  234 GLU A 2HG  1 
ATOM 3475 N N    . ASP A 1 235 ? 33.348 -6.263  5.861  1.00 5.93  ? 235 ASP A N    235 ASP A N    1 
ATOM 3476 C CA   . ASP A 1 235 ? 34.554 -5.473  5.358  1.00 5.93  ? 235 ASP A CA   235 ASP A CA   1 
ATOM 3477 C C    . ASP A 1 235 ? 34.135 -4.135  4.818  1.00 5.93  ? 235 ASP A C    235 ASP A C    1 
ATOM 3478 O O    . ASP A 1 235 ? 35.145 -3.652  4.104  1.00 5.93  ? 235 ASP A O    235 ASP A O    1 
ATOM 3479 C CB   . ASP A 1 235 ? 35.308 -6.223  4.257  1.00 5.93  ? 235 ASP A CB   235 ASP A CB   1 
ATOM 3480 C CG   . ASP A 1 235 ? 35.853 -7.567  4.723  1.00 5.93  ? 235 ASP A CG   235 ASP A CG   1 
ATOM 3481 O OD1  . ASP A 1 235 ? 36.485 -7.605  5.752  1.00 5.93  ? 235 ASP A OD1  235 ASP A OD1  1 
ATOM 3482 O OD2  . ASP A 1 235 ? 35.634 -8.542  4.044  1.00 5.93  ? 235 ASP A OD2  235 ASP A OD2  1 
ATOM 3483 H H    . ASP A 1 235 ? 32.843 -6.608  5.193  1.00 5.93  ? 235 ASP A H    235 ASP A H    1 
ATOM 3484 H HA   . ASP A 1 235 ? 35.240 -5.320  6.191  1.00 5.93  ? 235 ASP A HA   235 ASP A HA   1 
ATOM 3485 H HB2  . ASP A 1 235 ? 34.643 -6.392  3.410  1.00 5.93  ? 235 ASP A HB2  235 ASP A 1HB  1 
ATOM 3486 H HB3  . ASP A 1 235 ? 36.140 -5.613  3.905  1.00 5.93  ? 235 ASP A HB3  235 ASP A 2HB  1 
ATOM 3487 N N    . VAL A 1 236 ? 32.640 -3.653  5.018  1.00 6.09  ? 236 VAL A N    236 VAL A N    1 
ATOM 3488 C CA   . VAL A 1 236 ? 32.393 -2.335  4.540  1.00 6.09  ? 236 VAL A CA   236 VAL A CA   1 
ATOM 3489 C C    . VAL A 1 236 ? 32.646 -1.332  5.769  1.00 6.09  ? 236 VAL A C    236 VAL A C    1 
ATOM 3490 O O    . VAL A 1 236 ? 32.184 -1.321  6.772  1.00 6.09  ? 236 VAL A O    236 VAL A O    1 
ATOM 3491 C CB   . VAL A 1 236 ? 30.953 -2.234  4.003  1.00 6.09  ? 236 VAL A CB   236 VAL A CB   1 
ATOM 3492 C CG1  . VAL A 1 236 ? 30.669 -0.826  3.502  1.00 6.09  ? 236 VAL A CG1  236 VAL A CG1  1 
ATOM 3493 C CG2  . VAL A 1 236 ? 30.741 -3.254  2.894  1.00 6.09  ? 236 VAL A CG2  236 VAL A CG2  1 
ATOM 3494 H H    . VAL A 1 236 ? 31.964 -4.048  5.506  1.00 6.09  ? 236 VAL A H    236 VAL A H    1 
ATOM 3495 H HA   . VAL A 1 236 ? 33.089 -2.126  3.727  1.00 6.09  ? 236 VAL A HA   236 VAL A HA   1 
ATOM 3496 H HB   . VAL A 1 236 ? 30.256 -2.432  4.818  1.00 6.09  ? 236 VAL A HB   236 VAL A HB   1 
ATOM 3497 H HG11 . VAL A 1 236 ? 29.647 -0.772  3.126  1.00 6.09  ? 236 VAL A HG11 236 VAL A 1HG1 1 
ATOM 3498 H HG12 . VAL A 1 236 ? 30.792 -0.117  4.321  1.00 6.09  ? 236 VAL A HG12 236 VAL A 2HG1 1 
ATOM 3499 H HG13 . VAL A 1 236 ? 31.363 -0.579  2.699  1.00 6.09  ? 236 VAL A HG13 236 VAL A 3HG1 1 
ATOM 3500 H HG21 . VAL A 1 236 ? 29.721 -3.177  2.520  1.00 6.09  ? 236 VAL A HG21 236 VAL A 1HG2 1 
ATOM 3501 H HG22 . VAL A 1 236 ? 31.442 -3.059  2.082  1.00 6.09  ? 236 VAL A HG22 236 VAL A 2HG2 1 
ATOM 3502 H HG23 . VAL A 1 236 ? 30.909 -4.257  3.286  1.00 6.09  ? 236 VAL A HG23 236 VAL A 3HG2 1 
ATOM 3503 N N    . ALA A 1 237 ? 33.576 -0.661  5.802  1.00 6.16  ? 237 ALA A N    237 ALA A N    1 
ATOM 3504 C CA   . ALA A 1 237 ? 34.101 0.165   6.939  1.00 6.16  ? 237 ALA A CA   237 ALA A CA   1 
ATOM 3505 C C    . ALA A 1 237 ? 35.037 1.194   6.382  1.00 6.16  ? 237 ALA A C    237 ALA A C    1 
ATOM 3506 O O    . ALA A 1 237 ? 35.275 1.032   5.040  1.00 6.16  ? 237 ALA A O    237 ALA A O    1 
ATOM 3507 C CB   . ALA A 1 237 ? 34.817 -0.683  7.980  1.00 6.16  ? 237 ALA A CB   237 ALA A CB   1 
ATOM 3508 H H    . ALA A 1 237 ? 34.078 -0.586  4.934  1.00 6.16  ? 237 ALA A H    237 ALA A H    1 
ATOM 3509 H HA   . ALA A 1 237 ? 33.255 0.652   7.423  1.00 6.16  ? 237 ALA A HA   237 ALA A HA   1 
ATOM 3510 H HB1  . ALA A 1 237 ? 35.226 -0.037  8.757  1.00 6.16  ? 237 ALA A HB1  237 ALA A 1HB  1 
ATOM 3511 H HB2  . ALA A 1 237 ? 34.111 -1.384  8.426  1.00 6.16  ? 237 ALA A HB2  237 ALA A 2HB  1 
ATOM 3512 H HB3  . ALA A 1 237 ? 35.626 -1.236  7.506  1.00 6.16  ? 237 ALA A HB3  237 ALA A 3HB  1 
ATOM 3513 N N    . VAL A 1 238 ? 35.638 2.046   7.485  1.00 6.21  ? 238 VAL A N    238 VAL A N    1 
ATOM 3514 C CA   . VAL A 1 238 ? 36.655 3.063   7.063  1.00 6.21  ? 238 VAL A CA   238 VAL A CA   1 
ATOM 3515 C C    . VAL A 1 238 ? 37.999 2.425   7.179  1.00 6.21  ? 238 VAL A C    238 VAL A C    1 
ATOM 3516 O O    . VAL A 1 238 ? 38.388 1.775   7.994  1.00 6.21  ? 238 VAL A O    238 VAL A O    1 
ATOM 3517 C CB   . VAL A 1 238 ? 36.616 4.329   7.939  1.00 6.21  ? 238 VAL A CB   238 VAL A CB   1 
ATOM 3518 C CG1  . VAL A 1 238 ? 37.673 5.324   7.485  1.00 6.21  ? 238 VAL A CG1  238 VAL A CG1  1 
ATOM 3519 C CG2  . VAL A 1 238 ? 35.229 4.952   7.886  1.00 6.21  ? 238 VAL A CG2  238 VAL A CG2  1 
ATOM 3520 H H    . VAL A 1 238 ? 35.584 1.885   8.432  1.00 6.21  ? 238 VAL A H    238 VAL A H    1 
ATOM 3521 H HA   . VAL A 1 238 ? 36.440 3.362   6.036  1.00 6.21  ? 238 VAL A HA   238 VAL A HA   1 
ATOM 3522 H HB   . VAL A 1 238 ? 36.853 4.055   8.968  1.00 6.21  ? 238 VAL A HB   238 VAL A HB   1 
ATOM 3523 H HG11 . VAL A 1 238 ? 37.631 6.213   8.116  1.00 6.21  ? 238 VAL A HG11 238 VAL A 1HG1 1 
ATOM 3524 H HG12 . VAL A 1 238 ? 38.660 4.869   7.566  1.00 6.21  ? 238 VAL A HG12 238 VAL A 2HG1 1 
ATOM 3525 H HG13 . VAL A 1 238 ? 37.485 5.606   6.449  1.00 6.21  ? 238 VAL A HG13 238 VAL A 3HG1 1 
ATOM 3526 H HG21 . VAL A 1 238 ? 35.208 5.846   8.509  1.00 6.21  ? 238 VAL A HG21 238 VAL A 1HG2 1 
ATOM 3527 H HG22 . VAL A 1 238 ? 34.990 5.220   6.857  1.00 6.21  ? 238 VAL A HG22 238 VAL A 2HG2 1 
ATOM 3528 H HG23 . VAL A 1 238 ? 34.494 4.236   8.255  1.00 6.21  ? 238 VAL A HG23 238 VAL A 3HG2 1 
ATOM 3529 N N    . TYR A 1 239 ? 38.775 2.546   6.256  1.00 5.83  ? 239 TYR A N    239 TYR A N    1 
ATOM 3530 C CA   . TYR A 1 239 ? 40.208 1.875   6.097  1.00 5.83  ? 239 TYR A CA   239 TYR A CA   1 
ATOM 3531 C C    . TYR A 1 239 ? 41.157 3.134   6.119  1.00 5.83  ? 239 TYR A C    239 TYR A C    1 
ATOM 3532 O O    . TYR A 1 239 ? 40.912 4.159   5.270  1.00 5.83  ? 239 TYR A O    239 TYR A O    1 
ATOM 3533 C CB   . TYR A 1 239 ? 40.377 1.063   4.811  1.00 5.83  ? 239 TYR A CB   239 TYR A CB   1 
ATOM 3534 C CG   . TYR A 1 239 ? 39.502 -0.169  4.748  1.00 5.83  ? 239 TYR A CG   239 TYR A CG   1 
ATOM 3535 C CD1  . TYR A 1 239 ? 39.058 -0.642  3.522  1.00 5.83  ? 239 TYR A CD1  239 TYR A CD1  1 
ATOM 3536 C CD2  . TYR A 1 239 ? 39.142 -0.825  5.915  1.00 5.83  ? 239 TYR A CD2  239 TYR A CD2  1 
ATOM 3537 C CE1  . TYR A 1 239 ? 38.258 -1.767  3.464  1.00 5.83  ? 239 TYR A CE1  239 TYR A CE1  1 
ATOM 3538 C CE2  . TYR A 1 239 ? 38.342 -1.950  5.857  1.00 5.83  ? 239 TYR A CE2  239 TYR A CE2  1 
ATOM 3539 C CZ   . TYR A 1 239 ? 37.901 -2.421  4.638  1.00 5.83  ? 239 TYR A CZ   239 TYR A CZ   1 
ATOM 3540 O OH   . TYR A 1 239 ? 37.104 -3.541  4.580  1.00 5.83  ? 239 TYR A OH   239 TYR A OH   1 
ATOM 3541 H H    . TYR A 1 239 ? 38.499 3.348   5.799  1.00 5.83  ? 239 TYR A H    239 TYR A H    1 
ATOM 3542 H HA   . TYR A 1 239 ? 40.363 1.188   6.929  1.00 5.83  ? 239 TYR A HA   239 TYR A HA   1 
ATOM 3543 H HB2  . TYR A 1 239 ? 40.145 1.691   3.950  1.00 5.83  ? 239 TYR A HB2  239 TYR A 1HB  1 
ATOM 3544 H HB3  . TYR A 1 239 ? 41.416 0.747   4.715  1.00 5.83  ? 239 TYR A HB3  239 TYR A 2HB  1 
ATOM 3545 H HD1  . TYR A 1 239 ? 39.340 -0.126  2.604  1.00 5.83  ? 239 TYR A HD1  239 TYR A HD1  1 
ATOM 3546 H HD2  . TYR A 1 239 ? 39.490 -0.453  6.879  1.00 5.83  ? 239 TYR A HD2  239 TYR A HD2  1 
ATOM 3547 H HE1  . TYR A 1 239 ? 37.909 -2.139  2.500  1.00 5.83  ? 239 TYR A HE1  239 TYR A HE1  1 
ATOM 3548 H HE2  . TYR A 1 239 ? 38.059 -2.466  6.775  1.00 5.83  ? 239 TYR A HE2  239 TYR A HE2  1 
ATOM 3549 H HH   . TYR A 1 239 ? 36.605 -3.536  3.760  1.00 5.83  ? 239 TYR A HH   239 TYR A HH   1 
ATOM 3550 N N    . TYR A 1 240 ? 42.256 3.026   7.237  1.00 5.73  ? 240 TYR A N    240 TYR A N    1 
ATOM 3551 C CA   . TYR A 1 240 ? 43.203 3.966   7.428  1.00 5.73  ? 240 TYR A CA   240 TYR A CA   1 
ATOM 3552 C C    . TYR A 1 240 ? 44.558 3.281   7.068  1.00 5.73  ? 240 TYR A C    240 TYR A C    1 
ATOM 3553 O O    . TYR A 1 240 ? 44.606 1.946   7.005  1.00 5.73  ? 240 TYR A O    240 TYR A O    1 
ATOM 3554 C CB   . TYR A 1 240 ? 43.141 4.486   8.865  1.00 5.73  ? 240 TYR A CB   240 TYR A CB   1 
ATOM 3555 C CG   . TYR A 1 240 ? 41.900 5.297   9.167  1.00 5.73  ? 240 TYR A CG   240 TYR A CG   1 
ATOM 3556 C CD1  . TYR A 1 240 ? 41.220 5.106   10.361 1.00 5.73  ? 240 TYR A CD1  240 TYR A CD1  1 
ATOM 3557 C CD2  . TYR A 1 240 ? 41.442 6.232   8.251  1.00 5.73  ? 240 TYR A CD2  240 TYR A CD2  1 
ATOM 3558 C CE1  . TYR A 1 240 ? 40.087 5.847   10.637 1.00 5.73  ? 240 TYR A CE1  240 TYR A CE1  1 
ATOM 3559 C CE2  . TYR A 1 240 ? 40.309 6.973   8.527  1.00 5.73  ? 240 TYR A CE2  240 TYR A CE2  1 
ATOM 3560 C CZ   . TYR A 1 240 ? 39.633 6.782   9.714  1.00 5.73  ? 240 TYR A CZ   240 TYR A CZ   1 
ATOM 3561 O OH   . TYR A 1 240 ? 38.505 7.520   9.989  1.00 5.73  ? 240 TYR A OH   240 TYR A OH   1 
ATOM 3562 H H    . TYR A 1 240 ? 42.316 2.245   7.686  1.00 5.73  ? 240 TYR A H    240 TYR A H    1 
ATOM 3563 H HA   . TYR A 1 240 ? 43.012 4.793   6.744  1.00 5.73  ? 240 TYR A HA   240 TYR A HA   1 
ATOM 3564 H HB2  . TYR A 1 240 ? 43.175 3.645   9.559  1.00 5.73  ? 240 TYR A HB2  240 TYR A 1HB  1 
ATOM 3565 H HB3  . TYR A 1 240 ? 44.011 5.110   9.064  1.00 5.73  ? 240 TYR A HB3  240 TYR A 2HB  1 
ATOM 3566 H HD1  . TYR A 1 240 ? 41.580 4.371   11.082 1.00 5.73  ? 240 TYR A HD1  240 TYR A HD1  1 
ATOM 3567 H HD2  . TYR A 1 240 ? 41.976 6.382   7.312  1.00 5.73  ? 240 TYR A HD2  240 TYR A HD2  1 
ATOM 3568 H HE1  . TYR A 1 240 ? 39.553 5.697   11.575 1.00 5.73  ? 240 TYR A HE1  240 TYR A HE1  1 
ATOM 3569 H HE2  . TYR A 1 240 ? 39.949 7.707   7.806  1.00 5.73  ? 240 TYR A HE2  240 TYR A HE2  1 
ATOM 3570 H HH   . TYR A 1 240 ? 38.186 7.301   10.868 1.00 5.73  ? 240 TYR A HH   240 TYR A HH   1 
ATOM 3571 N N    . CYS A 1 241 ? 45.657 4.279   6.609  1.00 5.44  ? 241 CYS A N    241 CYS A N    1 
ATOM 3572 C CA   . CYS A 1 241 ? 46.905 3.750   6.320  1.00 5.44  ? 241 CYS A CA   241 CYS A CA   1 
ATOM 3573 C C    . CYS A 1 241 ? 47.945 4.349   7.187  1.00 5.44  ? 241 CYS A C    241 CYS A C    1 
ATOM 3574 O O    . CYS A 1 241 ? 48.126 5.583   6.801  1.00 5.44  ? 241 CYS A O    241 CYS A O    1 
ATOM 3575 C CB   . CYS A 1 241 ? 47.252 3.989   4.850  1.00 5.44  ? 241 CYS A CB   241 CYS A CB   1 
ATOM 3576 S SG   . CYS A 1 241 ? 45.822 4.351   3.803  1.00 5.44  ? 241 CYS A SG   241 CYS A SG   1 
ATOM 3577 H H    . CYS A 1 241 ? 45.585 5.164   7.119  1.00 5.44  ? 241 CYS A H    241 CYS A H    1 
ATOM 3578 H HA   . CYS A 1 241 ? 46.876 2.676   6.503  1.00 5.44  ? 241 CYS A HA   241 CYS A HA   1 
ATOM 3579 H HB2  . CYS A 1 241 ? 47.948 4.825   4.772  1.00 5.44  ? 241 CYS A HB2  241 CYS A 1HB  1 
ATOM 3580 H HB3  . CYS A 1 241 ? 47.752 3.109   4.446  1.00 5.44  ? 241 CYS A HB3  241 CYS A 2HB  1 
ATOM 3581 H HG   . CYS A 1 241 ? 46.517 4.571   2.691  1.00 5.44  ? 241 CYS A HG   241 CYS A HG   1 
ATOM 3582 N N    . GLN A 1 242 ? 48.590 3.393   8.220  1.00 5.34  ? 242 GLN A N    242 GLN A N    1 
ATOM 3583 C CA   . GLN A 1 242 ? 49.544 3.936   9.143  1.00 5.34  ? 242 GLN A CA   242 GLN A CA   1 
ATOM 3584 C C    . GLN A 1 242 ? 50.907 3.415   8.560  1.00 5.34  ? 242 GLN A C    242 GLN A C    1 
ATOM 3585 O O    . GLN A 1 242 ? 51.152 2.335   8.100  1.00 5.34  ? 242 GLN A O    242 GLN A O    1 
ATOM 3586 C CB   . GLN A 1 242 ? 49.289 3.468   10.578 1.00 5.34  ? 242 GLN A CB   242 GLN A CB   1 
ATOM 3587 C CG   . GLN A 1 242 ? 50.260 4.034   11.600 1.00 5.34  ? 242 GLN A CG   242 GLN A CG   1 
ATOM 3588 C CD   . GLN A 1 242 ? 50.073 3.424   12.976 1.00 5.34  ? 242 GLN A CD   242 GLN A CD   1 
ATOM 3589 O OE1  . GLN A 1 242 ? 50.194 2.209   13.154 1.00 5.34  ? 242 GLN A OE1  242 GLN A OE1  1 
ATOM 3590 N NE2  . GLN A 1 242 ? 49.776 4.266   13.959 1.00 5.34  ? 242 GLN A NE2  242 GLN A NE2  1 
ATOM 3591 H H    . GLN A 1 242 ? 48.401 2.464   8.206  1.00 5.34  ? 242 GLN A H    242 GLN A H    1 
ATOM 3592 H HA   . GLN A 1 242 ? 49.462 5.023   9.126  1.00 5.34  ? 242 GLN A HA   242 GLN A HA   1 
ATOM 3593 H HB2  . GLN A 1 242 ? 48.280 3.752   10.879 1.00 5.34  ? 242 GLN A HB2  242 GLN A 1HB  1 
ATOM 3594 H HB3  . GLN A 1 242 ? 49.349 2.381   10.623 1.00 5.34  ? 242 GLN A HB3  242 GLN A 2HB  1 
ATOM 3595 H HG2  . GLN A 1 242 ? 51.279 3.828   11.270 1.00 5.34  ? 242 GLN A HG2  242 GLN A 1HG  1 
ATOM 3596 H HG3  . GLN A 1 242 ? 50.104 5.110   11.678 1.00 5.34  ? 242 GLN A HG3  242 GLN A 2HG  1 
ATOM 3597 H HE21 . GLN A 1 242 ? 49.641 3.922   14.890 1.00 5.34  ? 242 GLN A HE21 242 GLN A 1HE2 1 
ATOM 3598 H HE22 . GLN A 1 242 ? 49.687 5.244   13.771 1.00 5.34  ? 242 GLN A HE22 242 GLN A 2HE2 1 
ATOM 3599 N N    . GLN A 1 243 ? 51.892 4.259   8.469  1.00 4.79  ? 243 GLN A N    243 GLN A N    1 
ATOM 3600 C CA   . GLN A 1 243 ? 53.267 4.008   8.088  1.00 4.79  ? 243 GLN A CA   243 GLN A CA   1 
ATOM 3601 C C    . GLN A 1 243 ? 54.139 4.268   9.224  1.00 4.79  ? 243 GLN A C    243 GLN A C    1 
ATOM 3602 O O    . GLN A 1 243 ? 53.798 5.382   9.810  1.00 4.79  ? 243 GLN A O    243 GLN A O    1 
ATOM 3603 C CB   . GLN A 1 243 ? 53.698 4.877   6.903  1.00 4.79  ? 243 GLN A CB   243 GLN A CB   1 
ATOM 3604 C CG   . GLN A 1 243 ? 52.787 4.774   5.692  1.00 4.79  ? 243 GLN A CG   243 GLN A CG   1 
ATOM 3605 C CD   . GLN A 1 243 ? 51.518 5.591   5.851  1.00 4.79  ? 243 GLN A CD   243 GLN A CD   1 
ATOM 3606 O OE1  . GLN A 1 243 ? 51.563 6.766   6.223  1.00 4.79  ? 243 GLN A OE1  243 GLN A OE1  1 
ATOM 3607 N NE2  . GLN A 1 243 ? 50.378 4.971   5.568  1.00 4.79  ? 243 GLN A NE2  243 GLN A NE2  1 
ATOM 3608 H H    . GLN A 1 243 ? 51.705 5.164   8.650  1.00 4.79  ? 243 GLN A H    243 GLN A H    1 
ATOM 3609 H HA   . GLN A 1 243 ? 53.358 2.964   7.790  1.00 4.79  ? 243 GLN A HA   243 GLN A HA   1 
ATOM 3610 H HB2  . GLN A 1 243 ? 53.731 5.922   7.211  1.00 4.79  ? 243 GLN A HB2  243 GLN A 1HB  1 
ATOM 3611 H HB3  . GLN A 1 243 ? 54.704 4.596   6.592  1.00 4.79  ? 243 GLN A HB3  243 GLN A 2HB  1 
ATOM 3612 H HG2  . GLN A 1 243 ? 53.322 5.140   4.815  1.00 4.79  ? 243 GLN A HG2  243 GLN A 1HG  1 
ATOM 3613 H HG3  . GLN A 1 243 ? 52.506 3.730   5.549  1.00 4.79  ? 243 GLN A HG3  243 GLN A 2HG  1 
ATOM 3614 H HE21 . GLN A 1 243 ? 49.508 5.460   5.654  1.00 4.79  ? 243 GLN A HE21 243 GLN A 1HE2 1 
ATOM 3615 H HE22 . GLN A 1 243 ? 50.387 4.017   5.269  1.00 4.79  ? 243 GLN A HE22 243 GLN A 2HE2 1 
ATOM 3616 N N    . TYR A 1 244 ? 55.262 3.259   9.450  1.00 4.78  ? 244 TYR A N    244 TYR A N    1 
ATOM 3617 C CA   . TYR A 1 244 ? 56.160 3.335   10.562 1.00 4.78  ? 244 TYR A CA   244 TYR A CA   1 
ATOM 3618 C C    . TYR A 1 244 ? 57.613 3.221   10.032 1.00 4.78  ? 244 TYR A C    244 TYR A C    1 
ATOM 3619 O O    . TYR A 1 244 ? 57.898 2.422   8.959  1.00 4.78  ? 244 TYR A O    244 TYR A O    1 
ATOM 3620 C CB   . TYR A 1 244 ? 55.842 2.240   11.582 1.00 4.78  ? 244 TYR A CB   244 TYR A CB   1 
ATOM 3621 C CG   . TYR A 1 244 ? 56.892 2.085   12.660 1.00 4.78  ? 244 TYR A CG   244 TYR A CG   1 
ATOM 3622 C CD1  . TYR A 1 244 ? 57.105 3.109   13.572 1.00 4.78  ? 244 TYR A CD1  244 TYR A CD1  1 
ATOM 3623 C CD2  . TYR A 1 244 ? 57.641 0.921   12.736 1.00 4.78  ? 244 TYR A CD2  244 TYR A CD2  1 
ATOM 3624 C CE1  . TYR A 1 244 ? 58.064 2.968   14.556 1.00 4.78  ? 244 TYR A CE1  244 TYR A CE1  1 
ATOM 3625 C CE2  . TYR A 1 244 ? 58.600 0.780   13.720 1.00 4.78  ? 244 TYR A CE2  244 TYR A CE2  1 
ATOM 3626 C CZ   . TYR A 1 244 ? 58.812 1.798   14.628 1.00 4.78  ? 244 TYR A CZ   244 TYR A CZ   1 
ATOM 3627 O OH   . TYR A 1 244 ? 59.767 1.658   15.608 1.00 4.78  ? 244 TYR A OH   244 TYR A OH   1 
ATOM 3628 H H    . TYR A 1 244 ? 55.373 2.588   8.874  1.00 4.78  ? 244 TYR A H    244 TYR A H    1 
ATOM 3629 H HA   . TYR A 1 244 ? 56.035 4.306   11.042 1.00 4.78  ? 244 TYR A HA   244 TYR A HA   1 
ATOM 3630 H HB2  . TYR A 1 244 ? 54.888 2.458   12.065 1.00 4.78  ? 244 TYR A HB2  244 TYR A 1HB  1 
ATOM 3631 H HB3  . TYR A 1 244 ? 55.738 1.284   11.069 1.00 4.78  ? 244 TYR A HB3  244 TYR A 2HB  1 
ATOM 3632 H HD1  . TYR A 1 244 ? 56.516 4.024   13.512 1.00 4.78  ? 244 TYR A HD1  244 TYR A HD1  1 
ATOM 3633 H HD2  . TYR A 1 244 ? 57.474 0.117   12.019 1.00 4.78  ? 244 TYR A HD2  244 TYR A HD2  1 
ATOM 3634 H HE1  . TYR A 1 244 ? 58.231 3.772   15.273 1.00 4.78  ? 244 TYR A HE1  244 TYR A HE1  1 
ATOM 3635 H HE2  . TYR A 1 244 ? 59.190 -0.135  13.780 1.00 4.78  ? 244 TYR A HE2  244 TYR A HE2  1 
ATOM 3636 H HH   . TYR A 1 244 ? 59.834 2.475   16.108 1.00 4.78  ? 244 TYR A HH   244 TYR A HH   1 
ATOM 3637 N N    . TYR A 1 245 ? 58.446 4.417   10.470 1.00 4.35  ? 245 TYR A N    245 TYR A N    1 
ATOM 3638 C CA   . TYR A 1 245 ? 59.725 4.543   9.713  1.00 4.35  ? 245 TYR A CA   245 TYR A CA   1 
ATOM 3639 C C    . TYR A 1 245 ? 60.804 4.361   10.602 1.00 4.35  ? 245 TYR A C    245 TYR A C    1 
ATOM 3640 O O    . TYR A 1 245 ? 61.874 4.841   10.020 1.00 4.35  ? 245 TYR A O    245 TYR A O    1 
ATOM 3641 C CB   . TYR A 1 245 ? 59.884 5.899   9.021  1.00 4.35  ? 245 TYR A CB   245 TYR A CB   1 
ATOM 3642 C CG   . TYR A 1 245 ? 58.620 6.399   8.357  1.00 4.35  ? 245 TYR A CG   245 TYR A CG   1 
ATOM 3643 C CD1  . TYR A 1 245 ? 57.618 6.979   9.122  1.00 4.35  ? 245 TYR A CD1  245 TYR A CD1  1 
ATOM 3644 C CD2  . TYR A 1 245 ? 58.463 6.276   6.985  1.00 4.35  ? 245 TYR A CD2  245 TYR A CD2  1 
ATOM 3645 C CE1  . TYR A 1 245 ? 56.464 7.435   8.516  1.00 4.35  ? 245 TYR A CE1  245 TYR A CE1  1 
ATOM 3646 C CE2  . TYR A 1 245 ? 57.308 6.733   6.379  1.00 4.35  ? 245 TYR A CE2  245 TYR A CE2  1 
ATOM 3647 C CZ   . TYR A 1 245 ? 56.311 7.310   7.139  1.00 4.35  ? 245 TYR A CZ   245 TYR A CZ   1 
ATOM 3648 O OH   . TYR A 1 245 ? 55.162 7.764   6.536  1.00 4.35  ? 245 TYR A OH   245 TYR A OH   1 
ATOM 3649 H H    . TYR A 1 245 ? 58.396 4.842   9.550  1.00 4.35  ? 245 TYR A H    245 TYR A H    1 
ATOM 3650 H HA   . TYR A 1 245 ? 59.744 3.779   8.936  1.00 4.35  ? 245 TYR A HA   245 TYR A HA   1 
ATOM 3651 H HB2  . TYR A 1 245 ? 60.203 6.645   9.751  1.00 4.35  ? 245 TYR A HB2  245 TYR A 1HB  1 
ATOM 3652 H HB3  . TYR A 1 245 ? 60.663 5.830   8.262  1.00 4.35  ? 245 TYR A HB3  245 TYR A 2HB  1 
ATOM 3653 H HD1  . TYR A 1 245 ? 57.742 7.075   10.201 1.00 4.35  ? 245 TYR A HD1  245 TYR A HD1  1 
ATOM 3654 H HD2  . TYR A 1 245 ? 59.249 5.819   6.385  1.00 4.35  ? 245 TYR A HD2  245 TYR A HD2  1 
ATOM 3655 H HE1  . TYR A 1 245 ? 55.677 7.891   9.116  1.00 4.35  ? 245 TYR A HE1  245 TYR A HE1  1 
ATOM 3656 H HE2  . TYR A 1 245 ? 57.184 6.636   5.300  1.00 4.35  ? 245 TYR A HE2  245 TYR A HE2  1 
ATOM 3657 H HH   . TYR A 1 245 ? 54.782 8.471   7.063  1.00 4.35  ? 245 TYR A HH   245 TYR A HH   1 
ATOM 3658 N N    . SER A 1 246 ? 60.506 3.532   11.849 1.00 5.63  ? 246 SER A N    246 SER A N    1 
ATOM 3659 C CA   . SER A 1 246 ? 61.402 3.120   12.906 1.00 5.63  ? 246 SER A CA   246 SER A CA   1 
ATOM 3660 C C    . SER A 1 246 ? 61.207 4.087   14.182 1.00 5.63  ? 246 SER A C    246 SER A C    1 
ATOM 3661 O O    . SER A 1 246 ? 61.973 3.714   15.148 1.00 5.63  ? 246 SER A O    246 SER A O    1 
ATOM 3662 C CB   . SER A 1 246 ? 62.828 3.151   12.392 1.00 5.63  ? 246 SER A CB   246 SER A CB   1 
ATOM 3663 O OG   . SER A 1 246 ? 63.270 4.469   12.217 1.00 5.63  ? 246 SER A OG   246 SER A OG   1 
ATOM 3664 H H    . SER A 1 246 ? 59.547 3.321   12.019 1.00 5.63  ? 246 SER A H    246 SER A H    1 
ATOM 3665 H HA   . SER A 1 246 ? 61.147 2.100   13.198 1.00 5.63  ? 246 SER A HA   246 SER A HA   1 
ATOM 3666 H HB2  . SER A 1 246 ? 63.480 2.637   13.098 1.00 5.63  ? 246 SER A HB2  246 SER A 1HB  1 
ATOM 3667 H HB3  . SER A 1 246 ? 62.885 2.617   11.445 1.00 5.63  ? 246 SER A HB3  246 SER A 2HB  1 
ATOM 3668 H HG   . SER A 1 246 ? 63.037 4.709   11.317 1.00 5.63  ? 246 SER A HG   246 SER A HG   1 
ATOM 3669 N N    . THR A 1 247 ? 60.402 5.552   14.096 1.00 6.83  ? 247 THR A N    247 THR A N    1 
ATOM 3670 C CA   . THR A 1 247 ? 60.173 5.750   15.446 1.00 6.83  ? 247 THR A CA   247 THR A CA   1 
ATOM 3671 C C    . THR A 1 247 ? 58.823 6.564   14.928 1.00 6.83  ? 247 THR A C    247 THR A C    1 
ATOM 3672 O O    . THR A 1 247 ? 57.573 6.191   15.277 1.00 6.83  ? 247 THR A O    247 THR A O    1 
ATOM 3673 C CB   . THR A 1 247 ? 61.244 6.548   16.214 1.00 6.83  ? 247 THR A CB   247 THR A CB   1 
ATOM 3674 O OG1  . THR A 1 247 ? 62.539 5.994   15.948 1.00 6.83  ? 247 THR A OG1  247 THR A OG1  1 
ATOM 3675 C CG2  . THR A 1 247 ? 60.974 6.500   17.710 1.00 6.83  ? 247 THR A CG2  247 THR A CG2  1 
ATOM 3676 H H    . THR A 1 247 ? 60.039 6.073   13.314 1.00 6.83  ? 247 THR A H    247 THR A H    1 
ATOM 3677 H HA   . THR A 1 247 ? 60.124 4.777   15.936 1.00 6.83  ? 247 THR A HA   247 THR A HA   1 
ATOM 3678 H HB   . THR A 1 247 ? 61.232 7.586   15.881 1.00 6.83  ? 247 THR A HB   247 THR A HB   1 
ATOM 3679 H HG1  . THR A 1 247 ? 62.480 5.035   15.938 1.00 6.83  ? 247 THR A HG1  247 THR A HG1  1 
ATOM 3680 H HG21 . THR A 1 247 ? 61.739 7.070   18.236 1.00 6.83  ? 247 THR A HG21 247 THR A 1HG2 1 
ATOM 3681 H HG22 . THR A 1 247 ? 59.994 6.932   17.917 1.00 6.83  ? 247 THR A HG22 247 THR A 2HG2 1 
ATOM 3682 H HG23 . THR A 1 247 ? 60.993 5.466   18.050 1.00 6.83  ? 247 THR A HG23 247 THR A 3HG2 1 
ATOM 3683 N N    . PRO A 1 248 ? 59.196 7.556   13.790 1.00 5.43  ? 248 PRO A N    248 PRO A N    1 
ATOM 3684 C CA   . PRO A 1 248 ? 58.093 8.245   13.312 1.00 5.43  ? 248 PRO A CA   248 PRO A CA   1 
ATOM 3685 C C    . PRO A 1 248 ? 56.863 7.404   12.822 1.00 5.43  ? 248 PRO A C    248 PRO A C    1 
ATOM 3686 O O    . PRO A 1 248 ? 57.183 6.260   12.160 1.00 5.43  ? 248 PRO A O    248 PRO A O    1 
ATOM 3687 C CB   . PRO A 1 248 ? 58.757 9.011   12.163 1.00 5.43  ? 248 PRO A CB   248 PRO A CB   1 
ATOM 3688 C CG   . PRO A 1 248 ? 60.123 9.322   12.673 1.00 5.43  ? 248 PRO A CG   248 PRO A CG   1 
ATOM 3689 C CD   . PRO A 1 248 ? 60.551 8.067   13.387 1.00 5.43  ? 248 PRO A CD   248 PRO A CD   1 
ATOM 3690 H HA   . PRO A 1 248 ? 57.713 8.912   14.100 1.00 5.43  ? 248 PRO A HA   248 PRO A HA   1 
ATOM 3691 H HB2  . PRO A 1 248 ? 58.772 8.389   11.256 1.00 5.43  ? 248 PRO A HB2  248 PRO A 1HB  1 
ATOM 3692 H HB3  . PRO A 1 248 ? 58.175 9.913   11.926 1.00 5.43  ? 248 PRO A HB3  248 PRO A 2HB  1 
ATOM 3693 H HG2  . PRO A 1 248 ? 60.790 9.581   11.838 1.00 5.43  ? 248 PRO A HG2  248 PRO A 1HG  1 
ATOM 3694 H HG3  . PRO A 1 248 ? 60.090 10.197  13.338 1.00 5.43  ? 248 PRO A HG3  248 PRO A 2HG  1 
ATOM 3695 H HD2  . PRO A 1 248 ? 61.063 7.398   12.680 1.00 5.43  ? 248 PRO A HD2  248 PRO A 1HD  1 
ATOM 3696 H HD3  . PRO A 1 248 ? 61.216 8.330   14.224 1.00 5.43  ? 248 PRO A HD3  248 PRO A 2HD  1 
ATOM 3697 N N    . TYR A 1 249 ? 55.466 8.016   13.200 1.00 5.48  ? 249 TYR A N    249 TYR A N    1 
ATOM 3698 C CA   . TYR A 1 249 ? 54.396 7.461   12.582 1.00 5.48  ? 249 TYR A CA   249 TYR A CA   1 
ATOM 3699 C C    . TYR A 1 249 ? 53.828 8.522   11.684 1.00 5.48  ? 249 TYR A C    249 TYR A C    1 
ATOM 3700 O O    . TYR A 1 249 ? 54.101 9.735   12.112 1.00 5.48  ? 249 TYR A O    249 TYR A O    1 
ATOM 3701 C CB   . TYR A 1 249 ? 53.382 6.953   13.610 1.00 5.48  ? 249 TYR A CB   249 TYR A CB   1 
ATOM 3702 C CG   . TYR A 1 249 ? 53.827 5.706   14.342 1.00 5.48  ? 249 TYR A CG   249 TYR A CG   1 
ATOM 3703 C CD1  . TYR A 1 249 ? 54.619 5.813   15.476 1.00 5.48  ? 249 TYR A CD1  249 TYR A CD1  1 
ATOM 3704 C CD2  . TYR A 1 249 ? 53.442 4.457   13.879 1.00 5.48  ? 249 TYR A CD2  249 TYR A CD2  1 
ATOM 3705 C CE1  . TYR A 1 249 ? 55.025 4.674   16.144 1.00 5.48  ? 249 TYR A CE1  249 TYR A CE1  1 
ATOM 3706 C CE2  . TYR A 1 249 ? 53.848 3.318   14.547 1.00 5.48  ? 249 TYR A CE2  249 TYR A CE2  1 
ATOM 3707 C CZ   . TYR A 1 249 ? 54.637 3.424   15.675 1.00 5.48  ? 249 TYR A CZ   249 TYR A CZ   1 
ATOM 3708 O OH   . TYR A 1 249 ? 55.041 2.289   16.341 1.00 5.48  ? 249 TYR A OH   249 TYR A OH   1 
ATOM 3709 H H    . TYR A 1 249 ? 55.355 8.781   13.888 1.00 5.48  ? 249 TYR A H    249 TYR A H    1 
ATOM 3710 H HA   . TYR A 1 249 ? 54.740 6.614   11.988 1.00 5.48  ? 249 TYR A HA   249 TYR A HA   1 
ATOM 3711 H HB2  . TYR A 1 249 ? 53.193 7.733   14.350 1.00 5.48  ? 249 TYR A HB2  249 TYR A 1HB  1 
ATOM 3712 H HB3  . TYR A 1 249 ? 52.437 6.737   13.113 1.00 5.48  ? 249 TYR A HB3  249 TYR A 2HB  1 
ATOM 3713 H HD1  . TYR A 1 249 ? 54.921 6.795   15.839 1.00 5.48  ? 249 TYR A HD1  249 TYR A HD1  1 
ATOM 3714 H HD2  . TYR A 1 249 ? 52.821 4.373   12.988 1.00 5.48  ? 249 TYR A HD2  249 TYR A HD2  1 
ATOM 3715 H HE1  . TYR A 1 249 ? 55.648 4.757   17.034 1.00 5.48  ? 249 TYR A HE1  249 TYR A HE1  1 
ATOM 3716 H HE2  . TYR A 1 249 ? 53.547 2.335   14.183 1.00 5.48  ? 249 TYR A HE2  249 TYR A HE2  1 
ATOM 3717 H HH   . TYR A 1 249 ? 54.892 1.522   15.783 1.00 5.48  ? 249 TYR A HH   249 TYR A HH   1 
ATOM 3718 N N    . THR A 1 250 ? 53.044 7.980   10.463 1.00 5.34  ? 250 THR A N    250 THR A N    1 
ATOM 3719 C CA   . THR A 1 250 ? 52.230 8.797   9.669  1.00 5.34  ? 250 THR A CA   250 THR A CA   1 
ATOM 3720 C C    . THR A 1 250 ? 50.912 8.012   9.575  1.00 5.34  ? 250 THR A C    250 THR A C    1 
ATOM 3721 O O    . THR A 1 250 ? 51.038 6.682   9.473  1.00 5.34  ? 250 THR A O    250 THR A O    1 
ATOM 3722 C CB   . THR A 1 250 ? 52.850 9.076   8.288  1.00 5.34  ? 250 THR A CB   250 THR A CB   1 
ATOM 3723 O OG1  . THR A 1 250 ? 54.220 9.469   8.447  1.00 5.34  ? 250 THR A OG1  250 THR A OG1  1 
ATOM 3724 C CG2  . THR A 1 250 ? 52.089 10.182  7.574  1.00 5.34  ? 250 THR A CG2  250 THR A CG2  1 
ATOM 3725 H H    . THR A 1 250 ? 53.198 7.104   10.199 1.00 5.34  ? 250 THR A H    250 THR A H    1 
ATOM 3726 H HA   . THR A 1 250 ? 52.102 9.755   10.176 1.00 5.34  ? 250 THR A HA   250 THR A HA   1 
ATOM 3727 H HB   . THR A 1 250 ? 52.815 8.170   7.684  1.00 5.34  ? 250 THR A HB   250 THR A HB   1 
ATOM 3728 H HG1  . THR A 1 250 ? 54.257 10.363  8.796  1.00 5.34  ? 250 THR A HG1  250 THR A HG1  1 
ATOM 3729 H HG21 . THR A 1 250 ? 52.541 10.365  6.600  1.00 5.34  ? 250 THR A HG21 250 THR A 1HG2 1 
ATOM 3730 H HG22 . THR A 1 250 ? 51.050 9.881   7.441  1.00 5.34  ? 250 THR A HG22 250 THR A 2HG2 1 
ATOM 3731 H HG23 . THR A 1 250 ? 52.129 11.094  8.169  1.00 5.34  ? 250 THR A HG23 250 THR A 3HG2 1 
ATOM 3732 N N    . PHE A 1 251 ? 49.666 8.837   9.610  1.00 6.00  ? 251 PHE A N    251 PHE A N    1 
ATOM 3733 C CA   . PHE A 1 251 ? 48.399 8.243   9.613  1.00 6.00  ? 251 PHE A CA   251 PHE A CA   1 
ATOM 3734 C C    . PHE A 1 251 ? 47.491 8.862   8.609  1.00 6.00  ? 251 PHE A C    251 PHE A C    1 
ATOM 3735 O O    . PHE A 1 251 ? 47.003 9.970   9.007  1.00 6.00  ? 251 PHE A O    251 PHE A O    1 
ATOM 3736 C CB   . PHE A 1 251 ? 47.781 8.348   11.009 1.00 6.00  ? 251 PHE A CB   251 PHE A CB   1 
ATOM 3737 C CG   . PHE A 1 251 ? 46.618 7.422   11.228 1.00 6.00  ? 251 PHE A CG   251 PHE A CG   1 
ATOM 3738 C CD1  . PHE A 1 251 ? 46.802 6.184   11.824 1.00 6.00  ? 251 PHE A CD1  251 PHE A CD1  1 
ATOM 3739 C CD2  . PHE A 1 251 ? 45.339 7.788   10.837 1.00 6.00  ? 251 PHE A CD2  251 PHE A CD2  1 
ATOM 3740 C CE1  . PHE A 1 251 ? 45.733 5.331   12.025 1.00 6.00  ? 251 PHE A CE1  251 PHE A CE1  1 
ATOM 3741 C CE2  . PHE A 1 251 ? 44.268 6.939   11.039 1.00 6.00  ? 251 PHE A CE2  251 PHE A CE2  1 
ATOM 3742 C CZ   . PHE A 1 251 ? 44.466 5.708   11.633 1.00 6.00  ? 251 PHE A CZ   251 PHE A CZ   1 
ATOM 3743 H H    . PHE A 1 251 ? 49.727 9.848   9.641  1.00 6.00  ? 251 PHE A H    251 PHE A H    1 
ATOM 3744 H HA   . PHE A 1 251 ? 48.510 7.190   9.353  1.00 6.00  ? 251 PHE A HA   251 PHE A HA   1 
ATOM 3745 H HB2  . PHE A 1 251 ? 48.538 8.126   11.759 1.00 6.00  ? 251 PHE A HB2  251 PHE A 1HB  1 
ATOM 3746 H HB3  . PHE A 1 251 ? 47.440 9.368   11.180 1.00 6.00  ? 251 PHE A HB3  251 PHE A 2HB  1 
ATOM 3747 H HD1  . PHE A 1 251 ? 47.804 5.886   12.135 1.00 6.00  ? 251 PHE A HD1  251 PHE A HD1  1 
ATOM 3748 H HD2  . PHE A 1 251 ? 45.183 8.759   10.367 1.00 6.00  ? 251 PHE A HD2  251 PHE A HD2  1 
ATOM 3749 H HE1  . PHE A 1 251 ? 45.892 4.361   12.495 1.00 6.00  ? 251 PHE A HE1  251 PHE A HE1  1 
ATOM 3750 H HE2  . PHE A 1 251 ? 43.268 7.238   10.728 1.00 6.00  ? 251 PHE A HE2  251 PHE A HE2  1 
ATOM 3751 H HZ   . PHE A 1 251 ? 43.623 5.037   11.791 1.00 6.00  ? 251 PHE A HZ   251 PHE A HZ   1 
ATOM 3752 N N    . GLY A 1 252 ? 47.408 8.142   7.284  1.00 6.08  ? 252 GLY A N    252 GLY A N    1 
ATOM 3753 C CA   . GLY A 1 252 ? 46.764 8.659   6.151  1.00 6.08  ? 252 GLY A CA   252 GLY A CA   1 
ATOM 3754 C C    . GLY A 1 252 ? 45.295 8.212   6.701  1.00 6.08  ? 252 GLY A C    252 GLY A C    1 
ATOM 3755 O O    . GLY A 1 252 ? 44.862 7.075   7.332  1.00 6.08  ? 252 GLY A O    252 GLY A O    1 
ATOM 3756 H H    . GLY A 1 252 ? 47.684 7.293   7.254  1.00 6.08  ? 252 GLY A H    252 GLY A H    1 
ATOM 3757 H HA2  . GLY A 1 252 ? 46.985 9.722   6.060  1.00 6.08  ? 252 GLY A HA2  252 GLY A 1HA  1 
ATOM 3758 H HA3  . GLY A 1 252 ? 47.155 8.172   5.258  1.00 6.08  ? 252 GLY A HA3  252 GLY A 2HA  1 
ATOM 3759 N N    . GLN A 1 253 ? 44.403 9.073   6.148  1.00 7.02  ? 253 GLN A N    253 GLN A N    1 
ATOM 3760 C CA   . GLN A 1 253 ? 42.913 8.766   6.453  1.00 7.02  ? 253 GLN A CA   253 GLN A CA   1 
ATOM 3761 C C    . GLN A 1 253 ? 42.812 8.016   5.138  1.00 7.02  ? 253 GLN A C    253 GLN A C    1 
ATOM 3762 O O    . GLN A 1 253 ? 42.992 8.912   4.120  1.00 7.02  ? 253 GLN A O    253 GLN A O    1 
ATOM 3763 C CB   . GLN A 1 253 ? 41.964 9.962   6.572  1.00 7.02  ? 253 GLN A CB   253 GLN A CB   1 
ATOM 3764 C CG   . GLN A 1 253 ? 42.407 11.011  7.578  1.00 7.02  ? 253 GLN A CG   253 GLN A CG   1 
ATOM 3765 C CD   . GLN A 1 253 ? 42.304 10.520  9.009  1.00 7.02  ? 253 GLN A CD   253 GLN A CD   1 
ATOM 3766 O OE1  . GLN A 1 253 ? 41.260 10.017  9.435  1.00 7.02  ? 253 GLN A OE1  253 GLN A OE1  1 
ATOM 3767 N NE2  . GLN A 1 253 ? 43.389 10.662  9.762  1.00 7.02  ? 253 GLN A NE2  253 GLN A NE2  1 
ATOM 3768 H H    . GLN A 1 253 ? 44.818 9.862   5.642  1.00 7.02  ? 253 GLN A H    253 GLN A H    1 
ATOM 3769 H HA   . GLN A 1 253 ? 42.855 8.255   7.414  1.00 7.02  ? 253 GLN A HA   253 GLN A HA   1 
ATOM 3770 H HB2  . GLN A 1 253 ? 41.867 10.447  5.601  1.00 7.02  ? 253 GLN A HB2  253 GLN A 1HB  1 
ATOM 3771 H HB3  . GLN A 1 253 ? 40.974 9.613   6.864  1.00 7.02  ? 253 GLN A HB3  253 GLN A 2HB  1 
ATOM 3772 H HG2  . GLN A 1 253 ? 43.446 11.273  7.380  1.00 7.02  ? 253 GLN A HG2  253 GLN A 1HG  1 
ATOM 3773 H HG3  . GLN A 1 253 ? 41.773 11.891  7.472  1.00 7.02  ? 253 GLN A HG3  253 GLN A 2HG  1 
ATOM 3774 H HE21 . GLN A 1 253 ? 43.381 10.356  10.715 1.00 7.02  ? 253 GLN A HE21 253 GLN A 1HE2 1 
ATOM 3775 H HE22 . GLN A 1 253 ? 44.215 11.074  9.377  1.00 7.02  ? 253 GLN A HE22 253 GLN A 2HE2 1 
ATOM 3776 N N    . GLY A 1 254 ? 42.320 6.602   4.927  1.00 6.09  ? 254 GLY A N    254 GLY A N    1 
ATOM 3777 C CA   . GLY A 1 254 ? 42.203 6.264   3.571  1.00 6.09  ? 254 GLY A CA   254 GLY A CA   1 
ATOM 3778 C C    . GLY A 1 254 ? 40.883 6.382   2.875  1.00 6.09  ? 254 GLY A C    254 GLY A C    1 
ATOM 3779 O O    . GLY A 1 254 ? 40.904 6.954   1.590  1.00 6.09  ? 254 GLY A O    254 GLY A O    1 
ATOM 3780 H H    . GLY A 1 254 ? 41.956 5.802   5.255  1.00 6.09  ? 254 GLY A H    254 GLY A H    1 
ATOM 3781 H HA2  . GLY A 1 254 ? 42.884 6.879   2.983  1.00 6.09  ? 254 GLY A HA2  254 GLY A 1HA  1 
ATOM 3782 H HA3  . GLY A 1 254 ? 42.501 5.226   3.428  1.00 6.09  ? 254 GLY A HA3  254 GLY A 2HA  1 
ATOM 3783 N N    . THR A 1 255 ? 39.597 6.578   3.595  1.00 7.44  ? 255 THR A N    255 THR A N    1 
ATOM 3784 C CA   . THR A 1 255 ? 38.451 6.754   4.302  1.00 7.44  ? 255 THR A CA   255 THR A CA   1 
ATOM 3785 C C    . THR A 1 255 ? 37.368 5.830   4.047  1.00 7.44  ? 255 THR A C    255 THR A C    1 
ATOM 3786 O O    . THR A 1 255 ? 37.694 4.527   4.301  1.00 7.44  ? 255 THR A O    255 THR A O    1 
ATOM 3787 C CB   . THR A 1 255 ? 37.938 8.187   4.070  1.00 7.44  ? 255 THR A CB   255 THR A CB   1 
ATOM 3788 O OG1  . THR A 1 255 ? 37.632 8.369   2.682  1.00 7.44  ? 255 THR A OG1  255 THR A OG1  1 
ATOM 3789 C CG2  . THR A 1 255 ? 38.988 9.204   4.492  1.00 7.44  ? 255 THR A CG2  255 THR A CG2  1 
ATOM 3790 H H    . THR A 1 255 ? 40.149 5.949   4.230  1.00 7.44  ? 255 THR A H    255 THR A H    1 
ATOM 3791 H HA   . THR A 1 255 ? 38.673 6.615   5.360  1.00 7.44  ? 255 THR A HA   255 THR A HA   1 
ATOM 3792 H HB   . THR A 1 255 ? 37.031 8.348   4.652  1.00 7.44  ? 255 THR A HB   255 THR A HB   1 
ATOM 3793 H HG1  . THR A 1 255 ? 36.681 8.323   2.555  1.00 7.44  ? 255 THR A HG1  255 THR A HG1  1 
ATOM 3794 H HG21 . THR A 1 255 ? 38.608 10.211  4.321  1.00 7.44  ? 255 THR A HG21 255 THR A 1HG2 1 
ATOM 3795 H HG22 . THR A 1 255 ? 39.214 9.076   5.550  1.00 7.44  ? 255 THR A HG22 255 THR A 2HG2 1 
ATOM 3796 H HG23 . THR A 1 255 ? 39.894 9.055   3.907  1.00 7.44  ? 255 THR A HG23 255 THR A 3HG2 1 
ATOM 3797 N N    . LYS A 1 256 ? 36.106 6.540   3.635  1.00 7.61  ? 256 LYS A N    256 LYS A N    1 
ATOM 3798 C CA   . LYS A 1 256 ? 34.866 5.390   3.918  1.00 7.61  ? 256 LYS A CA   256 LYS A CA   1 
ATOM 3799 C C    . LYS A 1 256 ? 34.385 4.752   2.634  1.00 7.61  ? 256 LYS A C    256 LYS A C    1 
ATOM 3800 O O    . LYS A 1 256 ? 34.026 5.736   1.752  1.00 7.61  ? 256 LYS A O    256 LYS A O    1 
ATOM 3801 C CB   . LYS A 1 256 ? 33.621 5.968   4.592  1.00 7.61  ? 256 LYS A CB   256 LYS A CB   1 
ATOM 3802 C CG   . LYS A 1 256 ? 32.458 4.992   4.708  1.00 7.61  ? 256 LYS A CG   256 LYS A CG   1 
ATOM 3803 C CD   . LYS A 1 256 ? 32.748 3.906   5.733  1.00 7.61  ? 256 LYS A CD   256 LYS A CD   1 
ATOM 3804 C CE   . LYS A 1 256 ? 31.628 2.877   5.782  1.00 7.61  ? 256 LYS A CE   256 LYS A CE   1 
ATOM 3805 N NZ   . LYS A 1 256 ? 30.333 3.482   6.193  1.00 7.61  ? 256 LYS A NZ   256 LYS A NZ   1 
ATOM 3806 H H    . LYS A 1 256 ? 36.058 7.377   3.046  1.00 7.61  ? 256 LYS A H    256 LYS A H    1 
ATOM 3807 H HA   . LYS A 1 256 ? 35.256 4.618   4.582  1.00 7.61  ? 256 LYS A HA   256 LYS A HA   1 
ATOM 3808 H HB2  . LYS A 1 256 ? 33.875 6.307   5.597  1.00 7.61  ? 256 LYS A HB2  256 LYS A 1HB  1 
ATOM 3809 H HB3  . LYS A 1 256 ? 33.274 6.837   4.032  1.00 7.61  ? 256 LYS A HB3  256 LYS A 2HB  1 
ATOM 3810 H HG2  . LYS A 1 256 ? 31.558 5.532   5.008  1.00 7.61  ? 256 LYS A HG2  256 LYS A 1HG  1 
ATOM 3811 H HG3  . LYS A 1 256 ? 32.275 4.527   3.740  1.00 7.61  ? 256 LYS A HG3  256 LYS A 2HG  1 
ATOM 3812 H HD2  . LYS A 1 256 ? 33.682 3.404   5.478  1.00 7.61  ? 256 LYS A HD2  256 LYS A 1HD  1 
ATOM 3813 H HD3  . LYS A 1 256 ? 32.856 4.357   6.720  1.00 7.61  ? 256 LYS A HD3  256 LYS A 2HD  1 
ATOM 3814 H HE2  . LYS A 1 256 ? 31.508 2.424   4.799  1.00 7.61  ? 256 LYS A HE2  256 LYS A 1HE  1 
ATOM 3815 H HE3  . LYS A 1 256 ? 31.888 2.090   6.490  1.00 7.61  ? 256 LYS A HE3  256 LYS A 2HE  1 
ATOM 3816 H HZ1  . LYS A 1 256 ? 29.618 2.768   6.214  1.00 7.61  ? 256 LYS A HZ1  256 LYS A 1HZ  1 
ATOM 3817 H HZ2  . LYS A 1 256 ? 30.428 3.889   7.113  1.00 7.61  ? 256 LYS A HZ2  256 LYS A 2HZ  1 
ATOM 3818 H HZ3  . LYS A 1 256 ? 30.071 4.200   5.533  1.00 7.61  ? 256 LYS A HZ3  256 LYS A 3HZ  1 
ATOM 3819 N N    . VAL A 1 257 ? 34.055 3.261   2.652  1.00 7.22  ? 257 VAL A N    257 VAL A N    1 
ATOM 3820 C CA   . VAL A 1 257 ? 33.603 2.769   1.355  1.00 7.22  ? 257 VAL A CA   257 VAL A CA   1 
ATOM 3821 C C    . VAL A 1 257 ? 32.639 3.455   0.601  1.00 7.22  ? 257 VAL A C    257 VAL A C    1 
ATOM 3822 O O    . VAL A 1 257 ? 33.175 3.600   -0.610 1.00 7.22  ? 257 VAL A O    257 VAL A O    1 
ATOM 3823 C CB   . VAL A 1 257 ? 33.025 1.350   1.513  1.00 7.22  ? 257 VAL A CB   257 VAL A CB   1 
ATOM 3824 C CG1  . VAL A 1 257 ? 32.337 0.909   0.230  1.00 7.22  ? 257 VAL A CG1  257 VAL A CG1  1 
ATOM 3825 C CG2  . VAL A 1 257 ? 34.132 0.379   1.894  1.00 7.22  ? 257 VAL A CG2  257 VAL A CG2  1 
ATOM 3826 H H    . VAL A 1 257 ? 34.204 2.662   3.380  1.00 7.22  ? 257 VAL A H    257 VAL A H    1 
ATOM 3827 H HA   . VAL A 1 257 ? 34.460 2.731   0.681  1.00 7.22  ? 257 VAL A HA   257 VAL A HA   1 
ATOM 3828 H HB   . VAL A 1 257 ? 32.266 1.363   2.296  1.00 7.22  ? 257 VAL A HB   257 VAL A HB   1 
ATOM 3829 H HG11 . VAL A 1 257 ? 31.934 -0.096  0.360  1.00 7.22  ? 257 VAL A HG11 257 VAL A 1HG1 1 
ATOM 3830 H HG12 . VAL A 1 257 ? 31.525 1.597   -0.003 1.00 7.22  ? 257 VAL A HG12 257 VAL A 2HG1 1 
ATOM 3831 H HG13 . VAL A 1 257 ? 33.059 0.906   -0.587 1.00 7.22  ? 257 VAL A HG13 257 VAL A 3HG1 1 
ATOM 3832 H HG21 . VAL A 1 257 ? 33.716 -0.621  2.005  1.00 7.22  ? 257 VAL A HG21 257 VAL A 1HG2 1 
ATOM 3833 H HG22 . VAL A 1 257 ? 34.893 0.372   1.113  1.00 7.22  ? 257 VAL A HG22 257 VAL A 2HG2 1 
ATOM 3834 H HG23 . VAL A 1 257 ? 34.582 0.692   2.836  1.00 7.22  ? 257 VAL A HG23 257 VAL A 3HG2 1 
ATOM 3835 N N    . GLU A 1 258 ? 31.400 3.937   1.324  1.00 8.47  ? 258 GLU A N    258 GLU A N    1 
ATOM 3836 C CA   . GLU A 1 258 ? 30.094 4.284   0.791  1.00 8.47  ? 258 GLU A CA   258 GLU A CA   1 
ATOM 3837 C C    . GLU A 1 258 ? 29.835 5.732   1.062  1.00 8.47  ? 258 GLU A C    258 GLU A C    1 
ATOM 3838 O O    . GLU A 1 258 ? 28.511 6.002   1.311  1.00 8.47  ? 258 GLU A O    258 GLU A O    1 
ATOM 3839 C CB   . GLU A 1 258 ? 28.991 3.424   1.413  1.00 8.47  ? 258 GLU A CB   258 GLU A CB   1 
ATOM 3840 C CG   . GLU A 1 258 ? 29.104 1.938   1.105  1.00 8.47  ? 258 GLU A CG   258 GLU A CG   1 
ATOM 3841 C CD   . GLU A 1 258 ? 27.916 1.150   1.585  1.00 8.47  ? 258 GLU A CD   258 GLU A CD   1 
ATOM 3842 O OE1  . GLU A 1 258 ? 27.084 1.714   2.254  1.00 8.47  ? 258 GLU A OE1  258 GLU A OE1  1 
ATOM 3843 O OE2  . GLU A 1 258 ? 27.841 -0.017  1.280  1.00 8.47  ? 258 GLU A OE2  258 GLU A OE2  1 
ATOM 3844 H H    . GLU A 1 258 ? 31.459 4.063   2.336  1.00 8.47  ? 258 GLU A H    258 GLU A H    1 
ATOM 3845 H HA   . GLU A 1 258 ? 30.100 4.104   -0.285 1.00 8.47  ? 258 GLU A HA   258 GLU A HA   1 
ATOM 3846 H HB2  . GLU A 1 258 ? 29.004 3.544   2.496  1.00 8.47  ? 258 GLU A HB2  258 GLU A 1HB  1 
ATOM 3847 H HB3  . GLU A 1 258 ? 28.019 3.767   1.057  1.00 8.47  ? 258 GLU A HB3  258 GLU A 2HB  1 
ATOM 3848 H HG2  . GLU A 1 258 ? 29.201 1.807   0.028  1.00 8.47  ? 258 GLU A HG2  258 GLU A 1HG  1 
ATOM 3849 H HG3  . GLU A 1 258 ? 30.006 1.548   1.575  1.00 8.47  ? 258 GLU A HG3  258 GLU A 2HG  1 
ATOM 3850 N N    . ILE A 1 259 ? 31.045 6.625   0.956  1.00 12.58 ? 259 ILE A N    259 ILE A N    1 
ATOM 3851 C CA   . ILE A 1 259 ? 30.720 8.096   1.068  1.00 12.58 ? 259 ILE A CA   259 ILE A CA   1 
ATOM 3852 C C    . ILE A 1 259 ? 31.544 8.440   -0.203 1.00 12.58 ? 259 ILE A C    259 ILE A C    1 
ATOM 3853 O O    . ILE A 1 259 ? 32.002 7.398   -0.910 1.00 12.58 ? 259 ILE A O    259 ILE A O    1 
ATOM 3854 C CB   . ILE A 1 259 ? 31.214 8.804   2.343  1.00 12.58 ? 259 ILE A CB   259 ILE A CB   1 
ATOM 3855 C CG1  . ILE A 1 259 ? 32.744 8.857   2.366  1.00 12.58 ? 259 ILE A CG1  259 ILE A CG1  1 
ATOM 3856 C CG2  . ILE A 1 259 ? 30.684 8.099   3.582  1.00 12.58 ? 259 ILE A CG2  259 ILE A CG2  1 
ATOM 3857 C CD1  . ILE A 1 259 ? 33.312 9.582   3.564  1.00 12.58 ? 259 ILE A CD1  259 ILE A CD1  1 
ATOM 3858 H H    . ILE A 1 259 ? 31.998 6.308   0.824  1.00 12.58 ? 259 ILE A H    259 ILE A H    1 
ATOM 3859 H HA   . ILE A 1 259 ? 29.637 8.212   1.064  1.00 12.58 ? 259 ILE A HA   259 ILE A HA   1 
ATOM 3860 H HB   . ILE A 1 259 ? 30.863 9.836   2.346  1.00 12.58 ? 259 ILE A HB   259 ILE A HB   1 
ATOM 3861 H HG12 . ILE A 1 259 ? 33.143 7.844   2.359  1.00 12.58 ? 259 ILE A HG12 259 ILE A 1HG1 1 
ATOM 3862 H HG13 . ILE A 1 259 ? 33.104 9.355   1.465  1.00 12.58 ? 259 ILE A HG13 259 ILE A 2HG1 1 
ATOM 3863 H HG21 . ILE A 1 259 ? 31.043 8.612   4.474  1.00 12.58 ? 259 ILE A HG21 259 ILE A 1HG2 1 
ATOM 3864 H HG22 . ILE A 1 259 ? 29.595 8.112   3.570  1.00 12.58 ? 259 ILE A HG22 259 ILE A 2HG2 1 
ATOM 3865 H HG23 . ILE A 1 259 ? 31.035 7.067   3.592  1.00 12.58 ? 259 ILE A HG23 259 ILE A 3HG2 1 
ATOM 3866 H HD11 . ILE A 1 259 ? 34.401 9.579   3.510  1.00 12.58 ? 259 ILE A HD11 259 ILE A 1HD1 1 
ATOM 3867 H HD12 . ILE A 1 259 ? 32.953 10.612  3.571  1.00 12.58 ? 259 ILE A HD12 259 ILE A 2HD1 1 
ATOM 3868 H HD13 . ILE A 1 259 ? 32.994 9.081   4.477  1.00 12.58 ? 259 ILE A HD13 259 ILE A 3HD1 1 
ATOM 3869 N N    . LYS A 1 260 ? 31.636 9.832   -0.573 1.00 14.15 ? 260 LYS A N    260 LYS A N    1 
ATOM 3870 C CA   . LYS A 1 260 ? 32.405 10.042  -1.835 1.00 14.15 ? 260 LYS A CA   260 LYS A CA   1 
ATOM 3871 C C    . LYS A 1 260 ? 33.913 9.462   -1.877 1.00 14.15 ? 260 LYS A C    260 LYS A C    1 
ATOM 3872 O O    . LYS A 1 260 ? 34.474 8.947   -3.028 1.00 14.15 ? 260 LYS A O    260 LYS A O    1 
ATOM 3873 C CB   . LYS A 1 260 ? 32.425 11.542  -2.130 1.00 14.15 ? 260 LYS A CB   260 LYS A CB   1 
ATOM 3874 C CG   . LYS A 1 260 ? 31.071 12.125  -2.515 1.00 14.15 ? 260 LYS A CG   260 LYS A CG   1 
ATOM 3875 C CD   . LYS A 1 260 ? 31.172 13.617  -2.794 1.00 14.15 ? 260 LYS A CD   260 LYS A CD   1 
ATOM 3876 C CE   . LYS A 1 260 ? 29.805 14.220  -3.086 1.00 14.15 ? 260 LYS A CE   260 LYS A CE   1 
ATOM 3877 N NZ   . LYS A 1 260 ? 29.896 15.665  -3.430 1.00 14.15 ? 260 LYS A NZ   260 LYS A NZ   1 
ATOM 3878 H H    . LYS A 1 260 ? 31.253 10.534  -0.006 1.00 14.15 ? 260 LYS A H    260 LYS A H    1 
ATOM 3879 H HA   . LYS A 1 260 ? 31.898 9.512   -2.642 1.00 14.15 ? 260 LYS A HA   260 LYS A HA   1 
ATOM 3880 H HB2  . LYS A 1 260 ? 32.783 12.081  -1.252 1.00 14.15 ? 260 LYS A HB2  260 LYS A 1HB  1 
ATOM 3881 H HB3  . LYS A 1 260 ? 33.120 11.744  -2.945 1.00 14.15 ? 260 LYS A HB3  260 LYS A 2HB  1 
ATOM 3882 H HG2  . LYS A 1 260 ? 30.698 11.621  -3.407 1.00 14.15 ? 260 LYS A HG2  260 LYS A 1HG  1 
ATOM 3883 H HG3  . LYS A 1 260 ? 30.361 11.963  -1.704 1.00 14.15 ? 260 LYS A HG3  260 LYS A 2HG  1 
ATOM 3884 H HD2  . LYS A 1 260 ? 31.605 14.121  -1.929 1.00 14.15 ? 260 LYS A HD2  260 LYS A 1HD  1 
ATOM 3885 H HD3  . LYS A 1 260 ? 31.822 13.784  -3.653 1.00 14.15 ? 260 LYS A HD3  260 LYS A 2HD  1 
ATOM 3886 H HE2  . LYS A 1 260 ? 29.344 13.689  -3.917 1.00 14.15 ? 260 LYS A HE2  260 LYS A 1HE  1 
ATOM 3887 H HE3  . LYS A 1 260 ? 29.164 14.107  -2.212 1.00 14.15 ? 260 LYS A HE3  260 LYS A 2HE  1 
ATOM 3888 H HZ1  . LYS A 1 260 ? 28.971 16.026  -3.615 1.00 14.15 ? 260 LYS A HZ1  260 LYS A 1HZ  1 
ATOM 3889 H HZ2  . LYS A 1 260 ? 30.306 16.170  -2.656 1.00 14.15 ? 260 LYS A HZ2  260 LYS A 2HZ  1 
ATOM 3890 H HZ3  . LYS A 1 260 ? 30.473 15.780  -4.250 1.00 14.15 ? 260 LYS A HZ3  260 LYS A 3HZ  1 
ATOM 3891 N N    . LYS A 1 261 ? 34.571 9.646   -0.666 1.00 13.90 ? 261 LYS A N    261 LYS A N    1 
ATOM 3892 C CA   . LYS A 1 261 ? 35.957 9.193   -0.525 1.00 13.90 ? 261 LYS A CA   261 LYS A CA   1 
ATOM 3893 C C    . LYS A 1 261 ? 36.110 8.220   0.428  1.00 13.90 ? 261 LYS A C    261 LYS A C    1 
ATOM 3894 O O    . LYS A 1 261 ? 35.449 8.432   1.501  1.00 13.90 ? 261 LYS A O    261 LYS A O    1 
ATOM 3895 C CB   . LYS A 1 261 ? 36.911 10.331  -0.158 1.00 13.90 ? 261 LYS A CB   261 LYS A CB   1 
ATOM 3896 C CG   . LYS A 1 261 ? 36.776 11.571  -1.032 1.00 13.90 ? 261 LYS A CG   261 LYS A CG   1 
ATOM 3897 C CD   . LYS A 1 261 ? 37.180 11.281  -2.470 1.00 13.90 ? 261 LYS A CD   261 LYS A CD   1 
ATOM 3898 C CE   . LYS A 1 261 ? 37.061 12.523  -3.340 1.00 13.90 ? 261 LYS A CE   261 LYS A CE   1 
ATOM 3899 N NZ   . LYS A 1 261 ? 37.339 12.228  -4.772 1.00 13.90 ? 261 LYS A NZ   261 LYS A NZ   1 
ATOM 3900 H H    . LYS A 1 261 ? 34.054 9.959   0.139  1.00 13.90 ? 261 LYS A H    261 LYS A H    1 
ATOM 3901 H HA   . LYS A 1 261 ? 36.285 8.781   -1.480 1.00 13.90 ? 261 LYS A HA   261 LYS A HA   1 
ATOM 3902 H HB2  . LYS A 1 261 ? 36.740 10.630  0.876  1.00 13.90 ? 261 LYS A HB2  261 LYS A 1HB  1 
ATOM 3903 H HB3  . LYS A 1 261 ? 37.941 9.980   -0.232 1.00 13.90 ? 261 LYS A HB3  261 LYS A 2HB  1 
ATOM 3904 H HG2  . LYS A 1 261 ? 35.742 11.916  -1.017 1.00 13.90 ? 261 LYS A HG2  261 LYS A 1HG  1 
ATOM 3905 H HG3  . LYS A 1 261 ? 37.411 12.364  -0.638 1.00 13.90 ? 261 LYS A HG3  261 LYS A 2HG  1 
ATOM 3906 H HD2  . LYS A 1 261 ? 38.212 10.928  -2.494 1.00 13.90 ? 261 LYS A HD2  261 LYS A 1HD  1 
ATOM 3907 H HD3  . LYS A 1 261 ? 36.538 10.500  -2.878 1.00 13.90 ? 261 LYS A HD3  261 LYS A 2HD  1 
ATOM 3908 H HE2  . LYS A 1 261 ? 36.055 12.931  -3.255 1.00 13.90 ? 261 LYS A HE2  261 LYS A 1HE  1 
ATOM 3909 H HE3  . LYS A 1 261 ? 37.766 13.279  -2.995 1.00 13.90 ? 261 LYS A HE3  261 LYS A 2HE  1 
ATOM 3910 H HZ1  . LYS A 1 261 ? 37.250 13.075  -5.315 1.00 13.90 ? 261 LYS A HZ1  261 LYS A 1HZ  1 
ATOM 3911 H HZ2  . LYS A 1 261 ? 38.278 11.865  -4.866 1.00 13.90 ? 261 LYS A HZ2  261 LYS A 2HZ  1 
ATOM 3912 H HZ3  . LYS A 1 261 ? 36.679 11.542  -5.110 1.00 13.90 ? 261 LYS A HZ3  261 LYS A 3HZ  1 
ATOM 3913 N N    . HIS A 1 262 ? 37.062 7.291   -0.034 1.00 13.02 ? 262 HIS A N    262 HIS A N    1 
ATOM 3914 C CA   . HIS A 1 262 ? 37.818 5.840   0.240  1.00 13.02 ? 262 HIS A CA   262 HIS A CA   1 
ATOM 3915 C C    . HIS A 1 262 ? 39.192 5.529   -0.321 1.00 13.02 ? 262 HIS A C    262 HIS A C    1 
ATOM 3916 O O    . HIS A 1 262 ? 39.479 6.130   -1.395 1.00 13.02 ? 262 HIS A O    262 HIS A O    1 
ATOM 3917 C CB   . HIS A 1 262 ? 36.968 4.668   -0.261 1.00 13.02 ? 262 HIS A CB   262 HIS A CB   1 
ATOM 3918 C CG   . HIS A 1 262 ? 37.050 3.451   0.607  1.00 13.02 ? 262 HIS A CG   262 HIS A CG   1 
ATOM 3919 N ND1  . HIS A 1 262 ? 37.258 3.521   1.969  1.00 13.02 ? 262 HIS A ND1  262 HIS A ND1  1 
ATOM 3920 C CD2  . HIS A 1 262 ? 36.952 2.134   0.308  1.00 13.02 ? 262 HIS A CD2  262 HIS A CD2  1 
ATOM 3921 C CE1  . HIS A 1 262 ? 37.283 2.298   2.470  1.00 13.02 ? 262 HIS A CE1  262 HIS A CE1  1 
ATOM 3922 N NE2  . HIS A 1 262 ? 37.101 1.440   1.484  1.00 13.02 ? 262 HIS A NE2  262 HIS A NE2  1 
ATOM 3923 H H    . HIS A 1 262 ? 37.270 7.625   -0.981 1.00 13.02 ? 262 HIS A H    262 HIS A H    1 
ATOM 3924 H HA   . HIS A 1 262 ? 37.971 5.705   1.311  1.00 13.02 ? 262 HIS A HA   262 HIS A HA   1 
ATOM 3925 H HB2  . HIS A 1 262 ? 35.924 4.975   -0.321 1.00 13.02 ? 262 HIS A HB2  262 HIS A 1HB  1 
ATOM 3926 H HB3  . HIS A 1 262 ? 37.286 4.392   -1.266 1.00 13.02 ? 262 HIS A HB3  262 HIS A 2HB  1 
ATOM 3927 H HD1  . HIS A 1 262 ? 37.298 4.356   2.518  1.00 13.02 ? 262 HIS A HD1  262 HIS A HD1  1 
ATOM 3928 H HD2  . HIS A 1 262 ? 36.790 1.597   -0.627 1.00 13.02 ? 262 HIS A HD2  262 HIS A HD2  1 
ATOM 3929 H HE1  . HIS A 1 262 ? 37.437 2.139   3.537  1.00 13.02 ? 262 HIS A HE1  262 HIS A HE1  1 
ATOM 3930 N N    . HIS A 1 263 ? 39.768 4.470   0.559  1.00 12.30 ? 263 HIS A N    263 HIS A N    1 
ATOM 3931 C CA   . HIS A 1 263 ? 40.746 3.434   1.214  1.00 12.30 ? 263 HIS A CA   263 HIS A CA   1 
ATOM 3932 C C    . HIS A 1 263 ? 42.481 3.180   1.609  1.00 12.30 ? 263 HIS A C    263 HIS A C    1 
ATOM 3933 O O    . HIS A 1 263 ? 43.635 3.929   1.648  1.00 12.30 ? 263 HIS A O    263 HIS A O    1 
ATOM 3934 C CB   . HIS A 1 263 ? 40.315 2.232   0.368  1.00 12.30 ? 263 HIS A CB   263 HIS A CB   1 
ATOM 3935 C CG   . HIS A 1 263 ? 40.322 2.499   -1.105 1.00 12.30 ? 263 HIS A CG   263 HIS A CG   1 
ATOM 3936 N ND1  . HIS A 1 263 ? 39.181 2.441   -1.877 1.00 12.30 ? 263 HIS A ND1  263 HIS A ND1  1 
ATOM 3937 C CD2  . HIS A 1 263 ? 41.331 2.825   -1.947 1.00 12.30 ? 263 HIS A CD2  263 HIS A CD2  1 
ATOM 3938 C CE1  . HIS A 1 263 ? 39.488 2.721   -3.132 1.00 12.30 ? 263 HIS A CE1  263 HIS A CE1  1 
ATOM 3939 N NE2  . HIS A 1 263 ? 40.785 2.957   -3.201 1.00 12.30 ? 263 HIS A NE2  263 HIS A NE2  1 
ATOM 3940 H H    . HIS A 1 263 ? 38.971 4.347   1.185  1.00 12.30 ? 263 HIS A H    263 HIS A H    1 
ATOM 3941 H HA   . HIS A 1 263 ? 40.523 3.345   2.277  1.00 12.30 ? 263 HIS A HA   263 HIS A HA   1 
ATOM 3942 H HB2  . HIS A 1 263 ? 40.980 1.390   0.566  1.00 12.30 ? 263 HIS A HB2  263 HIS A 1HB  1 
ATOM 3943 H HB3  . HIS A 1 263 ? 39.308 1.928   0.654  1.00 12.30 ? 263 HIS A HB3  263 HIS A 2HB  1 
ATOM 3944 H HD1  . HIS A 1 263 ? 38.249 2.297   -1.545 1.00 12.30 ? 263 HIS A HD1  263 HIS A HD1  1 
ATOM 3945 H HD2  . HIS A 1 263 ? 42.399 2.981   -1.798 1.00 12.30 ? 263 HIS A HD2  263 HIS A HD2  1 
ATOM 3946 H HE1  . HIS A 1 263 ? 38.718 2.728   -3.903 1.00 12.30 ? 263 HIS A HE1  263 HIS A HE1  1 
ATOM 3947 N N    . HIS A 1 264 ? 42.626 1.895   2.142  1.00 11.47 ? 264 HIS A N    264 HIS A N    1 
ATOM 3948 C CA   . HIS A 1 264 ? 44.054 1.655   2.383  1.00 11.47 ? 264 HIS A CA   264 HIS A CA   1 
ATOM 3949 C C    . HIS A 1 264 ? 45.354 1.088   1.802  1.00 11.47 ? 264 HIS A C    264 HIS A C    1 
ATOM 3950 O O    . HIS A 1 264 ? 45.523 -0.219  1.680  1.00 11.47 ? 264 HIS A O    264 HIS A O    1 
ATOM 3951 C CB   . HIS A 1 264 ? 43.969 0.898   3.713  1.00 11.47 ? 264 HIS A CB   264 HIS A CB   1 
ATOM 3952 C CG   . HIS A 1 264 ? 45.292 0.400   4.207  1.00 11.47 ? 264 HIS A CG   264 HIS A CG   1 
ATOM 3953 N ND1  . HIS A 1 264 ? 46.128 1.164   4.994  1.00 11.47 ? 264 HIS A ND1  264 HIS A ND1  1 
ATOM 3954 C CD2  . HIS A 1 264 ? 45.923 -0.784  4.025  1.00 11.47 ? 264 HIS A CD2  264 HIS A CD2  1 
ATOM 3955 C CE1  . HIS A 1 264 ? 47.217 0.470   5.276  1.00 11.47 ? 264 HIS A CE1  264 HIS A CE1  1 
ATOM 3956 N NE2  . HIS A 1 264 ? 47.117 -0.714  4.700  1.00 11.47 ? 264 HIS A NE2  264 HIS A NE2  1 
ATOM 3957 H H    . HIS A 1 264 ? 41.872 1.260   2.367  1.00 11.47 ? 264 HIS A H    264 HIS A H    1 
ATOM 3958 H HA   . HIS A 1 264 ? 44.574 2.608   2.465  1.00 11.47 ? 264 HIS A HA   264 HIS A HA   1 
ATOM 3959 H HB2  . HIS A 1 264 ? 43.543 1.550   4.476  1.00 11.47 ? 264 HIS A HB2  264 HIS A 1HB  1 
ATOM 3960 H HB3  . HIS A 1 264 ? 43.302 0.043   3.603  1.00 11.47 ? 264 HIS A HB3  264 HIS A 2HB  1 
ATOM 3961 H HD1  . HIS A 1 264 ? 45.922 2.067   5.371  1.00 11.47 ? 264 HIS A HD1  264 HIS A HD1  1 
ATOM 3962 H HD2  . HIS A 1 264 ? 45.656 -1.690  3.481  1.00 11.47 ? 264 HIS A HD2  264 HIS A HD2  1 
ATOM 3963 H HE1  . HIS A 1 264 ? 48.006 0.901   5.892  1.00 11.47 ? 264 HIS A HE1  264 HIS A HE1  1 
ATOM 3964 N N    . HIS A 1 265 ? 46.321 2.090   1.822  1.00 10.96 ? 265 HIS A N    265 HIS A N    1 
ATOM 3965 C CA   . HIS A 1 265 ? 47.895 1.649   1.925  1.00 10.96 ? 265 HIS A CA   265 HIS A CA   1 
ATOM 3966 C C    . HIS A 1 265 ? 49.448 2.398   1.978  1.00 10.96 ? 265 HIS A C    265 HIS A C    1 
ATOM 3967 O O    . HIS A 1 265 ? 50.425 1.718   1.350  1.00 10.96 ? 265 HIS A O    265 HIS A O    1 
ATOM 3968 C CB   . HIS A 1 265 ? 48.020 0.666   0.757  1.00 10.96 ? 265 HIS A CB   265 HIS A CB   1 
ATOM 3969 C CG   . HIS A 1 265 ? 48.184 -0.760  1.186  1.00 10.96 ? 265 HIS A CG   265 HIS A CG   1 
ATOM 3970 N ND1  . HIS A 1 265 ? 48.168 -1.144  2.511  1.00 10.96 ? 265 HIS A ND1  265 HIS A ND1  1 
ATOM 3971 C CD2  . HIS A 1 265 ? 48.369 -1.892  0.467  1.00 10.96 ? 265 HIS A CD2  265 HIS A CD2  1 
ATOM 3972 C CE1  . HIS A 1 265 ? 48.335 -2.453  2.587  1.00 10.96 ? 265 HIS A CE1  265 HIS A CE1  1 
ATOM 3973 N NE2  . HIS A 1 265 ? 48.459 -2.929  1.362  1.00 10.96 ? 265 HIS A NE2  265 HIS A NE2  1 
ATOM 3974 H H    . HIS A 1 265 ? 45.516 2.910   1.749  1.00 10.96 ? 265 HIS A H    265 HIS A H    1 
ATOM 3975 H HA   . HIS A 1 265 ? 48.077 1.173   2.888  1.00 10.96 ? 265 HIS A HA   265 HIS A HA   1 
ATOM 3976 H HB2  . HIS A 1 265 ? 47.132 0.732   0.128  1.00 10.96 ? 265 HIS A HB2  265 HIS A 1HB  1 
ATOM 3977 H HB3  . HIS A 1 265 ? 48.878 0.938   0.143  1.00 10.96 ? 265 HIS A HB3  265 HIS A 2HB  1 
ATOM 3978 H HD1  . HIS A 1 265 ? 47.976 -0.554  3.295  1.00 10.96 ? 265 HIS A HD1  265 HIS A HD1  1 
ATOM 3979 H HD2  . HIS A 1 265 ? 48.449 -2.084  -0.603 1.00 10.96 ? 265 HIS A HD2  265 HIS A HD2  1 
ATOM 3980 H HE1  . HIS A 1 265 ? 48.351 -2.955  3.554  1.00 10.96 ? 265 HIS A HE1  265 HIS A HE1  1 
ATOM 3981 N N    . HIS A 1 266 ? 49.984 3.407   2.894  1.00 10.80 ? 266 HIS A N    266 HIS A N    1 
ATOM 3982 C CA   . HIS A 1 266 ? 51.230 3.686   2.055  1.00 10.80 ? 266 HIS A CA   266 HIS A CA   1 
ATOM 3983 C C    . HIS A 1 266 ? 52.710 2.881   2.240  1.00 10.80 ? 266 HIS A C    266 HIS A C    1 
ATOM 3984 O O    . HIS A 1 266 ? 53.070 2.534   3.463  1.00 10.80 ? 266 HIS A O    266 HIS A O    1 
ATOM 3985 C CB   . HIS A 1 266 ? 51.481 5.189   2.210  1.00 10.80 ? 266 HIS A CB   266 HIS A CB   1 
ATOM 3986 C CG   . HIS A 1 266 ? 50.252 6.026   2.035  1.00 10.80 ? 266 HIS A CG   266 HIS A CG   1 
ATOM 3987 N ND1  . HIS A 1 266 ? 49.232 6.053   2.963  1.00 10.80 ? 266 HIS A ND1  266 HIS A ND1  1 
ATOM 3988 C CD2  . HIS A 1 266 ? 49.879 6.865   1.040  1.00 10.80 ? 266 HIS A CD2  266 HIS A CD2  1 
ATOM 3989 C CE1  . HIS A 1 266 ? 48.284 6.874   2.546  1.00 10.80 ? 266 HIS A CE1  266 HIS A CE1  1 
ATOM 3990 N NE2  . HIS A 1 266 ? 48.652 7.378   1.383  1.00 10.80 ? 266 HIS A NE2  266 HIS A NE2  1 
ATOM 3991 H H    . HIS A 1 266 ? 49.827 4.135   3.692  1.00 10.80 ? 266 HIS A H    266 HIS A H    1 
ATOM 3992 H HA   . HIS A 1 266 ? 51.032 3.432   1.014  1.00 10.80 ? 266 HIS A HA   266 HIS A HA   1 
ATOM 3993 H HB2  . HIS A 1 266 ? 51.892 5.389   3.200  1.00 10.80 ? 266 HIS A HB2  266 HIS A 1HB  1 
ATOM 3994 H HB3  . HIS A 1 266 ? 52.221 5.512   1.478  1.00 10.80 ? 266 HIS A HB3  266 HIS A 2HB  1 
ATOM 3995 H HD2  . HIS A 1 266 ? 50.445 7.090   0.136  1.00 10.80 ? 266 HIS A HD2  266 HIS A HD2  1 
ATOM 3996 H HE1  . HIS A 1 266 ? 47.357 7.097   3.073  1.00 10.80 ? 266 HIS A HE1  266 HIS A HE1  1 
ATOM 3997 H HE2  . HIS A 1 266 ? 48.121 8.036   0.829  1.00 10.80 ? 266 HIS A HE2  266 HIS A HE2  1 
ATOM 3998 N N    . HIS A 1 267 ? 53.840 2.956   1.320  1.00 10.45 ? 267 HIS A N    267 HIS A N    1 
ATOM 3999 C CA   . HIS A 1 267 ? 54.894 2.432   2.199  1.00 10.45 ? 267 HIS A CA   267 HIS A CA   1 
ATOM 4000 C C    . HIS A 1 267 ? 55.182 3.551   3.385  1.00 10.45 ? 267 HIS A C    267 HIS A C    1 
ATOM 4001 O O    . HIS A 1 267 ? 55.552 3.336   4.654  1.00 10.45 ? 267 HIS A O    267 HIS A O    1 
ATOM 4002 C CB   . HIS A 1 267 ? 56.152 2.126   1.381  1.00 10.45 ? 267 HIS A CB   267 HIS A CB   1 
ATOM 4003 C CG   . HIS A 1 267 ? 56.018 0.924   0.497  1.00 10.45 ? 267 HIS A CG   267 HIS A CG   1 
ATOM 4004 N ND1  . HIS A 1 267 ? 55.261 0.930   -0.656 1.00 10.45 ? 267 HIS A ND1  267 HIS A ND1  1 
ATOM 4005 C CD2  . HIS A 1 267 ? 56.541 -0.320  0.598  1.00 10.45 ? 267 HIS A CD2  267 HIS A CD2  1 
ATOM 4006 C CE1  . HIS A 1 267 ? 55.326 -0.260  -1.227 1.00 10.45 ? 267 HIS A CE1  267 HIS A CE1  1 
ATOM 4007 N NE2  . HIS A 1 267 ? 56.096 -1.036  -0.486 1.00 10.45 ? 267 HIS A NE2  267 HIS A NE2  1 
ATOM 4008 H H    . HIS A 1 267 ? 53.953 3.277   0.231  1.00 10.45 ? 267 HIS A H    267 HIS A H    1 
ATOM 4009 H HA   . HIS A 1 267 ? 54.553 1.508   2.665  1.00 10.45 ? 267 HIS A HA   267 HIS A HA   1 
ATOM 4010 H HB2  . HIS A 1 267 ? 56.397 2.984   0.754  1.00 10.45 ? 267 HIS A HB2  267 HIS A 1HB  1 
ATOM 4011 H HB3  . HIS A 1 267 ? 56.993 1.961   2.054  1.00 10.45 ? 267 HIS A HB3  267 HIS A 2HB  1 
ATOM 4012 H HD1  . HIS A 1 267 ? 54.800 1.722   -1.057 1.00 10.45 ? 267 HIS A HD1  267 HIS A HD1  1 
ATOM 4013 H HD2  . HIS A 1 267 ? 57.195 -0.791  1.333  1.00 10.45 ? 267 HIS A HD2  267 HIS A HD2  1 
ATOM 4014 H HE1  . HIS A 1 267 ? 54.793 -0.460  -2.156 1.00 10.45 ? 267 HIS A HE1  267 HIS A HE1  1 
ATOM 4015 N N    . CYS A 1 268 ? 55.151 4.747   2.763  1.00 10.50 ? 268 CYS A N    268 CYS A N    1 
ATOM 4016 C CA   . CYS A 1 268 ? 55.587 6.118   3.146  1.00 10.50 ? 268 CYS A CA   268 CYS A CA   1 
ATOM 4017 C C    . CYS A 1 268 ? 54.776 7.236   2.553  1.00 10.50 ? 268 CYS A C    268 CYS A C    1 
ATOM 4018 O O    . CYS A 1 268 ? 53.815 6.857   1.898  1.00 10.50 ? 268 CYS A O    268 CYS A O    1 
ATOM 4019 C CB   . CYS A 1 268 ? 57.044 6.345   2.741  1.00 10.50 ? 268 CYS A CB   268 CYS A CB   1 
ATOM 4020 S SG   . CYS A 1 268 ? 57.664 8.003   3.110  1.00 10.50 ? 268 CYS A SG   268 CYS A SG   1 
ATOM 4021 O OXT  . CYS A 1 268 ? 55.097 8.376   2.742  1.00 10.50 ? 268 CYS A OXT  268 CYS A OXT  1 
ATOM 4022 H H    . CYS A 1 268 ? 54.712 4.722   1.864  1.00 10.50 ? 268 CYS A H    268 CYS A H    1 
ATOM 4023 H HA   . CYS A 1 268 ? 55.505 6.217   4.229  1.00 10.50 ? 268 CYS A HA   268 CYS A HA   1 
ATOM 4024 H HB2  . CYS A 1 268 ? 57.681 5.624   3.256  1.00 10.50 ? 268 CYS A HB2  268 CYS A 1HB  1 
ATOM 4025 H HB3  . CYS A 1 268 ? 57.155 6.174   1.671  1.00 10.50 ? 268 CYS A HB3  268 CYS A 2HB  1 
ATOM 4026 H HG   . CYS A 1 268 ? 56.775 8.652   2.364  1.00 10.50 ? 268 CYS A HG   268 CYS A HG   1 
# 
